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The map label for this gene is tyrA

Identifier: 125624709

GI number: 125624709

Start: 1907629

End: 1908693

Strand: Reverse

Name: tyrA

Synonym: llmg_1927

Alternate gene names: 125624709

Gene position: 1908693-1907629 (Counterclockwise)

Preceding gene: 125624710

Following gene: 125624708

Centisome position: 75.46

GC content: 35.21

Gene sequence:

>1065_bases
ATGAAAAAGATATTAATTATAGGTCTCGGACTGATTGGAAGTTCTATAGCCCTAGGCATAAAAAAAGCCCATCCTGAGTT
TGAAATTCTTGGTTCGGACCGTGAAGAAGTTGAAAATATTGCTCAAAAACGTGGAATTATTGATTCTAAGGTCGAATTAG
TTAAAGGAGCCCAAGAAGCAGATATTATTATTTTAGCTGTGCCAATTTCAGTGACTCTCGAGCTTTTAAAGCAAATTGCA
ACGTTTGATTTAAAAGATGGACTTTTGATTACTGATGCTGGTTCAACCAAGAGTGAGATTGTCGAGCTAGCTAATCAACT
TTTTTCTGGGACAAAAGTAAAATTTATCGGAGGGCATCCGATGGCTGGCTCTCATAAATCTGGCGTAATGGCGGCAGATC
TTAATTTATTTGAAAATGCTTATTATGTTTTGACAGAAGAAAGTCAAGAATTAAGAGAGTTACTTAAGGGACTTCATGCT
AAATTTATTATTTTAGATGCCAAGGAACATGATAAAGTAACGGGTCAAGTGTCTCATTTTCCACATATTTTGGCTTCAAC
TCTGGTCTGGCAATCAGACGATTATGCTAAAGAGCATCCTTTAGTCAAACATTTAGCTGCTGGAGGTTTTCGTGATTTAA
CGAGAATCGCTGAGGCTGACAGCTTAATGTGGACTAGTGTCTTACTTTCTAATCCGGAAATTACATTAGAGAGAATTGAG
AATTTTAAAAAACACTTAGATGAAATTGCTTTAAAAATTACAAAAAGAGATTCCCAAGCTATTGAACACTTTTTTGAAGA
AGGTAAAAAGATTCGACAAGCAATGGAAATTCATAAAGGGGCACTGCCAAACTTTTATGATTTGTTTATCTCGGTTCCCG
ATGAAAAAGGAGTTGTTTTACGAGTTTTAGCACTCTTACAGGATTTTTCGATTACAAATATCAAAATTAATGAAGAAAAT
CGTGAAGATATTCATGGTCAACTGCAAATCTCTTTTAAACGAGCAGAAGATTTGCAAGAGGCGCGTGAAATTATTGAAAA
AGCAACTGATTTTACAGTTGTTTGA

Upstream 100 bases:

>100_bases
CTATCTAGCAAAACTTATTTTGGATAAACTAGAATTTCAAATTGCAATAAGTTCTGAAATTGGTGAGGGAACTTGTGTGA
TGATCAAGAAAGAGTAAAGA

Downstream 100 bases:

>100_bases
TAAAGGTTAAAGAACTGACATTCTTAGTCTTAAAATCTTAGGAAGAAATGATAAAAATAAGAGGGCCTTGAGCGCCCTTT
TATGCTATAATAAATACTAA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKKILIIGLGLIGSSIALGIKKAHPEFEILGSDREEVENIAQKRGIIDSKVELVKGAQEADIIILAVPISVTLELLKQIA
TFDLKDGLLITDAGSTKSEIVELANQLFSGTKVKFIGGHPMAGSHKSGVMAADLNLFENAYYVLTEESQELRELLKGLHA
KFIILDAKEHDKVTGQVSHFPHILASTLVWQSDDYAKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITLERIE
NFKKHLDEIALKITKRDSQAIEHFFEEGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLRVLALLQDFSITNIKINEEN
REDIHGQLQISFKRAEDLQEAREIIEKATDFTVV

Sequences:

>Translated_354_residues
MKKILIIGLGLIGSSIALGIKKAHPEFEILGSDREEVENIAQKRGIIDSKVELVKGAQEADIIILAVPISVTLELLKQIA
TFDLKDGLLITDAGSTKSEIVELANQLFSGTKVKFIGGHPMAGSHKSGVMAADLNLFENAYYVLTEESQELRELLKGLHA
KFIILDAKEHDKVTGQVSHFPHILASTLVWQSDDYAKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITLERIE
NFKKHLDEIALKITKRDSQAIEHFFEEGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLRVLALLQDFSITNIKINEEN
REDIHGQLQISFKRAEDLQEAREIIEKATDFTVV
>Mature_354_residues
MKKILIIGLGLIGSSIALGIKKAHPEFEILGSDREEVENIAQKRGIIDSKVELVKGAQEADIIILAVPISVTLELLKQIA
TFDLKDGLLITDAGSTKSEIVELANQLFSGTKVKFIGGHPMAGSHKSGVMAADLNLFENAYYVLTEESQELRELLKGLHA
KFIILDAKEHDKVTGQVSHFPHILASTLVWQSDDYAKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITLERIE
NFKKHLDEIALKITKRDSQAIEHFFEEGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLRVLALLQDFSITNIKINEEN
REDIHGQLQISFKRAEDLQEAREIIEKATDFTVV

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TYRA_LACLM (P43901)

Other databases:

- EMBL:   X78413
- EMBL:   AM406671
- PIR:   S52579
- RefSeq:   YP_001033192.1
- ProteinModelPortal:   P43901
- SMR:   P43901
- STRING:   P43901
- GeneID:   4799070
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_1927
- eggNOG:   COG0287
- HOGENOM:   HBG544990
- OMA:   QRAIRWG
- ProtClustDB:   PRK06545
- GO:   GO:0005488
- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21363

Pfam domain/function: PF02153 PDH; SSF48179 6DGDH_C_like

EC number: =1.3.1.12

Molecular weight: Translated: 39531; Mature: 39531

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS51176 PDH_ADH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIIGLGLIGSSIALGIKKAHPEFEILGSDREEVENIAQKRGIIDSKVELVKGAQEA
CCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCC
DIIILAVPISVTLELLKQIATFDLKDGLLITDAGSTKSEIVELANQLFSGTKVKFIGGHP
CEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCC
MAGSHKSGVMAADLNLFENAYYVLTEESQELRELLKGLHAKFIILDAKEHDKVTGQVSHF
CCCCCCCCEEEEHHHHHCCEEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
PHILASTLVWQSDDYAKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITLERIE
HHHHHHHHHCCCCCCHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
NFKKHLDEIALKITKRDSQAIEHFFEEGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
RVLALLQDFSITNIKINEENREDIHGQLQISFKRAEDLQEAREIIEKATDFTVV
HHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKILIIGLGLIGSSIALGIKKAHPEFEILGSDREEVENIAQKRGIIDSKVELVKGAQEA
CCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCC
DIIILAVPISVTLELLKQIATFDLKDGLLITDAGSTKSEIVELANQLFSGTKVKFIGGHP
CEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCC
MAGSHKSGVMAADLNLFENAYYVLTEESQELRELLKGLHAKFIILDAKEHDKVTGQVSHF
CCCCCCCCEEEEHHHHHCCEEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
PHILASTLVWQSDDYAKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITLERIE
HHHHHHHHHCCCCCCHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
NFKKHLDEIALKITKRDSQAIEHFFEEGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
RVLALLQDFSITNIKINEENREDIHGQLQISFKRAEDLQEAREIIEKATDFTVV
HHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7823907