Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 125624708

GI number: 125624708

Start: 1906217

End: 1907509

Strand: Reverse

Name: aroA [H]

Synonym: llmg_1926

Alternate gene names: 125624708

Gene position: 1907509-1906217 (Counterclockwise)

Preceding gene: 125624709

Following gene: 125624707

Centisome position: 75.41

GC content: 39.44

Gene sequence:

>1293_bases
ATGAAATTAAAAATAAATTCACAAGGGTTAAAAGGGCGTTTAAAGGTTCCAGGAGATAAATCAATTTCACATCGAAGCAT
TATGTTTGGCTCAATTGCTAAAGGAAAAACAATCATTCATGATATTTTGCGTGGCGAAGATGTTTTATCTACCATTGAAG
CCTTTCGAGCTTTAGGAGTTGAGATTGAGGACGATGGTCAAGTTATTACTGTCCATGGTCAGGGGATTTCAAAACTTAAG
GAGCCAGAAAAAGCACTTGATATGGGAAATTCTGGAACTTCAACCCGCCTGTTGTCGGGGATTTTAGCAGGACTTCCTTT
TGAAGCAACTTTGTTTGGGGATGATAGTTTATCCAAAAGACCAATGGACCGTGTCGCAACTCCGCTTCAAATGATGGGGG
CTGAAATAGTTGGACAAACTGATAAGGTTAAATTACCGATGACAATCAAAGGAAGTGCTCATTTAAAAGCAATCGATTAT
ATCCTTCCGGTCGCTTCGGCCCAAGTAAAATCGGCGGTAATTTTTGCTGCTTTACAAGCAGAAGGACTGACAAAAGTTGT
TGAGAAGGAAAAAACACGCTCACATACAGAAGAAATGTTAGTTCAATTTGGCGGAGAAATTACTGTTTCTGATAAAACCA
TTCTTGTTCCTGGCGGGCAAAAACTTTTGGGGCAAGAGGTGACAGTTCCTGGTGACATTAGTTCAGCAGCCTTTTGGCTT
GTAGCTGGCTTAGTTGTTGAAAATTCAGGACTTATCTTGGAAAATGTTGGAATTAATGAAACAAGAACGGGTATTTTAGA
AGTCATTCAGGCAATGGGTGGCCAGTTGGAAATTTTAGAGCAAGATGAGGTGGCAAAAGCCGCGACTCTAAAAGTAAAAG
CGAGTCAACTTAAGGGAACTGAAATATCGGGTGATTTAATTCCAAGATTAATTGATGAATTACCAATTATTGCGCTTTTG
GCTACACAAGCCGAAGGTAAAACAATTATTCGCGATGCGGCTGAACTTAAAGTTAAGGAAACCGACCGGATTGCTGTTGT
GGCTGATGCACTCAATAGTATGGGTGCAAATATTGAACCAACAGATGATGGAATGATTATTCAAGGTGGAACAAAATTAC
ATGCTCCAGAAAATGCAATTAATACTTTAGGTGATCACAGAATTGGGATGATGGTTGCAATTGCTGCACTTTTGGTTGAA
AATGGTGAAATTGAGCTTGAACGAGCTGAGGCCATTCAAACGAGCTATCCAAGTTTCTTTGATGATTTAGAAAAATTGTC
AGGAAATCTTTGA

Upstream 100 bases:

>100_bases
ATTCTTAGTCTTAAAATCTTAGGAAGAAATGATAAAAATAAGAGGGCCTTGAGCGCCCTTTTATGCTATAATAAATACTA
AAAAATGTTTAGGAAATAAA

Downstream 100 bases:

>100_bases
AATTAAATGATAGGAAGTAAAAAATGAGTATCATTTTAATTGGATTTATGGGTGCCGGAAAATCAACGGTGGCAAAACTT
TTAGCAGAAGAATTTACTGA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTIIHDILRGEDVLSTIEAFRALGVEIEDDGQVITVHGQGISKLK
EPEKALDMGNSGTSTRLLSGILAGLPFEATLFGDDSLSKRPMDRVATPLQMMGAEIVGQTDKVKLPMTIKGSAHLKAIDY
ILPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGEITVSDKTILVPGGQKLLGQEVTVPGDISSAAFWL
VAGLVVENSGLILENVGINETRTGILEVIQAMGGQLEILEQDEVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAEGKTIIRDAAELKVKETDRIAVVADALNSMGANIEPTDDGMIIQGGTKLHAPENAINTLGDHRIGMMVAIAALLVE
NGEIELERAEAIQTSYPSFFDDLEKLSGNL

Sequences:

>Translated_430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTIIHDILRGEDVLSTIEAFRALGVEIEDDGQVITVHGQGISKLK
EPEKALDMGNSGTSTRLLSGILAGLPFEATLFGDDSLSKRPMDRVATPLQMMGAEIVGQTDKVKLPMTIKGSAHLKAIDY
ILPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGEITVSDKTILVPGGQKLLGQEVTVPGDISSAAFWL
VAGLVVENSGLILENVGINETRTGILEVIQAMGGQLEILEQDEVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAEGKTIIRDAAELKVKETDRIAVVADALNSMGANIEPTDDGMIIQGGTKLHAPENAINTLGDHRIGMMVAIAALLVE
NGEIELERAEAIQTSYPSFFDDLEKLSGNL
>Mature_430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTIIHDILRGEDVLSTIEAFRALGVEIEDDGQVITVHGQGISKLK
EPEKALDMGNSGTSTRLLSGILAGLPFEATLFGDDSLSKRPMDRVATPLQMMGAEIVGQTDKVKLPMTIKGSAHLKAIDY
ILPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGEITVSDKTILVPGGQKLLGQEVTVPGDISSAAFWL
VAGLVVENSGLILENVGINETRTGILEVIQAMGGQLEILEQDEVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAEGKTIIRDAAELKVKETDRIAVVADALNSMGANIEPTDDGMIIQGGTKLHAPENAINTLGDHRIGMMVAIAALLVE
NGEIELERAEAIQTSYPSFFDDLEKLSGNL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=428, Percent_Identity=25.9345794392523, Blast_Score=108, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320332, Length=460, Percent_Identity=23.0434782608696, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45805; Mature: 45805

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTIIHDILRGEDVLSTIEAFRALGV
CEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCC
EIEDDGQVITVHGQGISKLKEPEKALDMGNSGTSTRLLSGILAGLPFEATLFGDDSLSKR
EECCCCCEEEEECCCCHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PMDRVATPLQMMGAEIVGQTDKVKLPMTIKGSAHLKAIDYILPVASAQVKSAVIFAALQA
CHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLTKVVEKEKTRSHTEEMLVQFGGEITVSDKTILVPGGQKLLGQEVTVPGDISSAAFWL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEECCCHHHCCCCCCCCCCCHHHHHHH
VAGLVVENSGLILENVGINETRTGILEVIQAMGGQLEILEQDEVAKAATLKVKASQLKGT
HHHHHEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHEEEEEHHHCCCC
EISGDLIPRLIDELPIIALLATQAEGKTIIRDAAELKVKETDRIAVVADALNSMGANIEP
CCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCEEECCCCEEHHHHHHHHCCCCCCC
TDDGMIIQGGTKLHAPENAINTLGDHRIGMMVAIAALLVENGEIELERAEAIQTSYPSFF
CCCCEEEECCCEECCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHH
DDLEKLSGNL
HHHHHHCCCC
>Mature Secondary Structure
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTIIHDILRGEDVLSTIEAFRALGV
CEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCC
EIEDDGQVITVHGQGISKLKEPEKALDMGNSGTSTRLLSGILAGLPFEATLFGDDSLSKR
EECCCCCEEEEECCCCHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PMDRVATPLQMMGAEIVGQTDKVKLPMTIKGSAHLKAIDYILPVASAQVKSAVIFAALQA
CHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLTKVVEKEKTRSHTEEMLVQFGGEITVSDKTILVPGGQKLLGQEVTVPGDISSAAFWL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEECCCHHHCCCCCCCCCCCHHHHHHH
VAGLVVENSGLILENVGINETRTGILEVIQAMGGQLEILEQDEVAKAATLKVKASQLKGT
HHHHHEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHEEEEEHHHCCCC
EISGDLIPRLIDELPIIALLATQAEGKTIIRDAAELKVKETDRIAVVADALNSMGANIEP
CCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCEEECCCCEEHHHHHHHHCCCCCCC
TDDGMIIQGGTKLHAPENAINTLGDHRIGMMVAIAALLVENGEIELERAEAIQTSYPSFF
CCCCEEEECCCEECCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHH
DDLEKLSGNL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]