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The map label for this gene is aroK

Identifier: 125624707

GI number: 125624707

Start: 1905705

End: 1906193

Strand: Reverse

Name: aroK

Synonym: llmg_1925

Alternate gene names: 125624707

Gene position: 1906193-1905705 (Counterclockwise)

Preceding gene: 125624708

Following gene: 125624706

Centisome position: 75.36

GC content: 34.36

Gene sequence:

>489_bases
ATGAGTATCATTTTAATTGGATTTATGGGTGCCGGAAAATCAACGGTGGCAAAACTTTTAGCAGAAGAATTTACTGATTT
AGATAAGTTGATTGAAGAAGAGATTGAAATGCCAATTGCGACTTTTTTTGAATTATTTGGAGAAGCTGATTTTCGTAAAA
TTGAAAATGAGGTTTTTGAGCTTGCTGTTCAAAAAGATATTATTATCGCAACTGGTGGAGGAATCATAGAAAATCCAAAG
AATTTAAATGTTCTTGATAGAGCATCACGAGTTGTATTTTTGACTGCTGATTTTGATACTTTATGGAAGCGAATTTCCAT
GGATTGGCAGAATGTTCGACCTTTAGCTCAAGACAAAGAAGCTGCTCAACTTTTATTTGAAAAAAGAATGAAAGACTATT
CATTGGTTGCGGATTTAACAATTGATGTGACCGATAAAAGTCCAGAGCAGATTGCAGAGCAGATTAGAGAAAAGTGGGAG
ATAGAGTAG

Upstream 100 bases:

>100_bases
TTGAACGAGCTGAGGCCATTCAAACGAGCTATCCAAGTTTCTTTGATGATTTAGAAAAATTGTCAGGAAATCTTTGAAAT
TAAATGATAGGAAGTAAAAA

Downstream 100 bases:

>100_bases
GATGAAAATTGCATATTTAGGTCCACGAGGTTCTTTTTGCTCAGTCGTAGCCGAAGCAGCTTTTAAATCTGAGGAGTTGT
ACTCTTATGCAACTATTTTG

Product: AroK protein

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFELAVQKDIIIATGGGIIENPK
NLNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKEAAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWE
IE

Sequences:

>Translated_162_residues
MSIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFELAVQKDIIIATGGGIIENPK
NLNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKEAAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWE
IE
>Mature_161_residues
SIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFELAVQKDIIIATGGGIIENPKN
LNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKEAAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWEI
E

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=163, Percent_Identity=34.9693251533742, Blast_Score=80, Evalue=5e-17,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=32.7160493827161, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_LACLM (P43906)

Other databases:

- EMBL:   X78413
- EMBL:   AM406671
- PIR:   S52581
- RefSeq:   YP_001033190.1
- ProteinModelPortal:   P43906
- SMR:   P43906
- STRING:   P43906
- GeneID:   4798412
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_1925
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   WLDCDIE
- ProtClustDB:   CLSK697918
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18529; Mature: 18397

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 28-28 BINDING 52-52 BINDING 73-73 BINDING 113-113 BINDING 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFE
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
LAVQKDIIIATGGGIIENPKNLNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKE
HHHHCCEEEEECCCEECCCCCCCHHHHCCEEEEEEECHHHHHHHHCCCHHHCCCCCCCHH
AAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWEIE
HHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
LAVQKDIIIATGGGIIENPKNLNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKE
HHHHCCEEEEECCCEECCCCCCCHHHHCCEEEEEEECHHHHHHHHCCCHHHCCCCCCCHH
AAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWEIE
HHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7823907