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The map label for this gene is srlR [H]

Identifier: 126176543

GI number: 126176543

Start: 5105488

End: 5106261

Strand: Reverse

Name: srlR [H]

Synonym: Sbal_4362

Alternate gene names: 126176543

Gene position: 5106261-5105488 (Counterclockwise)

Preceding gene: 126176544

Following gene: 126176542

Centisome position: 99.59

GC content: 49.61

Gene sequence:

>774_bases
ATGAACAAACGAAACACACAGCAGCGTCGCCACAGCATAATCACCATATTGAACGAACTGGGTGAAGTGAGTGTTGATGA
ACTGTCGTTACGTTTTGAAACCTCAGAAGTGACGATTCGCAAAGATCTGGCTGCGCTTGAGAAAACAGGCCTGCTGCTGC
GCCGTTACGGTGGCGCCGTGGCGATTCCTGACGAAGTGACCCAACAGTTTTCTGCCAAAATCGCGCCTAATAAGCTGTCT
ATTGCAAAAACCGCCGCGCAGCTGATCAAAGATCACAATCGCATCATTATCGATAGCGGCACTACGACTTCTGGCTTGAT
TGAACAGCTGAACGATAAGCGTGGGCTGGTGGTCATGACGAATGCATTGCACCTTGCCAATGCCATCCATGAACTTGAAA
ACGAGCCAACCTTATTGATGACCGGTGGTACTTGGGACCCGCATTCTGAATCATTTCAAGGCCAAGTCGCCGAGCAAGTG
TTGCGCTCATATAACTTCGATCAACTGTTTATCGGTGCCGATGGTATCGATCTTGAACGCGGCACCACTACCTTTAACGA
GTTAACTGGCCTAAGCAAAGTCATGGCCGAAGTGTCCCGCGAAGTGATCGTTATGGTGGATTCAGACAAAATCGGCAAGC
GGATCCCTAACTTAGAGTTGCCGTGGGCTAAAGTCAGTGTGTTGGTCACCGACGATCGTATCGACAAGTGTGCGCTAAAA
CAAATTTCAGATCAGGGCGTGCGAGTTATGCTAGCGCCCTACGCTCATGAGTGA

Upstream 100 bases:

>100_bases
AAATACGCCGTAACATGCGAAACAGTGTTTCGAATACTAGCAAAAAAGTTTCGTTTCACTATAATGCATCTTTCGAATCG
AAACTTATCTGAAAGGTTTT

Downstream 100 bases:

>100_bases
GTGCAAAATAACTTAACAACTTCATTTTTAATTTATAGGTAAAGACTATGTGTGGAATCGTAGGCGCCGTGGCGCAAAGG
GATGTGGCTGAAATTCTGGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNKRNTQQRRHSIITILNELGEVSVDELSLRFETSEVTIRKDLAALEKTGLLLRRYGGAVAIPDEVTQQFSAKIAPNKLS
IAKTAAQLIKDHNRIIIDSGTTTSGLIEQLNDKRGLVVMTNALHLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVIVMVDSDKIGKRIPNLELPWAKVSVLVTDDRIDKCALK
QISDQGVRVMLAPYAHE

Sequences:

>Translated_257_residues
MNKRNTQQRRHSIITILNELGEVSVDELSLRFETSEVTIRKDLAALEKTGLLLRRYGGAVAIPDEVTQQFSAKIAPNKLS
IAKTAAQLIKDHNRIIIDSGTTTSGLIEQLNDKRGLVVMTNALHLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVIVMVDSDKIGKRIPNLELPWAKVSVLVTDDRIDKCALK
QISDQGVRVMLAPYAHE
>Mature_257_residues
MNKRNTQQRRHSIITILNELGEVSVDELSLRFETSEVTIRKDLAALEKTGLLLRRYGGAVAIPDEVTQQFSAKIAPNKLS
IAKTAAQLIKDHNRIIIDSGTTTSGLIEQLNDKRGLVVMTNALHLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVIVMVDSDKIGKRIPNLELPWAKVSVLVTDDRIDKCALK
QISDQGVRVMLAPYAHE

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=40.9448818897638, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=40.1574803149606, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=30, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788069, Length=217, Percent_Identity=30.4147465437788, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=30.4347826086957, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=29.296875, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789829, Length=210, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082344, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787063, Length=225, Percent_Identity=25.3333333333333, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28501; Mature: 28501

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRNTQQRRHSIITILNELGEVSVDELSLRFETSEVTIRKDLAALEKTGLLLRRYGGAV
CCCCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCE
AIPDEVTQQFSAKIAPNKLSIAKTAAQLIKDHNRIIIDSGTTTSGLIEQLNDKRGLVVMT
ECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEE
NALHLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQVLRSYNFDQLFIGADGIDLER
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
GTTTFNELTGLSKVMAEVSREVIVMVDSDKIGKRIPNLELPWAKVSVLVTDDRIDKCALK
CCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCEEEEEEEECCCHHHHHHH
QISDQGVRVMLAPYAHE
HHCCCCCEEEECCCCCC
>Mature Secondary Structure
MNKRNTQQRRHSIITILNELGEVSVDELSLRFETSEVTIRKDLAALEKTGLLLRRYGGAV
CCCCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCE
AIPDEVTQQFSAKIAPNKLSIAKTAAQLIKDHNRIIIDSGTTTSGLIEQLNDKRGLVVMT
ECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEE
NALHLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQVLRSYNFDQLFIGADGIDLER
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
GTTTFNELTGLSKVMAEVSREVIVMVDSDKIGKRIPNLELPWAKVSVLVTDDRIDKCALK
CCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCEEEEEEEECCCHHHHHHH
QISDQGVRVMLAPYAHE
HHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]