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The map label for this gene is hypD [H]

Identifier: 126208792

GI number: 126208792

Start: 1523007

End: 1524122

Strand: Direct

Name: hypD [H]

Synonym: APL_1328

Alternate gene names: 126208792

Gene position: 1523007-1524122 (Clockwise)

Preceding gene: 126208791

Following gene: 126208793

Centisome position: 66.96

GC content: 42.2

Gene sequence:

>1116_bases
ATGCAATTTGTCGATGAATTTAGAGATCCCGTTCTGGCTCGTAAATTAATTACGCATTTACAGCAATTAATGCAAAAGTT
GCCGCAATTCAGTAAAAAACGACCGCTTTATTTGATGGAAGTATGCGGCGGTCATACCCATACGATTTTTAAATTCGGTT
TAGATCGTATTTTGCCGGAAAGTATCGAATTTATTCACGGTCCTGGTTGTCCGGTATGCGTATTACCGATGGGGCGAATT
GACGTATGTATTGAAATCGCTCGTCGCCCCGAGGTCATTTTTTGTACCTTCGGTGATGCGATGAGAGTAAAAGGCAAACT
AGGCTCTTTATTGGATGCTAAAGGACAGGGTGCCGATATTCGTATCGTCTATTCTCCCTTGGATGCACTCAATATTGCCC
GACAAAATCCGAACAAAAAAGTGGTTTTCTTTTCTCTCGGATTTGAAACGACAATGCCAAGTACGGCGATAACATTACAG
CAAGCCAAAAAGCAACAGGTAAATAACTTCTTTATTGTTTGCCAAAACATTACGATTATTCCTACATTACGAGAATTATT
ACGACAAGAGCAAGTATTAATCGACGGCTTTATCGCACCGGGTCACGTCAGTATGATTATCGGCACCGCTCCCTATCAAC
CGCTTGCCGAGCAATATCATAAACCGTTTGTGGTTACCGGCTTTGAGCCTTTAGATTTATTACAAGCGATTGTGATGCTA
GTCGAACAATTCGTCGAGAATCGTTGTGAAGTTGAAAATCAATACAAGCGGATTGTTCAATCCAACGGTAATCTAATCGC
ACAGCAGGCAATGCAAGAAGTCTTTCAATTGAAAAAAAGTAGCGAATGGCGAGGATTAGGCGAAATTGCGGAATCAGGGG
TTGAGCTTACCGAGCAGTATGCGCAATTCGATGCCGAGAAATATTTTAATACGCAGGTACATGCCGTTGCGGATGATCCT
CTCGCTCGCTGCGGAGATGTCTTAACAGGAAAATGTAAACCGAGTGATTGTCCTTTATTTGGGCAAAAATGTAACCCGAA
TAGTGCCTATGGTGCATTAATGGTTTCTTCTGAGGGGGCTTGTTCGGCTTACTATCAATATCGGAGAGAAATGTAA

Upstream 100 bases:

>100_bases
ATCCGAATATTCAAATCTTTTGTCTTTCAGCCACGTCCGGTGAAGGTATGGAAACGTGGTTGGACTGGTTGGAAAGTCAG
ACGGCTTAAGGAATTATAAA

Downstream 100 bases:

>100_bases
GATGAACGATATTATTACGATGTCTCATGGAAACGGCGGATTATTAATGCAGAAACTAATCCGAGAATACTTTATGGAAG
CGTTTGATAATCCTCTGCTT

Product: hydrogenase isoenzymes formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MQFVDEFRDPVLARKLITHLQQLMQKLPQFSKKRPLYLMEVCGGHTHTIFKFGLDRILPESIEFIHGPGCPVCVLPMGRI
DVCIEIARRPEVIFCTFGDAMRVKGKLGSLLDAKGQGADIRIVYSPLDALNIARQNPNKKVVFFSLGFETTMPSTAITLQ
QAKKQQVNNFFIVCQNITIIPTLRELLRQEQVLIDGFIAPGHVSMIIGTAPYQPLAEQYHKPFVVTGFEPLDLLQAIVML
VEQFVENRCEVENQYKRIVQSNGNLIAQQAMQEVFQLKKSSEWRGLGEIAESGVELTEQYAQFDAEKYFNTQVHAVADDP
LARCGDVLTGKCKPSDCPLFGQKCNPNSAYGALMVSSEGACSAYYQYRREM

Sequences:

>Translated_371_residues
MQFVDEFRDPVLARKLITHLQQLMQKLPQFSKKRPLYLMEVCGGHTHTIFKFGLDRILPESIEFIHGPGCPVCVLPMGRI
DVCIEIARRPEVIFCTFGDAMRVKGKLGSLLDAKGQGADIRIVYSPLDALNIARQNPNKKVVFFSLGFETTMPSTAITLQ
QAKKQQVNNFFIVCQNITIIPTLRELLRQEQVLIDGFIAPGHVSMIIGTAPYQPLAEQYHKPFVVTGFEPLDLLQAIVML
VEQFVENRCEVENQYKRIVQSNGNLIAQQAMQEVFQLKKSSEWRGLGEIAESGVELTEQYAQFDAEKYFNTQVHAVADDP
LARCGDVLTGKCKPSDCPLFGQKCNPNSAYGALMVSSEGACSAYYQYRREM
>Mature_371_residues
MQFVDEFRDPVLARKLITHLQQLMQKLPQFSKKRPLYLMEVCGGHTHTIFKFGLDRILPESIEFIHGPGCPVCVLPMGRI
DVCIEIARRPEVIFCTFGDAMRVKGKLGSLLDAKGQGADIRIVYSPLDALNIARQNPNKKVVFFSLGFETTMPSTAITLQ
QAKKQQVNNFFIVCQNITIIPTLRELLRQEQVLIDGFIAPGHVSMIIGTAPYQPLAEQYHKPFVVTGFEPLDLLQAIVML
VEQFVENRCEVENQYKRIVQSNGNLIAQQAMQEVFQLKKSSEWRGLGEIAESGVELTEQYAQFDAEKYFNTQVHAVADDP
LARCGDVLTGKCKPSDCPLFGQKCNPNSAYGALMVSSEGACSAYYQYRREM

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=370, Percent_Identity=64.8648648648649, Blast_Score=515, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41735; Mature: 41735

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFVDEFRDPVLARKLITHLQQLMQKLPQFSKKRPLYLMEVCGGHTHTIFKFGLDRILPE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHH
SIEFIHGPGCPVCVLPMGRIDVCIEIARRPEVIFCTFGDAMRVKGKLGSLLDAKGQGADI
HHHEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHCCCCCCCEE
RIVYSPLDALNIARQNPNKKVVFFSLGFETTMPSTAITLQQAKKQQVNNFFIVCQNITII
EEEECCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEC
PTLRELLRQEQVLIDGFIAPGHVSMIIGTAPYQPLAEQYHKPFVVTGFEPLDLLQAIVML
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCEEEECCCHHHHHHHHHHH
VEQFVENRCEVENQYKRIVQSNGNLIAQQAMQEVFQLKKSSEWRGLGEIAESGVELTEQY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQFDAEKYFNTQVHAVADDPLARCGDVLTGKCKPSDCPLFGQKCNPNSAYGALMVSSEGA
HHHHHHHHHCCEEEEECCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
CSAYYQYRREM
HHHHHHHHHCC
>Mature Secondary Structure
MQFVDEFRDPVLARKLITHLQQLMQKLPQFSKKRPLYLMEVCGGHTHTIFKFGLDRILPE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHH
SIEFIHGPGCPVCVLPMGRIDVCIEIARRPEVIFCTFGDAMRVKGKLGSLLDAKGQGADI
HHHEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHCCCCCCCEE
RIVYSPLDALNIARQNPNKKVVFFSLGFETTMPSTAITLQQAKKQQVNNFFIVCQNITII
EEEECCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEC
PTLRELLRQEQVLIDGFIAPGHVSMIIGTAPYQPLAEQYHKPFVVTGFEPLDLLQAIVML
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCEEEECCCHHHHHHHHHHH
VEQFVENRCEVENQYKRIVQSNGNLIAQQAMQEVFQLKKSSEWRGLGEIAESGVELTEQY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQFDAEKYFNTQVHAVADDPLARCGDVLTGKCKPSDCPLFGQKCNPNSAYGALMVSSEGA
HHHHHHHHHCCEEEEECCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
CSAYYQYRREM
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]