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The map label for this gene is ahpF [H]

Identifier: 125623227

GI number: 125623227

Start: 342883

End: 344409

Strand: Direct

Name: ahpF [H]

Synonym: llmg_0357

Alternate gene names: 125623227

Gene position: 342883-344409 (Clockwise)

Preceding gene: 125623226

Following gene: 125623228

Centisome position: 13.56

GC content: 38.11

Gene sequence:

>1527_bases
ATGATTTTAGATGAAAATCTGCGTTCTCAGTTACTGCCGTATATGGATTTATTAGAAAATCCAATTATTTTAAAAGTGGA
CGCAGACGATAGTGAAAATGGACAAAAAATAAATGAATTTACAGATGAACTGGCAAGTTTATCAGACTTGATTTCAAAAG
AGAAAACAAATCTGAATCATAAACCGGCTTTTTCAATTGAAAGAGAAGGTGTTTCAGGGCTTGTTTTTTCAGGTCTTCCT
TTAGGTCATGAGTTAAATTCATTGGTTTTGGCCCTTGTGCAAGTGAGTGGTCGACCACCACGTATTGAACAAGAATTAAT
TGAACAAATTAAGGCTATTAAAACTTCACTTCATTTTGATACTTATGTCAGTTTAACTTGTCATAATTGTCCAGATGTGG
TTCAAGCTTTAAATACAATGACCATTCTCAACCCTAACATTAGTCATACCATGATTGAGGGAGGCATGTTCCAAGCAGAA
GTAGAAGCAAAAGGAATTATGGCTGTTCCTGCTGTCTTTAAAAATGGCGAAGAATTTCATAGTGGACGAGCAAGTCTTGA
AGAATTGTTGGAAAAAATTACAGGTCCAGAAAGTTCGGATAGTTTCGCAGAAAAAGAACCTTATGATGTTTTGGTAGTAG
GAGGGGGGCCAGCTGGTGCGAGTGCAGCTATTTATGCGGCACGTAAGGGAATCAGGACAGGATTGATTGCCGAGCGCTTT
GGAGGCCAACCTTTAGAAACTTTAGGGATTGAAAATCTGATTGGAACACCCTATATAGAGGGTGTTCAGCTTGGTCGTCA
GCTTGAAGAACACGTAAAAAAATATCCAGTAGATTTGATGAATCTGCAAAAAGCAGTTAAACTTGAGAAAAAAGATTTAA
TTGAAGTAAGTCTTGCAAATGGAGCAACCTTGAAGAGTAAAGCTGTTATTCTCTCAACTGGCGCTCGTTGGCGTGATTTA
GGAATCCCAGGAGAACAACGCTTTAAGAATAAAGGAGTGGCTTATTGTCCTCATTGTGATGGTCCGCTTTTCTCTGGTAA
AGATGTGGCAGTTATTGGTGGAGGAAATTCAGGGATTGAAGCAGCGATAGACTTAGCTGGTTTGGTCAACCATGTCACTG
TTCTTGAATTTTTACCAGAACTTAAAGCAGATAAAATCTTACAAAAAAAACTTGCTAGTCTAACTAATGTTACTGTTTTG
ACCAATGTGGAAACTAAAGAGATTCTAGGAGATGAGCAAGTCACGGGGTTGAATTATCAAGTTCGAGGCTCTAAAGAAAC
GATTCATTTAGAACTTGCCGGTGTCTTTGTTTTGATTGGTTTAGTTCCCAATACTCAGTGGTTGGAAGGGACAATTGATT
TGACAGATCGTCATGAAATTGTGACTGATAAGGTTGGAGCAACAAATATTCCTGGTGTCTTTGCAGCAGGAGATTGTACA
GATACTGTTTATAAACAAATTATTGTGTCAATGGGAAGTGGAGCGACTGCTTCCTTAGGTGCCTTTGATTATTTGATAAG
AAATTAA

Upstream 100 bases:

>100_bases
TTCATGTAGGAATTGACCTTGTAGGAAAAATTTAAAATAAATAAGTGAGTCTTGACTCACTTTATTTGTCTTGAAAAATT
TAATGACAGAAAGGTTTAAT

Downstream 100 bases:

>100_bases
GTTGTTTTTCTTAAAAAGGAAGCTTGTCTGAGTTTCCTTTTTTAGTCTTTTCATTTTTCTTGATTAAGTTGCGTTTCTCG
ATTAAACTAGAACTAATCAA

Product: alkyl hydroperoxide reductase subunit F

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MILDENLRSQLLPYMDLLENPIILKVDADDSENGQKINEFTDELASLSDLISKEKTNLNHKPAFSIEREGVSGLVFSGLP
LGHELNSLVLALVQVSGRPPRIEQELIEQIKAIKTSLHFDTYVSLTCHNCPDVVQALNTMTILNPNISHTMIEGGMFQAE
VEAKGIMAVPAVFKNGEEFHSGRASLEELLEKITGPESSDSFAEKEPYDVLVVGGGPAGASAAIYAARKGIRTGLIAERF
GGQPLETLGIENLIGTPYIEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLANGATLKSKAVILSTGARWRDL
GIPGEQRFKNKGVAYCPHCDGPLFSGKDVAVIGGGNSGIEAAIDLAGLVNHVTVLEFLPELKADKILQKKLASLTNVTVL
TNVETKEILGDEQVTGLNYQVRGSKETIHLELAGVFVLIGLVPNTQWLEGTIDLTDRHEIVTDKVGATNIPGVFAAGDCT
DTVYKQIIVSMGSGATASLGAFDYLIRN

