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The map label for this gene is trpD

Identifier: 126174911

GI number: 126174911

Start: 3169784

End: 3170857

Strand: Direct

Name: trpD

Synonym: Sbal_2703

Alternate gene names: 126174911

Gene position: 3169784-3170857 (Clockwise)

Preceding gene: 126174910

Following gene: 126174912

Centisome position: 61.82

GC content: 51.21

Gene sequence:

>1074_bases
ATGAGTACCAACCCTATTCAGCCTTTACTCGACGTTTTATACCAAGGTAAAAGTTTAAGCCGCGAGCAAACCGCCGAACT
TTTTGGCGCGTTAATTCGCGGAGAGATGAGTGAAGCGGCAATGGCGGGAATGTTAGTTGCGCTGAAAATGCGCGGTGAGA
CCATTGATGAGATCAGCGGCGCCGCCGATGCTATGCGCGCCGCTGCCAAACCTTTTCCTTGCCCTGAGCGAAACAACAAT
CCGCTTCATAATGGCATAGTTGATATTGTTGGCACGGGTGGCGATGGCTTTAATACCATTAATATTTCCACCACTGCGGC
CTTTGTTGCCGCGGCGGCAGGCGCTAAGGTCGCCAAACACGGCAATCGTAGCGTGTCGAGTAAATCGGGTTCATCGGACC
TCTTGGCGCAATTTGGCATCGACTTAACTATGTCGCCAGAGACTGCCAGTCGTTGCCTCGACGCATTGAATCTGTGCTTT
TTATTTGCGCCACACTACCATGGCGGGGTAAAACATGCGGTGCCCGTAAGACAAGCACTGAAAACGCGCACCTTATTCAA
TGTGTTAGGGCCGCTTATCAACCCTGCAAGGCCTGAGTTTATGCTACTTGGCGTGTATAGCCCTGAGTTAGTCTTACCGA
TAGCGAAAGTATTAAAGGCGCTTGGCACAAAACGCGCTATGGTAGTGCACGGCAGCGGTTTAGATGAAGTCGCGCTGCAC
GGCAACACCCAAGTTGCTGAGTTAAAAGACGGCGACATCATAGAGTATCAACTCACGCCCGCCGATTTAGGCGTGCCTTT
AGCGCAAATATCAGACTTAGAAGGGGGCGAGCCCGCGCAGAATGCCTTGATTACCGAGGCGATTTTAAAAGGCCGTGGCA
CTGAAGCACACGCCAATGCGGTCGCCATCAATGCCGGCTGTGCTTTATATGTCTGTGGAATTACTGATTCAGTCAAAGCC
GGAACCTTACTTGCGCTCGCTACCATTCAAAGCGGCAAAGCCTTTGAATTGTTAAGCCAGCTCGCAAAAGTCAGCGGTGA
AGCCCTAGTCAACGGTCAAGAAAGAGGAAGATAA

Upstream 100 bases:

>100_bases
TTCTCACCACCTTAGGTAGCACACTGCTCATTCAAACCTTGGCCTTTCTTACCCAAGAGATGACATTTCTACCCCAAGAC
ATGACAACAGGAGTAACCGC

Downstream 100 bases:

>100_bases
GCGAATGTCTCAAGTAGAAGTGACTCCAACAGCAATGACTCAAGACCTGCGTACTCAGCCAGAGGCAGCCACAAACGCTA
TGCCAAAAAGTAATGTGTTA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSTNPIQPLLDVLYQGKSLSREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISGAADAMRAAAKPFPCPERNNN
PLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCF
LFAPHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALH
GNTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGRGTEAHANAVAINAGCALYVCGITDSVKA
GTLLALATIQSGKAFELLSQLAKVSGEALVNGQERGR

Sequences:

>Translated_357_residues
MSTNPIQPLLDVLYQGKSLSREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISGAADAMRAAAKPFPCPERNNN
PLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCF
LFAPHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALH
GNTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGRGTEAHANAVAINAGCALYVCGITDSVKA
GTLLALATIQSGKAFELLSQLAKVSGEALVNGQERGR
>Mature_356_residues
STNPIQPLLDVLYQGKSLSREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISGAADAMRAAAKPFPCPERNNNP
LHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCFL
FAPHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALHG
NTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGRGTEAHANAVAINAGCALYVCGITDSVKAG
TLLALATIQSGKAFELLSQLAKVSGEALVNGQERGR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=339, Percent_Identity=53.6873156342183, Blast_Score=318, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6320561, Length=289, Percent_Identity=33.5640138408304, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SHEB5 (A3D628)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001051060.1
- ProteinModelPortal:   A3D628
- SMR:   A3D628
- STRING:   A3D628
- GeneID:   4843376
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_2703
- NMPDR:   fig|325240.3.peg.1875
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   A3D628
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37226; Mature: 37095

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPIQPLLDVLYQGKSLSREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISG
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
AADAMRAAAKPFPCPERNNNPLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKH
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCHHHHC
GNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCFLFAPHYHGGVKHAVPVRQAL
CCCCCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALH
HHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEC
GNTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGRGTEAHANA
CCCEEEECCCCCEEEEEECHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
VAINAGCALYVCGITDSVKAGTLLALATIQSGKAFELLSQLAKVSGEALVNGQERGR
EEEECCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHEECCHHCCC
>Mature Secondary Structure 
STNPIQPLLDVLYQGKSLSREQTAELFGALIRGEMSEAAMAGMLVALKMRGETIDEISG
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
AADAMRAAAKPFPCPERNNNPLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKH
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCHHHHC
GNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCFLFAPHYHGGVKHAVPVRQAL
CCCCCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALH
HHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEC
GNTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGRGTEAHANA
CCCEEEECCCCCEEEEEECHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
VAINAGCALYVCGITDSVKAGTLLALATIQSGKAFELLSQLAKVSGEALVNGQERGR
EEEECCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA