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The map label for this gene is deoC

Identifier: 126208489

GI number: 126208489

Start: 1181023

End: 1181799

Strand: Reverse

Name: deoC

Synonym: APL_1015

Alternate gene names: 126208489

Gene position: 1181799-1181023 (Counterclockwise)

Preceding gene: 126208490

Following gene: 126208488

Centisome position: 51.96

GC content: 44.27

Gene sequence:

>777_bases
ATGAGTTTAAAAGATTCGGCGAAAATCGCTTTATCCTTAATGGATTTAACCACATTAAATGACAACGATACGGATGAGAA
AGTTATTACGCTTTGCCAACAAGGTAAGACGGAATTCGGTACGCCGGCAGCGGTATGCGTTTACCCGCGTTTTGTGCCTA
TCGCACGTAAAGCGTTAAAAGCACAGGGAACCGAGCAAGTTAAAATTGCCACGGTAACCAATTTCCCGCATGGCAACAAT
GATATTGACATTGCAGTCGCAGAAACCAAAGCGGCGGTGGCTTACGGTGCCGATGAAGTGGATGTGGTCTTCCCTTACAA
AGCATTAATGGCGGGTAACGAACAAATCGGCTTTGAATTGGTACAACAATGTAAGGCGGTTTGCCAAGCGTCAAACGTAT
TACTAAAAGTCATTATTGAAACCGGCGAACTGAAAACTGCCGAATTAATTCGTAAAGCGAGCGAAATTTCCATTAAAGCC
GGCGCGGATTTTATTAAAACTTCAACAGGTAAAGTGCCGGTAAATGCAACGCTTGAATATGCTCGTATTATGTTAGAAAC
CATTCGTGATTTAAACGTAGCGGATAGAGTCGGCTTTAAAGCGGCGGGCGGCGTGAAAACAGCGGAAGAAGCGGCGCAAT
ATTTAGCGCTTGCGCAAGAAATTTTAGGTCATGATTGGGTGAATTCGGATCATTTCCGTTTCGGCGCTTCAAGTTTACTG
ACGAATTTACTGGCGGCATTAAACGGACAAGCAAACCAAAAAGTCAGCGGCTACTAA

Upstream 100 bases:

>100_bases
GGTGTTGTCGTTTTAGAGCTAAGTAAACGTTTGCGCGTATGTATATCGTGCAAGCGGTCTAATTTTTCTATATTTTTACA
AAAGTAAGAAGGGGGCTCGT

Downstream 100 bases:

>100_bases
GCAAGCGGTCTAAATTTATTAATTTTTTACAAACTATATCGTAATAGAGGAAAACAAAATGGCTACTCCACACATTAACG
CACCGGAAGGTGCATTTGCT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSLKDSAKIALSLMDLTTLNDNDTDEKVITLCQQGKTEFGTPAAVCVYPRFVPIARKALKAQGTEQVKIATVTNFPHGNN
DIDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFELVQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKA
GADFIKTSTGKVPVNATLEYARIMLETIRDLNVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLL
TNLLAALNGQANQKVSGY

Sequences:

>Translated_258_residues
MSLKDSAKIALSLMDLTTLNDNDTDEKVITLCQQGKTEFGTPAAVCVYPRFVPIARKALKAQGTEQVKIATVTNFPHGNN
DIDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFELVQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKA
GADFIKTSTGKVPVNATLEYARIMLETIRDLNVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLL
TNLLAALNGQANQKVSGY
>Mature_257_residues
SLKDSAKIALSLMDLTTLNDNDTDEKVITLCQQGKTEFGTPAAVCVYPRFVPIARKALKAQGTEQVKIATVTNFPHGNND
IDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFELVQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKAG
ADFIKTSTGKVPVNATLEYARIMLETIRDLNVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLLT
NLLAALNGQANQKVSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=266, Percent_Identity=36.8421052631579, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1790841, Length=233, Percent_Identity=72.9613733905579, Blast_Score=347, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17533015, Length=251, Percent_Identity=39.8406374501992, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI19922098, Length=254, Percent_Identity=36.6141732283465, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_ACTP2 (A3N123)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053714.1
- ProteinModelPortal:   A3N123
- SMR:   A3N123
- STRING:   A3N123
- GeneID:   4849634
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1015
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   ELVQQCK
- PhylomeDB:   A3N123
- ProtClustDB:   PRK05283
- BioCyc:   APLE416269:APL_1015-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27680; Mature: 27549

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: ACT_SITE 166-166 ACT_SITE 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKDSAKIALSLMDLTTLNDNDTDEKVITLCQQGKTEFGTPAAVCVYPRFVPIARKALK
CCCCCCHHHEEEEEHEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
AQGTEQVKIATVTNFPHGNNDIDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFEL
CCCCCEEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHHHCCCHHHHHHH
VQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKAGADFIKTSTGKVPVNATLEY
HHHHHHHHHHHHHHHEEEHHCCCCHHHHHHHHHHHCEEECCCHHHCCCCCCCCCCHHHHH
ARIMLETIRDLNVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLL
HHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHH
TNLLAALNGQANQKVSGY
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLKDSAKIALSLMDLTTLNDNDTDEKVITLCQQGKTEFGTPAAVCVYPRFVPIARKALK
CCCCCHHHEEEEEHEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
AQGTEQVKIATVTNFPHGNNDIDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFEL
CCCCCEEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHHHCCCHHHHHHH
VQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKAGADFIKTSTGKVPVNATLEY
HHHHHHHHHHHHHHHEEEHHCCCCHHHHHHHHHHHCEEECCCHHHCCCCCCCCCCHHHHH
ARIMLETIRDLNVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLL
HHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHH
TNLLAALNGQANQKVSGY
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA