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The map label for this gene is pheA [H]

Identifier: 126208507

GI number: 126208507

Start: 1198612

End: 1199769

Strand: Reverse

Name: pheA [H]

Synonym: APL_1033

Alternate gene names: 126208507

Gene position: 1199769-1198612 (Counterclockwise)

Preceding gene: 126208508

Following gene: 126208506

Centisome position: 52.75

GC content: 41.02

Gene sequence:

>1158_bases
ATGTCTTTAGATTTATCCGATATCCGCCAACAAATTACCCAACTTGACCGCCATTTACTCAAATTACTTGCCGAGCGTCA
TCGTCTCGCTTTTGATGTGGTGCGTAGCAAAGAAATCACACAAAAGCCGTTACGTGATATCGAACGGGAAAAAGCGTTAT
TACAAGCATTGGTGAGCCATGCCGAAGCGGAAAATTATCAATTAGATCCGCAATATGTCACACAAATATTCCAGCGTATT
ATCGAAGATTCGGTGCTGACTCAGCAAAATTATCTGCAAAATAAATTAAATGCGCAAAAAGAACAAAATGTATCGATTGC
CTTCCTAGGTATGCGCGGTTCTTATTCCAATATGGCGTCTCGTCAATTTGCGAAAAAATATCAAGGTTCTTTAATTGAAT
TGAGCTGTGATTCGTTCCAACAAGTGTTTGATAAGGTGAGTGGGGGTGAAGCCGAATTCGGTGTACTTCCGCTTGAAAAC
ACCACTTCTGGTTCAATCAATGACGTATATGATTTACTGCAACATACCGATTTGGCGGTGGTCGGCGAATTGGCTTATCC
GATTAAACATTGCGTATTGGCAAACGGTAATATTGAGCTTACTGAAATTGATACTTTGTACAGCCACCCGCAAGTCATCC
AACAATGCAGCCAGTTTATTCAAAGTCTGAATAAAGTCCATATCAAATATTGTGAAAGCAGCTCGCACGCCATGCAGATG
GTCGCTCGTTTGAATAAGCCGAATATTGTCGCATTAGGCAATGAGGACGGCGGAAAGCTTTACGGTTTAACTAATATCAA
AACCGATATTGCCAACCAACAGAATAATATCACGCGCTTTATCGTAGTAGCAAAACAAGCGATTAACGTTTCGCCGCAGC
TACAAACAAAAACGTTATTACTGATGACCACATCTCAACAAGCCGGTGCGTTAGCGGATGCGTTGATGGTCTTTAAACAG
CATCAAATCCGCATGACCAAATTGGAATCTCGTCCGATTTACGGTAAGCCTTGGGAAGAGATGTTCTATATAGAATTACA
AGCGAATATTCATTCCGAAAATACGCAACAAGCGTTAAAAGCATTGGAAAACGTAACCAGCTATATCAAAGTATTAGGCT
GTTACCCGAGTGAAATTATTGAGCCGGTAAAGCTGTAA

Upstream 100 bases:

>100_bases
GTCAAATTTGCAAAAAATCTTGCAAATTCGACCGCTTATCTTTTTTTTATCGACTAAATCGCTATAATCTTGATAAATCA
AATAATTAAGAGAAAACACA

Downstream 100 bases:

>100_bases
CAAGCGGTTAAATTTTAAGATTTTTTTGCAAAACCCCAAAGGGCAATAGATAATAAGCTATTGTCCTTTCGTTTTTTATT
GATTATGTCGAAGCTAGTTA

Product: P-protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSLDLSDIRQQITQLDRHLLKLLAERHRLAFDVVRSKEITQKPLRDIEREKALLQALVSHAEAENYQLDPQYVTQIFQRI
IEDSVLTQQNYLQNKLNAQKEQNVSIAFLGMRGSYSNMASRQFAKKYQGSLIELSCDSFQQVFDKVSGGEAEFGVLPLEN
TTSGSINDVYDLLQHTDLAVVGELAYPIKHCVLANGNIELTEIDTLYSHPQVIQQCSQFIQSLNKVHIKYCESSSHAMQM
VARLNKPNIVALGNEDGGKLYGLTNIKTDIANQQNNITRFIVVAKQAINVSPQLQTKTLLLMTTSQQAGALADALMVFKQ
HQIRMTKLESRPIYGKPWEEMFYIELQANIHSENTQQALKALENVTSYIKVLGCYPSEIIEPVKL

Sequences:

>Translated_385_residues
MSLDLSDIRQQITQLDRHLLKLLAERHRLAFDVVRSKEITQKPLRDIEREKALLQALVSHAEAENYQLDPQYVTQIFQRI
IEDSVLTQQNYLQNKLNAQKEQNVSIAFLGMRGSYSNMASRQFAKKYQGSLIELSCDSFQQVFDKVSGGEAEFGVLPLEN
TTSGSINDVYDLLQHTDLAVVGELAYPIKHCVLANGNIELTEIDTLYSHPQVIQQCSQFIQSLNKVHIKYCESSSHAMQM
VARLNKPNIVALGNEDGGKLYGLTNIKTDIANQQNNITRFIVVAKQAINVSPQLQTKTLLLMTTSQQAGALADALMVFKQ
HQIRMTKLESRPIYGKPWEEMFYIELQANIHSENTQQALKALENVTSYIKVLGCYPSEIIEPVKL
>Mature_384_residues
SLDLSDIRQQITQLDRHLLKLLAERHRLAFDVVRSKEITQKPLRDIEREKALLQALVSHAEAENYQLDPQYVTQIFQRII
EDSVLTQQNYLQNKLNAQKEQNVSIAFLGMRGSYSNMASRQFAKKYQGSLIELSCDSFQQVFDKVSGGEAEFGVLPLENT
TSGSINDVYDLLQHTDLAVVGELAYPIKHCVLANGNIELTEIDTLYSHPQVIQQCSQFIQSLNKVHIKYCESSSHAMQMV
ARLNKPNIVALGNEDGGKLYGLTNIKTDIANQQNNITRFIVVAKQAINVSPQLQTKTLLLMTTSQQAGALADALMVFKQH
QIRMTKLESRPIYGKPWEEMFYIELQANIHSENTQQALKALENVTSYIKVLGCYPSEIIEPVKL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=376, Percent_Identity=51.5957446808511, Blast_Score=410, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6324013, Length=326, Percent_Identity=24.2331288343558, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 43556; Mature: 43425

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLSDIRQQITQLDRHLLKLLAERHRLAFDVVRSKEITQKPLRDIEREKALLQALVSH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAENYQLDPQYVTQIFQRIIEDSVLTQQNYLQNKLNAQKEQNVSIAFLGMRGSYSNMAS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCHHHHHH
RQFAKKYQGSLIELSCDSFQQVFDKVSGGEAEFGVLPLENTTSGSINDVYDLLQHTDLAV
HHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHH
VGELAYPIKHCVLANGNIELTEIDTLYSHPQVIQQCSQFIQSLNKVHIKYCESSSHAMQM
HHHHHHHHHHHEEECCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VARLNKPNIVALGNEDGGKLYGLTNIKTDIANQQNNITRFIVVAKQAINVSPQLQTKTLL
HHHCCCCCEEEECCCCCCEEEEECCCHHHHCCCCCCCEEEEEEEHHHHCCCCCCCCEEEE
LMTTSQQAGALADALMVFKQHQIRMTKLESRPIYGKPWEEMFYIELQANIHSENTQQALK
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHH
ALENVTSYIKVLGCYPSEIIEPVKL
HHHHHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure 
SLDLSDIRQQITQLDRHLLKLLAERHRLAFDVVRSKEITQKPLRDIEREKALLQALVSH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAENYQLDPQYVTQIFQRIIEDSVLTQQNYLQNKLNAQKEQNVSIAFLGMRGSYSNMAS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCHHHHHH
RQFAKKYQGSLIELSCDSFQQVFDKVSGGEAEFGVLPLENTTSGSINDVYDLLQHTDLAV
HHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHH
VGELAYPIKHCVLANGNIELTEIDTLYSHPQVIQQCSQFIQSLNKVHIKYCESSSHAMQM
HHHHHHHHHHHEEECCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VARLNKPNIVALGNEDGGKLYGLTNIKTDIANQQNNITRFIVVAKQAINVSPQLQTKTLL
HHHCCCCCEEEECCCCCCEEEEECCCHHHHCCCCCCCEEEEEEEHHHHCCCCCCCCEEEE
LMTTSQQAGALADALMVFKQHQIRMTKLESRPIYGKPWEEMFYIELQANIHSENTQQALK
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHH
ALENVTSYIKVLGCYPSEIIEPVKL
HHHHHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]