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The map label for this gene is murB [H]

Identifier: 126176360

GI number: 126176360

Start: 4882463

End: 4883488

Strand: Reverse

Name: murB [H]

Synonym: Sbal_4175

Alternate gene names: 126176360

Gene position: 4883488-4882463 (Counterclockwise)

Preceding gene: 126176362

Following gene: 126176359

Centisome position: 95.24

GC content: 47.08

Gene sequence:

>1026_bases
ATGCCTCTAACTCATAGCCTTAAATCGTTTAATTCCTTTGGTTTAGCCCAGTCTTGCGCCGCTCTTGTTGAGGCGCACTC
AAAAGAAGCTGTTCAGGCGATGTGTTTGCCACTATGGCAACAGCAATTGCCTATGTTGGTGCTTGGTGGCGGTAGCAATC
TGGTCTTCACTGAGGACTTTAACGGTACAGTTGTCAGGATTTTATCGAAGGGGATAAAAGTATCTGAAGACGCAGAAGCG
TTTTATCTCGAGGTTGAGGCGGGTGAGAATTGGCACGAGTTAATTACGTTTACGCTCGAGCATGGCATGTTTGGGCTGGA
AAATATGGCGTTAATTCCTGGAACGGTTGGGGCTGCACCTATCCAGAATATTGGCGCTTATGGTGTTGAACTCTGTGATG
TATGTGATTGGGTTGAGTATCTTGATTTACCCTCAGGTGAGTTTGTGCGTATAAGCACTGCTGAGTGTCAATTTGCTTAC
CGTGAATCCATTTTCAAAGACAAATTACGCAATCTTGCCGTAGTTACAGCAGTCGGACTGCGTTTAGCTAAACGTTGGCA
ACCGCGTTTGGCCTATGGTCCACTGCAATCGTTTGATCCAGCAACCGTCACTGCGCGTGAAATTTTTAATCGCGTATGCC
AAGTTCGCAGTGAAAAGCTCCCCGATCCTGCTGTGCTCGGCAATGCAGGCAGTTTCTTTAAAAATCCTATTGTCAGCGCG
GCCTGTTATCTAGATTTAGCACAGCGTTTTCCGACGATAGTGGGTTACGCACAAGCAGATGCAACGGTGAAATTGGCGGC
AGGTTGGTTGATTGAACAAGCGGGACTGAAAGGTTTTGTGCTTGGTAATGCGGCTGTGCATGACAAACAAGCTTTGGTAT
TGGTGAATCGAGGCGGGGCAACGGGGCGTGATATTTGTCGCTTAGCACTGCATGTTATTGCGCAAGTACAGGATAAATTT
GATGTTGTGCTAGAAGCGGAACCTAGAATCATGGGCGCTAACGGTGAAGGAGATTTGTATGTCTGA

Upstream 100 bases:

>100_bases
CACTCCACGATGACTATTTCATCAATACGTGTCCTCCGCGTTAGCTGCAATCCTCGCTTTTAGCAGTTACAATGTGTTTT
TGTCGTCATTGATCAAACAC

Downstream 100 bases:

>100_bases
TAATTGGGGAAGAAAGCGCCAGATATTAGCGTTATTGTCTAGCGGTCAATTTGTTTCAGGCGAGCAGTTAGCCACTGAAC
TTGGGATTTCGCGCGCCGCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPLTHSLKSFNSFGLAQSCAALVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFTEDFNGTVVRILSKGIKVSEDAEA
FYLEVEAGENWHELITFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAECQFAY
RESIFKDKLRNLAVVTAVGLRLAKRWQPRLAYGPLQSFDPATVTAREIFNRVCQVRSEKLPDPAVLGNAGSFFKNPIVSA
ACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNRGGATGRDICRLALHVIAQVQDKF
DVVLEAEPRIMGANGEGDLYV

Sequences:

>Translated_341_residues
MPLTHSLKSFNSFGLAQSCAALVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFTEDFNGTVVRILSKGIKVSEDAEA
FYLEVEAGENWHELITFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAECQFAY
RESIFKDKLRNLAVVTAVGLRLAKRWQPRLAYGPLQSFDPATVTAREIFNRVCQVRSEKLPDPAVLGNAGSFFKNPIVSA
ACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNRGGATGRDICRLALHVIAQVQDKF
DVVLEAEPRIMGANGEGDLYV
>Mature_340_residues
PLTHSLKSFNSFGLAQSCAALVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFTEDFNGTVVRILSKGIKVSEDAEAF
YLEVEAGENWHELITFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAECQFAYR
ESIFKDKLRNLAVVTAVGLRLAKRWQPRLAYGPLQSFDPATVTAREIFNRVCQVRSEKLPDPAVLGNAGSFFKNPIVSAA
CYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNRGGATGRDICRLALHVIAQVQDKFD
VVLEAEPRIMGANGEGDLYV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=338, Percent_Identity=51.7751479289941, Blast_Score=353, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37062; Mature: 36931

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTHSLKSFNSFGLAQSCAALVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFTEDF
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECC
NGTVVRILSKGIKVSEDAEAFYLEVEAGENWHELITFTLEHGMFGLENMALIPGTVGAAP
CCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCC
IQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAECQFAYRESIFKDKLRNLAVVTAVGL
HHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAKRWQPRLAYGPLQSFDPATVTAREIFNRVCQVRSEKLPDPAVLGNAGSFFKNPIVSA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
ACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNRGGA
HHHHHHHHHCCHHEEEECCCCEEEEHHHHHHHHCCCCEEEECCCEECCCEEEEEEECCCC
TGRDICRLALHVIAQVQDKFDVVLEAEPRIMGANGEGDLYV
CHHHHHHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCC
>Mature Secondary Structure 
PLTHSLKSFNSFGLAQSCAALVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFTEDF
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECC
NGTVVRILSKGIKVSEDAEAFYLEVEAGENWHELITFTLEHGMFGLENMALIPGTVGAAP
CCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCC
IQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAECQFAYRESIFKDKLRNLAVVTAVGL
HHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAKRWQPRLAYGPLQSFDPATVTAREIFNRVCQVRSEKLPDPAVLGNAGSFFKNPIVSA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
ACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNRGGA
HHHHHHHHHCCHHEEEECCCCEEEEHHHHHHHHCCCCEEEECCCEECCCEEEEEEECCCC
TGRDICRLALHVIAQVQDKFDVVLEAEPRIMGANGEGDLYV
CHHHHHHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA