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The map label for this gene is nudC [H]

Identifier: 126207575

GI number: 126207575

Start: 94861

End: 95631

Strand: Reverse

Name: nudC [H]

Synonym: APL_0087

Alternate gene names: 126207575

Gene position: 95631-94861 (Counterclockwise)

Preceding gene: 126207576

Following gene: 126207571

Centisome position: 4.2

GC content: 43.71

Gene sequence:

>771_bases
ATGAAAAGTTATTGGGTATTAGTACATCATTTTGATCTTGCTTTAAAAGATGATGAAATTCCTTTCGGTACAGCCGAACA
ATTAGGTCTAGTCGGCTTTGCTAAATTACAGGTTGGAGAATACCAAAACTCACCGGTTTTTCTAGTACAATTGAATGAGC
AAGCGGTCGAAAATCTACAAAATTTTACCATGGTGAACCTACGCTCACAGATTGCTCTCCCAGAGGAATTAGCTCACCTA
TTACACCGAGCCGTTTCACTTAATCATTTCCTCAATACGCATAAATTCTGTGGTAAATGTGGTGCTCACACCGAACTTGC
TGATAACGAAATAGCGATTCATTGCCCAAATTGCCAACATCGTAGCTACCCGACTATCAGCCCGTCTATTATCGTGGCGG
TACGCCGTGGACGACAAATTTTACTCGCCAACCATCTGCGTCATAAAGGTACGATTTACACCACATTGGCCGGTTTTGTC
GAAGCCGGTGAAGCGATCGAAACCACCGTTCAACGTGAAGTATGGGAAGAAAGCGGCTTAAAAATCAAAAATATCCGCTA
TTTCGGCAGCCAACCGTGGGCATTCCCTAACTCACTGATGTTAAGTTTTCTCGCCGATTATGATAGCGGAGAAATCACGC
TACAAGAGGAAGAAATCTTCGATGCCAAATGGTTCGATTGCGATCAACCACTTCCGGAACTGCCACCGGAAGGCACGATT
GCATTGGAGCTAATCAAAGAAACGCTGAAGATTTGTCGAGAGGAAGGATAA

Upstream 100 bases:

>100_bases
GCGAGTTAAATAGCGGTGAATATCGAGTTTTAGATGAAAAAGAAAAACGCCAATTATTTCAACAAATTGACTTAAAAATT
TAATGATTTCGGGAGCAAAT

Downstream 100 bases:

>100_bases
CAATAATTTTATAAAGGGCTAATTAAGCCTAAACAAAAACAGGGAGAATTAAATTCTCCCTGTTGTTTTAAGATTAGCTA
AATAATTTACCTAATACACC

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKSYWVLVHHFDLALKDDEIPFGTAEQLGLVGFAKLQVGEYQNSPVFLVQLNEQAVENLQNFTMVNLRSQIALPEELAHL
LHRAVSLNHFLNTHKFCGKCGAHTELADNEIAIHCPNCQHRSYPTISPSIIVAVRRGRQILLANHLRHKGTIYTTLAGFV
EAGEAIETTVQREVWEESGLKIKNIRYFGSQPWAFPNSLMLSFLADYDSGEITLQEEEIFDAKWFDCDQPLPELPPEGTI
ALELIKETLKICREEG

Sequences:

>Translated_256_residues
MKSYWVLVHHFDLALKDDEIPFGTAEQLGLVGFAKLQVGEYQNSPVFLVQLNEQAVENLQNFTMVNLRSQIALPEELAHL
LHRAVSLNHFLNTHKFCGKCGAHTELADNEIAIHCPNCQHRSYPTISPSIIVAVRRGRQILLANHLRHKGTIYTTLAGFV
EAGEAIETTVQREVWEESGLKIKNIRYFGSQPWAFPNSLMLSFLADYDSGEITLQEEEIFDAKWFDCDQPLPELPPEGTI
ALELIKETLKICREEG
>Mature_256_residues
MKSYWVLVHHFDLALKDDEIPFGTAEQLGLVGFAKLQVGEYQNSPVFLVQLNEQAVENLQNFTMVNLRSQIALPEELAHL
LHRAVSLNHFLNTHKFCGKCGAHTELADNEIAIHCPNCQHRSYPTISPSIIVAVRRGRQILLANHLRHKGTIYTTLAGFV
EAGEAIETTVQREVWEESGLKIKNIRYFGSQPWAFPNSLMLSFLADYDSGEITLQEEEIFDAKWFDCDQPLPELPPEGTI
ALELIKETLKICREEG

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=201, Percent_Identity=35.8208955223881, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI50593112, Length=191, Percent_Identity=33.5078534031414, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI48994995, Length=253, Percent_Identity=46.2450592885375, Blast_Score=234, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI212645999, Length=237, Percent_Identity=27.0042194092827, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71986510, Length=237, Percent_Identity=27.0042194092827, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321371, Length=209, Percent_Identity=29.1866028708134, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 28997; Mature: 28997

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYWVLVHHFDLALKDDEIPFGTAEQLGLVGFAKLQVGEYQNSPVFLVQLNEQAVENLQ
CCCEEEEEEEEEEEEECCCCCCCCHHHHCCEEEEEEEECCCCCCCEEEEEECHHHHHHHH
NFTMVNLRSQIALPEELAHLLHRAVSLNHFLNTHKFCGKCGAHTELADNEIAIHCPNCQH
HCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCCC
RSYPTISPSIIVAVRRGRQILLANHLRHKGTIYTTLAGFVEAGEAIETTVQREVWEESGL
CCCCCCCCCEEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KIKNIRYFGSQPWAFPNSLMLSFLADYDSGEITLQEEEIFDAKWFDCDQPLPELPPEGTI
EEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHH
ALELIKETLKICREEG
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSYWVLVHHFDLALKDDEIPFGTAEQLGLVGFAKLQVGEYQNSPVFLVQLNEQAVENLQ
CCCEEEEEEEEEEEEECCCCCCCCHHHHCCEEEEEEEECCCCCCCEEEEEECHHHHHHHH
NFTMVNLRSQIALPEELAHLLHRAVSLNHFLNTHKFCGKCGAHTELADNEIAIHCPNCQH
HCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCCC
RSYPTISPSIIVAVRRGRQILLANHLRHKGTIYTTLAGFVEAGEAIETTVQREVWEESGL
CCCCCCCCCEEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KIKNIRYFGSQPWAFPNSLMLSFLADYDSGEITLQEEEIFDAKWFDCDQPLPELPPEGTI
EEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHH
ALELIKETLKICREEG
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA