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The map label for this gene is fabA

Identifier: 126174778

GI number: 126174778

Start: 3007900

End: 3008415

Strand: Direct

Name: fabA

Synonym: Sbal_2565

Alternate gene names: 126174778

Gene position: 3007900-3008415 (Clockwise)

Preceding gene: 126174777

Following gene: 126174794

Centisome position: 58.66

GC content: 44.96

Gene sequence:

>516_bases
ATGAATAAAGCAAACAGTTTCAATAAAGAAGAACTCATCGCCTGTGGCCATGGGAAATTATTTGGTCCAAATTCACCTCG
TCTGCCTGTCGATAACATGCTGATGATGGATAGAATCGTCACTATCAATGATAATGGCGGCGAGTTTGGCAAAGGTGAAA
TTGTCGCTGAACTCGATATTAATCCAGACTTATGGTTTTTTGACTGCCACTTCATTACCGATCCCGTAATGCCAGGCTGT
TTAGGCCTAGATGCCATGTGGCAACTCGTGGGCTTCTATTTAGGCTGGGAAGGCGCTGAAGGTAAAGGACGTGCACTGGG
TGTAGGTGAAGTGAAGTTTACCGGCCAAGTATTACCAGGCGCGAAGAAAGTCACTTACAAGCTCAATATCAAGCGTACCA
TTCACCGTAAACTGGTGATGGGTATTGCCGATGCAATCCTAGAAGTGGATGGCCGTCAAATCTACAGTGCAACCGATCTT
AAAGTTGGTGTCTTTAGCGATACCTCTACATTCTAA

Upstream 100 bases:

>100_bases
CAAAATTGGGATTTTTTCGCCGCTAATTAGCTGATCGGAGTTGTTTAGCTTACACGTGTTCGCTAACCTTGGCGGCTCTT
ATTGCTGGAGTAGTAAAACA

Downstream 100 bases:

>100_bases
TCCGTCTGACTCCAAAACACTGAAGCTATAAGTACTGCAGATATAAAAATGCCCTCATCTGAGGGCAATATGCTGCATTA
CTTTGCTTGTTCTGGACTAT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDINPDLWFFDCHFITDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF

Sequences:

>Translated_171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDINPDLWFFDCHFITDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF
>Mature_171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDINPDLWFFDCHFITDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=69.0058479532164, Blast_Score=254, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_SHEB2 (B8E711)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002357707.1
- ProteinModelPortal:   B8E711
- SMR:   B8E711
- GeneID:   7088313
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_1779
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 18784; Mature: 18784

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: ACT_SITE 70-70

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDI
CCCCCCCCCCCEEEECCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFDCHFITDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
CEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDI
CCCCCCCCCCCEEEECCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFDCHFITDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
CEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA