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The map label for this gene is polB [H]

Identifier: 126173864

GI number: 126173864

Start: 1902147

End: 1904576

Strand: Direct

Name: polB [H]

Synonym: Sbal_1630

Alternate gene names: 126173864

Gene position: 1902147-1904576 (Clockwise)

Preceding gene: 126173857

Following gene: 126173865

Centisome position: 37.1

GC content: 47.49

Gene sequence:

>2430_bases
ATGAAGCCTAAGGCAACAACGGCCGTTAGTGTACAAGGTCGAGTCTTAACACGCCATGCGATTCATCGTCATGGGAGTTT
AGTGTTGCAGTATTATCTGGCGACCGCCCAAGGCCCTGTGCTGGTGGAAGTGCAAGGCACCGAACACATTTGTTTTTGTC
ATCAAACGGATGTGGCGGCTCTACAGTTACAAACGCCGGGTCAAGCATTGCGGTTTGTGCCGTTAGCGCTCAAAAGCTTT
AAAGGCGGCTCCGTCAGTGGAGTTTATGCTAAATCGAGCAACAGCTTACGTACCTTACAGCGCATCGCAAAAGATGCCGA
CATTCCCTTATTTGAAGCGGATATTCGGCCCGAACAGCGTTATTTAATCGAGCGGTTTGTGGCGCTGGATGTGGCATTTT
TAGGGCATTTCTCTGCGCCGACTAGCGACAGTCTTGAGGCTAACTCGTTGCCGGTGTTTATCGCCGAGCGGGCTAAGAGT
ATTGCCCCTTTAACGGCGGTGAATTTACGCTGTATCTCACTGGATTTTGAATGCAGCTTTGAGGGCTTACTCTATTCGGT
GGCGCTATATGGTCAAGACAGTGGCCGAGACGAGGGGCAAGGCAGCCTCAAGCAGACTTATGAAAAAGTGATTATGGTGG
GCGAAGTTGAATCAAACGCCCCCGATTATATCGAATGGGTGGCCGATGAAGCTGCGCTGATCCATCGATTAATCGCGTGG
TTCCATGAGTTTGATCCTGACTTTATTATCGGTTGGTCAGTGGTGAGTTTCGATCTCGCGCTGTTGTCACGCCGTGCATT
ATTACACCGTATTCCGCTCACTATTGGCCGCGGTGGCGCTAAGCTCGATTGGAAAGTTGACAATAAGTTTCGCCCAGAAA
CCTTAGTCTTACCGGGCCGTGTGGTACTCGATGGTATCGATTGGCTTAAAGCCGCTTTTTATCACTTTGAGCGTTTCTCG
TTGGAATTTGTGTCGCGGCAACTATTAGGTGAAGGCAAGGCCATTCATAACGTCGATAATCGCGTTGAAGAAATTGACCA
GCTGTTTAAGACCGATAAACAAGCCTTAGCGCATTATAATCTTACCGATAGCCGCCTAGTATGGGATATTTTTACTCACA
CTCAATTGTGGGATTTTGCCCTCGCGCGTGCCGAACTGACAGGTTTAGAACTGGGACGGGTAGGGGCTTCGGTGGCGGCG
TTTAATCATTTGTATTTACCACATTTACATCGCGCGGGTTATGTCGCTCCAGCAGAGCCTGTGAGTCAGGGCATTGAAAG
TCCTGGTGGTTACGTGATGGATTCTGTGCCGGGTCTTTATAAACACATCTTAGTGTTCGATTTTAAAAGTCTGTATCCCT
CCATTATTCGCACCTTTTTGATCGACCCTAAGGGATTGATTGAAGGCTTGCAGTTGCCCGAGTCTGAATGTGTTGCGGGG
TTTCTCGGTGGCCGTTTCAGTCGGCAACAGCCTATTTTACCTAAGCTAATTCAAACCTTATCTGAGCAGCGCGAAAAGGC
TAAGCGTGAGCACAATGCGCCGTTATCCCAAGCGATAAAAATTATCATGAACTCGCTGTATGGGGTTTTAGGCTCTCAAG
GCTGCGTGTTCCATGATGCCAAGTTGGCAAGTTCGATCACGATGCGCGGCCATCAAATCATGAAACAAACCCGCGCATGG
ATAGAAGAGATGGGCTATCAAGTGATTTACGGCGATACGGATTCGACCTTTGTGTGGCTTGGCAGCGAGCCTGATCTATC
AGACATTAACGCCTTAGGTAACACTCTGGCGCAGGATATCAATGCTAAGTGGCAGGCTAAGATCTGTGCTGATCACCAAG
TTGAGAGTTTTCTCGAGTTACAGTTTGAGCGGCATTACGAGCAGTTCTTTATGCCAACCTTAAGAGGCTCATTAGAAGGC
AGTAAAAAACGTTATGTTGGCGCGTGGCGCAATGCGAGCGATGAACTTGAGCTCACCTTTAGAGGTATGGAACAAGTGCG
TAGTGATTGGAGCCCCTTAGCGCGCAAAGTCCAAGAGTCACTCTATGAGCGAATGTTTAACCAAAGGGATATCAGTATTT
ATTTAGCCAGCGTGTTTGAAAAACTGCTTGATGGTCAGTTGGATAATGATTTGGTATTTCGTAAACGCATGCGGCGCAAT
ATTGAAGATTACACGGCTAAATCTTCACCACATGTTAAAGTCGCCCAGCAACTATGCGGCCTAACAGGTGATGTCTCTTT
TGGCAAGCGTGGGGCGCAAATTGACTACCTGATTACTGTAAATGGACCGGAACCCTTACTGTACAGAACGTCACCAATTG
ATTACCAATACTACATTGATAAGCAAATTGGCCCTATTGCAGAACCGGTATTTTCGATAATGAAACTAAACTACATGGAT
ATTGCGTCAAAGCAGTTGCTGTTAATTTAG

Upstream 100 bases:

>100_bases
TAATGCTGTACATAATAACAGTGATTGCATAGCCTAAGAAACTTTTCTGCCATTTGGCGGCATTTAAATTGAGTAGCTAT
ACGATTTGGGAACCCATGCG

Downstream 100 bases:

>100_bases
TGTTTTTAATGTTCCTTATGTGTTGCGATAGGTGGCGAATGTAGCGTTTTAACCTGTTTTGTAGAGGTTAACTGGTTTGT
TTTTGTGATGTTAATCGACA

Product: DNA polymerase II

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 809; Mature: 809

Protein sequence:

>809_residues
MKPKATTAVSVQGRVLTRHAIHRHGSLVLQYYLATAQGPVLVEVQGTEHICFCHQTDVAALQLQTPGQALRFVPLALKSF
KGGSVSGVYAKSSNSLRTLQRIAKDADIPLFEADIRPEQRYLIERFVALDVAFLGHFSAPTSDSLEANSLPVFIAERAKS
IAPLTAVNLRCISLDFECSFEGLLYSVALYGQDSGRDEGQGSLKQTYEKVIMVGEVESNAPDYIEWVADEAALIHRLIAW
FHEFDPDFIIGWSVVSFDLALLSRRALLHRIPLTIGRGGAKLDWKVDNKFRPETLVLPGRVVLDGIDWLKAAFYHFERFS
LEFVSRQLLGEGKAIHNVDNRVEEIDQLFKTDKQALAHYNLTDSRLVWDIFTHTQLWDFALARAELTGLELGRVGASVAA
FNHLYLPHLHRAGYVAPAEPVSQGIESPGGYVMDSVPGLYKHILVFDFKSLYPSIIRTFLIDPKGLIEGLQLPESECVAG
FLGGRFSRQQPILPKLIQTLSEQREKAKREHNAPLSQAIKIIMNSLYGVLGSQGCVFHDAKLASSITMRGHQIMKQTRAW
IEEMGYQVIYGDTDSTFVWLGSEPDLSDINALGNTLAQDINAKWQAKICADHQVESFLELQFERHYEQFFMPTLRGSLEG
SKKRYVGAWRNASDELELTFRGMEQVRSDWSPLARKVQESLYERMFNQRDISIYLASVFEKLLDGQLDNDLVFRKRMRRN
IEDYTAKSSPHVKVAQQLCGLTGDVSFGKRGAQIDYLITVNGPEPLLYRTSPIDYQYYIDKQIGPIAEPVFSIMKLNYMD
IASKQLLLI

Sequences:

>Translated_809_residues
MKPKATTAVSVQGRVLTRHAIHRHGSLVLQYYLATAQGPVLVEVQGTEHICFCHQTDVAALQLQTPGQALRFVPLALKSF
KGGSVSGVYAKSSNSLRTLQRIAKDADIPLFEADIRPEQRYLIERFVALDVAFLGHFSAPTSDSLEANSLPVFIAERAKS
IAPLTAVNLRCISLDFECSFEGLLYSVALYGQDSGRDEGQGSLKQTYEKVIMVGEVESNAPDYIEWVADEAALIHRLIAW
FHEFDPDFIIGWSVVSFDLALLSRRALLHRIPLTIGRGGAKLDWKVDNKFRPETLVLPGRVVLDGIDWLKAAFYHFERFS
LEFVSRQLLGEGKAIHNVDNRVEEIDQLFKTDKQALAHYNLTDSRLVWDIFTHTQLWDFALARAELTGLELGRVGASVAA
FNHLYLPHLHRAGYVAPAEPVSQGIESPGGYVMDSVPGLYKHILVFDFKSLYPSIIRTFLIDPKGLIEGLQLPESECVAG
FLGGRFSRQQPILPKLIQTLSEQREKAKREHNAPLSQAIKIIMNSLYGVLGSQGCVFHDAKLASSITMRGHQIMKQTRAW
IEEMGYQVIYGDTDSTFVWLGSEPDLSDINALGNTLAQDINAKWQAKICADHQVESFLELQFERHYEQFFMPTLRGSLEG
SKKRYVGAWRNASDELELTFRGMEQVRSDWSPLARKVQESLYERMFNQRDISIYLASVFEKLLDGQLDNDLVFRKRMRRN
IEDYTAKSSPHVKVAQQLCGLTGDVSFGKRGAQIDYLITVNGPEPLLYRTSPIDYQYYIDKQIGPIAEPVFSIMKLNYMD
IASKQLLLI
>Mature_809_residues
MKPKATTAVSVQGRVLTRHAIHRHGSLVLQYYLATAQGPVLVEVQGTEHICFCHQTDVAALQLQTPGQALRFVPLALKSF
KGGSVSGVYAKSSNSLRTLQRIAKDADIPLFEADIRPEQRYLIERFVALDVAFLGHFSAPTSDSLEANSLPVFIAERAKS
IAPLTAVNLRCISLDFECSFEGLLYSVALYGQDSGRDEGQGSLKQTYEKVIMVGEVESNAPDYIEWVADEAALIHRLIAW
FHEFDPDFIIGWSVVSFDLALLSRRALLHRIPLTIGRGGAKLDWKVDNKFRPETLVLPGRVVLDGIDWLKAAFYHFERFS
LEFVSRQLLGEGKAIHNVDNRVEEIDQLFKTDKQALAHYNLTDSRLVWDIFTHTQLWDFALARAELTGLELGRVGASVAA
FNHLYLPHLHRAGYVAPAEPVSQGIESPGGYVMDSVPGLYKHILVFDFKSLYPSIIRTFLIDPKGLIEGLQLPESECVAG
FLGGRFSRQQPILPKLIQTLSEQREKAKREHNAPLSQAIKIIMNSLYGVLGSQGCVFHDAKLASSITMRGHQIMKQTRAW
IEEMGYQVIYGDTDSTFVWLGSEPDLSDINALGNTLAQDINAKWQAKICADHQVESFLELQFERHYEQFFMPTLRGSLEG
SKKRYVGAWRNASDELELTFRGMEQVRSDWSPLARKVQESLYERMFNQRDISIYLASVFEKLLDGQLDNDLVFRKRMRRN
IEDYTAKSSPHVKVAQQLCGLTGDVSFGKRGAQIDYLITVNGPEPLLYRTSPIDYQYYIDKQIGPIAEPVFSIMKLNYMD
IASKQLLLI

Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=631, Percent_Identity=26.7828843106181, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI106507301, Length=657, Percent_Identity=25.5707762557078, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI153792012, Length=690, Percent_Identity=22.3188405797101, Blast_Score=82, Evalue=3e-15,
Organism=Escherichia coli, GI1786246, Length=812, Percent_Identity=42.487684729064, Blast_Score=618, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI32565317, Length=628, Percent_Identity=25, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17559488, Length=713, Percent_Identity=23.2819074333801, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320101, Length=632, Percent_Identity=24.5253164556962, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324227, Length=540, Percent_Identity=22.5925925925926, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24648780, Length=638, Percent_Identity=22.5705329153605, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24664937, Length=646, Percent_Identity=25.5417956656347, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 91158; Mature: 91158

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00116 DNA_POLYMERASE_B ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKATTAVSVQGRVLTRHAIHRHGSLVLQYYLATAQGPVLVEVQGTEHICFCHQTDVAA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCEE
LQLQTPGQALRFVPLALKSFKGGSVSGVYAKSSNSLRTLQRIAKDADIPLFEADIRPEQR
EEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHH
YLIERFVALDVAFLGHFSAPTSDSLEANSLPVFIAERAKSIAPLTAVNLRCISLDFECSF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHCCCCCEEEEEEEEEEEECCCCC
EGLLYSVALYGQDSGRDEGQGSLKQTYEKVIMVGEVESNAPDYIEWVADEAALIHRLIAW
CHHEEEEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FHEFDPDFIIGWSVVSFDLALLSRRALLHRIPLTIGRGGAKLDWKVDNKFRPETLVLPGR
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCEEEECCH
VVLDGIDWLKAAFYHFERFSLEFVSRQLLGEGKAIHNVDNRVEEIDQLFKTDKQALAHYN
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTDSRLVWDIFTHTQLWDFALARAELTGLELGRVGASVAAFNHLYLPHLHRAGYVAPAEP
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHH
VSQGIESPGGYVMDSVPGLYKHILVFDFKSLYPSIIRTFLIDPKGLIEGLQLPESECVAG
HHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
FLGGRFSRQQPILPKLIQTLSEQREKAKREHNAPLSQAIKIIMNSLYGVLGSQGCVFHDA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEHH
KLASSITMRGHQIMKQTRAWIEEMGYQVIYGDTDSTFVWLGSEPDLSDINALGNTLAQDI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHC
NAKWQAKICADHQVESFLELQFERHYEQFFMPTLRGSLEGSKKRYVGAWRNASDELELTF
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCCEEEHH
RGMEQVRSDWSPLARKVQESLYERMFNQRDISIYLASVFEKLLDGQLDNDLVFRKRMRRN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
IEDYTAKSSPHVKVAQQLCGLTGDVSFGKRGAQIDYLITVNGPEPLLYRTSPIDYQYYID
HHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCEEEEEC
KQIGPIAEPVFSIMKLNYMDIASKQLLLI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MKPKATTAVSVQGRVLTRHAIHRHGSLVLQYYLATAQGPVLVEVQGTEHICFCHQTDVAA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCEE
LQLQTPGQALRFVPLALKSFKGGSVSGVYAKSSNSLRTLQRIAKDADIPLFEADIRPEQR
EEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHH
YLIERFVALDVAFLGHFSAPTSDSLEANSLPVFIAERAKSIAPLTAVNLRCISLDFECSF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHCCCCCEEEEEEEEEEEECCCCC
EGLLYSVALYGQDSGRDEGQGSLKQTYEKVIMVGEVESNAPDYIEWVADEAALIHRLIAW
CHHEEEEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FHEFDPDFIIGWSVVSFDLALLSRRALLHRIPLTIGRGGAKLDWKVDNKFRPETLVLPGR
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCEEEECCH
VVLDGIDWLKAAFYHFERFSLEFVSRQLLGEGKAIHNVDNRVEEIDQLFKTDKQALAHYN
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTDSRLVWDIFTHTQLWDFALARAELTGLELGRVGASVAAFNHLYLPHLHRAGYVAPAEP
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHH
VSQGIESPGGYVMDSVPGLYKHILVFDFKSLYPSIIRTFLIDPKGLIEGLQLPESECVAG
HHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
FLGGRFSRQQPILPKLIQTLSEQREKAKREHNAPLSQAIKIIMNSLYGVLGSQGCVFHDA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEHH
KLASSITMRGHQIMKQTRAWIEEMGYQVIYGDTDSTFVWLGSEPDLSDINALGNTLAQDI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHC
NAKWQAKICADHQVESFLELQFERHYEQFFMPTLRGSLEGSKKRYVGAWRNASDELELTF
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCCEEEHH
RGMEQVRSDWSPLARKVQESLYERMFNQRDISIYLASVFEKLLDGQLDNDLVFRKRMRRN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
IEDYTAKSSPHVKVAQQLCGLTGDVSFGKRGAQIDYLITVNGPEPLLYRTSPIDYQYYID
HHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCEEEEEC
KQIGPIAEPVFSIMKLNYMDIASKQLLLI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]