BacMap

Definition	Actinobacillus pleuropneumoniae serovar 5b str. L20 chromosome, complete genome.
Accession	NC_009053
Length	2,274,482

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The map label for this gene is ftsH [H]

Identifier: 126208077

GI number: 126208077

Start: 679502

End: 681424

Strand: Direct

Name: ftsH [H]

Synonym: APL_0595

Alternate gene names: 126208077

Gene position: 679502-681424 (Clockwise)

Preceding gene: 126208076

Following gene: 126208078

Centisome position: 29.88

GC content: 45.35

Gene sequence:

>1923_bases
ATGGTTAAAAATATAATCCTTTGGGTAGTGGTCGCTATCGTGTTGATGACTGCTTTTGAAGGGTTTAATTCAAACTTTGG
TAACAACAATACGGTTGCTTATTCAACTTTCTTGAACGATATTAAATCGAATAACCTCAAAGAAGTGGATTTCAAACGTA
ACGATGAAACCATTTCCGTGACTAAAAACGACGGTACGCAATACCAAACCGTAATGCCGATGTATGACGAATACTTATTA
GCGGATTTGGCGAAAACAAACGCTACCGTGACCGGTCAGCCGGAAGAACGTCGCGGTTTGTTATCTCAAATCTTAATCTC
GTGGTTCCCGATGATAATGCTGATCGGCTTCTGGCTGTTTTATATGCGCCAGATGCAAGGCGGAGGCGGTCGAGGCGCAA
TGAGCTTTGGTAAAAGCAAAGCAAAAATGCTGACGGCGGAGCAGGTTAAAACACGTTTTACCGATGTTGCGGGCTGCGAC
GAAGCAAAAGAAGAAGTCGGTGAAGTAGTGGACTTTTTAAAAGATCCGAGCAAATTCCAAAAACTGGGCGGACGTATTCC
GAAAGGTATCTTAATGGTTGGTCCTCCGGGTACGGGTAAAACGTTATTAGCGAAAGCGATTGCCGGTGAAGCGGGTGTGC
CGTTCTTTACTATGGCGGGTTCCGACTTCGTAGAAATGTTTGTCGGTGTCGGTGCTTCTCGTGTACGTGATCTTTTTGAA
CAAGCGAAGAAAAACGCACCTTGCATTATCTTTATCGATGAAATTGATGCGGTAGGTCGCAAACGTGGCGGAGCCGGTTT
CAGCGGCGGTCACGATGAGCGCGAACAAACGCTTAACCAAATGTTAGTTGAGATGGACGGTTTTGAAGGTTCGGAAGGGG
TGATTATTATTGCTGCGACTAACCGTGCCGATGTGCTTGATGACGCTTTAACTCGTCCGGGACGTTTCGACCGTCAAGTA
ACGGTCGATTTACCGAATGTAAAAGGTCGCGAGCAAATCTTAAAAGTACATATGAAAAAAGTACCGCTTGCACCGGATGT
TGATCCGATGGTGGTCGCACGCGGTACGCCGGGTTATTCGGGTGCGCAATTGGCAAACTTGGTTAATGAAGCGGCATTAT
TCGCAGCGCGTAAAAATCAGCGCGTAGTCACTATGCTCGATTTTGAGCAAGCACGCGATAAAATCAATATGGGACCGGAA
CGTCGTTCAAATACGATGACGGAAAAAGAATTGATGAATACCGCTTATCATGAAGCCGGTCACGTAATTGTCGGTTATTT
AATGCCGGAACACGATCCGCTCAATAAAGTGACGATTGTGCCGCGCGGTCAAGCGCTTGGTTTTGCGCAATTTTTACCGG
AAGGCGACCGTGTGAGCGAAACCTTTACTAAGTTAGAAAGCCAGCTTTCAACCCTATTTGCAGGTCGAATTGCCGAAGGA
CTTATTTTTGGTGAAGATAAAATTACCACCGGTGCGTCTTCGGATATTCACCGTGCGACCCAAATTGCTCGTGCAATGGT
AACTCAATGGGGTTTCTCTAAAGAGTTAGGGCCGTTGTTCTATCAAAACGAAGATGGTATGGGAGCAATCAAAGGTGTAT
CGGAAGAATCGCAAAAACTGATTGACCAAGAAATGCGTAAGCTTATCGATCGTAACTATGAGCGAGCGAAGAAAACCTTA
GAAGACAATATAGATATTTTACATGCGATGAAAGATGCGTTGTTAAAATATGAAACATTAGATCGTAAACAAATTGACGA
CTTAATGAATCGTCGTCCGGTTGGTGAACCGGCGGGTTGGAACGATAAAGGTGATGACAGTTCGTCAAGCGATTCCGCAA
CGACATCAAAAAGTGATGAAGAACAGCCGTCTAAAGATATTCCGCATACCGATGCGGTAGCCGATAAGCAGGCGGATGCT
TAA

Upstream 100 bases:

>100_bases
AAGCGGTCAAGTTTTGCAGAAATTTTGTAAAATCCGACCGCTTGTTAAAATGAAGATAACGAATTTTTTATTCTAAAAGA
GGAAATTAACCTTGAACGAT

Downstream 100 bases:

>100_bases
TTATTCGTCATAAATGAATAAAGCCGAGAAGCGAAAGTTTCTCGGCTTTTTTGTGTAAGAAATTGTCGATTTTACAAGCG
GTTGAATTTCATTGGAAACT

Product: cell division protease FtsH-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MVKNIILWVVVAIVLMTAFEGFNSNFGNNNTVAYSTFLNDIKSNNLKEVDFKRNDETISVTKNDGTQYQTVMPMYDEYLL
ADLAKTNATVTGQPEERRGLLSQILISWFPMIMLIGFWLFYMRQMQGGGGRGAMSFGKSKAKMLTAEQVKTRFTDVAGCD
EAKEEVGEVVDFLKDPSKFQKLGGRIPKGILMVGPPGTGKTLLAKAIAGEAGVPFFTMAGSDFVEMFVGVGASRVRDLFE
QAKKNAPCIIFIDEIDAVGRKRGGAGFSGGHDEREQTLNQMLVEMDGFEGSEGVIIIAATNRADVLDDALTRPGRFDRQV
TVDLPNVKGREQILKVHMKKVPLAPDVDPMVVARGTPGYSGAQLANLVNEAALFAARKNQRVVTMLDFEQARDKINMGPE
RRSNTMTEKELMNTAYHEAGHVIVGYLMPEHDPLNKVTIVPRGQALGFAQFLPEGDRVSETFTKLESQLSTLFAGRIAEG
LIFGEDKITTGASSDIHRATQIARAMVTQWGFSKELGPLFYQNEDGMGAIKGVSEESQKLIDQEMRKLIDRNYERAKKTL
EDNIDILHAMKDALLKYETLDRKQIDDLMNRRPVGEPAGWNDKGDDSSSSDSATTSKSDEEQPSKDIPHTDAVADKQADA

Sequences:

>Translated_640_residues
MVKNIILWVVVAIVLMTAFEGFNSNFGNNNTVAYSTFLNDIKSNNLKEVDFKRNDETISVTKNDGTQYQTVMPMYDEYLL
ADLAKTNATVTGQPEERRGLLSQILISWFPMIMLIGFWLFYMRQMQGGGGRGAMSFGKSKAKMLTAEQVKTRFTDVAGCD
EAKEEVGEVVDFLKDPSKFQKLGGRIPKGILMVGPPGTGKTLLAKAIAGEAGVPFFTMAGSDFVEMFVGVGASRVRDLFE
QAKKNAPCIIFIDEIDAVGRKRGGAGFSGGHDEREQTLNQMLVEMDGFEGSEGVIIIAATNRADVLDDALTRPGRFDRQV
TVDLPNVKGREQILKVHMKKVPLAPDVDPMVVARGTPGYSGAQLANLVNEAALFAARKNQRVVTMLDFEQARDKINMGPE
RRSNTMTEKELMNTAYHEAGHVIVGYLMPEHDPLNKVTIVPRGQALGFAQFLPEGDRVSETFTKLESQLSTLFAGRIAEG
LIFGEDKITTGASSDIHRATQIARAMVTQWGFSKELGPLFYQNEDGMGAIKGVSEESQKLIDQEMRKLIDRNYERAKKTL
EDNIDILHAMKDALLKYETLDRKQIDDLMNRRPVGEPAGWNDKGDDSSSSDSATTSKSDEEQPSKDIPHTDAVADKQADA
>Mature_640_residues
MVKNIILWVVVAIVLMTAFEGFNSNFGNNNTVAYSTFLNDIKSNNLKEVDFKRNDETISVTKNDGTQYQTVMPMYDEYLL
ADLAKTNATVTGQPEERRGLLSQILISWFPMIMLIGFWLFYMRQMQGGGGRGAMSFGKSKAKMLTAEQVKTRFTDVAGCD
EAKEEVGEVVDFLKDPSKFQKLGGRIPKGILMVGPPGTGKTLLAKAIAGEAGVPFFTMAGSDFVEMFVGVGASRVRDLFE
QAKKNAPCIIFIDEIDAVGRKRGGAGFSGGHDEREQTLNQMLVEMDGFEGSEGVIIIAATNRADVLDDALTRPGRFDRQV
TVDLPNVKGREQILKVHMKKVPLAPDVDPMVVARGTPGYSGAQLANLVNEAALFAARKNQRVVTMLDFEQARDKINMGPE
RRSNTMTEKELMNTAYHEAGHVIVGYLMPEHDPLNKVTIVPRGQALGFAQFLPEGDRVSETFTKLESQLSTLFAGRIAEG
LIFGEDKITTGASSDIHRATQIARAMVTQWGFSKELGPLFYQNEDGMGAIKGVSEESQKLIDQEMRKLIDRNYERAKKTL
EDNIDILHAMKDALLKYETLDRKQIDDLMNRRPVGEPAGWNDKGDDSSSSDSATTSKSDEEQPSKDIPHTDAVADKQADA

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI7657689, Length=437, Percent_Identity=54.233409610984, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI21327685, Length=433, Percent_Identity=54.7344110854504, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI300192933, Length=524, Percent_Identity=44.6564885496183, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI4507173, Length=505, Percent_Identity=43.5643564356436, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI24497435, Length=254, Percent_Identity=41.3385826771654, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=40.1574803149606, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI21361144, Length=267, Percent_Identity=40.0749063670412, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI195539395, Length=244, Percent_Identity=40.5737704918033, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI6005942, Length=236, Percent_Identity=44.0677966101695, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI24430151, Length=246, Percent_Identity=39.4308943089431, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI89064750, Length=255, Percent_Identity=40.7843137254902, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI5729991, Length=255, Percent_Identity=40.7843137254902, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI24430155, Length=255, Percent_Identity=40.7843137254902, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI45643123, Length=259, Percent_Identity=40.1544401544402, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI45643125, Length=259, Percent_Identity=40.1544401544402, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI40806173, Length=177, Percent_Identity=54.2372881355932, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI157671927, Length=224, Percent_Identity=40.1785714285714, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI5901990, Length=277, Percent_Identity=36.101083032491, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI14149767, Length=275, Percent_Identity=37.4545454545455, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI62177112, Length=275, Percent_Identity=37.4545454545455, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI4505725, Length=214, Percent_Identity=39.2523364485981, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI229577436, Length=247, Percent_Identity=37.6518218623482, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI24497618, Length=236, Percent_Identity=38.135593220339, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI153792536, Length=235, Percent_Identity=38.2978723404255, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI194018488, Length=277, Percent_Identity=35.0180505415162, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI7019569, Length=272, Percent_Identity=34.5588235294118, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=36.7088607594937, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI17865802, Length=264, Percent_Identity=35.2272727272727, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI31742536, Length=255, Percent_Identity=33.7254901960784, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI112789543, Length=255, Percent_Identity=33.7254901960784, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI11875211, Length=229, Percent_Identity=39.7379912663755, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI40806170, Length=229, Percent_Identity=39.7379912663755, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI156564401, Length=236, Percent_Identity=36.4406779661017, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI310125280, Length=236, Percent_Identity=36.0169491525424, Blast_Score=126, Evalue=8e-29,
Organism=Homo sapiens, GI310125282, Length=236, Percent_Identity=36.0169491525424, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI31377644, Length=235, Percent_Identity=36.1702127659575, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI64084766, Length=316, Percent_Identity=28.1645569620253, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI116292174, Length=249, Percent_Identity=28.1124497991968, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI75677353, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI283436222, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI283436224, Length=196, Percent_Identity=31.1224489795918, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI283436220, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1789568, Length=621, Percent_Identity=65.2173913043478, Blast_Score=857, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=466, Percent_Identity=48.4978540772532, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17554264, Length=451, Percent_Identity=48.780487804878, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI115534323, Length=453, Percent_Identity=46.7991169977925, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17554786, Length=241, Percent_Identity=43.9834024896266, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI25144278, Length=241, Percent_Identity=43.9834024896266, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25144281, Length=241, Percent_Identity=43.9834024896266, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17563248, Length=264, Percent_Identity=40.9090909090909, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17532375, Length=251, Percent_Identity=39.4422310756972, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=255, Percent_Identity=40, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71987364, Length=244, Percent_Identity=40.9836065573771, Blast_Score=192, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=244, Percent_Identity=40.9836065573771, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=244, Percent_Identity=39.344262295082, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17531535, Length=247, Percent_Identity=39.2712550607287, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17505546, Length=243, Percent_Identity=41.5637860082305, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17508053, Length=245, Percent_Identity=42.4489795918367, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17554784, Length=255, Percent_Identity=40.3921568627451, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17537217, Length=194, Percent_Identity=44.3298969072165, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI25153574, Length=237, Percent_Identity=39.662447257384, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI133931034, Length=245, Percent_Identity=38.7755102040816, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=245, Percent_Identity=38.7755102040816, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193206116, Length=245, Percent_Identity=38.7755102040816, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.6666666666667, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.6666666666667, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=230, Percent_Identity=40, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17562804, Length=231, Percent_Identity=37.2294372294372, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=249, Percent_Identity=36.5461847389558, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86561515, Length=244, Percent_Identity=34.8360655737705, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI133901658, Length=214, Percent_Identity=39.2523364485981, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=214, Percent_Identity=39.2523364485981, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=250, Percent_Identity=36.4, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508421, Length=244, Percent_Identity=36.4754098360656, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=236, Percent_Identity=34.3220338983051, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17541224, Length=236, Percent_Identity=34.3220338983051, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17560432, Length=256, Percent_Identity=32.8125, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990294, Length=199, Percent_Identity=30.6532663316583, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323736, Length=507, Percent_Identity=46.5483234714004, Blast_Score=461, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325281, Length=449, Percent_Identity=50.5567928730512, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6320854, Length=513, Percent_Identity=45.224171539961, Blast_Score=438, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6322704, Length=264, Percent_Identity=40.9090909090909, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324691, Length=252, Percent_Identity=42.8571428571429, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320077, Length=241, Percent_Identity=40.6639004149378, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6324833, Length=254, Percent_Identity=41.3385826771654, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=41.49377593361, Blast_Score=193, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6320197, Length=244, Percent_Identity=37.7049180327869, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6320602, Length=251, Percent_Identity=40.6374501992032, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323429, Length=256, Percent_Identity=39.84375, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324000, Length=233, Percent_Identity=40.7725321888412, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322651, Length=249, Percent_Identity=34.5381526104418, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6322994, Length=214, Percent_Identity=36.4485981308411, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=38.9830508474576, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6325431, Length=269, Percent_Identity=35.6877323420074, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319554, Length=220, Percent_Identity=36.8181818181818, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321465, Length=241, Percent_Identity=35.2697095435685, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=260, Percent_Identity=33.4615384615385, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=267, Percent_Identity=32.9588014981273, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=218, Percent_Identity=28.4403669724771, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24658770, Length=444, Percent_Identity=49.5495495495495, Blast_Score=437, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24665814, Length=524, Percent_Identity=43.5114503816794, Blast_Score=431, Evalue=1e-120,
Organism=Drosophila melanogaster, GI28574878, Length=524, Percent_Identity=43.5114503816794, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24639391, Length=456, Percent_Identity=46.4912280701754, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=60.7361963190184, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920408, Length=244, Percent_Identity=42.6229508196721, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24651451, Length=256, Percent_Identity=41.40625, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI161076486, Length=251, Percent_Identity=41.8326693227092, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17137560, Length=251, Percent_Identity=41.8326693227092, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI161076488, Length=251, Percent_Identity=41.8326693227092, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17137738, Length=244, Percent_Identity=42.2131147540984, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17738151, Length=263, Percent_Identity=39.9239543726236, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24649446, Length=244, Percent_Identity=39.344262295082, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=40, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=39.5918367346939, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24660075, Length=233, Percent_Identity=43.3476394849785, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI281365776, Length=233, Percent_Identity=43.3476394849785, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI45552965, Length=233, Percent_Identity=43.3476394849785, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI18860063, Length=245, Percent_Identity=40.4081632653061, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24663015, Length=244, Percent_Identity=40.5737704918033, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI281361487, Length=254, Percent_Identity=38.9763779527559, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24652279, Length=192, Percent_Identity=44.7916666666667, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656820, Length=227, Percent_Identity=37.4449339207048, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24656825, Length=227, Percent_Identity=37.4449339207048, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24644145, Length=249, Percent_Identity=38.9558232931727, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI281360136, Length=231, Percent_Identity=37.6623376623377, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24644411, Length=231, Percent_Identity=37.6623376623377, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281360144, Length=231, Percent_Identity=37.6623376623377, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360140, Length=231, Percent_Identity=37.6623376623377, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360146, Length=232, Percent_Identity=38.3620689655172, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360138, Length=232, Percent_Identity=38.3620689655172, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360142, Length=231, Percent_Identity=37.6623376623377, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21357333, Length=231, Percent_Identity=37.6623376623377, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281363136, Length=248, Percent_Identity=37.5, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI78707192, Length=248, Percent_Identity=37.5, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859657, Length=243, Percent_Identity=37.8600823045267, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20129529, Length=277, Percent_Identity=32.8519855595668, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573010, Length=214, Percent_Identity=40.1869158878505, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21355121, Length=220, Percent_Identity=34.0909090909091, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864540, Length=211, Percent_Identity=40.2843601895735, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24581396, Length=259, Percent_Identity=36.2934362934363, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28571849, Length=251, Percent_Identity=37.4501992031873, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28571847, Length=251, Percent_Identity=37.4501992031873, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20129423, Length=243, Percent_Identity=32.5102880658436, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24639486, Length=194, Percent_Identity=36.0824742268041, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 70598; Mature: 70598

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNIILWVVVAIVLMTAFEGFNSNFGNNNTVAYSTFLNDIKSNNLKEVDFKRNDETISV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEECCCCCCCCEEEE
TKNDGTQYQTVMPMYDEYLLADLAKTNATVTGQPEERRGLLSQILISWFPMIMLIGFWLF
ECCCCCCEEEEHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YMRQMQGGGGRGAMSFGKSKAKMLTAEQVKTRFTDVAGCDEAKEEVGEVVDFLKDPSKFQ
HHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
KLGGRIPKGILMVGPPGTGKTLLAKAIAGEAGVPFFTMAGSDFVEMFVGVGASRVRDLFE
HHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHH
QAKKNAPCIIFIDEIDAVGRKRGGAGFSGGHDEREQTLNQMLVEMDGFEGSEGVIIIAAT
HHHCCCCEEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRADVLDDALTRPGRFDRQVTVDLPNVKGREQILKVHMKKVPLAPDVDPMVVARGTPGYS
CCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
GAQLANLVNEAALFAARKNQRVVTMLDFEQARDKINMGPERRSNTMTEKELMNTAYHEAG
HHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCC
HVIVGYLMPEHDPLNKVTIVPRGQALGFAQFLPEGDRVSETFTKLESQLSTLFAGRIAEG
CEEEEEECCCCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LIFGEDKITTGASSDIHRATQIARAMVTQWGFSKELGPLFYQNEDGMGAIKGVSEESQKL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHCCCCHHHHHH
IDQEMRKLIDRNYERAKKTLEDNIDILHAMKDALLKYETLDRKQIDDLMNRRPVGEPAGW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
NDKGDDSSSSDSATTSKSDEEQPSKDIPHTDAVADKQADA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MVKNIILWVVVAIVLMTAFEGFNSNFGNNNTVAYSTFLNDIKSNNLKEVDFKRNDETISV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEECCCCCCCCEEEE
TKNDGTQYQTVMPMYDEYLLADLAKTNATVTGQPEERRGLLSQILISWFPMIMLIGFWLF
ECCCCCCEEEEHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YMRQMQGGGGRGAMSFGKSKAKMLTAEQVKTRFTDVAGCDEAKEEVGEVVDFLKDPSKFQ
HHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
KLGGRIPKGILMVGPPGTGKTLLAKAIAGEAGVPFFTMAGSDFVEMFVGVGASRVRDLFE
HHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHH
QAKKNAPCIIFIDEIDAVGRKRGGAGFSGGHDEREQTLNQMLVEMDGFEGSEGVIIIAAT
HHHCCCCEEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRADVLDDALTRPGRFDRQVTVDLPNVKGREQILKVHMKKVPLAPDVDPMVVARGTPGYS
CCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
GAQLANLVNEAALFAARKNQRVVTMLDFEQARDKINMGPERRSNTMTEKELMNTAYHEAG
HHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCC
HVIVGYLMPEHDPLNKVTIVPRGQALGFAQFLPEGDRVSETFTKLESQLSTLFAGRIAEG
CEEEEEECCCCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LIFGEDKITTGASSDIHRATQIARAMVTQWGFSKELGPLFYQNEDGMGAIKGVSEESQKL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHCCCCHHHHHH
IDQEMRKLIDRNYERAKKTLEDNIDILHAMKDALLKYETLDRKQIDDLMNRRPVGEPAGW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
NDKGDDSSSSDSATTSKSDEEQPSKDIPHTDAVADKQADA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]