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The map label for this gene is dxs [C]

Identifier: 126174437

GI number: 126174437

Start: 2569647

End: 2570624

Strand: Reverse

Name: dxs [C]

Synonym: Sbal_2221

Alternate gene names: 126174437

Gene position: 2570624-2569647 (Counterclockwise)

Preceding gene: 126174438

Following gene: 126174436

Centisome position: 50.14

GC content: 49.49

Gene sequence:

>978_bases
GTGGCTGAAATGAATATGTTACAGGCCGTCAATGAGGCCTTGTCGATCGCCATGCAAGCCGATGAGCGCATGGTGGTTTT
TGGTGAAGATGTGGGTCACTTTGGTGGGGTATTTCGCGCCACTTCCGGTCTTCAAGAAAAATTCGGTCGTGATCGCTGCT
TTAATACTCCGCTGACAGAGCAAGGTATTGCCGGTTTTGCCAATGGTTTAGCCTCAAATGGCATGACTGCTGTGGCTGAA
ATCCAATTCGCCGATTATATCTTTCCGGCGTTTGATCAAATCGTCAACGAGTCGGCTAAGTTCCGTTACCGTAGCGGTAA
TGAGTTCGATGTCGGTGGATTAGTGTTCCGTACGCCCTATGGCGGCGGTATCGCGGGCGGACATTATCACTCACAATCAC
CCGAAGCTTATTTTACCCAGACGCCGGGGTTAAAAGTCGTTGTGCCACGCAACCCAGAGCAAGCCAAAGGCCTGCTATTG
GCGTCAATTCGTGACAAAAACCCGGTGATCTTCTTTGAGCCTAAGCGTTTATATCGCGCATCGGTTGGCGAAGTACCAGC
GGGCGATTATGAAATTGAACTGGGCAAGGCTGAAGTGGTTCGCGAAGGTAAAGACATCACCTTAGTGGCGTGGGGCGCGC
AAATGGAAATCCTTGAAAAAGCCGCCGACATGGCCGCTAAAGAAGGGATCTCCTGCGAAATTATTGATTTACGCACCTTG
TCACCTTGGGATATCGATACCGTTGCCGATTCAGTTAAAAAGACTGGACGTTTGCTGGTTAACCATGAAGCGCCATTAAC
CGGTGGTTTTGCCGGTGAAATTGCCGCGACAATCCAGCAAGAATGCTTCTTGTATCTAGAGTCGCCCATCAGCCGCGTTT
GTGGTTTAGATACCCCGTACCCACTCATTCATGAAAAAGAATACATGCCTGATGCGTTCAAAACGTTTGAAGCCATCAAA
GCATCAGTGACCTTCTAG

Upstream 100 bases:

>100_bases
CAAGCCGACGCCAGTGCTGAGAAAGCAACTCGCCGATCTTAAAGAACATATCAAAAAATATCCGCAAGCCTATCCAAAAA
GTGCAGGGAGACTATAAGCC

Downstream 100 bases:

>100_bases
GAGTCCGGTATGATTAAAGATTTTATTTTGCCGGATATTGGCGAAGGTGTAGTGGAGTGTGAATTGGTTGAATGGTTGGT
CAAAGAAGGCGACACAGTCG

Product: transketolase central region

Products: NA

Alternate protein names: Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAEMNMLQAVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLL
ASIRDKNPVIFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMAAKEGISCEIIDLRTL
SPWDIDTVADSVKKTGRLLVNHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLIHEKEYMPDAFKTFEAIK
ASVTF

Sequences:

>Translated_325_residues
MAEMNMLQAVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLL
ASIRDKNPVIFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMAAKEGISCEIIDLRTL
SPWDIDTVADSVKKTGRLLVNHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLIHEKEYMPDAFKTFEAIK
ASVTF
>Mature_324_residues
AEMNMLQAVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAEI
QFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLA
SIRDKNPVIFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMAAKEGISCEIIDLRTLS
PWDIDTVADSVKKTGRLLVNHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLIHEKEYMPDAFKTFEAIKA
SVTF

Specific function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components:branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltran

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=324, Percent_Identity=60.8024691358025, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI34101272, Length=324, Percent_Identity=60.8024691358025, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI156564403, Length=329, Percent_Identity=34.3465045592705, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI291084858, Length=329, Percent_Identity=32.5227963525836, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17506935, Length=325, Percent_Identity=61.8461538461539, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17538422, Length=328, Percent_Identity=36.5853658536585, Blast_Score=204, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6319698, Length=324, Percent_Identity=35.4938271604938, Blast_Score=198, Evalue=1e-51,
Organism=Drosophila melanogaster, GI160714828, Length=324, Percent_Identity=57.7160493827161, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI160714832, Length=324, Percent_Identity=57.7160493827161, Blast_Score=396, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21358145, Length=303, Percent_Identity=37.2937293729373, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24650940, Length=303, Percent_Identity=37.2937293729373, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI160714826, Length=65, Percent_Identity=52.3076923076923, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650943, Length=91, Percent_Identity=34.0659340659341, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650945, Length=91, Percent_Identity=34.0659340659341, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.4 [H]

Molecular weight: Translated: 35526; Mature: 35395

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEMNMLQAVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTE
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHCHHHHHHHHHHHHHCCCCCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLASIRDKNPVIFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMAAKEGISCEIIDLRTL
CCCCCCCCCEEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECC
SPWDIDTVADSVKKTGRLLVNHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLIHEKEYMPDAFKTFEAIKASVTF
CCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEMNMLQAVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTE
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHCHHHHHHHHHHHHHCCCCCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLASIRDKNPVIFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMAAKEGISCEIIDLRTL
CCCCCCCCCEEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECC
SPWDIDTVADSVKKTGRLLVNHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLIHEKEYMPDAFKTFEAIKASVTF
CCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA