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The map label for this gene is pheT [H]

Identifier: 126208091

GI number: 126208091

Start: 695123

End: 697510

Strand: Direct

Name: pheT [H]

Synonym: APL_0609

Alternate gene names: 126208091

Gene position: 695123-697510 (Clockwise)

Preceding gene: 126208090

Following gene: 126208092

Centisome position: 30.56

GC content: 43.55

Gene sequence:

>2388_bases
ATGAAATTTAATGAATCTTGGTTGCGTGAGTGGGTAAATCCTGCAGTATCAACAGAGCAATTATGCGACCAAATCACCAT
GTTAGGTTTAGAAGTCGATGATGTTGAGCCGGTTGCCGGCGCATTTAGCGGTGTGGTTGTCGGTGAAGTGGTTGAATGTG
CTCAACACCCGGATGCGGATAAATTACGTGTCACTAAAGTTAATGTTGGTGGCGATCGCTTATTAGATATCGTATGCGGT
GCGCCAAACTGTCGTCAGGGCTTAAAAGTGGCGTGTGCAACGGAAGGCGCGGTATTACCGGGCGATTTTAAAATTAAGAA
AACTAAATTACGTGGCCAACCGTCAGAAGGTATGCTTTGTTCATATTCTGAATTAGGTATCAAAGAAGATCATAGCGGTA
TCATCGAATTACCGGCGGATGCGCCAATTGGTAAAGATTTTCGTGAATATTTAGATTTAAATGATGTGGCTATCGAAATC
AGCTTAACGCCAAACCGTGCGGACTGTTTAAGTATTGCCGGTATTGCACGTGAAGTAGGTGTAATTAACCGAGCGGAAGT
GAAAGCACCGGTGATTTCAGAGGTACCCGCAACGATTGCGGATAAAGTAGCCGTAGAATTACAAGCACCGGAAGCTTGCC
CTCGTTATCTTGCTCGTGTGGTGAAAAATGTAAACGTAAAAGCAACTTCGCCATTATGGTTACAAGAAAAATTACGCCGT
TGCGGTATTCGTTCGATTGACCCGATTGTCGATATTACTAACTTAAGCCTGTTAGAACTTGGTCAACCTATGCACGCTTT
CGATGCGTCTAAAATTGACGGTGCTATCCAAGTACGTATGGCAAAAGAGGGTGAGGAATTAGTTTTATTAGACGGTACAA
CCGCAAAATTACAGCCAAATACTTTAGTCATTGCCGATAGCAAAGGCGCATTAGCAATGGCGGGTATCTTTGGCGGCGAA
GCAAGCGGTGTAAATGAAAATACGACTGACGTAGTATTAGAATCCGCATTCTTTGCACCGTTAGCGATTACCGGTCGTGC
ACGTCAATACGGTTTACACACCGATGCGTCGCACCGTTTTGAACGTGGTGTTGATCCGCAATTAGCACGTGATGCGATGG
AACGTGCAACTGCATTATTACTTGAAATTTGTGGCGGTGAAGCGGGTGAAATCGTAGAAGCAGTAAGTGAACAACATTTA
CCAAAACGTAATACGGTTACCTTACGTCGTAGCAAATTAGATGCGGTAATCGGTCATCACATTGAAGATGAAACGGTAAC
CGATATTTTAACTCGCTTAGGTTTAAACGTAATCTTTGCAAATGATAGTTGGACTGCAGTAGCCCCAAGCTGGCGTTTCG
ATATTGAGATCGAAGAAGATCTTATCGAAGAGGTTGCACGTATCTACGGTTATAACAGTATTCCGAATAATTCTCCGCTT
GCGCACTTAACGATGAAAGGCACACCGGAGAAATTATTAGAAGTAAACCGTATTCGTACTGCATTAGTGGATAGCGACTA
TCAAGAAGTGGTGACATACAGCTTTGTTGATCCGAAAAAACAAGCATTATTGCATCCGAATCAAGAAGCGTTAATTTTAC
CTAACCCGATTTCAAACGAAATGTCGGCAATGCGTTTATCACTTTTAACCGGTTTATTAGATACGATTGCTTACAACCAA
AGCCGTCAGCAAACACGTGTTCGTATTTTTGAAGGCGGTTTACGCTTTATTCCGGATGCGGCGGCAGAATCCGGTATTCG
TCAAGAACTCGTATTCGGCGCGGCAATTGTCGGTGATAAACGTCCGGTACATTGGGAAAGTAAAGGCGAAGCGGTAGATT
TCTTCGACTTAAAAGGCGATATGGAGCGCGTATTGTCTCTAACTTCGGCTCGCCATGATTTAAAATTTGTGGCAAAACAA
TTCCCTGCATTACATCCGGGACAATCTGCAGCGATTATGTTAGACGGTAAAGAAATCGGCTTTATCGGTTCCGTTCATCC
GTCAATCGTGCAAAAACTCGGCATCAAAGGTAAACCGGTGGTATTTGAAATTCTCGGTGATGCGATTGCAAATCGTCCGG
TTCCTGCGGCAAAAGAAATTTCTAAATTCCCTGCGAATAACCGTGACATTGCGGTTGTGGTAGATGAAAATGTACCTGCC
GGAGATGTATTGGATGCGTGCCGTCACGCCGGCGGTGTAAAATTAGTTGCAGTAAACTTATTTGACGTTTATCGTGGTGC
GAATTTAGCGGCAGGTAAGAAAAGTTTAGCAATCAGTTTAACGGTTCAAGACACGGAAAAAACGCTTGAGGAAGAAGAAA
TTTCGACTGTAATTCAAGCGGTCTTAGCAGAATTGGCACAACGTTTCCAAGCATATCTAAGAGATTAG

Upstream 100 bases:

>100_bases
AATAGTTAGCTACGGAAATTCACTGAATACACGGGAATGACAAGCGGTCAAAATTAAGTGGAATTTTGCAAATTCCGTGT
AAGAAAATAGAGGATATAAA

Downstream 100 bases:

>100_bases
ATTTAAGGATTATTTTTATGGCACTCACTAAAATTGAACTCGCAGAAAGCCTCGTTGAAAAATGCGGCTTTGATAAACGT
ATCGCCAAGCTCTTTGTAGA

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKFNESWLREWVNPAVSTEQLCDQITMLGLEVDDVEPVAGAFSGVVVGEVVECAQHPDADKLRVTKVNVGGDRLLDIVCG
APNCRQGLKVACATEGAVLPGDFKIKKTKLRGQPSEGMLCSYSELGIKEDHSGIIELPADAPIGKDFREYLDLNDVAIEI
SLTPNRADCLSIAGIAREVGVINRAEVKAPVISEVPATIADKVAVELQAPEACPRYLARVVKNVNVKATSPLWLQEKLRR
CGIRSIDPIVDITNLSLLELGQPMHAFDASKIDGAIQVRMAKEGEELVLLDGTTAKLQPNTLVIADSKGALAMAGIFGGE
ASGVNENTTDVVLESAFFAPLAITGRARQYGLHTDASHRFERGVDPQLARDAMERATALLLEICGGEAGEIVEAVSEQHL
PKRNTVTLRRSKLDAVIGHHIEDETVTDILTRLGLNVIFANDSWTAVAPSWRFDIEIEEDLIEEVARIYGYNSIPNNSPL
AHLTMKGTPEKLLEVNRIRTALVDSDYQEVVTYSFVDPKKQALLHPNQEALILPNPISNEMSAMRLSLLTGLLDTIAYNQ
SRQQTRVRIFEGGLRFIPDAAAESGIRQELVFGAAIVGDKRPVHWESKGEAVDFFDLKGDMERVLSLTSARHDLKFVAKQ
FPALHPGQSAAIMLDGKEIGFIGSVHPSIVQKLGIKGKPVVFEILGDAIANRPVPAAKEISKFPANNRDIAVVVDENVPA
GDVLDACRHAGGVKLVAVNLFDVYRGANLAAGKKSLAISLTVQDTEKTLEEEEISTVIQAVLAELAQRFQAYLRD

Sequences:

>Translated_795_residues
MKFNESWLREWVNPAVSTEQLCDQITMLGLEVDDVEPVAGAFSGVVVGEVVECAQHPDADKLRVTKVNVGGDRLLDIVCG
APNCRQGLKVACATEGAVLPGDFKIKKTKLRGQPSEGMLCSYSELGIKEDHSGIIELPADAPIGKDFREYLDLNDVAIEI
SLTPNRADCLSIAGIAREVGVINRAEVKAPVISEVPATIADKVAVELQAPEACPRYLARVVKNVNVKATSPLWLQEKLRR
CGIRSIDPIVDITNLSLLELGQPMHAFDASKIDGAIQVRMAKEGEELVLLDGTTAKLQPNTLVIADSKGALAMAGIFGGE
ASGVNENTTDVVLESAFFAPLAITGRARQYGLHTDASHRFERGVDPQLARDAMERATALLLEICGGEAGEIVEAVSEQHL
PKRNTVTLRRSKLDAVIGHHIEDETVTDILTRLGLNVIFANDSWTAVAPSWRFDIEIEEDLIEEVARIYGYNSIPNNSPL
AHLTMKGTPEKLLEVNRIRTALVDSDYQEVVTYSFVDPKKQALLHPNQEALILPNPISNEMSAMRLSLLTGLLDTIAYNQ
SRQQTRVRIFEGGLRFIPDAAAESGIRQELVFGAAIVGDKRPVHWESKGEAVDFFDLKGDMERVLSLTSARHDLKFVAKQ
FPALHPGQSAAIMLDGKEIGFIGSVHPSIVQKLGIKGKPVVFEILGDAIANRPVPAAKEISKFPANNRDIAVVVDENVPA
GDVLDACRHAGGVKLVAVNLFDVYRGANLAAGKKSLAISLTVQDTEKTLEEEEISTVIQAVLAELAQRFQAYLRD
>Mature_795_residues
MKFNESWLREWVNPAVSTEQLCDQITMLGLEVDDVEPVAGAFSGVVVGEVVECAQHPDADKLRVTKVNVGGDRLLDIVCG
APNCRQGLKVACATEGAVLPGDFKIKKTKLRGQPSEGMLCSYSELGIKEDHSGIIELPADAPIGKDFREYLDLNDVAIEI
SLTPNRADCLSIAGIAREVGVINRAEVKAPVISEVPATIADKVAVELQAPEACPRYLARVVKNVNVKATSPLWLQEKLRR
CGIRSIDPIVDITNLSLLELGQPMHAFDASKIDGAIQVRMAKEGEELVLLDGTTAKLQPNTLVIADSKGALAMAGIFGGE
ASGVNENTTDVVLESAFFAPLAITGRARQYGLHTDASHRFERGVDPQLARDAMERATALLLEICGGEAGEIVEAVSEQHL
PKRNTVTLRRSKLDAVIGHHIEDETVTDILTRLGLNVIFANDSWTAVAPSWRFDIEIEEDLIEEVARIYGYNSIPNNSPL
AHLTMKGTPEKLLEVNRIRTALVDSDYQEVVTYSFVDPKKQALLHPNQEALILPNPISNEMSAMRLSLLTGLLDTIAYNQ
SRQQTRVRIFEGGLRFIPDAAAESGIRQELVFGAAIVGDKRPVHWESKGEAVDFFDLKGDMERVLSLTSARHDLKFVAKQ
FPALHPGQSAAIMLDGKEIGFIGSVHPSIVQKLGIKGKPVVFEILGDAIANRPVPAAKEISKFPANNRDIAVVVDENVPA
GDVLDACRHAGGVKLVAVNLFDVYRGANLAAGKKSLAISLTVQDTEKTLEEEEISTVIQAVLAELAQRFQAYLRD

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=558, Percent_Identity=24.1935483870968, Blast_Score=88, Evalue=4e-17,
Organism=Escherichia coli, GI1788006, Length=795, Percent_Identity=66.4150943396226, Blast_Score=1056, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17533403, Length=564, Percent_Identity=24.113475177305, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355211, Length=559, Percent_Identity=24.1502683363148, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 86364; Mature: 86364

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNESWLREWVNPAVSTEQLCDQITMLGLEVDDVEPVAGAFSGVVVGEVVECAQHPDAD
CCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KLRVTKVNVGGDRLLDIVCGAPNCRQGLKVACATEGAVLPGDFKIKKTKLRGQPSEGMLC
CEEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEE
SYSELGIKEDHSGIIELPADAPIGKDFREYLDLNDVAIEISLTPNRADCLSIAGIAREVG
EHHHCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHC
VINRAEVKAPVISEVPATIADKVAVELQAPEACPRYLARVVKNVNVKATSPLWLQEKLRR
CCCHHHCCCCHHHHCCHHHHHHEEEEEECCHHHHHHHHHHHHCCCCEECCCHHHHHHHHH
CGIRSIDPIVDITNLSLLELGQPMHAFDASKIDGAIQVRMAKEGEELVLLDGTTAKLQPN
CCCCCCCCCEEECCCHHHHCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEECCC
TLVIADSKGALAMAGIFGGEASGVNENTTDVVLESAFFAPLAITGRARQYGLHTDASHRF
EEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHCCCCCCCHHHH
ERGVDPQLARDAMERATALLLEICGGEAGEIVEAVSEQHLPKRNTVTLRRSKLDAVIGHH
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
IEDETVTDILTRLGLNVIFANDSWTAVAPSWRFDIEIEEDLIEEVARIYGYNSIPNNSPL
CCHHHHHHHHHHCCCEEEEECCCCEEECCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCE
AHLTMKGTPEKLLEVNRIRTALVDSDYQEVVTYSFVDPKKQALLHPNQEALILPNPISNE
EEEEECCCHHHHHHHHHHHHHHHCCCHHHHHEEECCCCHHHHHCCCCCCEEEECCCCCHH
MSAMRLSLLTGLLDTIAYNQSRQQTRVRIFEGGLRFIPDAAAESGIRQELVFGAAIVGDK
HHHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCCHHHHCCHHHHHHHHHHEECCC
RPVHWESKGEAVDFFDLKGDMERVLSLTSARHDLKFVAKQFPALHPGQSAAIMLDGKEIG
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
FIGSVHPSIVQKLGIKGKPVVFEILGDAIANRPVPAAKEISKFPANNRDIAVVVDENVPA
EECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCCC
GDVLDACRHAGGVKLVAVNLFDVYRGANLAAGKKSLAISLTVQDTEKTLEEEEISTVIQA
HHHHHHHHHCCCEEEEEEEEHHHHCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHH
VLAELAQRFQAYLRD
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFNESWLREWVNPAVSTEQLCDQITMLGLEVDDVEPVAGAFSGVVVGEVVECAQHPDAD
CCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KLRVTKVNVGGDRLLDIVCGAPNCRQGLKVACATEGAVLPGDFKIKKTKLRGQPSEGMLC
CEEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCEE
SYSELGIKEDHSGIIELPADAPIGKDFREYLDLNDVAIEISLTPNRADCLSIAGIAREVG
EHHHCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHC
VINRAEVKAPVISEVPATIADKVAVELQAPEACPRYLARVVKNVNVKATSPLWLQEKLRR
CCCHHHCCCCHHHHCCHHHHHHEEEEEECCHHHHHHHHHHHHCCCCEECCCHHHHHHHHH
CGIRSIDPIVDITNLSLLELGQPMHAFDASKIDGAIQVRMAKEGEELVLLDGTTAKLQPN
CCCCCCCCCEEECCCHHHHCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEECCC
TLVIADSKGALAMAGIFGGEASGVNENTTDVVLESAFFAPLAITGRARQYGLHTDASHRF
EEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHCCCCCCCHHHH
ERGVDPQLARDAMERATALLLEICGGEAGEIVEAVSEQHLPKRNTVTLRRSKLDAVIGHH
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
IEDETVTDILTRLGLNVIFANDSWTAVAPSWRFDIEIEEDLIEEVARIYGYNSIPNNSPL
CCHHHHHHHHHHCCCEEEEECCCCEEECCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCE
AHLTMKGTPEKLLEVNRIRTALVDSDYQEVVTYSFVDPKKQALLHPNQEALILPNPISNE
EEEEECCCHHHHHHHHHHHHHHHCCCHHHHHEEECCCCHHHHHCCCCCCEEEECCCCCHH
MSAMRLSLLTGLLDTIAYNQSRQQTRVRIFEGGLRFIPDAAAESGIRQELVFGAAIVGDK
HHHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCCHHHHCCHHHHHHHHHHEECCC
RPVHWESKGEAVDFFDLKGDMERVLSLTSARHDLKFVAKQFPALHPGQSAAIMLDGKEIG
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
FIGSVHPSIVQKLGIKGKPVVFEILGDAIANRPVPAAKEISKFPANNRDIAVVVDENVPA
EECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCCC
GDVLDACRHAGGVKLVAVNLFDVYRGANLAAGKKSLAISLTVQDTEKTLEEEEISTVIQA
HHHHHHHHHCCCEEEEEEEEHHHHCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHH
VLAELAQRFQAYLRD
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA