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The map label for this gene is sapD [H]

Identifier: 126208269

GI number: 126208269

Start: 914274

End: 915311

Strand: Reverse

Name: sapD [H]

Synonym: APL_0793

Alternate gene names: 126208269

Gene position: 915311-914274 (Counterclockwise)

Preceding gene: 126208270

Following gene: 126208268

Centisome position: 40.24

GC content: 42.77

Gene sequence:

>1038_bases
ATGGCTCTATTAGATATTCGCCATTTAAGTATTGAAATTGACACACCGAACGGCAGAGTCAGAATGGTTGATAATATTAA
TCTGACTTTAGACGAAGGCGAAATCTGCGGATTAGTCGGTGAGTCCGGCTCGGGAAAAAGTTTAATCGCTAAAGTGATTT
GCGGCGTAATGAAAGACGAATGGATTGTGACCGCCGACCGTTTTCGTTTTAATGATATTGAATTGTTAAAACTGACTCCG
ACGGAAAGACGTAAATTGGTTAGCGAACATATTTCTATGATTTTCCAAAATCCGCTGTCCGGTTTAGACCCGAGTAAGAC
GATCGGCACTCAACTTATGCAAACGATTAATTTTAAAGGTAAGTGGTGGCAATGGTTCGGTTGGAAGAAAAAGAAAGCGA
TTGAATTATTGCACCGAGTCGGGATTCGCGATCATAAGACAATGATGCAAAGCTATCCGTTCGATATTACCGAAGGCGAG
GCGCAAAAAGTGATTATTGCTATGGCGGTAGCAAATCAGCCCCGTTTATTGGTTGCGGACGAACCTACACACACGCTGGA
AGCGACCACGCAGCTACAGATTTATCGTTTGTTATCCAGTATGAATAAAAACCTCGGCACTTCAATTTTATTGGTTGCCA
ATGATATTCGTAGTATTCATAAGTGGGTCGATTCGTTTAATGTGCTTTATTGCGGACAAACGGTCGAAATTGCCGGCAAA
GAAACCATTATGGAAGAACCGTTTCATCCTTATACCTCGGTATTACTGAACAGTATTCCGGACTTTTCCCAGCCGTTGGC
GTTTAAAAGCCGTTTAAATACGTTAAAAGGCTCGGTACCGATGTTGCAAGATATGCCGATAGGCTGCCGATTAGGTCCGC
GCTGCCCGTTTGCACAGAAAAAATGCGTACAAAAGCCGCCATTGCGTAAATTCAAACAGCACGAATTTGCGTGCCATTAT
CCGATTAATTTTAGGGAGAAAAATTTCTTAAAACGAGCGGATTTTGAACCGGTCGTGGTGGCGGATAAAGCGGAATAA

Upstream 100 bases:

>100_bases
CCGGGTATGGCAACTATTTTTGTGATTCTGATTATTAGTATGTTAGGTAATAGCATTAGTCGCGTATTAGAAAAATACCG
TTATTAACATGGAATAAAGT

Downstream 100 bases:

>100_bases
TTTGATCGGGCGGTTATATTTTTTCGATTTTTTGCAAATTTTTGAGAAAACAGACCGCTTGACGTTTCAATAGGATGGTA
AAATGGCAAAGAGACAAATT

Product: peptide transport system ATP-binding protein SapD

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MALLDIRHLSIEIDTPNGRVRMVDNINLTLDEGEICGLVGESGSGKSLIAKVICGVMKDEWIVTADRFRFNDIELLKLTP
TERRKLVSEHISMIFQNPLSGLDPSKTIGTQLMQTINFKGKWWQWFGWKKKKAIELLHRVGIRDHKTMMQSYPFDITEGE
AQKVIIAMAVANQPRLLVADEPTHTLEATTQLQIYRLLSSMNKNLGTSILLVANDIRSIHKWVDSFNVLYCGQTVEIAGK
ETIMEEPFHPYTSVLLNSIPDFSQPLAFKSRLNTLKGSVPMLQDMPIGCRLGPRCPFAQKKCVQKPPLRKFKQHEFACHY
PINFREKNFLKRADFEPVVVADKAE

Sequences:

>Translated_345_residues
MALLDIRHLSIEIDTPNGRVRMVDNINLTLDEGEICGLVGESGSGKSLIAKVICGVMKDEWIVTADRFRFNDIELLKLTP
TERRKLVSEHISMIFQNPLSGLDPSKTIGTQLMQTINFKGKWWQWFGWKKKKAIELLHRVGIRDHKTMMQSYPFDITEGE
AQKVIIAMAVANQPRLLVADEPTHTLEATTQLQIYRLLSSMNKNLGTSILLVANDIRSIHKWVDSFNVLYCGQTVEIAGK
ETIMEEPFHPYTSVLLNSIPDFSQPLAFKSRLNTLKGSVPMLQDMPIGCRLGPRCPFAQKKCVQKPPLRKFKQHEFACHY
PINFREKNFLKRADFEPVVVADKAE
>Mature_344_residues
ALLDIRHLSIEIDTPNGRVRMVDNINLTLDEGEICGLVGESGSGKSLIAKVICGVMKDEWIVTADRFRFNDIELLKLTPT
ERRKLVSEHISMIFQNPLSGLDPSKTIGTQLMQTINFKGKWWQWFGWKKKKAIELLHRVGIRDHKTMMQSYPFDITEGEA
QKVIIAMAVANQPRLLVADEPTHTLEATTQLQIYRLLSSMNKNLGTSILLVANDIRSIHKWVDSFNVLYCGQTVEIAGKE
TIMEEPFHPYTSVLLNSIPDFSQPLAFKSRLNTLKGSVPMLQDMPIGCRLGPRCPFAQKKCVQKPPLRKFKQHEFACHYP
INFREKNFLKRADFEPVVVADKAE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=59.0909090909091, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789963, Length=325, Percent_Identity=37.5384615384615, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI48994883, Length=322, Percent_Identity=34.7826086956522, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787759, Length=322, Percent_Identity=33.8509316770186, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787500, Length=327, Percent_Identity=30.8868501529052, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI145693107, Length=293, Percent_Identity=29.3515358361775, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789962, Length=305, Percent_Identity=27.5409836065574, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788506, Length=265, Percent_Identity=33.2075471698113, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787758, Length=283, Percent_Identity=29.6819787985866, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789890, Length=255, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994997, Length=235, Percent_Identity=25.9574468085106, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=28.7671232876712, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786398, Length=267, Percent_Identity=26.9662921348315, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787547, Length=265, Percent_Identity=26.4150943396226, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081834, Length=201, Percent_Identity=30.8457711442786, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789032, Length=247, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081791, Length=266, Percent_Identity=24.812030075188, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=24.8979591836735, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786703, Length=224, Percent_Identity=25.8928571428571, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788450, Length=236, Percent_Identity=25.4237288135593, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082267, Length=242, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790544, Length=239, Percent_Identity=25.1046025104602, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=249, Percent_Identity=26.5060240963855, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=307, Percent_Identity=23.1270358306189, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=25.4310344827586, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787105, Length=219, Percent_Identity=25.5707762557078, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=27.9816513761468, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787712, Length=265, Percent_Identity=23.7735849056604, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788225, Length=238, Percent_Identity=24.3697478991597, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 39292; Mature: 39161

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDIRHLSIEIDTPNGRVRMVDNINLTLDEGEICGLVGESGSGKSLIAKVICGVMKDE
CCEEEEEEEEEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCC
WIVTADRFRFNDIELLKLTPTERRKLVSEHISMIFQNPLSGLDPSKTIGTQLMQTINFKG
EEEEECCEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
KWWQWFGWKKKKAIELLHRVGIRDHKTMMQSYPFDITEGEAQKVIIAMAVANQPRLLVAD
CEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEC
EPTHTLEATTQLQIYRLLSSMNKNLGTSILLVANDIRSIHKWVDSFNVLYCGQTVEIAGK
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCEEEECCEEEECCC
ETIMEEPFHPYTSVLLNSIPDFSQPLAFKSRLNTLKGSVPMLQDMPIGCRLGPRCPFAQK
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHH
KCVQKPPLRKFKQHEFACHYPINFREKNFLKRADFEPVVVADKAE
HHCCCCCHHHHHCCCEEEECCCCCCHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure 
ALLDIRHLSIEIDTPNGRVRMVDNINLTLDEGEICGLVGESGSGKSLIAKVICGVMKDE
CEEEEEEEEEEEECCCCCEEEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCC
WIVTADRFRFNDIELLKLTPTERRKLVSEHISMIFQNPLSGLDPSKTIGTQLMQTINFKG
EEEEECCEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
KWWQWFGWKKKKAIELLHRVGIRDHKTMMQSYPFDITEGEAQKVIIAMAVANQPRLLVAD
CEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEC
EPTHTLEATTQLQIYRLLSSMNKNLGTSILLVANDIRSIHKWVDSFNVLYCGQTVEIAGK
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCEEEECCEEEECCC
ETIMEEPFHPYTSVLLNSIPDFSQPLAFKSRLNTLKGSVPMLQDMPIGCRLGPRCPFAQK
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHH
KCVQKPPLRKFKQHEFACHYPINFREKNFLKRADFEPVVVADKAE
HHCCCCCHHHHHCCCEEEECCCCCCHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]