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The map label for this gene is tatD [H]

Identifier: 126176092

GI number: 126176092

Start: 4578206

End: 4579009

Strand: Direct

Name: tatD [H]

Synonym: Sbal_3902

Alternate gene names: 126176092

Gene position: 4578206-4579009 (Clockwise)

Preceding gene: 126176091

Following gene: 126176093

Centisome position: 89.29

GC content: 49.13

Gene sequence:

>804_bases
ATGCCCTCATACATAGATATCGCTGTCAATTTACTTGGCAGCGCACTCGAGCCAGACACAGCATCGATAATACAAGCGGC
GGCGGGCCAAGGGGTTTCGCCGTTAATTGTTATTGGCAGCGATTTAACTGAAAGTGCAGCTGCCATCGCGATTTGCCAAC
AATATCCCAATCAACTTTATTGCACTGCTGGCGTACATCCTCACCATGCCAGTGGCTGGCAAGCTGACTCAAGCAAGCAA
CAAGCCGAACTCTGCCAAGCACCGCAAGTGGTTGCCGTTGGCGAATGTGGCTTAGACTACAATCGTGATTTCTCTCCTCG
CCCCATCCAGCGCCAAGCATTTATTGCCCAACTCGCCTTAGCCGTTGAACTGCAAATGCCCGTACTGATGCACGAACGCG
ATGCCCACGAAGACTTTATTGCTATCCTGCGGGAATATCGCCCACAGCTTAGTGGCGCACTTTTACATTGTTTCACTGGC
ACTCACGCCCAAATGGAAGCCTATATCGACCTCGATTTGCATTTAGGCATTACAGGCTGGGTTTGCGATGAAAGACGCGG
CCAAGAGTTAGCGCAACTCGTACCATTTATTCCGCAGAATCGCATTTTAATCGAAACCGATAGTCCGTACTTATTACCTC
GCAGCATGAGGCCTAAGCCTAAATCGAGTAAGAACAAGCCCGAATATCTCCCCTATATCGCGAGTTATATTGCAAACTTG
CGCGGTGAAAATGCTGATGAGTTTGCAGCGCGTTGCTACCAGAATAGCGTAGCTTTTTTTAATTTGGACCGAGTCCATGC
TTAA

Upstream 100 bases:

>100_bases
AGCAAGGCGAAAAAGTCTACATTGAAAAAGCAGCCCTAGGCTCTTTCTTAATGGGCACTGATGAGCGCAATGCCAAGGCA
CGGGTAAAACGCCTAAACTA

Downstream 100 bases:

>100_bases
ACGAAACTCGTCACTCATACTCTTGCTGTGGCTATGGATGTGTTCAACACCTTCATTCGCAACCCTATTAAGCATTGATG
AATCAACGACGACACCGTTA

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPSYIDIAVNLLGSALEPDTASIIQAAAGQGVSPLIVIGSDLTESAAAIAICQQYPNQLYCTAGVHPHHASGWQADSSKQ
QAELCQAPQVVAVGECGLDYNRDFSPRPIQRQAFIAQLALAVELQMPVLMHERDAHEDFIAILREYRPQLSGALLHCFTG
THAQMEAYIDLDLHLGITGWVCDERRGQELAQLVPFIPQNRILIETDSPYLLPRSMRPKPKSSKNKPEYLPYIASYIANL
RGENADEFAARCYQNSVAFFNLDRVHA

Sequences:

>Translated_267_residues
MPSYIDIAVNLLGSALEPDTASIIQAAAGQGVSPLIVIGSDLTESAAAIAICQQYPNQLYCTAGVHPHHASGWQADSSKQ
QAELCQAPQVVAVGECGLDYNRDFSPRPIQRQAFIAQLALAVELQMPVLMHERDAHEDFIAILREYRPQLSGALLHCFTG
THAQMEAYIDLDLHLGITGWVCDERRGQELAQLVPFIPQNRILIETDSPYLLPRSMRPKPKSSKNKPEYLPYIASYIANL
RGENADEFAARCYQNSVAFFNLDRVHA
>Mature_266_residues
PSYIDIAVNLLGSALEPDTASIIQAAAGQGVSPLIVIGSDLTESAAAIAICQQYPNQLYCTAGVHPHHASGWQADSSKQQ
AELCQAPQVVAVGECGLDYNRDFSPRPIQRQAFIAQLALAVELQMPVLMHERDAHEDFIAILREYRPQLSGALLHCFTGT
HAQMEAYIDLDLHLGITGWVCDERRGQELAQLVPFIPQNRILIETDSPYLLPRSMRPKPKSSKNKPEYLPYIASYIANLR
GENADEFAARCYQNSVAFFNLDRVHA

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=293, Percent_Identity=26.6211604095563, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI225903439, Length=250, Percent_Identity=27.2, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225903424, Length=162, Percent_Identity=35.1851851851852, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI110349734, Length=176, Percent_Identity=31.25, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI110349730, Length=176, Percent_Identity=31.25, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226061853, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=48.4496124031008, Blast_Score=258, Evalue=2e-70,
Organism=Escherichia coli, GI1787342, Length=250, Percent_Identity=30, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=28.3524904214559, Blast_Score=94, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=32.8571428571429, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71980746, Length=275, Percent_Identity=26.9090909090909, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=170, Percent_Identity=36.4705882352941, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543026, Length=175, Percent_Identity=33.7142857142857, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648690, Length=282, Percent_Identity=31.5602836879433, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI221330018, Length=299, Percent_Identity=28.7625418060201, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24586117, Length=275, Percent_Identity=29.0909090909091, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29515; Mature: 29384

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYIDIAVNLLGSALEPDTASIIQAAAGQGVSPLIVIGSDLTESAAAIAICQQYPNQLY
CCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
CTAGVHPHHASGWQADSSKQQAELCQAPQVVAVGECGLDYNRDFSPRPIQRQAFIAQLAL
EECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
AVELQMPVLMHERDAHEDFIAILREYRPQLSGALLHCFTGTHAQMEAYIDLDLHLGITGW
HHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEEEEECCEEE
VCDERRGQELAQLVPFIPQNRILIETDSPYLLPRSMRPKPKSSKNKPEYLPYIASYIANL
EECCHHHHHHHHHCCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGENADEFAARCYQNSVAFFNLDRVHA
CCCCHHHHHHHHHHCCEEEEECCCCCC
>Mature Secondary Structure 
PSYIDIAVNLLGSALEPDTASIIQAAAGQGVSPLIVIGSDLTESAAAIAICQQYPNQLY
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
CTAGVHPHHASGWQADSSKQQAELCQAPQVVAVGECGLDYNRDFSPRPIQRQAFIAQLAL
EECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
AVELQMPVLMHERDAHEDFIAILREYRPQLSGALLHCFTGTHAQMEAYIDLDLHLGITGW
HHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEEEEECCEEE
VCDERRGQELAQLVPFIPQNRILIETDSPYLLPRSMRPKPKSSKNKPEYLPYIASYIANL
EECCHHHHHHHHHCCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGENADEFAARCYQNSVAFFNLDRVHA
CCCCHHHHHHHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]