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The map label for this gene is ihfA

Identifier: 126208092

GI number: 126208092

Start: 697528

End: 697824

Strand: Direct

Name: ihfA

Synonym: APL_0610

Alternate gene names: 126208092

Gene position: 697528-697824 (Clockwise)

Preceding gene: 126208091

Following gene: 126208093

Centisome position: 30.67

GC content: 42.42

Gene sequence:

>297_bases
ATGGCACTCACTAAAATTGAACTCGCAGAAAGCCTCGTTGAAAAATGCGGCTTTGATAAACGTATCGCCAAGCTCTTTGT
AGAGCAATTTTTTGAGGAGATTCGAAGTTCTTTGGAAAAAGGCGAAGAAGTTAAATTATCCGGTTTCGGTAATTTCTCGT
TACGAGAGAAAAATGCACGTCCGGGTAGAAATCCGAAGACTGGTGAAACGGTTGCGGTTACCGCTCGTCGAGTGGTCGTC
TTTAAGCCCGGTCAAAAGCTTAGAGATAGAGTTGAAAATGTAAAAGTGAAGGCATAA

Upstream 100 bases:

>100_bases
TTGAGGAAGAAGAAATTTCGACTGTAATTCAAGCGGTCTTAGCAGAATTGGCACAACGTTTCCAAGCATATCTAAGAGAT
TAGATTTAAGGATTATTTTT

Downstream 100 bases:

>100_bases
ATAAAGACATTCCATAGCCTCTATTGGGGCTTATGGAATGTCTTTTATAGGTAACCTTATATGATTAAATTCAGTCAAAA
ATATTTACCGCTGGCGGCGG

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MALTKIELAESLVEKCGFDKRIAKLFVEQFFEEIRSSLEKGEEVKLSGFGNFSLREKNARPGRNPKTGETVAVTARRVVV
FKPGQKLRDRVENVKVKA

Sequences:

>Translated_98_residues
MALTKIELAESLVEKCGFDKRIAKLFVEQFFEEIRSSLEKGEEVKLSGFGNFSLREKNARPGRNPKTGETVAVTARRVVV
FKPGQKLRDRVENVKVKA
>Mature_97_residues
ALTKIELAESLVEKCGFDKRIAKLFVEQFFEEIRSSLEKGEEVKLSGFGNFSLREKNARPGRNPKTGETVAVTARRVVVF
KPGQKLRDRVENVKVKA

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=97, Percent_Identity=68.0412371134021, Blast_Score=135, Evalue=4e-34,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=40, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=32.5842696629214, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=35.9550561797753, Blast_Score=63, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_ACTP2 (A3MZX6)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053317.1
- ProteinModelPortal:   A3MZX6
- SMR:   A3MZX6
- STRING:   A3MZX6
- GeneID:   4848771
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0610
- eggNOG:   COG0776
- HOGENOM:   HBG705085
- OMA:   RPKVTKS
- PhylomeDB:   A3MZX6
- ProtClustDB:   PRK00285
- BioCyc:   APLE416269:APL_0610-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11082; Mature: 10951

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKIELAESLVEKCGFDKRIAKLFVEQFFEEIRSSLEKGEEVKLSGFGNFSLREKNAR
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCC
PGRNPKTGETVAVTARRVVVFKPGQKLRDRVENVKVKA
CCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALTKIELAESLVEKCGFDKRIAKLFVEQFFEEIRSSLEKGEEVKLSGFGNFSLREKNAR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCC
PGRNPKTGETVAVTARRVVVFKPGQKLRDRVENVKVKA
CCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA