Click here to switch to the map view.

The map label for this gene is cmhR [H]

Identifier: 125623787

GI number: 125623787

Start: 914269

End: 915222

Strand: Direct

Name: cmhR [H]

Synonym: llmg_0947

Alternate gene names: 125623787

Gene position: 914269-915222 (Clockwise)

Preceding gene: 125623786

Following gene: 125623788

Centisome position: 36.14

GC content: 35.64

Gene sequence:

>954_bases
ATGACGATAAGTTTACAACAACTCAAATATTTTATTGAAGTGGCTAAGATTGGCTCAATCAATCAGGCAGCTGAGATTCT
CTATATTACACAGCCTAGTCTGTCAAAGTCAATCAAAGACATTGAAATAGAAGTAGGATTGCCCCTTTTACAACGTTCAA
GCAAAGGAATTTCGCTGACCGCAGAAGGAACCGAGTTTTTAGGTTATGCTAGACAAGTTGTTGAACAATCTGATTTATTG
GAAGCGCGGTGGTTGGACAAAAAGCCATCAAGAAAACTATGTGCCATCTCGACACAGCACTATGCTTTTGCCGTCAATGC
TTTTGTAAATATGGTTAAAAAAACAGAAAGTCAAGGAATTGACGAATACGAATATACTTTACGAGAGGCCCGCACTTATG
AAATTATAGAAGATGTGAAGGCCTTGCGCAGTGAACTTGGCATTCTTTACAAAAATTCTTATAACGCAAATGTGATTGAC
AAAATTTTAAAAGAAAATCGGCTAACCTTTCATTCCTTATTTTTGGCTGAGCCTCATATTTTTGTAAGTTCGACCAATCC
ATTAGCTGACCGACAATTTGTAAGCTTAGAAGATTTAGAAAAATTTCCACGCTTGTCTTATGAGCAAGGCGAGCATAATT
CTTTCTATTTTTCTGAAGAGATTTTATCGACTGTTTACGCTAAAAAAGACATAAAAGTGGGAGATCGAGCCACAATTTTT
AATCTAATGATTGGCTTAAATGGTTATACCATTTCAACAGGTATTGTCAGTCAGGATTTAAATGGTGATAATATTGTCGC
TATTCCTTTAGCAGTTGATGATAATATAGAAATTGGCTGGATTTCACTCAACGATTTTCAACTAACCAGACAAGCTGAAC
TCTATATCAAAGAATTAGAAGAGATTGTTCATCCCTTTGATATTCGTGAGAGTAAAAAAAATAGTGACGACTAA

Upstream 100 bases:

>100_bases
TGGTCAGTAAAAAATAATAACTGAAAGTTCTGTCAGTAAATACAAAGTTACTGACCAGATTTTTGATTTTTGAATTAAAA
ATCTAATGAGGAAAAAAATA

Downstream 100 bases:

>100_bases
TCAAATCTTTTCTGTCAGTAATTTTTTACCGACAGAAAGGAGTCATCAAAGAATCGCTCACTTTGCTAGTAAAAATGATA
CCTGTCGTTACTGACAGGCT

Product: putative HTH-type transcriptional regulator cmhR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTISLQQLKYFIEVAKIGSINQAAEILYITQPSLSKSIKDIEIEVGLPLLQRSSKGISLTAEGTEFLGYARQVVEQSDLL
EARWLDKKPSRKLCAISTQHYAFAVNAFVNMVKKTESQGIDEYEYTLREARTYEIIEDVKALRSELGILYKNSYNANVID
KILKENRLTFHSLFLAEPHIFVSSTNPLADRQFVSLEDLEKFPRLSYEQGEHNSFYFSEEILSTVYAKKDIKVGDRATIF
NLMIGLNGYTISTGIVSQDLNGDNIVAIPLAVDDNIEIGWISLNDFQLTRQAELYIKELEEIVHPFDIRESKKNSDD

Sequences:

>Translated_317_residues
MTISLQQLKYFIEVAKIGSINQAAEILYITQPSLSKSIKDIEIEVGLPLLQRSSKGISLTAEGTEFLGYARQVVEQSDLL
EARWLDKKPSRKLCAISTQHYAFAVNAFVNMVKKTESQGIDEYEYTLREARTYEIIEDVKALRSELGILYKNSYNANVID
KILKENRLTFHSLFLAEPHIFVSSTNPLADRQFVSLEDLEKFPRLSYEQGEHNSFYFSEEILSTVYAKKDIKVGDRATIF
NLMIGLNGYTISTGIVSQDLNGDNIVAIPLAVDDNIEIGWISLNDFQLTRQAELYIKELEEIVHPFDIRESKKNSDD
>Mature_316_residues
TISLQQLKYFIEVAKIGSINQAAEILYITQPSLSKSIKDIEIEVGLPLLQRSSKGISLTAEGTEFLGYARQVVEQSDLLE
ARWLDKKPSRKLCAISTQHYAFAVNAFVNMVKKTESQGIDEYEYTLREARTYEIIEDVKALRSELGILYKNSYNANVIDK
ILKENRLTFHSLFLAEPHIFVSSTNPLADRQFVSLEDLEKFPRLSYEQGEHNSFYFSEEILSTVYAKKDIKVGDRATIFN
LMIGLNGYTISTGIVSQDLNGDNIVAIPLAVDDNIEIGWISLNDFQLTRQAELYIKELEEIVHPFDIRESKKNSDD

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=26.2798634812287, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788887, Length=114, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=76, Percent_Identity=36.8421052631579, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36094; Mature: 35963

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISLQQLKYFIEVAKIGSINQAAEILYITQPSLSKSIKDIEIEVGLPLLQRSSKGISLT
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCEEEEEECCHHHHCCCCCEEEE
AEGTEFLGYARQVVEQSDLLEARWLDKKPSRKLCAISTQHYAFAVNAFVNMVKKTESQGI
ECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
DEYEYTLREARTYEIIEDVKALRSELGILYKNSYNANVIDKILKENRLTFHSLFLAEPHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEEEEECCEE
FVSSTNPLADRQFVSLEDLEKFPRLSYEQGEHNSFYFSEEILSTVYAKKDIKVGDRATIF
EEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHEE
NLMIGLNGYTISTGIVSQDLNGDNIVAIPLAVDDNIEIGWISLNDFQLTRQAELYIKELE
EHHHCCCCEEEECCCEECCCCCCCEEEEEEEECCCEEEEEEEECCEEEHHHHHHHHHHHH
EIVHPFDIRESKKNSDD
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TISLQQLKYFIEVAKIGSINQAAEILYITQPSLSKSIKDIEIEVGLPLLQRSSKGISLT
CCCHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCEEEEEECCHHHHCCCCCEEEE
AEGTEFLGYARQVVEQSDLLEARWLDKKPSRKLCAISTQHYAFAVNAFVNMVKKTESQGI
ECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
DEYEYTLREARTYEIIEDVKALRSELGILYKNSYNANVIDKILKENRLTFHSLFLAEPHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEEEEECCEE
FVSSTNPLADRQFVSLEDLEKFPRLSYEQGEHNSFYFSEEILSTVYAKKDIKVGDRATIF
EEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHEE
NLMIGLNGYTISTGIVSQDLNGDNIVAIPLAVDDNIEIGWISLNDFQLTRQAELYIKELE
EHHHCCCCEEEECCCEECCCCCCCEEEEEEEECCCEEEEEEEECCEEEHHHHHHHHHHHH
EIVHPFDIRESKKNSDD
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]