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The map label for this gene is cph2 [H]

Identifier: 126176093

GI number: 126176093

Start: 4579002

End: 4580888

Strand: Direct

Name: cph2 [H]

Synonym: Sbal_3903

Alternate gene names: 126176093

Gene position: 4579002-4580888 (Clockwise)

Preceding gene: 126176092

Following gene: 126176094

Centisome position: 89.3

GC content: 45.68

Gene sequence:

>1887_bases
ATGCTTAAACGAAACTCGTCACTCATACTCTTGCTGTGGCTATGGATGTGTTCAACACCTTCATTCGCAACCCTATTAAG
CATTGATGAATCAACGACGACACCGTTAAACCTTACGCCTTGGTTGATGGTGAGCCACCCAACTTCGGCGAAGGAATTTA
CCGAGATCCAAGCCTTGCCAAAAACGGATTGGCATAACTTCACCAATAAAGACATTCAAAAACTCAGCGGCCATGATTTT
TGGCTGAGTTTCAGCTTAACTAGCCCAGACGAAACACTTTCACGTATTTTAGCGTTAGATAACCCCTTGTTAGACAAAGT
GACTATCTACCATTTAGTCAATAATAAGCTCGCTAATACTGTGCTTATGGGCGACACCTTTCCCTATAACGAACGGCCAT
TTTTGAGCAATATCTTCCTGTATCCTTTTAAGCTCAACATGGATGATACCCATACTTTTTATTTGCATATTCAGACCGAA
GGCAGCGCTGCAATACCGTTAAATCTCTGGTCATCTAACGACTTAGCCCAGATTGCCGAATCCACTGCCGTCGAACATGG
TTTCCAACTCGGCGTACTTGCCGCGATTGGTATCTTTAGCCTCTTTATTGCCATTGCATCGGGCTCATTCAGTTACAGCT
ATTATTCTGGCTACGTCCTGAGCATGACCTTGCTCGTCGCTACCATCAACGGTTTTGCCTTTCGATTCCTCTGGCCAAAT
TGGCCGATATTACAGCAAGTTATGGTGCCATTTTTACTGCCAATCGTTATGGCGTTTGCGCTGATGTTTACCGAAAAAAT
ATTACAGCTCAAATATTTAAACCGCCGCATGCTGCTGACTTGTCGCTATAGCGCTGTGTATATCCTATGTATTGGACTCG
CCACGCCTTTTATCCAATATGGAACGGCGCTCTATATCGAGATCATTTCCGTTGCAGTGCTCAGCCTGGTACTTATGGTC
TTTGCCATTACTCAGGCTATCAATGGCCATAAACTGGCACGTATGTACACTATTGGCTGGGTGAGTATGCTGACAGGAGC
TTGCATCAGTAGCTTGTTGTATCTCAGCGTGATTGACCTCAATTTAAAACCGCAAACGCCTGTCATGCTCGGCCTGACGT
TTGAAATCATCTTTATGTCTCTGGTGCTTGCCATCCGCTATAACGATGAACGCAAAGCTAAGCTACGTATTCAGCAAGAG
GCCTTGAGGCAAGCACAGAAAATTCGCAGTGCGCGGGAAGAAGCCCTAAAAGCAGAAGCCGAGAGCAATGAGAAACTCGA
GCAAATGGTGCAAGAGCGCACCTTAGAACTTGAAATCACCCTCAGAGAATTGCATGAGGTGAACCAAAAGCTCACCGAAC
AAAGCACTATCGATAGCTTAACTGGGGTCAAAAACCGCAGTGCTTTCGATAAACGTTTGATCGCTGAAAGCCGGATCAGC
CGCAGGCAAGAAACACCCATAGCCCTGTTGATGCTCGATATCGATCGCTTCAAGCTGATCAACGATAGATTTGGCCATCT
TGCAGGCGATGAAGCCTTACGAACCATAGCCCAAACATTACAGCAACATTTAAAGCGGCCAACGGATCTCGTATCACGTT
ATGGAGGCGAGGAGTTTGCTATCATCCTGCCTAATACAGCAGAAGATGGTGCACTCCAAGTCGCTGAAACGATAAGAGAC
GCAGTTGCCTCTCTCCATTTCGAATGGGAAGGTGTGGCGATACCTTTGACTATCAGTATCGGAGTCAGTGCCGATATCGT
CACTAACGATCAGCACAGCACCAAATTATTAGAACAAGCGGATAAAGCCCTCTACCAAGCGAAAAATGGTGGACGTAATC
AAGTCAGCTTATTTTCATCAGTTCAAGCACGACCAGTACCTAATTAG

Upstream 100 bases:

>100_bases
ATCGCGAGTTATATTGCAAACTTGCGCGGTGAAAATGCTGATGAGTTTGCAGCGCGTTGCTACCAGAATAGCGTAGCTTT
TTTTAATTTGGACCGAGTCC

Downstream 100 bases:

>100_bases
GAGTCAAATGTGAATATCATTACCAGTGCCTTCCCTCAGCGTAGAATGCGCCGCATGCGTAAACATGATTTTAGCCGTCG
TCTTATGGCCGAAAATCAAC

Product: periplasmic/7TM domain sensor diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MLKRNSSLILLLWLWMCSTPSFATLLSIDESTTTPLNLTPWLMVSHPTSAKEFTEIQALPKTDWHNFTNKDIQKLSGHDF
WLSFSLTSPDETLSRILALDNPLLDKVTIYHLVNNKLANTVLMGDTFPYNERPFLSNIFLYPFKLNMDDTHTFYLHIQTE
GSAAIPLNLWSSNDLAQIAESTAVEHGFQLGVLAAIGIFSLFIAIASGSFSYSYYSGYVLSMTLLVATINGFAFRFLWPN
WPILQQVMVPFLLPIVMAFALMFTEKILQLKYLNRRMLLTCRYSAVYILCIGLATPFIQYGTALYIEIISVAVLSLVLMV
FAITQAINGHKLARMYTIGWVSMLTGACISSLLYLSVIDLNLKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKLRIQQE
ALRQAQKIRSAREEALKAEAESNEKLEQMVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLIAESRIS
RRQETPIALLMLDIDRFKLINDRFGHLAGDEALRTIAQTLQQHLKRPTDLVSRYGGEEFAIILPNTAEDGALQVAETIRD
AVASLHFEWEGVAIPLTISIGVSADIVTNDQHSTKLLEQADKALYQAKNGGRNQVSLFSSVQARPVPN

Sequences:

>Translated_628_residues
MLKRNSSLILLLWLWMCSTPSFATLLSIDESTTTPLNLTPWLMVSHPTSAKEFTEIQALPKTDWHNFTNKDIQKLSGHDF
WLSFSLTSPDETLSRILALDNPLLDKVTIYHLVNNKLANTVLMGDTFPYNERPFLSNIFLYPFKLNMDDTHTFYLHIQTE
GSAAIPLNLWSSNDLAQIAESTAVEHGFQLGVLAAIGIFSLFIAIASGSFSYSYYSGYVLSMTLLVATINGFAFRFLWPN
WPILQQVMVPFLLPIVMAFALMFTEKILQLKYLNRRMLLTCRYSAVYILCIGLATPFIQYGTALYIEIISVAVLSLVLMV
FAITQAINGHKLARMYTIGWVSMLTGACISSLLYLSVIDLNLKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKLRIQQE
ALRQAQKIRSAREEALKAEAESNEKLEQMVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLIAESRIS
RRQETPIALLMLDIDRFKLINDRFGHLAGDEALRTIAQTLQQHLKRPTDLVSRYGGEEFAIILPNTAEDGALQVAETIRD
AVASLHFEWEGVAIPLTISIGVSADIVTNDQHSTKLLEQADKALYQAKNGGRNQVSLFSSVQARPVPN
>Mature_628_residues
MLKRNSSLILLLWLWMCSTPSFATLLSIDESTTTPLNLTPWLMVSHPTSAKEFTEIQALPKTDWHNFTNKDIQKLSGHDF
WLSFSLTSPDETLSRILALDNPLLDKVTIYHLVNNKLANTVLMGDTFPYNERPFLSNIFLYPFKLNMDDTHTFYLHIQTE
GSAAIPLNLWSSNDLAQIAESTAVEHGFQLGVLAAIGIFSLFIAIASGSFSYSYYSGYVLSMTLLVATINGFAFRFLWPN
WPILQQVMVPFLLPIVMAFALMFTEKILQLKYLNRRMLLTCRYSAVYILCIGLATPFIQYGTALYIEIISVAVLSLVLMV
FAITQAINGHKLARMYTIGWVSMLTGACISSLLYLSVIDLNLKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKLRIQQE
ALRQAQKIRSAREEALKAEAESNEKLEQMVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLIAESRIS
RRQETPIALLMLDIDRFKLINDRFGHLAGDEALRTIAQTLQQHLKRPTDLVSRYGGEEFAIILPNTAEDGALQVAETIRD
AVASLHFEWEGVAIPLTISIGVSADIVTNDQHSTKLLEQADKALYQAKNGGRNQVSLFSSVQARPVPN

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=36.7231638418079, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=37.5, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=41.0112359550562, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=36.5168539325843, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI145693134, Length=184, Percent_Identity=38.5869565217391, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787802, Length=183, Percent_Identity=33.879781420765, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=36.8098159509202, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=34.5454545454545, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788085, Length=159, Percent_Identity=32.7044025157233, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=34.1614906832298, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787541, Length=177, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788956, Length=177, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=112, Percent_Identity=33.0357142857143, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 70796; Mature: 70796

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50007 PIPLC_X_DOMAIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRNSSLILLLWLWMCSTPSFATLLSIDESTTTPLNLTPWLMVSHPTSAKEFTEIQALP
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHCCC
KTDWHNFTNKDIQKLSGHDFWLSFSLTSPDETLSRILALDNPLLDKVTIYHLVNNKLANT
CCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCE
VLMGDTFPYNERPFLSNIFLYPFKLNMDDTHTFYLHIQTEGSAAIPLNLWSSNDLAQIAE
EEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCEEEEEEECCCCCHHHHHH
STAVEHGFQLGVLAAIGIFSLFIAIASGSFSYSYYSGYVLSMTLLVATINGFAFRFLWPN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEECCC
WPILQQVMVPFLLPIVMAFALMFTEKILQLKYLNRRMLLTCRYSAVYILCIGLATPFIQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHH
GTALYIEIISVAVLSLVLMVFAITQAINGHKLARMYTIGWVSMLTGACISSLLYLSVIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
NLKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKLRIQQEALRQAQKIRSAREEALKAEA
CCCCCCCEEEHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ESNEKLEQMVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLIAESRIS
CCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RRQETPIALLMLDIDRFKLINDRFGHLAGDEALRTIAQTLQQHLKRPTDLVSRYGGEEFA
HCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
IILPNTAEDGALQVAETIRDAVASLHFEWEGVAIPLTISIGVSADIVTNDQHSTKLLEQA
EEECCCCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEEECCEEEEEECCCHHHHHHHHH
DKALYQAKNGGRNQVSLFSSVQARPVPN
HHHHHHHCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLKRNSSLILLLWLWMCSTPSFATLLSIDESTTTPLNLTPWLMVSHPTSAKEFTEIQALP
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHCCC
KTDWHNFTNKDIQKLSGHDFWLSFSLTSPDETLSRILALDNPLLDKVTIYHLVNNKLANT
CCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCE
VLMGDTFPYNERPFLSNIFLYPFKLNMDDTHTFYLHIQTEGSAAIPLNLWSSNDLAQIAE
EEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCEEEEEEECCCCCHHHHHH
STAVEHGFQLGVLAAIGIFSLFIAIASGSFSYSYYSGYVLSMTLLVATINGFAFRFLWPN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEECCC
WPILQQVMVPFLLPIVMAFALMFTEKILQLKYLNRRMLLTCRYSAVYILCIGLATPFIQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHH
GTALYIEIISVAVLSLVLMVFAITQAINGHKLARMYTIGWVSMLTGACISSLLYLSVIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
NLKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKLRIQQEALRQAQKIRSAREEALKAEA
CCCCCCCEEEHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ESNEKLEQMVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLIAESRIS
CCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RRQETPIALLMLDIDRFKLINDRFGHLAGDEALRTIAQTLQQHLKRPTDLVSRYGGEEFA
HCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
IILPNTAEDGALQVAETIRDAVASLHFEWEGVAIPLTISIGVSADIVTNDQHSTKLLEQA
EEECCCCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEEECCEEEEEECCCHHHHHHHHH
DKALYQAKNGGRNQVSLFSSVQARPVPN
HHHHHHHCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]