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The map label for this gene is hypE [H]

Identifier: 126208793

GI number: 126208793

Start: 1524124

End: 1525137

Strand: Direct

Name: hypE [H]

Synonym: APL_1329

Alternate gene names: 126208793

Gene position: 1524124-1525137 (Clockwise)

Preceding gene: 126208792

Following gene: 126208795

Centisome position: 67.01

GC content: 42.8

Gene sequence:

>1014_bases
ATGAACGATATTATTACGATGTCTCATGGAAACGGCGGATTATTAATGCAGAAACTAATCCGAGAATACTTTATGGAAGC
GTTTGATAATCCTCTGCTTTCACAGGCTGAAGATCAAGCTCGCTTACCTTTAACCGCTTTAACATCACAAGGCGACCAAC
TCGCTTTTAGTACCGATAGTTTTGTTATAGATCCGATCTTTTTCCCCGGAGGGAATATCGGTAAATTGGCAGTATGCGGC
ACAGTAAACGATGTTGTGGTAAGCGGTGCCGTTCCCCTTTACCTTTCATGCGGTTTTATTTTAGAAGAAGGTTTCCCGCT
TGAACAGCTAAAGCAAGTGATTAGCGAAATGGCAAATTGCGCTAAAAAAGCAGGTATTCAAATTGTTACCGGAGATACTA
AAGTAGTACCGAAAGGAGCGGCGGATAAAATTTTCATTAATACCAGCGGTATCGGTGTCATTCCTGCTCAAATCCAATGG
GGAATGCATCAAATTAAAACGGGCGATAAAATTATTGTAAGCGGCACATTAGGCGATCACGGCGCAACTATTCTGAATTT
ACGAGAGAAACTCGGTATCCAGACGGATCTGATTAGCGATTGTAATGTCCTAACGCCGTTAGTCGATTTACTACGCCCGA
TAGAAGGAATTAAAACCCTTAGAGATGCAACCAGAGGCGGCGTAAATGCGGTATTACACGAATTTTCACAAAGCAGCGGA
CTCGGTATGCAAATTTACCAAGATGCGTTACCTATTCGTACTGAGGTAAGGGGGATATGTGAACTGTTAGGCTTGGAAGC
GATAAACTTTGCTAATGAAGGAAAACTCGTCGTTATTACAAGTGCCGAGACGGCACAAGCTGCGTTATCCGCTCTCCAGA
CTCATCCTCTCGGAAAAGATGCTGCAATCATAGGCGAAGTTATTTCCGATAAAAAAGTTCGCTTAATCGGATCTTTCGGA
CAAAGTCGTTTATTAGATCTACCGACTATCGAACCTCTACCGCGTATTTGCTAA

Upstream 100 bases:

>100_bases
TTTGGGCAAAAATGTAACCCGAATAGTGCCTATGGTGCATTAATGGTTTCTTCTGAGGGGGCTTGTTCGGCTTACTATCA
ATATCGGAGAGAAATGTAAG

Downstream 100 bases:

>100_bases
GCAGAAACATCCGAAATATTATACCGTAAATATAACACTGTAATTTATAAGGGCGAATTTATTCGCCCTTACATTAATAT
TAATCATAGCTTGCGATCAC

Product: hydrogenase isoenzymes formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNDIITMSHGNGGLLMQKLIREYFMEAFDNPLLSQAEDQARLPLTALTSQGDQLAFSTDSFVIDPIFFPGGNIGKLAVCG
TVNDVVVSGAVPLYLSCGFILEEGFPLEQLKQVISEMANCAKKAGIQIVTGDTKVVPKGAADKIFINTSGIGVIPAQIQW
GMHQIKTGDKIIVSGTLGDHGATILNLREKLGIQTDLISDCNVLTPLVDLLRPIEGIKTLRDATRGGVNAVLHEFSQSSG
LGMQIYQDALPIRTEVRGICELLGLEAINFANEGKLVVITSAETAQAALSALQTHPLGKDAAIIGEVISDKKVRLIGSFG
QSRLLDLPTIEPLPRIC

Sequences:

>Translated_337_residues
MNDIITMSHGNGGLLMQKLIREYFMEAFDNPLLSQAEDQARLPLTALTSQGDQLAFSTDSFVIDPIFFPGGNIGKLAVCG
TVNDVVVSGAVPLYLSCGFILEEGFPLEQLKQVISEMANCAKKAGIQIVTGDTKVVPKGAADKIFINTSGIGVIPAQIQW
GMHQIKTGDKIIVSGTLGDHGATILNLREKLGIQTDLISDCNVLTPLVDLLRPIEGIKTLRDATRGGVNAVLHEFSQSSG
LGMQIYQDALPIRTEVRGICELLGLEAINFANEGKLVVITSAETAQAALSALQTHPLGKDAAIIGEVISDKKVRLIGSFG
QSRLLDLPTIEPLPRIC
>Mature_337_residues
MNDIITMSHGNGGLLMQKLIREYFMEAFDNPLLSQAEDQARLPLTALTSQGDQLAFSTDSFVIDPIFFPGGNIGKLAVCG
TVNDVVVSGAVPLYLSCGFILEEGFPLEQLKQVISEMANCAKKAGIQIVTGDTKVVPKGAADKIFINTSGIGVIPAQIQW
GMHQIKTGDKIIVSGTLGDHGATILNLREKLGIQTDLISDCNVLTPLVDLLRPIEGIKTLRDATRGGVNAVLHEFSQSSG
LGMQIYQDALPIRTEVRGICELLGLEAINFANEGKLVVITSAETAQAALSALQTHPLGKDAAIIGEVISDKKVRLIGSFG
QSRLLDLPTIEPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=64.3916913946587, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35985; Mature: 35985

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIITMSHGNGGLLMQKLIREYFMEAFDNPLLSQAEDQARLPLTALTSQGDQLAFSTDS
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCHHHHCCCCCEEEEECCC
FVIDPIFFPGGNIGKLAVCGTVNDVVVSGAVPLYLSCGFILEEGFPLEQLKQVISEMANC
EEEEEEECCCCCCCCEEEECCHHHHHHCCCCHHEEECCHHHCCCCCHHHHHHHHHHHHHH
AKKAGIQIVTGDTKVVPKGAADKIFINTSGIGVIPAQIQWGMHQIKTGDKIIVSGTLGDH
HHHCCEEEEECCCEECCCCCCCEEEEECCCCEEEEHHHHHCHHHHCCCCEEEEEECCCCC
GATILNLREKLGIQTDLISDCNVLTPLVDLLRPIEGIKTLRDATRGGVNAVLHEFSQSSG
CHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
LGMQIYQDALPIRTEVRGICELLGLEAINFANEGKLVVITSAETAQAALSALQTHPLGKD
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
AAIIGEVISDKKVRLIGSFGQSRLLDLPTIEPLPRIC
HHHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MNDIITMSHGNGGLLMQKLIREYFMEAFDNPLLSQAEDQARLPLTALTSQGDQLAFSTDS
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCHHHHCCCCCEEEEECCC
FVIDPIFFPGGNIGKLAVCGTVNDVVVSGAVPLYLSCGFILEEGFPLEQLKQVISEMANC
EEEEEEECCCCCCCCEEEECCHHHHHHCCCCHHEEECCHHHCCCCCHHHHHHHHHHHHHH
AKKAGIQIVTGDTKVVPKGAADKIFINTSGIGVIPAQIQWGMHQIKTGDKIIVSGTLGDH
HHHCCEEEEECCCEECCCCCCCEEEEECCCCEEEEHHHHHCHHHHCCCCEEEEEECCCCC
GATILNLREKLGIQTDLISDCNVLTPLVDLLRPIEGIKTLRDATRGGVNAVLHEFSQSSG
CHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
LGMQIYQDALPIRTEVRGICELLGLEAINFANEGKLVVITSAETAQAALSALQTHPLGKD
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
AAIIGEVISDKKVRLIGSFGQSRLLDLPTIEPLPRIC
HHHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]