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The map label for this gene is pqqL [H]

Identifier: 126208624

GI number: 126208624

Start: 1329028

End: 1330542

Strand: Reverse

Name: pqqL [H]

Synonym: APL_1154

Alternate gene names: 126208624

Gene position: 1330542-1329028 (Counterclockwise)

Preceding gene: 126208625

Following gene: 126208615

Centisome position: 58.5

GC content: 43.23

Gene sequence:

>1515_bases
ATGCGTATTATTTTAACTTCTTTAGTGCTGTTTGCCGCTTCAACGACAAGTTATGCGGAAAAAAGCGAACCGATTCAAGG
GCAGCTTGAAAACGGTTTACGATATACCTTACTCCCGTTACATTCGGAAAAAGGACGAATTGAAATCCGAATGAAAGTCA
ATGCCGGAGCGATTGACGAAACCGATACGCAGTTAGGCGCAACCAATGTACTTAAGCATTTGGTGTTACGCGGCACTAAA
GCTCACCCCAACGGTTTAACGCCGTATCTAAACGAACAAAAGTGGAAGCCGGAAAATAATTATCGTATCGAGAGCGGTTA
TGATCATACCACTTACCATATGATTCCGCCTTCAACCTCCAATCTGGATAAAAGTCTCTATTTGTTGGAGCAAATGCTAT
TCCAAGCGAAGCTAACCCAAGAAGATTTGGATGACGAGCGTAAGCATATCTTGGAAGAGTGGCGACAAGCGCAGAGTGTC
GGTAGATTAATGAATCAGAAACGTATTGCGGCGGTACGTACGGATTCTCGTTATGCCGACAGAGCGATTATCGGCACAGC
GGAGAATATCCAAAATTTACCGGCGACCCAGTTGCAGCAGTTTTATCAAACGTGGTACACGCCGAATAATATGCAGCTAT
TAGTGGTCGGCGATATCGAGCCGGAAGCGGCGCAACAACAAATTCAGCAACGCTTCTCGAGTTTTACAGCTAAAGAAATG
CCGAAAAGAGATTATTTAGAGCCGAAATTATCCGAAGGATTAGCGATTAATAAACTCCAAGATGCGCGTAGTAGTGTCAG
CCAAGTCGCATATATTTTCCGTTTTGACGAAATGAAACATCGAGTGCGTACTAATGAAGCGCGCTACGAGCGTTTAATTG
ATCGTTTGGCACTAGCGTTATTGTCGCAACGGTTACAGGATCAATCCGCCGCTTTGCCTAAAGGCGTGTCCGCTATAACG
GTACGTAAATCCGATATCGGTAGAAATACCGCCGCATTAGGTTGGTTTGCGACGGTTGCATCAACGCAACATGAGTTAGG
CTTAAAACAAATTTTTAGCGAAATAGAGCATCTCAAAGGTTCGCCTATTACCGAAGAGGAACTGACCAAACAAAAAGAAG
CGGTTCAAATTCAGATAGAAAATGCTAAAAAAGATGAAAACGATCGAGATTTCCAACAGTGGTTACAAATCATGTCGGAA
AGCGTATTAGCGGATAAGCCGTATTTAACGCAGAAGAAATTGGCGGAATTATTGGAACCGATGCTGAAAAAAGTCTCGGC
TAAAGAAGTAAATGAAAGAATCCAACAATGGATTGGCAGCAAAGATCGTTTAATCAATTACCAACCGCCAAGAAAGGTGC
AGATAAAACCAATTACATTAGAAACGGTAAATAAGTTGCAAGCGGAAGCGGAACAAACAGAGCTAGCAAAGACAGAAGCG
GAGAAAACGGAAGTGGAAAAAGCAGAAGTAGAAAAAACGGAAGCGACTCAGCCGGCTACCGAAAAAAATCCTTAG

Upstream 100 bases:

>100_bases
TAGGCAAATTAGACCGCTTGCGACAATTATTTGTTAGAATATCGCTACTTATTTCCCTCTTATTTCGAGCTAAGAGGATT
TTCTATTTAGGAAAATAACC

Downstream 100 bases:

>100_bases
AGCGGAAAGAGTAATCAAGCGATTGATTACTCTTTATTTTTACCCTTTTAAACGGAATCGTCCCCGACTGTAACGAGTTT
TCATCAAAGCGAGGATTTGT

Product: putative zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MRIILTSLVLFAASTTSYAEKSEPIQGQLENGLRYTLLPLHSEKGRIEIRMKVNAGAIDETDTQLGATNVLKHLVLRGTK
AHPNGLTPYLNEQKWKPENNYRIESGYDHTTYHMIPPSTSNLDKSLYLLEQMLFQAKLTQEDLDDERKHILEEWRQAQSV
GRLMNQKRIAAVRTDSRYADRAIIGTAENIQNLPATQLQQFYQTWYTPNNMQLLVVGDIEPEAAQQQIQQRFSSFTAKEM
PKRDYLEPKLSEGLAINKLQDARSSVSQVAYIFRFDEMKHRVRTNEARYERLIDRLALALLSQRLQDQSAALPKGVSAIT
VRKSDIGRNTAALGWFATVASTQHELGLKQIFSEIEHLKGSPITEEELTKQKEAVQIQIENAKKDENDRDFQQWLQIMSE
SVLADKPYLTQKKLAELLEPMLKKVSAKEVNERIQQWIGSKDRLINYQPPRKVQIKPITLETVNKLQAEAEQTELAKTEA
EKTEVEKAEVEKTEATQPATEKNP

Sequences:

>Translated_504_residues
MRIILTSLVLFAASTTSYAEKSEPIQGQLENGLRYTLLPLHSEKGRIEIRMKVNAGAIDETDTQLGATNVLKHLVLRGTK
AHPNGLTPYLNEQKWKPENNYRIESGYDHTTYHMIPPSTSNLDKSLYLLEQMLFQAKLTQEDLDDERKHILEEWRQAQSV
GRLMNQKRIAAVRTDSRYADRAIIGTAENIQNLPATQLQQFYQTWYTPNNMQLLVVGDIEPEAAQQQIQQRFSSFTAKEM
PKRDYLEPKLSEGLAINKLQDARSSVSQVAYIFRFDEMKHRVRTNEARYERLIDRLALALLSQRLQDQSAALPKGVSAIT
VRKSDIGRNTAALGWFATVASTQHELGLKQIFSEIEHLKGSPITEEELTKQKEAVQIQIENAKKDENDRDFQQWLQIMSE
SVLADKPYLTQKKLAELLEPMLKKVSAKEVNERIQQWIGSKDRLINYQPPRKVQIKPITLETVNKLQAEAEQTELAKTEA
EKTEVEKAEVEKTEATQPATEKNP
>Mature_504_residues
MRIILTSLVLFAASTTSYAEKSEPIQGQLENGLRYTLLPLHSEKGRIEIRMKVNAGAIDETDTQLGATNVLKHLVLRGTK
AHPNGLTPYLNEQKWKPENNYRIESGYDHTTYHMIPPSTSNLDKSLYLLEQMLFQAKLTQEDLDDERKHILEEWRQAQSV
GRLMNQKRIAAVRTDSRYADRAIIGTAENIQNLPATQLQQFYQTWYTPNNMQLLVVGDIEPEAAQQQIQQRFSSFTAKEM
PKRDYLEPKLSEGLAINKLQDARSSVSQVAYIFRFDEMKHRVRTNEARYERLIDRLALALLSQRLQDQSAALPKGVSAIT
VRKSDIGRNTAALGWFATVASTQHELGLKQIFSEIEHLKGSPITEEELTKQKEAVQIQIENAKKDENDRDFQQWLQIMSE
SVLADKPYLTQKKLAELLEPMLKKVSAKEVNERIQQWIGSKDRLINYQPPRKVQIKPITLETVNKLQAEAEQTELAKTEA
EKTEVEKAEVEKTEATQPATEKNP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Escherichia coli, GI1787770, Length=450, Percent_Identity=25.1111111111111, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789946, Length=256, Percent_Identity=24.609375, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 57664; Mature: 57664

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILTSLVLFAASTTSYAEKSEPIQGQLENGLRYTLLPLHSEKGRIEIRMKVNAGAIDE
CHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCEEEEEEEECCCCCCC
TDTQLGATNVLKHLVLRGTKAHPNGLTPYLNEQKWKPENNYRIESGYDHTTYHMIPPSTS
CHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCC
NLDKSLYLLEQMLFQAKLTQEDLDDERKHILEEWRQAQSVGRLMNQKRIAAVRTDSRYAD
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHC
RAIIGTAENIQNLPATQLQQFYQTWYTPNNMQLLVVGDIEPEAAQQQIQQRFSSFTAKEM
HHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHC
PKRDYLEPKLSEGLAINKLQDARSSVSQVAYIFRFDEMKHRVRTNEARYERLIDRLALAL
CCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSQRLQDQSAALPKGVSAITVRKSDIGRNTAALGWFATVASTQHELGLKQIFSEIEHLKG
HHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPITEEELTKQKEAVQIQIENAKKDENDRDFQQWLQIMSESVLADKPYLTQKKLAELLEP
CCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MLKKVSAKEVNERIQQWIGSKDRLINYQPPRKVQIKPITLETVNKLQAEAEQTELAKTEA
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
EKTEVEKAEVEKTEATQPATEKNP
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRIILTSLVLFAASTTSYAEKSEPIQGQLENGLRYTLLPLHSEKGRIEIRMKVNAGAIDE
CHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCEEEEEEEECCCCCCC
TDTQLGATNVLKHLVLRGTKAHPNGLTPYLNEQKWKPENNYRIESGYDHTTYHMIPPSTS
CHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCC
NLDKSLYLLEQMLFQAKLTQEDLDDERKHILEEWRQAQSVGRLMNQKRIAAVRTDSRYAD
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHC
RAIIGTAENIQNLPATQLQQFYQTWYTPNNMQLLVVGDIEPEAAQQQIQQRFSSFTAKEM
HHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHC
PKRDYLEPKLSEGLAINKLQDARSSVSQVAYIFRFDEMKHRVRTNEARYERLIDRLALAL
CCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSQRLQDQSAALPKGVSAITVRKSDIGRNTAALGWFATVASTQHELGLKQIFSEIEHLKG
HHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPITEEELTKQKEAVQIQIENAKKDENDRDFQQWLQIMSESVLADKPYLTQKKLAELLEP
CCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MLKKVSAKEVNERIQQWIGSKDRLINYQPPRKVQIKPITLETVNKLQAEAEQTELAKTEA
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
EKTEVEKAEVEKTEATQPATEKNP
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]