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The map label for this gene is aceB [H]

Identifier: 126173554

GI number: 126173554

Start: 1498349

End: 1499998

Strand: Direct

Name: aceB [H]

Synonym: Sbal_1316

Alternate gene names: 126173554

Gene position: 1498349-1499998 (Clockwise)

Preceding gene: 126173552

Following gene: 126173555

Centisome position: 29.22

GC content: 48.48

Gene sequence:

>1650_bases
ATGACGGAACACACTTTGAGTGAACAGCAATTGAATTCGACACTGGGTAAAGCTACAGCAAACGCCACCCTTAATATTGT
GGGTCGTGACATTCCAGGCCAAGAAGTCATCTTTACCGAAGGGGCTGTCGCCTTACTCGAATCCCTTTGTCGTGAATTTG
CCGACGAAGTACCTGCCTTACTCGCTAAACGTAAAGATAAGCAAGCGCGTATCGATAAAGGATCATTACCCGACTTTCTG
CCTGAAACCCGCGCTATCCGTGATGGTGCATGGCAAATTCGTGGAATTCCCGATGACTTGCTTGACCGCCGCGTGGAAAT
CACAGGTCCCGTTGAACGTAAGATGGTGATTAATGCACTCAACGCCAATGCCAAAGTGTTTATGGCCGATTTCGAAGATT
CTTTAGCACCAAGCTGGGAAAAAGTCGTCGAAGGTCAAATCAATCTACGTGATGCCGTGCGTGGTGATATTGAGTACACA
GCACCGGACACGGGTAAGCACTACAAATTAGGACCAAATCCCGCAGTGCTTATTTGCCGCGTTCGTGGTCTGCACCTTAA
AGAAAAACACGTGCAGTTTAACGGCAAAGCGATTTCAGGCTCACTGTTTGATTTCGCACTGTATTTCTACCACAACTATC
GCCAACTTTTGGCCAAGGGCAGTGGTCCATACTTTTATATTCCTAAGTTAGAAAGTCATGTTGAAGCGCGCTGGTGGGCA
AAAGTATTTGCTTTTGTTGAGGAAAGGTTTTGTCTGCAAGCGGGCACGATTAAATGTACTTGCCTGATCGAGACGTTACC
GGCCGTGTTCGAAATGGACGAAATCCTCTATGAGCTGCGTTCCAATATCGTCGCGCTGAACTGTGGTCGCTGGGATTACA
TCTTCAGCTATATCAAAACATTAAAGCGTCATAGCGACCGAGTCTTACCGGATCGCCAAGCCGTCACTATGGATACGCCT
TTCTTAAGCGCTTATTCAAGACTCTTGATTAAGACCTGCCACAAACGCGGTGCGTTAGCGATGGGCGGCATGGCGGCCTT
TATTCCAGCCAAAGATCCGGTTCAGAACGAAGCGGTATTGCAACGAGTTCGTCGAGATAAAGAACTGGAGGCGCGTAACG
GCCACGATGGCACTTGGGTGGCACACCCTGGTCTTGCCGATACCGCTATGGGTATTTTCAACGAATACATAGGCCAAGAT
CACTGTAATCAATTGCATATTACCCGTGATGTCGATGCGCCAATCCTGGCTAGCGAACTGCTTAAAACCTGCGATGGTGA
GCGCACCGAACAGGGGATGCGTCTGAACATTCGTATCGCACTGCAGTATTTAGAGGCGTGGATCAGCGGCAACGGTTGCG
TACCTATTTACGGCTTAATGGAAGATGCAGCTACGGCTGAGATTTCTAGAGCTTCAATTTGGCAATGGATCCAACACGGT
AAGTCGCTGTCAAACGGCAAACTCGTGACCAAGCAACTTTTTAAAGACATGTTGGTTGAAGAGCTGTCGAACGTGAAAAA
AGAAGTGGGTAGCGACAGATTCACCCATGGCAAATTCACCCAAGCGGCGGTATTGCTCGAAGACATTACCACCTCCGACG
AGCTGGTCGATTTCTTAACCTTACCCGGTTACGAAATGCTGACTGCCTAG

Upstream 100 bases:

>100_bases
GTTTTTTGGTGAGTTTATAAGCAGCGGTGATTGGGGATGCTACTGCTTTATATGTCAGCGTTAAGCCTGTGATAGTGGAG
CCTCTTGGGAGGGCATCAAG

Downstream 100 bases:

>100_bases
GATGAACCCATTTGCTTGAACCGTTTTATATCAATCAGATTTAGCTGTGGCGGGGCTACCGCCAACCAAACAATTTAGCA
GAGTGAAACTGGGGGGCAGT

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTEHTLSEQQLNSTLGKATANATLNIVGRDIPGQEVIFTEGAVALLESLCREFADEVPALLAKRKDKQARIDKGSLPDFL
PETRAIRDGAWQIRGIPDDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWEKVVEGQINLRDAVRGDIEYT
APDTGKHYKLGPNPAVLICRVRGLHLKEKHVQFNGKAISGSLFDFALYFYHNYRQLLAKGSGPYFYIPKLESHVEARWWA
KVFAFVEERFCLQAGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTP
FLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPVQNEAVLQRVRRDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQD
HCNQLHITRDVDAPILASELLKTCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
KSLSNGKLVTKQLFKDMLVEELSNVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA

Sequences:

>Translated_549_residues
MTEHTLSEQQLNSTLGKATANATLNIVGRDIPGQEVIFTEGAVALLESLCREFADEVPALLAKRKDKQARIDKGSLPDFL
PETRAIRDGAWQIRGIPDDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWEKVVEGQINLRDAVRGDIEYT
APDTGKHYKLGPNPAVLICRVRGLHLKEKHVQFNGKAISGSLFDFALYFYHNYRQLLAKGSGPYFYIPKLESHVEARWWA
KVFAFVEERFCLQAGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTP
FLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPVQNEAVLQRVRRDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQD
HCNQLHITRDVDAPILASELLKTCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
KSLSNGKLVTKQLFKDMLVEELSNVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA
>Mature_548_residues
TEHTLSEQQLNSTLGKATANATLNIVGRDIPGQEVIFTEGAVALLESLCREFADEVPALLAKRKDKQARIDKGSLPDFLP
ETRAIRDGAWQIRGIPDDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWEKVVEGQINLRDAVRGDIEYTA
PDTGKHYKLGPNPAVLICRVRGLHLKEKHVQFNGKAISGSLFDFALYFYHNYRQLLAKGSGPYFYIPKLESHVEARWWAK
VFAFVEERFCLQAGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTPF
LSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPVQNEAVLQRVRRDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDH
CNQLHITRDVDAPILASELLKTCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHGK
SLSNGKLVTKQLFKDMLVEELSNVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=514, Percent_Identity=69.8443579766537, Blast_Score=751, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=529, Percent_Identity=49.1493383742911, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71982926, Length=421, Percent_Identity=51.0688836104513, Blast_Score=410, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322222, Length=518, Percent_Identity=45.945945945946, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6324212, Length=523, Percent_Identity=45.697896749522, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 61676; Mature: 61545

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHTLSEQQLNSTLGKATANATLNIVGRDIPGQEVIFTEGAVALLESLCREFADEVPAL
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LAKRKDKQARIDKGSLPDFLPETRAIRDGAWQIRGIPDDLLDRRVEITGPVERKMVINAL
HHHCCCHHHCCCCCCCCCCCCCHHHHCCCCEEECCCCHHHHCCEEEECCCHHHHHHHHEE
NANAKVFMADFEDSLAPSWEKVVEGQINLRDAVRGDIEYTAPDTGKHYKLGPNPAVLICR
CCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHCCCEEECCCCCCCCEEECCCCEEEEEE
VRGLHLKEKHVQFNGKAISGSLFDFALYFYHNYRQLLAKGSGPYFYIPKLESHVEARWWA
ECCCCEEHHHEEECCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
KVFAFVEERFCLQAGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKT
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
LKRHSDRVLPDRQAVTMDTPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPVQNEAVL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCCHHHHH
QRVRRDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDHCNQLHITRDVDAPILASEL
HHHHCCCCHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
LKTCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
HHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
KSLSNGKLVTKQLFKDMLVEELSNVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LPGYEMLTA
CCCHHHHCC
>Mature Secondary Structure 
TEHTLSEQQLNSTLGKATANATLNIVGRDIPGQEVIFTEGAVALLESLCREFADEVPAL
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LAKRKDKQARIDKGSLPDFLPETRAIRDGAWQIRGIPDDLLDRRVEITGPVERKMVINAL
HHHCCCHHHCCCCCCCCCCCCCHHHHCCCCEEECCCCHHHHCCEEEECCCHHHHHHHHEE
NANAKVFMADFEDSLAPSWEKVVEGQINLRDAVRGDIEYTAPDTGKHYKLGPNPAVLICR
CCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHCCCEEECCCCCCCCEEECCCCEEEEEE
VRGLHLKEKHVQFNGKAISGSLFDFALYFYHNYRQLLAKGSGPYFYIPKLESHVEARWWA
ECCCCEEHHHEEECCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
KVFAFVEERFCLQAGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKT
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
LKRHSDRVLPDRQAVTMDTPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPVQNEAVL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCCHHHHH
QRVRRDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDHCNQLHITRDVDAPILASEL
HHHHCCCCHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
LKTCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
HHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
KSLSNGKLVTKQLFKDMLVEELSNVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LPGYEMLTA
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]