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The map label for this gene is deoD

Identifier: 126208488

GI number: 126208488

Start: 1180242

End: 1180964

Strand: Reverse

Name: deoD

Synonym: APL_1014

Alternate gene names: 126208488

Gene position: 1180964-1180242 (Counterclockwise)

Preceding gene: 126208489

Following gene: 126208487

Centisome position: 51.92

GC content: 45.37

Gene sequence:

>723_bases
ATGGCTACTCCACACATTAACGCACCGGAAGGTGCATTTGCTGACGTTGTATTAATGCCGGGCGATCCGCTTCGTGCAAA
ATATATTGCGGAAACATTTTTAGAAGATGCGGTACAAGTAACGGACGTGCGTAATATGTTCGGCTACACCGGTACTTATA
AAGGTCGCCGTATTTCGGTCATGGGACACGGTATGGGGATTCCTTCTTGCTCAATTTATGCAAAAGAATTGATTACCGAA
TACGGTGTGAAAAAGATCATTCGCGTCGGTTCTTGCGGTGCGGTACGTCAAGATGTAAAAGTGCGTGATGTAATTATCGG
TTCGGGTGCTTGCACCGATTCAAAAGTAAACCGTATCCGTTTCCGTGACAACGATTTTGCGGCAATTTCCGACTTTGATA
TGACTTTAGCGGCGGTACAAGCGGCAAAACAAAAAGGTATTGCGGCACGTGTCGGTAACTTATTCTCTGCGGACTTATTC
TATACGCCGGATGTGGAAATGTTTGACGTAATGGAAAAATACGGCATTTTAGGCGTGGAAATGGAAGCGGCGGGCATTTA
TGCGGTAGCGGCGGAATACGGTGCAAAAGCGTTAGCGATTTGTACCGTTTCAGACCATATCCGTACCGGTGAGCAAACTT
CATCGGAAGAACGCCAATTAACCTTTAATGATATGATTACGATTGCATTAGAGTCCGTGTTAATCGGCGATAAAGCGGAA
TAA

Upstream 100 bases:

>100_bases
GCATTAAACGGACAAGCAAACCAAAAAGTCAGCGGCTACTAAGCAAGCGGTCTAAATTTATTAATTTTTTACAAACTATA
TCGTAATAGAGGAAAACAAA

Downstream 100 bases:

>100_bases
GCGGTCGATTTTCCGTATTACTTTACAAATCCTCTGAGCTGAAAAGCTCGGAGGATTTTTTTGTCTAAAAATCAGACGAA
AGCGATTGCTTTTGCACAAA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITE
YGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIRFRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLF
YTPDVEMFDVMEKYGILGVEMEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE

Sequences:

>Translated_240_residues
MATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITE
YGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIRFRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLF
YTPDVEMFDVMEKYGILGVEMEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE
>Mature_239_residues
ATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITEY
GVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIRFRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLFY
TPDVEMFDVMEKYGILGVEMEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=238, Percent_Identity=82.3529411764706, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1790265, Length=234, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_ACTP2 (A3N122)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053713.1
- ProteinModelPortal:   A3N122
- SMR:   A3N122
- STRING:   A3N122
- GeneID:   4850479
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1014
- eggNOG:   COG0813
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- PhylomeDB:   A3N122
- ProtClustDB:   PRK05819
- BioCyc:   APLE416269:APL_1014-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 26015; Mature: 25884

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISV
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEEECCCCCCCCCCEEE
FRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLFYTPDVEMFDVMEKYGILGVE
ECCCCEEEECCCHHHHHHHHHHHHCCHHHHHCCHHCCCEEECCCCHHHHHHHHHCCEEEE
MEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE
EECCCEEEEEHHCCCCEEEEEEEHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISV
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEEECCCCCCCCCCEEE
FRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLFYTPDVEMFDVMEKYGILGVE
ECCCCEEEECCCHHHHHHHHHHHHCCHHHHHCCHHCCCEEECCCCHHHHHHHHHCCEEEE
MEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE
EECCCEEEEEHHCCCCEEEEEEEHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA