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The map label for this gene is gsiC [H]

Identifier: 126207516

GI number: 126207516

Start: 32792

End: 33739

Strand: Reverse

Name: gsiC [H]

Synonym: APL_0028

Alternate gene names: 126207516

Gene position: 33739-32792 (Counterclockwise)

Preceding gene: 126207517

Following gene: 126207515

Centisome position: 1.48

GC content: 45.89

Gene sequence:

>948_bases
ATGCTTAAGATTATTTTCAGACGCCTACTGCAAATTATTTTAGTGATTTGGTCGGTCGGCACGCTTACTTTTATTTTGAC
ACGACAACTCTCCGGCGATATGGCTTATCGTATTGCGGCAAGTCGTTACGGTTATGATCAAGTCGATAGTGCCGCCGCCG
ATTTAGTTCGTACCGAATTAGGTCTAGACCAACCTTGGTGGCAAAGCTACGGCAACTGGCTACTTGATCTTTTACAACTT
AATTTAGGTAAATCTTTAGTTACCGGCGATTCGGTTTGGAGTGAAATTGCCCATCAATTCGGGCATACACTTAGTCTTGC
TCTGGTTGCGCTCGTTATGGCAATTATGATTGGTCCGATTCTTGGTGTACTTGCCGCTCGCAAAGAAAACGGCTTTTTTG
ACCGCTTTACCTTGGTATTCAGCACGCTGTTTCGCTCCGTACCGGCATTTATTATCGCTATCGGACTGATTACGCTCTTT
TCGGCGACATTACGTTGGCTGCCTGCCGGCGGTTACGGTAAATGGCAACATTTTGTTTTACCGGCTTTTACTTTGGCATT
AGGTTTAAGTGCGGTTTCTGTTCGTGTGACACGTGCCGCAATGTTACAGGTAAAACAATCCGAATATTACCAATTTGCGC
GTTTAAAGGGGCTTTCAAAATGGCAAACTTTTACCCGCCACGGTATCCGCAATATTGCGATTCCGGTCATTGCTTACCAT
GCGGTACAGTTGGTTTATCTGATTGAAGGTGTGGTCGTGGTAGAAAGTCTCTTCGCTTGGCCGGGCAGCGGACACGCTTT
AGTACACGCCATTATTGCCAGAGACGTACCGATGATCCAAGGGACTTCTCTCGTAATGGGCGGTCTATTTGTCCTGTTAA
ATATGTGTGCGGATATGCTAAGTGCGTGGATTGACCCGCGAATTACCCATAAACGTCATGGAGAATAA

Upstream 100 bases:

>100_bases
AAAATAACATGATAAAAATTTAGCATTAAAAACACGGAAAACAGCATACAAATTTAAGCCGCTTTCCGTGTTTTTTATAT
GAATTCTCACGGTTAAAAAT

Downstream 100 bases:

>100_bases
CAATGAATAAAATGACATTTAGCCAAAAAATAGGGGCGATAATTCTTACTATATTACTCGCTTTTGCCTTTTTACAGCCT
TATTTTTACCCGATGGATAT

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLKIIFRRLLQIILVIWSVGTLTFILTRQLSGDMAYRIAASRYGYDQVDSAAADLVRTELGLDQPWWQSYGNWLLDLLQL
NLGKSLVTGDSVWSEIAHQFGHTLSLALVALVMAIMIGPILGVLAARKENGFFDRFTLVFSTLFRSVPAFIIAIGLITLF
SATLRWLPAGGYGKWQHFVLPAFTLALGLSAVSVRVTRAAMLQVKQSEYYQFARLKGLSKWQTFTRHGIRNIAIPVIAYH
AVQLVYLIEGVVVVESLFAWPGSGHALVHAIIARDVPMIQGTSLVMGGLFVLLNMCADMLSAWIDPRITHKRHGE

Sequences:

>Translated_315_residues
MLKIIFRRLLQIILVIWSVGTLTFILTRQLSGDMAYRIAASRYGYDQVDSAAADLVRTELGLDQPWWQSYGNWLLDLLQL
NLGKSLVTGDSVWSEIAHQFGHTLSLALVALVMAIMIGPILGVLAARKENGFFDRFTLVFSTLFRSVPAFIIAIGLITLF
SATLRWLPAGGYGKWQHFVLPAFTLALGLSAVSVRVTRAAMLQVKQSEYYQFARLKGLSKWQTFTRHGIRNIAIPVIAYH
AVQLVYLIEGVVVVESLFAWPGSGHALVHAIIARDVPMIQGTSLVMGGLFVLLNMCADMLSAWIDPRITHKRHGE
>Mature_315_residues
MLKIIFRRLLQIILVIWSVGTLTFILTRQLSGDMAYRIAASRYGYDQVDSAAADLVRTELGLDQPWWQSYGNWLLDLLQL
NLGKSLVTGDSVWSEIAHQFGHTLSLALVALVMAIMIGPILGVLAARKENGFFDRFTLVFSTLFRSVPAFIIAIGLITLF
SATLRWLPAGGYGKWQHFVLPAFTLALGLSAVSVRVTRAAMLQVKQSEYYQFARLKGLSKWQTFTRHGIRNIAIPVIAYH
AVQLVYLIEGVVVVESLFAWPGSGHALVHAIIARDVPMIQGTSLVMGGLFVLLNMCADMLSAWIDPRITHKRHGE

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=311, Percent_Identity=36.9774919614148, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=37.3417721518987, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789965, Length=343, Percent_Identity=30.6122448979592, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787497, Length=313, Percent_Identity=29.073482428115, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=33.134328358209, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=25.2707581227437, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788504, Length=356, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35054; Mature: 35054

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]