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The map label for this gene is pabB [C]

Identifier: 126208615

GI number: 126208615

Start: 1320593

End: 1321561

Strand: Reverse

Name: pabB [C]

Synonym: APL_1145

Alternate gene names: 126208615

Gene position: 1321561-1320593 (Counterclockwise)

Preceding gene: 126208624

Following gene: 126208614

Centisome position: 58.1

GC content: 39.42

Gene sequence:

>969_bases
ATGCAACATTTTATCCAAACCGCCAATCAACTCGGGCAACAGAAAAGCCCGTTTTTCTTTTTAATTGATTTTGAACGGCA
AAAACCGATGATTTGCCCGCTAGAACAAGCGGCAGCAAGCGGTCTGTTTTTCGATTTTTTTTGCAAATCGAATGTTCAAC
CACAAAACGTTAGCAAGCCGTTTGAATTTCAAATCAATCCCATTTCGTTTGAAACCTATCAGCAAGGTTTTGAGCTTGTT
CAAAAGGAAATCCAAGTCGGAAACAGTTATTTATTGAATTTGACTTATCCGACTGAAATTCAAACCAATTACAGTTTAGA
AGAACTGTTTTTCGCCAGTTCGGCAAAATATAAATTATGGCTGAAGGGGCAGTTTGTTTGTTTTTCGCCGGAAACTTTTG
TGCGGATTCAACAAAATAAAATCTATTCTTACCCGATGAAAGGCACAATCAATGCGAATGAAGCAAATGCGGCGGAAAAG
CTGATGCAATCAGATAAAGAATTTACCGAACATAATACGATTGTAGATTTGATTCGTAATGATTTGGCGTTAGTTTCACA
AAATATTCAGGTGACGAAATATCGTTATTTAGAAAAAGTGGATACCTACTGTGGTGCTATTTATCAAACCAGTTCTGAAA
TTTGCGGCGAGCTAAACGAAAATTGGCAAGCGAGTGTTGGTTCACTATTAGCTAAGCTCCTGCCGGCAGGCTCAATTAGC
GGGGCGCCGAAGGAGAAAACCGTAGAGATTATTCAACAAGCGGAAATCGAACAGCGAGGTTATTACACCGGTATTTTCGG
CTATTTTGACGGTGAAAATTTAGAGAGTGCGGTGGCGATTCGTTTTATTGAACAGAATAATGAGCGACTGCTTTTCCGTA
GCGGTGGTGGAATTACTGCAAAAAGCGTACTGAACGATGAATATAATGAACTGTTGGAGAAAGTTTATGTGCCGATTTCC
ATTGTTTGA

Upstream 100 bases:

>100_bases
GTATTATAGCAATCCGACGAAAAATGAAAAGTGAAAGAACGTTGCTAAATCGGCGGAAATTCCCCTAGAATAACGGCAAT
ATTCGTCACATTTTGAGTTT

Downstream 100 bases:

>100_bases
AACGATTGCAATTATTGATGGCGAACCGCAGAATTTAGCTTATCATCAGCAACGTTTTGAAAGTGCGATGAAGCAATATT
TTAATGCGCAACCGCAATGG

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQHFIQTANQLGQQKSPFFFLIDFERQKPMICPLEQAAASGLFFDFFCKSNVQPQNVSKPFEFQINPISFETYQQGFELV
QKEIQVGNSYLLNLTYPTEIQTNYSLEELFFASSAKYKLWLKGQFVCFSPETFVRIQQNKIYSYPMKGTINANEANAAEK
LMQSDKEFTEHNTIVDLIRNDLALVSQNIQVTKYRYLEKVDTYCGAIYQTSSEICGELNENWQASVGSLLAKLLPAGSIS
GAPKEKTVEIIQQAEIEQRGYYTGIFGYFDGENLESAVAIRFIEQNNERLLFRSGGGITAKSVLNDEYNELLEKVYVPIS
IV

Sequences:

>Translated_322_residues
MQHFIQTANQLGQQKSPFFFLIDFERQKPMICPLEQAAASGLFFDFFCKSNVQPQNVSKPFEFQINPISFETYQQGFELV
QKEIQVGNSYLLNLTYPTEIQTNYSLEELFFASSAKYKLWLKGQFVCFSPETFVRIQQNKIYSYPMKGTINANEANAAEK
LMQSDKEFTEHNTIVDLIRNDLALVSQNIQVTKYRYLEKVDTYCGAIYQTSSEICGELNENWQASVGSLLAKLLPAGSIS
GAPKEKTVEIIQQAEIEQRGYYTGIFGYFDGENLESAVAIRFIEQNNERLLFRSGGGITAKSVLNDEYNELLEKVYVPIS
IV
>Mature_322_residues
MQHFIQTANQLGQQKSPFFFLIDFERQKPMICPLEQAAASGLFFDFFCKSNVQPQNVSKPFEFQINPISFETYQQGFELV
QKEIQVGNSYLLNLTYPTEIQTNYSLEELFFASSAKYKLWLKGQFVCFSPETFVRIQQNKIYSYPMKGTINANEANAAEK
LMQSDKEFTEHNTIVDLIRNDLALVSQNIQVTKYRYLEKVDTYCGAIYQTSSEICGELNENWQASVGSLLAKLLPAGSIS
GAPKEKTVEIIQQAEIEQRGYYTGIFGYFDGENLESAVAIRFIEQNNERLLFRSGGGITAKSVLNDEYNELLEKVYVPIS
IV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=272, Percent_Identity=31.6176470588235, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787518, Length=273, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=202, Percent_Identity=29.2079207920792, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324361, Length=311, Percent_Identity=26.0450160771704, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: 6.3.5.8

Molecular weight: Translated: 36723; Mature: 36723

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHFIQTANQLGQQKSPFFFLIDFERQKPMICPLEQAAASGLFFDFFCKSNVQPQNVSKP
CCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCC
FEFQINPISFETYQQGFELVQKEIQVGNSYLLNLTYPTEIQTNYSLEELFFASSAKYKLW
CEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEE
LKGQFVCFSPETFVRIQQNKIYSYPMKGTINANEANAAEKLMQSDKEFTEHNTIVDLIRN
EEEEEEEECCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLALVSQNIQVTKYRYLEKVDTYCGAIYQTSSEICGELNENWQASVGSLLAKLLPAGSIS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
GAPKEKTVEIIQQAEIEQRGYYTGIFGYFDGENLESAVAIRFIEQNNERLLFRSGGGITA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCEEH
KSVLNDEYNELLEKVYVPISIV
HHHHCHHHHHHHHHHHCCEEEC
>Mature Secondary Structure
MQHFIQTANQLGQQKSPFFFLIDFERQKPMICPLEQAAASGLFFDFFCKSNVQPQNVSKP
CCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCC
FEFQINPISFETYQQGFELVQKEIQVGNSYLLNLTYPTEIQTNYSLEELFFASSAKYKLW
CEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEE
LKGQFVCFSPETFVRIQQNKIYSYPMKGTINANEANAAEKLMQSDKEFTEHNTIVDLIRN
EEEEEEEECCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLALVSQNIQVTKYRYLEKVDTYCGAIYQTSSEICGELNENWQASVGSLLAKLLPAGSIS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
GAPKEKTVEIIQQAEIEQRGYYTGIFGYFDGENLESAVAIRFIEQNNERLLFRSGGGITA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCEEH
KSVLNDEYNELLEKVYVPISIV
HHHHCHHHHHHHHHHHCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]