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The map label for this gene is focA [H]

Identifier: 126208511

GI number: 126208511

Start: 1205337

End: 1206161

Strand: Reverse

Name: focA [H]

Synonym: APL_1037

Alternate gene names: 126208511

Gene position: 1206161-1205337 (Counterclockwise)

Preceding gene: 126208513

Following gene: 126208510

Centisome position: 53.03

GC content: 40.85

Gene sequence:

>825_bases
ATGTTCTCTCCTGCTGAAATGGCAAAAATCGCTGAAGACGGCGCAGTTTATAAAGCGACTAAACATCAATTATATTCTTT
CATCTCCGCAATTTTAGCAGGTGGCTTTATTGGACTTGCATTCGTATTTTATACCACAACCCAAACCGGTGCGGTCGATG
TGCCTTGGGGTATGGCAAAATTGGTCGGTGGTACGGTTTTCTCACTCGGCGTAATTTTATGTGTGGTATTCGGTGCTGAA
CTTTTTACTTCATCAACTTTAACCGCTGTGGCTAAAGCGACGCATCGTATTACTTGGTTTCAAATGTTTAAAAACTGGTG
CATTGTGTACGGCGGTAATTTTATCGGCGGTTTGAGTGTAGTAGTGTTGATTTGGCTCTCCGGTCAAATTATGGCGGCAA
ACGGTCAATGGGGTTTAACTATTCTTAAAACGGCACAACATAAAATTCACCATACTTGGATAGAAGCCTTTACCCTCGGT
ATTTTATGTAACATGATGGTTTGTCTTGCCGTATGGATGGCAAATGCCGGTAAAAGCCTAACCGATAAAGCGTTTATTAT
GATTATGCCGATTGCTTTGTTCGTATCGTCAGGCTTCGAGCACTGTGTTGCCAATATGTTTATGATTCCGATGGGCATGA
TGATTGCACATTTTGCCTCACCTGAATTTTGGATGGCAATTAACGTTGATTCGGCACAATTTGCAGATTTAGATTTATAT
CATTTTATTGTGAAAAATTTAATTCCGGTGACATTCGGTAATATTGTCGGCGGGGTATTTTTCATCGGCTTAGTGCAGTG
GTTCTTATATATCCGTAAGCACTAA

Upstream 100 bases:

>100_bases
CCTCAATATAATTACAATTTTGTTTTGAGGGATTGAGGTAACAGGTCTATAATTCTCAACAATTTCTGTAATTTTTCAAA
TTTATATTTAAGGATTATAA

Downstream 100 bases:

>100_bases
CATAATTTCAATTTAAGCGGTTTTATTTGGGGAGTTTTTTGCAAAAATGACCGCTTGTACAGCTTAATTTACTAACAAAT
AGAGGACTTAAAATGACTCA

Product: putative formate transporter

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MFSPAEMAKIAEDGAVYKATKHQLYSFISAILAGGFIGLAFVFYTTTQTGAVDVPWGMAKLVGGTVFSLGVILCVVFGAE
LFTSSTLTAVAKATHRITWFQMFKNWCIVYGGNFIGGLSVVVLIWLSGQIMAANGQWGLTILKTAQHKIHHTWIEAFTLG
ILCNMMVCLAVWMANAGKSLTDKAFIMIMPIALFVSSGFEHCVANMFMIPMGMMIAHFASPEFWMAINVDSAQFADLDLY
HFIVKNLIPVTFGNIVGGVFFIGLVQWFLYIRKH

Sequences:

>Translated_274_residues
MFSPAEMAKIAEDGAVYKATKHQLYSFISAILAGGFIGLAFVFYTTTQTGAVDVPWGMAKLVGGTVFSLGVILCVVFGAE
LFTSSTLTAVAKATHRITWFQMFKNWCIVYGGNFIGGLSVVVLIWLSGQIMAANGQWGLTILKTAQHKIHHTWIEAFTLG
ILCNMMVCLAVWMANAGKSLTDKAFIMIMPIALFVSSGFEHCVANMFMIPMGMMIAHFASPEFWMAINVDSAQFADLDLY
HFIVKNLIPVTFGNIVGGVFFIGLVQWFLYIRKH
>Mature_274_residues
MFSPAEMAKIAEDGAVYKATKHQLYSFISAILAGGFIGLAFVFYTTTQTGAVDVPWGMAKLVGGTVFSLGVILCVVFGAE
LFTSSTLTAVAKATHRITWFQMFKNWCIVYGGNFIGGLSVVVLIWLSGQIMAANGQWGLTILKTAQHKIHHTWIEAFTLG
ILCNMMVCLAVWMANAGKSLTDKAFIMIMPIALFVSSGFEHCVANMFMIPMGMMIAHFASPEFWMAINVDSAQFADLDLY
HFIVKNLIPVTFGNIVGGVFFIGLVQWFLYIRKH

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=271, Percent_Identity=61.6236162361624, Blast_Score=345, Evalue=1e-96,
Organism=Escherichia coli, GI1788837, Length=272, Percent_Identity=43.3823529411765, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI87082249, Length=271, Percent_Identity=29.1512915129151, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321779, Length=217, Percent_Identity=29.9539170506912, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 30154; Mature: 30154

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPAEMAKIAEDGAVYKATKHQLYSFISAILAGGFIGLAFVFYTTTQTGAVDVPWGMAK
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHH
LVGGTVFSLGVILCVVFGAELFTSSTLTAVAKATHRITWFQMFKNWCIVYGGNFIGGLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHH
VVLIWLSGQIMAANGQWGLTILKTAQHKIHHTWIEAFTLGILCNMMVCLAVWMANAGKSL
HHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TDKAFIMIMPIALFVSSGFEHCVANMFMIPMGMMIAHFASPEFWMAINVDSAQFADLDLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
HFIVKNLIPVTFGNIVGGVFFIGLVQWFLYIRKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSPAEMAKIAEDGAVYKATKHQLYSFISAILAGGFIGLAFVFYTTTQTGAVDVPWGMAK
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHH
LVGGTVFSLGVILCVVFGAELFTSSTLTAVAKATHRITWFQMFKNWCIVYGGNFIGGLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHH
VVLIWLSGQIMAANGQWGLTILKTAQHKIHHTWIEAFTLGILCNMMVCLAVWMANAGKSL
HHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TDKAFIMIMPIALFVSSGFEHCVANMFMIPMGMMIAHFASPEFWMAINVDSAQFADLDLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
HFIVKNLIPVTFGNIVGGVFFIGLVQWFLYIRKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]