Sequences:

>Translated_508_residues
MILDENLRSQLLPYMDLLENPIILKVDADDSENGQKINEFTDELASLSDLISKEKTNLNHKPAFSIEREGVSGLVFSGLP
LGHELNSLVLALVQVSGRPPRIEQELIEQIKAIKTSLHFDTYVSLTCHNCPDVVQALNTMTILNPNISHTMIEGGMFQAE
VEAKGIMAVPAVFKNGEEFHSGRASLEELLEKITGPESSDSFAEKEPYDVLVVGGGPAGASAAIYAARKGIRTGLIAERF
GGQPLETLGIENLIGTPYIEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLANGATLKSKAVILSTGARWRDL
GIPGEQRFKNKGVAYCPHCDGPLFSGKDVAVIGGGNSGIEAAIDLAGLVNHVTVLEFLPELKADKILQKKLASLTNVTVL
TNVETKEILGDEQVTGLNYQVRGSKETIHLELAGVFVLIGLVPNTQWLEGTIDLTDRHEIVTDKVGATNIPGVFAAGDCT
DTVYKQIIVSMGSGATASLGAFDYLIRN
>Mature_508_residues
MILDENLRSQLLPYMDLLENPIILKVDADDSENGQKINEFTDELASLSDLISKEKTNLNHKPAFSIEREGVSGLVFSGLP
LGHELNSLVLALVQVSGRPPRIEQELIEQIKAIKTSLHFDTYVSLTCHNCPDVVQALNTMTILNPNISHTMIEGGMFQAE
VEAKGIMAVPAVFKNGEEFHSGRASLEELLEKITGPESSDSFAEKEPYDVLVVGGGPAGASAAIYAARKGIRTGLIAERF
GGQPLETLGIENLIGTPYIEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLANGATLKSKAVILSTGARWRDL
GIPGEQRFKNKGVAYCPHCDGPLFSGKDVAVIGGGNSGIEAAIDLAGLVNHVTVLEFLPELKADKILQKKLASLTNVTVL
TNVETKEILGDEQVTGLNYQVRGSKETIHLELAGVFVLIGLVPNTQWLEGTIDLTDRHEIVTDKVGATNIPGVFAAGDCT
DTVYKQIIVSMGSGATASLGAFDYLIRN

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=517, Percent_Identity=53.1914893617021, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=36.8932038834951, Blast_Score=168, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=32.2683706070287, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=34.0836012861736, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 54829; Mature: 54829

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDENLRSQLLPYMDLLENPIILKVDADDSENGQKINEFTDELASLSDLISKEKTNLNH
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KPAFSIEREGVSGLVFSGLPLGHELNSLVLALVQVSGRPPRIEQELIEQIKAIKTSLHFD
CCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCEE
TYVSLTCHNCPDVVQALNTMTILNPNISHTMIEGGMFQAEVEAKGIMAVPAVFKNGEEFH
EEEEEEECCCHHHHHHHHHEEEECCCCCHHEECCCEEEEEECCCCEEEEHHHHCCCHHHH
SGRASLEELLEKITGPESSDSFAEKEPYDVLVVGGGPAGASAAIYAARKGIRTGLIAERF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHH
GGQPLETLGIENLIGTPYIEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLAN
CCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHEEEEEECC
GATLKSKAVILSTGARWRDLGIPGEQRFKNKGVAYCPHCDGPLFSGKDVAVIGGGNSGIE
CCEECCCEEEEECCCCEEECCCCCHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCCCHH
AAIDLAGLVNHVTVLEFLPELKADKILQKKLASLTNVTVLTNVETKEILGDEQVTGLNYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCEECCEEE
VRGSKETIHLELAGVFVLIGLVPNTQWLEGTIDLTDRHEIVTDKVGATNIPGVFAAGDCT
EECCCCEEEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCEEECCCCH
DTVYKQIIVSMGSGATASLGAFDYLIRN
HHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MILDENLRSQLLPYMDLLENPIILKVDADDSENGQKINEFTDELASLSDLISKEKTNLNH
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KPAFSIEREGVSGLVFSGLPLGHELNSLVLALVQVSGRPPRIEQELIEQIKAIKTSLHFD
CCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCEE
TYVSLTCHNCPDVVQALNTMTILNPNISHTMIEGGMFQAEVEAKGIMAVPAVFKNGEEFH
EEEEEEECCCHHHHHHHHHEEEECCCCCHHEECCCEEEEEECCCCEEEEHHHHCCCHHHH
SGRASLEELLEKITGPESSDSFAEKEPYDVLVVGGGPAGASAAIYAARKGIRTGLIAERF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHH
GGQPLETLGIENLIGTPYIEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLAN
CCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHEEEEEECC
GATLKSKAVILSTGARWRDLGIPGEQRFKNKGVAYCPHCDGPLFSGKDVAVIGGGNSGIE
CCEECCCEEEEECCCCEEECCCCCHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCCCHH
AAIDLAGLVNHVTVLEFLPELKADKILQKKLASLTNVTVLTNVETKEILGDEQVTGLNYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCEECCEEE
VRGSKETIHLELAGVFVLIGLVPNTQWLEGTIDLTDRHEIVTDKVGATNIPGVFAAGDCT
EECCCCEEEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCEEECCCCH
DTVYKQIIVSMGSGATASLGAFDYLIRN
HHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1917890; 2760020 [H]