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The map label for this gene is kefC [H]

Identifier: 126173552

GI number: 126173552

Start: 1493126

End: 1494895

Strand: Direct

Name: kefC [H]

Synonym: Sbal_1314

Alternate gene names: 126173552

Gene position: 1493126-1494895 (Clockwise)

Preceding gene: 126173551

Following gene: 126173554

Centisome position: 29.12

GC content: 49.27

Gene sequence:

>1770_bases
ATGGAACAGTCGAGTTTACTCACGTCGGTGCTGCTATTTTTATTGGCGGCGGTTATTTTTGTTCCTTTGGGTAAACGTTT
TGGCGCAGGCCCGATTCTTTCCTACCTAGGTGCTGGCATCATTTTAGGCCCAGGCGGCATGGCCTTAGTTTCTGATCCTG
CTGCTGTGTTGCATTTTGCCGAGTTAGGTGTAGTGCTGATGTTGTTTGTACTTGGACTCGAATTAAATCCAAGTAAATTA
TGGGAACTTCGCAGTGCTATCTTTGGTTTAGGCAGTGGTCAATTGTTGTTGTCATGGGCTGCGATTGGTGGTTTAGCTTG
GGGCTTTGGCTTGTCTGTTGATGCAGCTTTAGTGGTTGGCGCCGCGCTATCTTTATCATCGACAGCCTTTGCCGTGCAGT
TAATGAGTGAGCATAGGTTGCTCACAACCCCACTCGGGCGTGATGCCTTTGGTGTCTTGTTAATGCAAGATCTTGCCGTT
ATCCCCATGTTGCTGCTGACGGCATATTTGGCGCCCAATTCGGCGCAGATTGAACATCATGCCGTGCCTTGGTACTGGAC
GTGTCTAGCCCTAGTAGGGTTTGTGTTAGTGGGCAAATACTTACTGCCAACACTCCTTAAGTTAGTCGCAAGTAGCGGGG
TGCGTGAAGTACTCACCGCCTTTGCGTTACTGCTCGTGATGGGCAGCGCTGAGTTAATGGAGTGGCTTGGACTTTCCGCG
GGTATGGGGGCATTTTTGGCGGGTATTATGCTCGCAAACTCAAGTTATCGACATCAACTCGAAACCGACATCGAACCCTT
TAAAGGCTTATTGCTTGGGCTGTTTTTCATGGCGGTCGGTATGAGTATGGATTTGAAATTATTGATATCAGATCCGTTAC
TTATCTTAGGTATTTTAATGGCGATGCTGCTGATTAAAACGTTTGTGCTGATGGTGCTGGGCCGCATTCGGCACCACAAA
TGGCGACCGAGTATTGCATTGGGGTTGATCCTTGCCGAAGGCGGTGAATTTGCCTTTGTGCTGTTATCCCAGGCGCAGTT
ATCTGGCATTGTCGGCGATAAAATTGCGCAAGTGCTAGTGCTGGCGATTGGTTTATCTATGGCGGTGACGCCGATATTGT
TTACCCTGTTTCGCGCAACTAAGGCCAAGGTGGTGGACACTCGCCTGCCAGATACGATTAATGTCACGGAATCGGAAGTG
GTGATTGCCGGTTTTGGCCGAGTAGGCCAGATAACCGGGCGTATTTTGGCCTCATCAGGGATCCCTTTTGTCGCCTTGGA
TAAGGATGCGAGTCATGTGGATGTGATTCGCAAATATGGCGGTGAGGTCTATTTTGGTGATGCCAGACGCTTAGACATGT
TGATGTCGGCGGGGATCGCGCGCTCGCGTTTGTTATTGCTGGCCGTGGACAGTGTTGAGGATTCCATCGAAATCGCCCAG
CAAGTGAAAACCCATTTCCCTCATATCCACATAGTCGCGCGGGCAAGGGATCGTAACCATGCTTATCGTTTGATGAGCCT
TGGGGTGACAGATGTGTTTCGTGAGACCTTTGGTTCAGCGCTTTCGGCCAGCGAGAAGATCCTCCAAGGTTTAGGTCTAT
CTCAGGTACAAGCCAACGAGCGGGTAAAAATCTTTGCTGAGCATGATAAGAAACTGGTGATTGCGAGCGCAGCACATCAA
AATGATTTAGCGACGTTAATCAATCTATCGAATAAGGGGAAGGCAGAGTTGGAATCCCTTATGCGCGGCGATAGGGAGAA
TGTCAGTTAA

Upstream 100 bases:

>100_bases
TTGTTAATAAATAAATGGGATATCATAGTTGCTAATTCGCCTAGCTGCGGCTGGGCTATTATATGGAACACTGCGCATTC
CTTTTTCCGTTGGAGCCTTC

Downstream 100 bases:

>100_bases
TACGCTGGGTATCATTTGCCATTATCGATTAAGGATTTAGATGTCAAAAGAGAGCATAAATGCTCTCTTTTTTGTTGGAA
ACATATCGACTTTCGCGCTG

Product: potassium efflux system protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MEQSSLLTSVLLFLLAAVIFVPLGKRFGAGPILSYLGAGIILGPGGMALVSDPAAVLHFAELGVVLMLFVLGLELNPSKL
WELRSAIFGLGSGQLLLSWAAIGGLAWGFGLSVDAALVVGAALSLSSTAFAVQLMSEHRLLTTPLGRDAFGVLLMQDLAV
IPMLLLTAYLAPNSAQIEHHAVPWYWTCLALVGFVLVGKYLLPTLLKLVASSGVREVLTAFALLLVMGSAELMEWLGLSA
GMGAFLAGIMLANSSYRHQLETDIEPFKGLLLGLFFMAVGMSMDLKLLISDPLLILGILMAMLLIKTFVLMVLGRIRHHK
WRPSIALGLILAEGGEFAFVLLSQAQLSGIVGDKIAQVLVLAIGLSMAVTPILFTLFRATKAKVVDTRLPDTINVTESEV
VIAGFGRVGQITGRILASSGIPFVALDKDASHVDVIRKYGGEVYFGDARRLDMLMSAGIARSRLLLLAVDSVEDSIEIAQ
QVKTHFPHIHIVARARDRNHAYRLMSLGVTDVFRETFGSALSASEKILQGLGLSQVQANERVKIFAEHDKKLVIASAAHQ
NDLATLINLSNKGKAELESLMRGDRENVS

Sequences:

>Translated_589_residues
MEQSSLLTSVLLFLLAAVIFVPLGKRFGAGPILSYLGAGIILGPGGMALVSDPAAVLHFAELGVVLMLFVLGLELNPSKL
WELRSAIFGLGSGQLLLSWAAIGGLAWGFGLSVDAALVVGAALSLSSTAFAVQLMSEHRLLTTPLGRDAFGVLLMQDLAV
IPMLLLTAYLAPNSAQIEHHAVPWYWTCLALVGFVLVGKYLLPTLLKLVASSGVREVLTAFALLLVMGSAELMEWLGLSA
GMGAFLAGIMLANSSYRHQLETDIEPFKGLLLGLFFMAVGMSMDLKLLISDPLLILGILMAMLLIKTFVLMVLGRIRHHK
WRPSIALGLILAEGGEFAFVLLSQAQLSGIVGDKIAQVLVLAIGLSMAVTPILFTLFRATKAKVVDTRLPDTINVTESEV
VIAGFGRVGQITGRILASSGIPFVALDKDASHVDVIRKYGGEVYFGDARRLDMLMSAGIARSRLLLLAVDSVEDSIEIAQ
QVKTHFPHIHIVARARDRNHAYRLMSLGVTDVFRETFGSALSASEKILQGLGLSQVQANERVKIFAEHDKKLVIASAAHQ
NDLATLINLSNKGKAELESLMRGDRENVS
>Mature_589_residues
MEQSSLLTSVLLFLLAAVIFVPLGKRFGAGPILSYLGAGIILGPGGMALVSDPAAVLHFAELGVVLMLFVLGLELNPSKL
WELRSAIFGLGSGQLLLSWAAIGGLAWGFGLSVDAALVVGAALSLSSTAFAVQLMSEHRLLTTPLGRDAFGVLLMQDLAV
IPMLLLTAYLAPNSAQIEHHAVPWYWTCLALVGFVLVGKYLLPTLLKLVASSGVREVLTAFALLLVMGSAELMEWLGLSA
GMGAFLAGIMLANSSYRHQLETDIEPFKGLLLGLFFMAVGMSMDLKLLISDPLLILGILMAMLLIKTFVLMVLGRIRHHK
WRPSIALGLILAEGGEFAFVLLSQAQLSGIVGDKIAQVLVLAIGLSMAVTPILFTLFRATKAKVVDTRLPDTINVTESEV
VIAGFGRVGQITGRILASSGIPFVALDKDASHVDVIRKYGGEVYFGDARRLDMLMSAGIARSRLLLLAVDSVEDSIEIAQ
QVKTHFPHIHIVARARDRNHAYRLMSLGVTDVFRETFGSALSASEKILQGLGLSQVQANERVKIFAEHDKKLVIASAAHQ
NDLATLINLSNKGKAELESLMRGDRENVS

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=396, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1786232, Length=595, Percent_Identity=43.3613445378151, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1789749, Length=593, Percent_Identity=41.8212478920742, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1786685, Length=529, Percent_Identity=28.1663516068053, Blast_Score=162, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 63174; Mature: 63174

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSSLLTSVLLFLLAAVIFVPLGKRFGAGPILSYLGAGIILGPGGMALVSDPAAVLHFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEECCCCCEEECCHHHHHHHH
ELGVVLMLFVLGLELNPSKLWELRSAIFGLGSGQLLLSWAAIGGLAWGFGLSVDAALVVG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
AALSLSSTAFAVQLMSEHRLLTTPLGRDAFGVLLMQDLAVIPMLLLTAYLAPNSAQIEHH
HHHHHCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AVPWYWTCLALVGFVLVGKYLLPTLLKLVASSGVREVLTAFALLLVMGSAELMEWLGLSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC
GMGAFLAGIMLANSSYRHQLETDIEPFKGLLLGLFFMAVGMSMDLKLLISDPLLILGILM
CHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
AMLLIKTFVLMVLGRIRHHKWRPSIALGLILAEGGEFAFVLLSQAQLSGIVGDKIAQVLV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
LAIGLSMAVTPILFTLFRATKAKVVDTRLPDTINVTESEVVIAGFGRVGQITGRILASSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCC
IPFVALDKDASHVDVIRKYGGEVYFGDARRLDMLMSAGIARSRLLLLAVDSVEDSIEIAQ
CCEEEECCCCHHHHHHHHHCCEEEECCHHHHHHHHHCCHHHHEEEEEEECCHHHHHHHHH
QVKTHFPHIHIVARARDRNHAYRLMSLGVTDVFRETFGSALSASEKILQGLGLSQVQANE
HHHHHCCEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
RVKIFAEHDKKLVIASAAHQNDLATLINLSNKGKAELESLMRGDRENVS
CEEEEEECCCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEQSSLLTSVLLFLLAAVIFVPLGKRFGAGPILSYLGAGIILGPGGMALVSDPAAVLHFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEECCCCCEEECCHHHHHHHH
ELGVVLMLFVLGLELNPSKLWELRSAIFGLGSGQLLLSWAAIGGLAWGFGLSVDAALVVG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
AALSLSSTAFAVQLMSEHRLLTTPLGRDAFGVLLMQDLAVIPMLLLTAYLAPNSAQIEHH
HHHHHCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AVPWYWTCLALVGFVLVGKYLLPTLLKLVASSGVREVLTAFALLLVMGSAELMEWLGLSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC
GMGAFLAGIMLANSSYRHQLETDIEPFKGLLLGLFFMAVGMSMDLKLLISDPLLILGILM
CHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
AMLLIKTFVLMVLGRIRHHKWRPSIALGLILAEGGEFAFVLLSQAQLSGIVGDKIAQVLV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
LAIGLSMAVTPILFTLFRATKAKVVDTRLPDTINVTESEVVIAGFGRVGQITGRILASSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCC
IPFVALDKDASHVDVIRKYGGEVYFGDARRLDMLMSAGIARSRLLLLAVDSVEDSIEIAQ
CCEEEECCCCHHHHHHHHHCCEEEECCHHHHHHHHHCCHHHHEEEEEEECCHHHHHHHHH
QVKTHFPHIHIVARARDRNHAYRLMSLGVTDVFRETFGSALSASEKILQGLGLSQVQANE
HHHHHCCEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
RVKIFAEHDKKLVIASAAHQNDLATLINLSNKGKAELESLMRGDRENVS
CEEEEEECCCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA