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The map label for this gene is cysM [H]

Identifier: 126173242

GI number: 126173242

Start: 1144824

End: 1145702

Strand: Direct

Name: cysM [H]

Synonym: Sbal_0998

Alternate gene names: 126173242

Gene position: 1144824-1145702 (Clockwise)

Preceding gene: 126173236

Following gene: 126173244

Centisome position: 22.33

GC content: 51.54

Gene sequence:

>879_bases
GTGTCTGACTTTCCGACAATTGAAGCCTGTATTGGGCAAACTCCGCTGGTTCGCTTGCAGCGGCTTAACTGTGGCACCTC
AACTGTACTGTTAAAGTTGGAAGGGAATAACCCAGCGGGTTCAGTGAAGGATCGTGCAGCACTCAATATGATCATTCAGG
CCGAACTGCGTCAAGAGATCCGCCCGGGTGATACGCTCATCGAGGCGACAAGTGGCAATACTGGGATTGCGCTAGCGATG
GCGGCGGCGATCAAAGGCTACAAGATGATCCTGATTATGCCCGAGAACTCGACCCAAGAGCGTAAGGATGCGATGCAAGC
TTATGGCGCAGCACTCATGCTGGTGGATAACATGGAAACGGCGCGGGATTTGGCACTGCAATTACAAACCGAAGGTAAAG
GCAAGGTGCTGGATCAGTTTAATAATCAAGATAATGCGAATGCGCATTTCCTCACCACAGGTCCGGAAATCTGGCAACAG
AGTCAAGGTAAAATCACTCACTTTGTCTCTAGCATGGGGACGACAGGCACCATAATGGGCGTGTCTAAATACCTTAAAAG
CTGTAATCCTGACATTACGATTGTTGGCCTTCAGCCCGCCGATGGCAGTAGCATTCCGGGGATCCGCCGCTGGCCGCAGG
CGTACTTGCCGGGGATTTTCGATGCATCCCGTGTAGATTTAGTCATGGATGTTGAAGAGCAAGACGCAAAAACCATGGCA
AGAGCCTTAGCGCGCGAAGAAGGGATTTGTGCTGGCGTCAGCTCGGGTGGTGCAGTGTTTGCTGCGCTTGAGATAGCCAG
ACTGAATCCAGATTCAGTGGTCGTGGCGATTGTTTGTGATAGGGGCGATCGTTACCTTTCATCAGGGCTTTTTTCCTGA

Upstream 100 bases:

>100_bases
TTTATTGTATGCCATAGATCATTTTCACTGTGTTTGTGCATGCTAACCCACTTAGAATAGGTTAACGCTTAGTTGTTTTA
TCAAGTAAAGGATAATCATA

Downstream 100 bases:

>100_bases
GTCCAAGATATTTCGCCTAAGTTATTTGACGACAAGCATTCTTCATTAGTAAAAATGGGCGGAATTCGCCCATTTTTATT
GACTCTTCATGATCATTTTT

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDFPTIEACIGQTPLVRLQRLNCGTSTVLLKLEGNNPAGSVKDRAALNMIIQAELRQEIRPGDTLIEATSGNTGIALAM
AAAIKGYKMILIMPENSTQERKDAMQAYGAALMLVDNMETARDLALQLQTEGKGKVLDQFNNQDNANAHFLTTGPEIWQQ
SQGKITHFVSSMGTTGTIMGVSKYLKSCNPDITIVGLQPADGSSIPGIRRWPQAYLPGIFDASRVDLVMDVEEQDAKTMA
RALAREEGICAGVSSGGAVFAALEIARLNPDSVVVAIVCDRGDRYLSSGLFS

Sequences:

>Translated_292_residues
MSDFPTIEACIGQTPLVRLQRLNCGTSTVLLKLEGNNPAGSVKDRAALNMIIQAELRQEIRPGDTLIEATSGNTGIALAM
AAAIKGYKMILIMPENSTQERKDAMQAYGAALMLVDNMETARDLALQLQTEGKGKVLDQFNNQDNANAHFLTTGPEIWQQ
SQGKITHFVSSMGTTGTIMGVSKYLKSCNPDITIVGLQPADGSSIPGIRRWPQAYLPGIFDASRVDLVMDVEEQDAKTMA
RALAREEGICAGVSSGGAVFAALEIARLNPDSVVVAIVCDRGDRYLSSGLFS
>Mature_291_residues
SDFPTIEACIGQTPLVRLQRLNCGTSTVLLKLEGNNPAGSVKDRAALNMIIQAELRQEIRPGDTLIEATSGNTGIALAMA
AAIKGYKMILIMPENSTQERKDAMQAYGAALMLVDNMETARDLALQLQTEGKGKVLDQFNNQDNANAHFLTTGPEIWQQS
QGKITHFVSSMGTTGTIMGVSKYLKSCNPDITIVGLQPADGSSIPGIRRWPQAYLPGIFDASRVDLVMDVEEQDAKTMAR
ALAREEGICAGVSSGGAVFAALEIARLNPDSVVVAIVCDRGDRYLSSGLFS

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=314, Percent_Identity=36.3057324840764, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI295821200, Length=314, Percent_Identity=36.3057324840764, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI4557415, Length=314, Percent_Identity=36.3057324840764, Blast_Score=171, Evalue=8e-43,
Organism=Escherichia coli, GI2367138, Length=290, Percent_Identity=66.8965517241379, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788754, Length=305, Percent_Identity=40.327868852459, Blast_Score=181, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17562970, Length=297, Percent_Identity=39.3939393939394, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17535051, Length=299, Percent_Identity=40.8026755852843, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI32566674, Length=291, Percent_Identity=39.8625429553265, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=39.3333333333333, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17561720, Length=297, Percent_Identity=39.3939393939394, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI32566672, Length=213, Percent_Identity=35.2112676056338, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17534315, Length=310, Percent_Identity=36.4516129032258, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25147552, Length=312, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321594, Length=311, Percent_Identity=35.3697749196142, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6321449, Length=324, Percent_Identity=32.7160493827161, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24643623, Length=311, Percent_Identity=37.9421221864952, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI20129101, Length=311, Percent_Identity=37.9421221864952, Blast_Score=147, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 31295; Mature: 31164

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFPTIEACIGQTPLVRLQRLNCGTSTVLLKLEGNNPAGSVKDRAALNMIIQAELRQEI
CCCCCCHHHHHCCCHHHHHEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
RPGDTLIEATSGNTGIALAMAAAIKGYKMILIMPENSTQERKDAMQAYGAALMLVDNMET
CCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEECCHH
ARDLALQLQTEGKGKVLDQFNNQDNANAHFLTTGPEIWQQSQGKITHFVSSMGTTGTIMG
HHHEEEEEECCCCCCHHHHCCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHCCCCCHHHH
VSKYLKSCNPDITIVGLQPADGSSIPGIRRWPQAYLPGIFDASRVDLVMDVEEQDAKTMA
HHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCHHHCCCCCCCCCEEEEEECCHHHHHHHH
RALAREEGICAGVSSGGAVFAALEIARLNPDSVVVAIVCDRGDRYLSSGLFS
HHHHHHCCCEEECCCCCEEEEEEEEEECCCCCEEEEEEECCCCHHHHCCCCC
>Mature Secondary Structure 
SDFPTIEACIGQTPLVRLQRLNCGTSTVLLKLEGNNPAGSVKDRAALNMIIQAELRQEI
CCCCCHHHHHCCCHHHHHEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
RPGDTLIEATSGNTGIALAMAAAIKGYKMILIMPENSTQERKDAMQAYGAALMLVDNMET
CCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEECCHH
ARDLALQLQTEGKGKVLDQFNNQDNANAHFLTTGPEIWQQSQGKITHFVSSMGTTGTIMG
HHHEEEEEECCCCCCHHHHCCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHCCCCCHHHH
VSKYLKSCNPDITIVGLQPADGSSIPGIRRWPQAYLPGIFDASRVDLVMDVEEQDAKTMA
HHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCHHHCCCCCCCCCEEEEEECCHHHHHHHH
RALAREEGICAGVSSGGAVFAALEIARLNPDSVVVAIVCDRGDRYLSSGLFS
HHHHHHCCCEEECCCCCEEEEEEEEEECCCCCEEEEEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]