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The map label for this gene is rpoH

Identifier: 124485984

GI number: 124485984

Start: 1185475

End: 1185723

Strand: Reverse

Name: rpoH

Synonym: Mlab_1164

Alternate gene names: 124485984

Gene position: 1185723-1185475 (Counterclockwise)

Preceding gene: 124485988

Following gene: 124485983

Centisome position: 65.69

GC content: 46.59

Gene sequence:

>249_bases
ATGACAAGACTCAATGTATTACTGCATGAGATGGTCCCCGACCATCAGATCATGACTGACGAAGACGTCAAAAATCTTCT
CACAACCTTCGACATCACGGAAGATCACCTTCCAAAAATCTATCATGATGACCCGGCTGTAAAAGCCTGCGGCGCAAAAC
CCGGAAACGTCATTATGATCGTAAGAAAGAGCCAGACAGCAGGCGAAGCCACATCCTACCGCCTTGTCGTTAGAAGGCCG
AAAAAATAA

Upstream 100 bases:

>100_bases
CATTCACAAGCCAAAGAACCAGACTTTTAAAAATTGAACCAGCTACCTGAAAGAATCAGCAGCAAGACCCCGTATTCACA
CGAATCTGATTAGGAGCTAC

Downstream 100 bases:

>100_bases
CCGGAGGCAGAAATCATGATCGACAGAAGTGTATTATCAGGCGCGTACTTTTCCCAGGAACACGTTGCACGCCACCAGCT
GGACTCCTATAACAATTTTG

Product: DNA-directed RNA polymerase subunit H

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MTRLNVLLHEMVPDHQIMTDEDVKNLLTTFDITEDHLPKIYHDDPAVKACGAKPGNVIMIVRKSQTAGEATSYRLVVRRP
KK

Sequences:

>Translated_82_residues
MTRLNVLLHEMVPDHQIMTDEDVKNLLTTFDITEDHLPKIYHDDPAVKACGAKPGNVIMIVRKSQTAGEATSYRLVVRRP
KK
>Mature_81_residues
TRLNVLLHEMVPDHQIMTDEDVKNLLTTFDITEDHLPKIYHDDPAVKACGAKPGNVIMIVRKSQTAGEATSYRLVVRRPK
K

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG2012

COG function: function code K; DNA-directed RNA polymerase, subunit H, RpoH/RPB5

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family

Homologues:

Organism=Homo sapiens, GI14589951, Length=73, Percent_Identity=43.8356164383562, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507947, Length=74, Percent_Identity=40.5405405405405, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319630, Length=74, Percent_Identity=36.4864864864865, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922004, Length=73, Percent_Identity=42.4657534246575, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOH_METLZ (A2SSM7)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030600.1
- ProteinModelPortal:   A2SSM7
- SMR:   A2SSM7
- STRING:   A2SSM7
- GeneID:   4794741
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_1164
- eggNOG:   arNOG12569
- HOGENOM:   HBG496846
- OMA:   IKRKSPT
- ProtClustDB:   PRK09570
- BioCyc:   MLAB410358:MLAB_1164-MONOMER
- HAMAP:   MF_00025
- InterPro:   IPR020609
- InterPro:   IPR000783
- Gene3D:   G3DSA:3.90.940.20
- ProDom:   PD005155

Pfam domain/function: PF01191 RNA_pol_Rpb5_C; SSF55287 RNApol_RPB5_like

EC number: =2.7.7.6

Molecular weight: Translated: 9312; Mature: 9181

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS01110 RNA_POL_H_23KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLNVLLHEMVPDHQIMTDEDVKNLLTTFDITEDHLPKIYHDDPAVKACGAKPGNVIMI
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCEECCCCCCCEEEE
VRKSQTAGEATSYRLVVRRPKK
EECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TRLNVLLHEMVPDHQIMTDEDVKNLLTTFDITEDHLPKIYHDDPAVKACGAKPGNVIMI
CHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCEECCCCCCCEEEE
VRKSQTAGEATSYRLVVRRPKK
EECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA