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The map label for this gene is trpF [H]

Identifier: 124486212

GI number: 124486212

Start: 1424960

End: 1425538

Strand: Reverse

Name: trpF [H]

Synonym: Mlab_1395

Alternate gene names: 124486212

Gene position: 1425538-1424960 (Counterclockwise)

Preceding gene: 124486213

Following gene: 124486211

Centisome position: 78.98

GC content: 51.99

Gene sequence:

>579_bases
ATGCGTGTAAAAATCTGCGGGATCACCACGGTAAGGGATGCGTTAATCGCGGAAGAAGAGGGTGCCGACGCGATTGGAAT
CGTCGTCTGTTCGGATTCCAAACGTTCGGTTCCGGTCAGCCGGGCAAGAGAGATATTCGCCGCCCTTCGTCCAAACACCG
AGAAGATCTGCGTTACCAATACAGACAGTCAAAGCGATCTGGAACTCATCCTCTCCCTCAAACCGACCGCCATTCAGATT
CCCCAAAATCTGAAAGTCCCGGCAGGTGTTGGAACAAAAATTTACCGTGTGGCGTCGGGAGAGGCCAGCATCTCCGAGAA
ATGCGATGCGGTTGTAATCGATCAGAGCTGCGGCCGGGGAATCGTGTATGACCGGAGTTATGCCCAAAAAGTAGTTGAAA
AGTCGGCGGTTCCCGTTATACTTGCCGGCGGCCTGACGCCCGACAACGTCGGCGATGCCATACGGGATCTTCGTCTGTAT
GCCGTCGACGTCTCATCCGGCGTTGAAAAATCAAAGGGAATCAAAGACAGAAAAAAGATGCGTGAATTTATAGAAATTTG
CAGGAGACCAGCAGTATGA

Upstream 100 bases:

>100_bases
CTGAGGATGTCCTTGGTCTGAAAAATTTATGTGACGGTTTTCTCATTGGAACCTCTCTCATGAAGTCTGCAGATCCGCAA
AAAACTTTGGAGGCATTCGT

Downstream 100 bases:

>100_bases
AAGAAAAAACAGGATATTATGGAGAGTTCGGCGGAAGATTCGTCCCCGAAACACTCATGGCGGCTCTCTACGAGCTGGAC
AGCGCGTACCACAGATTAAA

Product: PfkB

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRVKICGITTVRDALIAEEEGADAIGIVVCSDSKRSVPVSRAREIFAALRPNTEKICVTNTDSQSDLELILSLKPTAIQI
PQNLKVPAGVGTKIYRVASGEASISEKCDAVVIDQSCGRGIVYDRSYAQKVVEKSAVPVILAGGLTPDNVGDAIRDLRLY
AVDVSSGVEKSKGIKDRKKMREFIEICRRPAV

Sequences:

>Translated_192_residues
MRVKICGITTVRDALIAEEEGADAIGIVVCSDSKRSVPVSRAREIFAALRPNTEKICVTNTDSQSDLELILSLKPTAIQI
PQNLKVPAGVGTKIYRVASGEASISEKCDAVVIDQSCGRGIVYDRSYAQKVVEKSAVPVILAGGLTPDNVGDAIRDLRLY
AVDVSSGVEKSKGIKDRKKMREFIEICRRPAV
>Mature_192_residues
MRVKICGITTVRDALIAEEEGADAIGIVVCSDSKRSVPVSRAREIFAALRPNTEKICVTNTDSQSDLELILSLKPTAIQI
PQNLKVPAGVGTKIYRVASGEASISEKCDAVVIDQSCGRGIVYDRSYAQKVVEKSAVPVILAGGLTPDNVGDAIRDLRLY
AVDVSSGVEKSKGIKDRKKMREFIEICRRPAV

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 20702; Mature: 20702

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKICGITTVRDALIAEEEGADAIGIVVCSDSKRSVPVSRAREIFAALRPNTEKICVTN
CEEEEEECHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
TDSQSDLELILSLKPTAIQIPQNLKVPAGVGTKIYRVASGEASISEKCDAVVIDQSCGRG
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCC
IVYDRSYAQKVVEKSAVPVILAGGLTPDNVGDAIRDLRLYAVDVSSGVEKSKGIKDRKKM
EEECHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHEEEEEEECCCCCCHHCCCHHHHHH
REFIEICRRPAV
HHHHHHHCCCCC
>Mature Secondary Structure
MRVKICGITTVRDALIAEEEGADAIGIVVCSDSKRSVPVSRAREIFAALRPNTEKICVTN
CEEEEEECHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
TDSQSDLELILSLKPTAIQIPQNLKVPAGVGTKIYRVASGEASISEKCDAVVIDQSCGRG
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCC
IVYDRSYAQKVVEKSAVPVILAGGLTPDNVGDAIRDLRLYAVDVSSGVEKSKGIKDRKKM
EEECHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHEEEEEEECCCCCCHHCCCHHHHHH
REFIEICRRPAV
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA