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The map label for this gene is nah [H]

Identifier: 125624947

GI number: 125624947

Start: 2145583

End: 2146722

Strand: Reverse

Name: nah [H]

Synonym: llmg_2177

Alternate gene names: 125624947

Gene position: 2146722-2145583 (Counterclockwise)

Preceding gene: 125624948

Following gene: 125624946

Centisome position: 84.87

GC content: 36.75

Gene sequence:

>1140_bases
ATGAATGATATTTTACAACTTACAATTGTTTTAATTGCCTCGCTAATTGCAACCCTTGCTTCACGGCGTCTTAAAATTCC
TGCTGTTATTGGACAGATGCTTGTGGGAATTTTGATTGCTCCGTCAGTTTTAGGGCTTGTTCATAGCGGACATGTTTTAG
AAGTGATGTCAGAAATCGGTGTGATTTTACTCATGTTTTTAGCGGGTCTTGAGAGTGATTTAACGGTTTTAAAGAAAAAT
TTCAAAGCATCAATGCTTGTAGCCATTGGCGGTGTGATTGTTCCTTTAATAGTTTTTGGCCTAGTGGCTTTTAGTTTTGG
CTACGGAATGTCTACGAGTTTCTTTTACGGAATTGTTTTTGCCGCAACATCGGTTTCAATTACCGTTGAAGTTTTGCAAG
AATATGGAAAACTCAGTACACGTGCAGGCTCAATTATTCTAGGAGCAGCGGTTGTTGATGATATTTTAGCCGTTTTGATT
TTATCAATTTTTACCAGTTTCAAAAATGGAGGGTCTGGGACTCATCTTTTCTTCCAGTTTTTACTTGAACTTCTCTTTTT
TGCCTTTTTATTTGTTGTCCATAAATTGATTCCCAGATTTTGGAAGTTTGTCCAAAAACTGCCAATCGCCAACAAGAATA
CGATTGTTGCTTTGATCATCTGTTTAGGATTGAGTTTACTTGCAGATAGTGTGGGAATGTCAGCCGTGATAGGGAGCTTC
TTTGCAGGACTTGCTATTTCACAAACAGAAGTCAGTCATAAAATTGAAGAATATACTTCAGCCATTGGGTATGTGATTTT
TATCCCAGTCTTCTTTGTACTCATTGCCATATCCGTTCAATTTGACAGTTTAATTCATCATCCATGGATTATTTTGCTCT
TTACACTTCTAGCGATTTTGACCAAATTTATTCCTGCCTATTTTGTTGGGAAATCTAATAAATTGAGTACCGGGGAAAGT
ATGCTGATTGGGACGGGAATGATTTCACGTGGAGAAATGGCCTTGATTGTGGCACAAATTGGACTGACAAGTGCCATTAT
TACTGATGAAGTTTATTCTGAATTGGTCATTGTCATAATTTTAGCAACTGTCCTAGCTCCATTTTTAATCAAGTTAGTCT
TGAAAAAATATGATAATTAA

Upstream 100 bases:

>100_bases
AAACTGGCAACAGCTATCCTGTGTTTCGTTCGGTCATAAGAGATAAAAACGAATAAGACAAAAGCTCGTTTCGTCTTATC
GGTTATGATATAATCAACTT

Downstream 100 bases:

>100_bases
GGAAAAAATAATTTTTAAAATTTCATCTTATTCCCCAAAAAAGACTGAAAAAGTGGTAAAATAGAAAAAATGCTTTTAGA
GAATGGCGCCATCTGCTATG

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGLESDLTVLKKN
FKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGTHLFFQFLLELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTLLAILTKFIPAYFVGKSNKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKLVLKKYDN

Sequences:

>Translated_379_residues
MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGLESDLTVLKKN
FKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGTHLFFQFLLELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTLLAILTKFIPAYFVGKSNKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKLVLKKYDN
>Mature_379_residues
MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGLESDLTVLKKN
FKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGTHLFFQFLLELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTLLAILTKFIPAYFVGKSNKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKLVLKKYDN

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=389, Percent_Identity=25.1928020565553, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786232, Length=363, Percent_Identity=23.9669421487603, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789749, Length=367, Percent_Identity=22.0708446866485, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322367, Length=385, Percent_Identity=25.1948051948052, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 40910; Mature: 40910

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]