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The map label for this gene is sapC [H]

Identifier: 126208270

GI number: 126208270

Start: 915325

End: 916212

Strand: Reverse

Name: sapC [H]

Synonym: APL_0794

Alternate gene names: 126208270

Gene position: 916212-915325 (Counterclockwise)

Preceding gene: 126208271

Following gene: 126208269

Centisome position: 40.28

GC content: 39.19

Gene sequence:

>888_bases
ATGTTAAATAAAGAAGAACCGGAACAATTTAGAGAGTCGGATTACTTGAAACAATTCTTGTTGCAACTGCGTCAAGATAA
AGTCGCTTTAGCAAGTATATATTTGTTTGCCTTTTTGCTTTTTTTAGTCTTTTTCGGTTATGTCATTGCGCCTTATCAAG
CGGATACGCAATTTATCGGAAAAGAATTGATGCCGCCCTCTTGGGACGATAACGGGCAAATTAGCTTTTTCTTTGGCACG
GACGATTTAGGTCGAGATATTTTCAGCCGGATTCTTTATGGTTTTTACTATACGGTCGGTTCCGCATTAATTATTAGTGC
GGCGGTAGCGGTAATAGGCAGCGTAATCGGTATTTTTGCCGGAACAAGTCGAAAATCATTTTCTTTCCTAGGGCATTTAT
TCGATACCTTTTTATTTATTCCGATCCTAATTATTGCGATTGTGATCGCGACCTTAATGGAAGCCAGTTTAATCAATGCA
ATGTTAGCCATATTTTTAGCGATGCTGCCGCATTTTATTCACAAAATTTATCAAGCGGTACGGCAAGAGTTGAAGAGAGA
ATATGTGATTACCTTGCGTTTAGACGGCGCATCACGTTGGGATTTAATGAAAGAAGTGGTGTTACCGAACGTTACGCCGG
TTGCGGTAAAAGAAATTTCTCATATTTTCGTGATTGCGGTCTTGGACATCAATGCACTGAGTTTTATTGAATTAGGGGCA
AAAAGCCCGACGCCGGAATGGGGGACGATGATTAAAGATTCGGTAGAATTGATTTATATTGCACCGTGGACGGTTATTCT
ACCGGGTATGGCAACTATTTTTGTGATTCTGATTATTAGTATGTTAGGTAATAGCATTAGTCGCGTATTAGAAAAATACC
GTTATTAA

Upstream 100 bases:

>100_bases
TCGGCCGGAGTGGTCGCCATCGGTTTATTCATCTTAAGTATTGATGTGCTGGTCAGTATCATTACGACACTTTTAGATCC
GTATCAGAAAAAGGATTGGT

Downstream 100 bases:

>100_bases
CATGGAATAAAGTATGGCTCTATTAGATATTCGCCATTTAAGTATTGAAATTGACACACCGAACGGCAGAGTCAGAATGG
TTGATAATATTAATCTGACT

Product: peptide transport system permease protein SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLNKEEPEQFRESDYLKQFLLQLRQDKVALASIYLFAFLLFLVFFGYVIAPYQADTQFIGKELMPPSWDDNGQISFFFGT
DDLGRDIFSRILYGFYYTVGSALIISAAVAVIGSVIGIFAGTSRKSFSFLGHLFDTFLFIPILIIAIVIATLMEASLINA
MLAIFLAMLPHFIHKIYQAVRQELKREYVITLRLDGASRWDLMKEVVLPNVTPVAVKEISHIFVIAVLDINALSFIELGA
KSPTPEWGTMIKDSVELIYIAPWTVILPGMATIFVILIISMLGNSISRVLEKYRY

Sequences:

>Translated_295_residues
MLNKEEPEQFRESDYLKQFLLQLRQDKVALASIYLFAFLLFLVFFGYVIAPYQADTQFIGKELMPPSWDDNGQISFFFGT
DDLGRDIFSRILYGFYYTVGSALIISAAVAVIGSVIGIFAGTSRKSFSFLGHLFDTFLFIPILIIAIVIATLMEASLINA
MLAIFLAMLPHFIHKIYQAVRQELKREYVITLRLDGASRWDLMKEVVLPNVTPVAVKEISHIFVIAVLDINALSFIELGA
KSPTPEWGTMIKDSVELIYIAPWTVILPGMATIFVILIISMLGNSISRVLEKYRY
>Mature_295_residues
MLNKEEPEQFRESDYLKQFLLQLRQDKVALASIYLFAFLLFLVFFGYVIAPYQADTQFIGKELMPPSWDDNGQISFFFGT
DDLGRDIFSRILYGFYYTVGSALIISAAVAVIGSVIGIFAGTSRKSFSFLGHLFDTFLFIPILIIAIVIATLMEASLINA
MLAIFLAMLPHFIHKIYQAVRQELKREYVITLRLDGASRWDLMKEVVLPNVTPVAVKEISHIFVIAVLDINALSFIELGA
KSPTPEWGTMIKDSVELIYIAPWTVILPGMATIFVILIISMLGNSISRVLEKYRY

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=284, Percent_Identity=44.0140845070423, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=29.9295774647887, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787760, Length=296, Percent_Identity=26.6891891891892, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787054, Length=288, Percent_Identity=25.6944444444444, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789889, Length=251, Percent_Identity=26.2948207171315, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33349; Mature: 33349

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKEEPEQFRESDYLKQFLLQLRQDKVALASIYLFAFLLFLVFFGYVIAPYQADTQFIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KELMPPSWDDNGQISFFFGTDDLGRDIFSRILYGFYYTVGSALIISAAVAVIGSVIGIFA
HHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTSRKSFSFLGHLFDTFLFIPILIIAIVIATLMEASLINAMLAIFLAMLPHFIHKIYQAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQELKREYVITLRLDGASRWDLMKEVVLPNVTPVAVKEISHIFVIAVLDINALSFIELGA
HHHHHHHEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSPTPEWGTMIKDSVELIYIAPWTVILPGMATIFVILIISMLGNSISRVLEKYRY
CCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]