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The map label for this gene is yeiJ [C]

Identifier: 126208490

GI number: 126208490

Start: 1181936

End: 1183204

Strand: Reverse

Name: yeiJ [C]

Synonym: APL_1016

Alternate gene names: 126208490

Gene position: 1183204-1181936 (Counterclockwise)

Preceding gene: 126208492

Following gene: 126208489

Centisome position: 52.02

GC content: 45.15

Gene sequence:

>1269_bases
ATGAGTGCGTTAAATAGTATCTTAGGTATTGTCGTACTGCTACTGATTGCCTTTGTATTATCAAATAATCGTAAAGCAAT
CAGTTTCCGTACGGTAATCGGAGCGTTAGTTCTACAAGTCGGTATCGGTGCGATCATCCTTTATTGGGAAACGGGTCGTA
AAGGTTTATTAGCGGCAGCGGAAGGTGTGAGTAAAGTTATCAGCTACGGTAACGACGGTATCAGCTTCTTATTCGGCGGC
TTGGTCAGCGACAAAATGTTTGAAGTGTTCGGCGGCGGCGGTTTCGTTTTCGCATTAAAAGTGCTTCCTCCGATTATCTT
CTTCTCTGCGCTTATTTCCGTTCTTTACTATTTAGGTATCATGCAGATTGTGATTCGAATCCTCGGCGGTGCGTTACAAA
AAGTATTAGGCACGTCAAAATCAGAATCGATGTCTGCGGCGGCGAATATTTTCGTCGGTCAAACAGAAGCGCCTCTTTTA
GTTAAACCTTACATTAAATCAATGACTAACTCCGAGTTATTCGCGGTAATGTGCGGCGGTTTAGCCTCGGTTGCCGGTGC
GGTAATGATTGGTTATGCAGGTATGGGCGTACCGCTTCCGTATTTAATTGCCGCATCGTTTATGGCGGCGCCGGGCGGTT
TGTTATTCGCTAAAATTCTTCATCCGCAATCGGAACAATTTAAAGACGAATTAAGCGATGACGACATTGAAGAAAAACCT
TCGAATGTCATTGAAGCGGCGGCAGTCGGTGCCTTCTCCGGTATGCAATTGGCAATGAACGTCGGTGCAATGTTATTAGC
GTTTATCGCATTGATCGCAATGCTTAACGGCTTTATCGGCGGCGTATCTTCATTTATCGGTTATGAAAACGTAACGTTAC
AATCATTATTCGGTTATGTATTCCAACCTTTAGCATGGCTAATCGGTGTGCCTTGGGGAGCCGAATCGCAAGTAGCCGGT
TCGTTAATCGGTCAGAAATTAATTTTAAATGAATTCGTTGCTTATGCCGATTTCGTGAATTACTTAAAACCGGAAGCGGC
GGTTGCGTTAAGTCCGAAAACAATCGCTATCATCACTTTCTCACTATGTGGTTTTGCAAACTTAAGCTCAATCGCAATCT
TAATCGGCGGTTTAGGCGGTATGGCGCCAAGTCGTCGTAGCGACGTAGCGCGTATGGGTGTGAAAGCTGTTGTTGCAGGT
ACGCTCTCCAACTTAATGAGTGCGGCGATTGCCGGTTTATTTATCGGTATCGGCGGCGCGGTAATGTAA

Upstream 100 bases:

>100_bases
GATTTTTTGTGTAAAAAAAGGTATAGTTATGAAACTTTTTTAGATGGCGTTTTTTTAGGAAAACGACGTATTATTCCTTT
TCTTTTTGAGGTTTTTTCAA

Downstream 100 bases:

>100_bases
TCGCAATTGATTTATAGAAACACCACTGGAAACAGTGGTGTTGTCGTTTTAGAGCTAAGTAAACGTTTGCGCGTATGTAT
ATCGTGCAAGCGGTCTAATT

Product: putative nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSALNSILGIVVLLLIAFVLSNNRKAISFRTVIGALVLQVGIGAIILYWETGRKGLLAAAEGVSKVISYGNDGISFLFGG
LVSDKMFEVFGGGGFVFALKVLPPIIFFSALISVLYYLGIMQIVIRILGGALQKVLGTSKSESMSAAANIFVGQTEAPLL
VKPYIKSMTNSELFAVMCGGLASVAGAVMIGYAGMGVPLPYLIAASFMAAPGGLLFAKILHPQSEQFKDELSDDDIEEKP
SNVIEAAAVGAFSGMQLAMNVGAMLLAFIALIAMLNGFIGGVSSFIGYENVTLQSLFGYVFQPLAWLIGVPWGAESQVAG
SLIGQKLILNEFVAYADFVNYLKPEAAVALSPKTIAIITFSLCGFANLSSIAILIGGLGGMAPSRRSDVARMGVKAVVAG
TLSNLMSAAIAGLFIGIGGAVM

Sequences:

>Translated_422_residues
MSALNSILGIVVLLLIAFVLSNNRKAISFRTVIGALVLQVGIGAIILYWETGRKGLLAAAEGVSKVISYGNDGISFLFGG
LVSDKMFEVFGGGGFVFALKVLPPIIFFSALISVLYYLGIMQIVIRILGGALQKVLGTSKSESMSAAANIFVGQTEAPLL
VKPYIKSMTNSELFAVMCGGLASVAGAVMIGYAGMGVPLPYLIAASFMAAPGGLLFAKILHPQSEQFKDELSDDDIEEKP
SNVIEAAAVGAFSGMQLAMNVGAMLLAFIALIAMLNGFIGGVSSFIGYENVTLQSLFGYVFQPLAWLIGVPWGAESQVAG
SLIGQKLILNEFVAYADFVNYLKPEAAVALSPKTIAIITFSLCGFANLSSIAILIGGLGGMAPSRRSDVARMGVKAVVAG
TLSNLMSAAIAGLFIGIGGAVM
>Mature_421_residues
SALNSILGIVVLLLIAFVLSNNRKAISFRTVIGALVLQVGIGAIILYWETGRKGLLAAAEGVSKVISYGNDGISFLFGGL
VSDKMFEVFGGGGFVFALKVLPPIIFFSALISVLYYLGIMQIVIRILGGALQKVLGTSKSESMSAAANIFVGQTEAPLLV
KPYIKSMTNSELFAVMCGGLASVAGAVMIGYAGMGVPLPYLIAASFMAAPGGLLFAKILHPQSEQFKDELSDDDIEEKPS
NVIEAAAVGAFSGMQLAMNVGAMLLAFIALIAMLNGFIGGVSSFIGYENVTLQSLFGYVFQPLAWLIGVPWGAESQVAGS
LIGQKLILNEFVAYADFVNYLKPEAAVALSPKTIAIITFSLCGFANLSSIAILIGGLGGMAPSRRSDVARMGVKAVVAGT
LSNLMSAAIAGLFIGIGGAVM

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=430, Percent_Identity=37.6744186046512, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI227116277, Length=418, Percent_Identity=37.799043062201, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI11545853, Length=417, Percent_Identity=36.9304556354916, Blast_Score=252, Evalue=4e-67,
Organism=Escherichia coli, GI1788485, Length=418, Percent_Identity=51.4354066985646, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1788488, Length=418, Percent_Identity=52.1531100478469, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788737, Length=416, Percent_Identity=32.2115384615385, Blast_Score=191, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI71991794, Length=417, Percent_Identity=34.052757793765, Blast_Score=234, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17560276, Length=398, Percent_Identity=31.1557788944724, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI25146537, Length=232, Percent_Identity=33.1896551724138, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45552519, Length=415, Percent_Identity=37.5903614457831, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI45552517, Length=415, Percent_Identity=37.5903614457831, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI19921868, Length=415, Percent_Identity=37.5903614457831, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI281360430, Length=410, Percent_Identity=35.609756097561, Blast_Score=242, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43854; Mature: 43722

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNSILGIVVLLLIAFVLSNNRKAISFRTVIGALVLQVGIGAIILYWETGRKGLLAAA
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
EGVSKVISYGNDGISFLFGGLVSDKMFEVFGGGGFVFALKVLPPIIFFSALISVLYYLGI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQIVIRILGGALQKVLGTSKSESMSAAANIFVGQTEAPLLVKPYIKSMTNSELFAVMCGG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCCCCCEEEHHHHHCCCCCHHHHHHHHH
LASVAGAVMIGYAGMGVPLPYLIAASFMAAPGGLLFAKILHPQSEQFKDELSDDDIEEKP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCCHHCH
SNVIEAAAVGAFSGMQLAMNVGAMLLAFIALIAMLNGFIGGVSSFIGYENVTLQSLFGYV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FQPLAWLIGVPWGAESQVAGSLIGQKLILNEFVAYADFVNYLKPEAAVALSPKTIAIITF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCEEEEEEH
SLCGFANLSSIAILIGGLGGMAPSRRSDVARMGVKAVVAGTLSNLMSAAIAGLFIGIGGA
HHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VM
CC
>Mature Secondary Structure 
SALNSILGIVVLLLIAFVLSNNRKAISFRTVIGALVLQVGIGAIILYWETGRKGLLAAA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
EGVSKVISYGNDGISFLFGGLVSDKMFEVFGGGGFVFALKVLPPIIFFSALISVLYYLGI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQIVIRILGGALQKVLGTSKSESMSAAANIFVGQTEAPLLVKPYIKSMTNSELFAVMCGG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCCCCCEEEHHHHHCCCCCHHHHHHHHH
LASVAGAVMIGYAGMGVPLPYLIAASFMAAPGGLLFAKILHPQSEQFKDELSDDDIEEKP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCCHHCH
SNVIEAAAVGAFSGMQLAMNVGAMLLAFIALIAMLNGFIGGVSSFIGYENVTLQSLFGYV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FQPLAWLIGVPWGAESQVAGSLIGQKLILNEFVAYADFVNYLKPEAAVALSPKTIAIITF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCEEEEEEH
SLCGFANLSSIAILIGGLGGMAPSRRSDVARMGVKAVVAGTLSNLMSAAIAGLFIGIGGA
HHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]