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The map label for this gene is ahpC [H]

Identifier: 125623226

GI number: 125623226

Start: 342254

End: 342817

Strand: Direct

Name: ahpC [H]

Synonym: llmg_0356

Alternate gene names: 125623226

Gene position: 342254-342817 (Clockwise)

Preceding gene: 125623225

Following gene: 125623227

Centisome position: 13.53

GC content: 37.59

Gene sequence:

>564_bases
ATGTCACTAGTTGGTAAAAAAATAGAAGAATTTTCAACAGATGCTTATCTTGGTGGGAAATTTATTAAAGTTTCTGACAA
AGATTTTTATGGAAAATGGAATGTACTTTGTTTCTATCCAGCGGACTTTTCATTTGTTTGCCCGACAGAGTTAGAAGATT
TGGAAGAAACATATCCTGAATTGAAAAAACTCGGAGTAGAAGTTTACTCTGCTTCAACAGATACTCATTTTGTTCATGCT
GCATGGCATGACCATAGCGATGCAATTTCTAAGATTACTTATCCTATGCTTGCGGACCCTTCACAAAAAATTTCACGGGC
TTTTGATGTTCTTGATGAAGAAGCTGGACTTGCTCAACGTGGAACACTTATTATTGACCCTGATGGTGTGATTCAAGCTT
TTGAAATTACAGCAGATGGAATTGGGCGAGATGCTAGTCAGTTAATTGATAAAATTAAGGCAGCCCAATATGTCCGCAAT
CATCCAGGTGAAGTTTGTCCCGCTAAGTGGAAAGAAGATGGGGAAAGCCTTCATGTAGGAATTGACCTTGTAGGAAAAAT
TTAA

Upstream 100 bases:

>100_bases
AATTTAATAGTTTGTGAGTTTTTAGACAAATTAATTGATTCTTCATTTTTTTCTTGAGATAATTTAATAGTAAAGTTTTA
AACAAAAAAAGGAGAACATC

Downstream 100 bases:

>100_bases
AATAAATAAGTGAGTCTTGACTCACTTTATTTGTCTTGAAAAATTTAATGACAGAAAGGTTTAATATGATTTTAGATGAA
AATCTGCGTTCTCAGTTACT

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLVGKKIEEFSTDAYLGGKFIKVSDKDFYGKWNVLCFYPADFSFVCPTELEDLEETYPELKKLGVEVYSASTDTHFVHA
AWHDHSDAISKITYPMLADPSQKISRAFDVLDEEAGLAQRGTLIIDPDGVIQAFEITADGIGRDASQLIDKIKAAQYVRN
HPGEVCPAKWKEDGESLHVGIDLVGKI

Sequences:

>Translated_187_residues
MSLVGKKIEEFSTDAYLGGKFIKVSDKDFYGKWNVLCFYPADFSFVCPTELEDLEETYPELKKLGVEVYSASTDTHFVHA
AWHDHSDAISKITYPMLADPSQKISRAFDVLDEEAGLAQRGTLIIDPDGVIQAFEITADGIGRDASQLIDKIKAAQYVRN
HPGEVCPAKWKEDGESLHVGIDLVGKI
>Mature_186_residues
SLVGKKIEEFSTDAYLGGKFIKVSDKDFYGKWNVLCFYPADFSFVCPTELEDLEETYPELKKLGVEVYSASTDTHFVHAA
WHDHSDAISKITYPMLADPSQKISRAFDVLDEEAGLAQRGTLIIDPDGVIQAFEITADGIGRDASQLIDKIKAAQYVRNH
PGEVCPAKWKEDGESLHVGIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=170, Percent_Identity=40, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI5802974, Length=170, Percent_Identity=40, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=3e-30,
Organism=Homo sapiens, GI4505591, Length=178, Percent_Identity=33.7078651685393, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI32455266, Length=178, Percent_Identity=33.7078651685393, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI32455264, Length=178, Percent_Identity=33.7078651685393, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5453549, Length=177, Percent_Identity=32.7683615819209, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI33188454, Length=82, Percent_Identity=41.4634146341463, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=58.2887700534759, Blast_Score=241, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=38.9830508474576, Blast_Score=138, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=37.7049180327869, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=37.7049180327869, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323613, Length=173, Percent_Identity=35.2601156069364, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320661, Length=170, Percent_Identity=32.9411764705882, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319407, Length=174, Percent_Identity=26.4367816091954, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357347, Length=189, Percent_Identity=36.5079365079365, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17738015, Length=183, Percent_Identity=36.6120218579235, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656348, Length=179, Percent_Identity=35.195530726257, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17864676, Length=179, Percent_Identity=35.195530726257, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24581278, Length=163, Percent_Identity=27.6073619631902, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20758; Mature: 20626

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVGKKIEEFSTDAYLGGKFIKVSDKDFYGKWNVLCFYPADFSFVCPTELEDLEETYPE
CCCCHHHHHHHCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHH
LKKLGVEVYSASTDTHFVHAAWHDHSDAISKITYPMLADPSQKISRAFDVLDEEAGLAQR
HHHHCHHEEECCCCCEEEEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GTLIIDPDGVIQAFEITADGIGRDASQLIDKIKAAQYVRNHPGEVCPAKWKEDGESLHVG
CEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
IDLVGKI
EEEECCC
>Mature Secondary Structure 
SLVGKKIEEFSTDAYLGGKFIKVSDKDFYGKWNVLCFYPADFSFVCPTELEDLEETYPE
CCCHHHHHHHCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHH
LKKLGVEVYSASTDTHFVHAAWHDHSDAISKITYPMLADPSQKISRAFDVLDEEAGLAQR
HHHHCHHEEECCCCCEEEEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GTLIIDPDGVIQAFEITADGIGRDASQLIDKIKAAQYVRNHPGEVCPAKWKEDGESLHVG
CEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
IDLVGKI
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA