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The map label for this gene is sapB [H]

Identifier: 126208271

GI number: 126208271

Start: 916202

End: 917164

Strand: Reverse

Name: sapB [H]

Synonym: APL_0795

Alternate gene names: 126208271

Gene position: 917164-916202 (Counterclockwise)

Preceding gene: 126208272

Following gene: 126208270

Centisome position: 40.32

GC content: 40.29

Gene sequence:

>963_bases
ATGTTATTGGCATTTATTCGCAAATTATTTTTAACAGCGATCACGCTGATTTTGCTGACACTAATTAGCTATAACATCTT
ACTACGCGATCCTTTGAATCATTTTGTCGATTTACAGGGAATAGAAGCTTATTTCAGTTATATTCGAGGCTTACTACAAG
GCGATTTCGGCATTAGCTATACGAACGGTGAGCCGATAGCCAATCAGATTTTAAATGTCTTTCCCGCCACCGTTTCGCTT
TGTTTGGCGGTATTGATTTTATCGCTTGTTTTAGGTTTGCCGTTAGGATTTATTTCCGCCGTATTTCGGGAGAACTTGCT
CGGAAAAACGCTCGCTATTTTAGGTTCGTTAAGTTTAGCGATCCCGGTTTTTTGGCTTGCCATCGTTGTACTTTATTATG
CTTCGAATAATCAATGGGCAATTTCCGCCGTCGGGGAGCTACATCCGATTTATGAAATATCCTCTTTAACGGGCTTCCGT
TTATTAGATATTTTCTTGGCGGATTCTCCCTATAAATTGAAAATGATGCAAAGTATGTTACATCACTTAGCGTTACCGAC
CTTAATTTTAGCCGTACCTGCGACATTAGAGGTGATTCGCTTTACCCATCAACGCGCCGAGTATGTGATGAAACAAAATT
ATATTCGAGTCGCACAAACACGGGGCTGGTCGCCTTATAAAGTATGGGTAAGACATATTTTGCCTAACACGTTACCGGCA
CTCATTCCCATGATTGCGCATAATTTAACCTTGATTTTTGCATTCTCTATGTTGGTTGAAAATATATTTAGCTGGGGCGG
TATCGGCTTGTGGTTAATCAATGCGCTGTCAGTACAAGATTATAATGCGATCTCGGCCGGAGTGGTCGCCATCGGTTTAT
TCATCTTAAGTATTGATGTGCTGGTCAGTATCATTACGACACTTTTAGATCCGTATCAGAAAAAGGATTGGTATGTTAAA
TAA

Upstream 100 bases:

>100_bases
GAATTTTATTTGTAAATCCTAAAATCGAAAATGCGAAAGTCAGTCCTTTCGGGCAAGTGCATTTATCGGAACTAAAACTC
AAACATAAAGAGAAGAAATA

Downstream 100 bases:

>100_bases
AGAAGAACCGGAACAATTTAGAGAGTCGGATTACTTGAAACAATTCTTGTTGCAACTGCGTCAAGATAAAGTCGCTTTAG
CAAGTATATATTTGTTTGCC

Product: peptide transport system permease protein SapB

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLLAFIRKLFLTAITLILLTLISYNILLRDPLNHFVDLQGIEAYFSYIRGLLQGDFGISYTNGEPIANQILNVFPATVSL
CLAVLILSLVLGLPLGFISAVFRENLLGKTLAILGSLSLAIPVFWLAIVVLYYASNNQWAISAVGELHPIYEISSLTGFR
LLDIFLADSPYKLKMMQSMLHHLALPTLILAVPATLEVIRFTHQRAEYVMKQNYIRVAQTRGWSPYKVWVRHILPNTLPA
LIPMIAHNLTLIFAFSMLVENIFSWGGIGLWLINALSVQDYNAISAGVVAIGLFILSIDVLVSIITTLLDPYQKKDWYVK

Sequences:

>Translated_320_residues
MLLAFIRKLFLTAITLILLTLISYNILLRDPLNHFVDLQGIEAYFSYIRGLLQGDFGISYTNGEPIANQILNVFPATVSL
CLAVLILSLVLGLPLGFISAVFRENLLGKTLAILGSLSLAIPVFWLAIVVLYYASNNQWAISAVGELHPIYEISSLTGFR
LLDIFLADSPYKLKMMQSMLHHLALPTLILAVPATLEVIRFTHQRAEYVMKQNYIRVAQTRGWSPYKVWVRHILPNTLPA
LIPMIAHNLTLIFAFSMLVENIFSWGGIGLWLINALSVQDYNAISAGVVAIGLFILSIDVLVSIITTLLDPYQKKDWYVK
>Mature_320_residues
MLLAFIRKLFLTAITLILLTLISYNILLRDPLNHFVDLQGIEAYFSYIRGLLQGDFGISYTNGEPIANQILNVFPATVSL
CLAVLILSLVLGLPLGFISAVFRENLLGKTLAILGSLSLAIPVFWLAIVVLYYASNNQWAISAVGELHPIYEISSLTGFR
LLDIFLADSPYKLKMMQSMLHHLALPTLILAVPATLEVIRFTHQRAEYVMKQNYIRVAQTRGWSPYKVWVRHILPNTLPA
LIPMIAHNLTLIFAFSMLVENIFSWGGIGLWLINALSVQDYNAISAGVVAIGLFILSIDVLVSIITTLLDPYQKKDWYVK

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=284, Percent_Identity=37.6760563380282, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=26.5486725663717, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787761, Length=244, Percent_Identity=29.5081967213115, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787053, Length=297, Percent_Identity=24.5791245791246, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789888, Length=273, Percent_Identity=24.5421245421245, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787497, Length=341, Percent_Identity=23.4604105571848, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35819; Mature: 35819

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAFIRKLFLTAITLILLTLISYNILLRDPLNHFVDLQGIEAYFSYIRGLLQGDFGISY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TNGEPIANQILNVFPATVSLCLAVLILSLVLGLPLGFISAVFRENLLGKTLAILGSLSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVFWLAIVVLYYASNNQWAISAVGELHPIYEISSLTGFRLLDIFLADSPYKLKMMQSML
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
HHLALPTLILAVPATLEVIRFTHQRAEYVMKQNYIRVAQTRGWSPYKVWVRHILPNTLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHH
LIPMIAHNLTLIFAFSMLVENIFSWGGIGLWLINALSVQDYNAISAGVVAIGLFILSIDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LVSIITTLLDPYQKKDWYVK
HHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure
MLLAFIRKLFLTAITLILLTLISYNILLRDPLNHFVDLQGIEAYFSYIRGLLQGDFGISY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TNGEPIANQILNVFPATVSLCLAVLILSLVLGLPLGFISAVFRENLLGKTLAILGSLSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVFWLAIVVLYYASNNQWAISAVGELHPIYEISSLTGFRLLDIFLADSPYKLKMMQSML
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
HHLALPTLILAVPATLEVIRFTHQRAEYVMKQNYIRVAQTRGWSPYKVWVRHILPNTLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHH
LIPMIAHNLTLIFAFSMLVENIFSWGGIGLWLINALSVQDYNAISAGVVAIGLFILSIDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LVSIITTLLDPYQKKDWYVK
HHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]