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The map label for this gene is ttdA [C]

Identifier: 124485359

GI number: 124485359

Start: 507686

End: 508507

Strand: Reverse

Name: ttdA [C]

Synonym: Mlab_0534

Alternate gene names: 124485359

Gene position: 508507-507686 (Counterclockwise)

Preceding gene: 124485362

Following gene: 124485358

Centisome position: 28.17

GC content: 57.3

Gene sequence:

>822_bases
ATGGACCCCCTCTACAACCGTCTTGCATCCGCCGTGGAAGAGGCAATTCACCAGGCCGAGACGATCCTTCCGCCCGACGT
GGAGGAAGCACTGCATACTGCATACAATAAAGAAACCAACCCGACCGCACGCGGCGAGTTTGAAAATATCTTCGCCAATC
TCCAGGTCGCCCGGGAGAAAAACGTGCCCATCTGTCAGGACACCGGGATTTTCGTCATCTACCTGACCATTCCAGAAACC
GTTCCGCTGACCACAAAGCTCTACGACGCCGTAAGCGAAGGGATCCGTCTCGCAACAAAATCCGTCCCTCTCCGGCCAAA
CGCGGTCCATCCCCTCACCCGGAAAAACTCGGGCGACAACACCGGGGCGGGGATCCCGGCAGTCCATATCCTTCCGGGCG
ATACGCTCCGGGTCACCGTATTCCCCAAAGGAGCAGGTTCGGAAAACATGTCCCAGATCAGAATGATGCTCCCTTCCGAG
ATCTCCAGGATCCCGGAGTTTGTGACCTCGGTCGTCAAAGATGCGGGCTCCCGTCCGTGTCCCCCGATAGTCGTAGGGGT
CGGTATCGGCGGAACCTTCGACTCGGCCGCATCCTTTGCAAAAGAAGCGCTCCTCTCGCCGATAAACAGCATGACCGCCT
TCGAACAGAAGATATGCGATTCGATCAACCAGCTCGGCATCGGCGTTATGGGACTTGGCGGCGACACGACCTGTCTCGCC
GTCAAGGTAAAAGAAGGGGCATGCCACACGGCTTCGCTTCCCGTCGCCGTAAATATTCAGTGCTGGTGTTCTAGACGCGG
TGTTGTTGAGGTGGAACTATGA

Upstream 100 bases:

>100_bases
AAAATTCACATCCTCTCATACGGCATTTCCATTGGACCGCTCTCCCGCCGTCTTTTTTAATGAAAACCATTAATCCCTAT
CTCATCTAAACAGATATACC

Downstream 100 bases:

>100_bases
TCCGGCTGACGACCCCCCTCGGAGAGGAAGTTCTCGATCTCCATGCGGGAGACCGGGTCCTTCTTTCCGGGACCATTTAC
ACTGCACGCGACGAAGCCCA

Product: fumarase alpha subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDPLYNRLASAVEEAIHQAETILPPDVEEALHTAYNKETNPTARGEFENIFANLQVAREKNVPICQDTGIFVIYLTIPET
VPLTTKLYDAVSEGIRLATKSVPLRPNAVHPLTRKNSGDNTGAGIPAVHILPGDTLRVTVFPKGAGSENMSQIRMMLPSE
ISRIPEFVTSVVKDAGSRPCPPIVVGVGIGGTFDSAASFAKEALLSPINSMTAFEQKICDSINQLGIGVMGLGGDTTCLA
VKVKEGACHTASLPVAVNIQCWCSRRGVVEVEL

Sequences:

>Translated_273_residues
MDPLYNRLASAVEEAIHQAETILPPDVEEALHTAYNKETNPTARGEFENIFANLQVAREKNVPICQDTGIFVIYLTIPET
VPLTTKLYDAVSEGIRLATKSVPLRPNAVHPLTRKNSGDNTGAGIPAVHILPGDTLRVTVFPKGAGSENMSQIRMMLPSE
ISRIPEFVTSVVKDAGSRPCPPIVVGVGIGGTFDSAASFAKEALLSPINSMTAFEQKICDSINQLGIGVMGLGGDTTCLA
VKVKEGACHTASLPVAVNIQCWCSRRGVVEVEL
>Mature_273_residues
MDPLYNRLASAVEEAIHQAETILPPDVEEALHTAYNKETNPTARGEFENIFANLQVAREKNVPICQDTGIFVIYLTIPET
VPLTTKLYDAVSEGIRLATKSVPLRPNAVHPLTRKNSGDNTGAGIPAVHILPGDTLRVTVFPKGAGSENMSQIRMMLPSE
ISRIPEFVTSVVKDAGSRPCPPIVVGVGIGGTFDSAASFAKEALLSPINSMTAFEQKICDSINQLGIGVMGLGGDTTCLA
VKVKEGACHTASLPVAVNIQCWCSRRGVVEVEL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=277, Percent_Identity=31.4079422382672, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29135; Mature: 29135

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLYNRLASAVEEAIHQAETILPPDVEEALHTAYNKETNPTARGEFENIFANLQVAREK
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCC
NVPICQDTGIFVIYLTIPETVPLTTKLYDAVSEGIRLATKSVPLRPNAVHPLTRKNSGDN
CCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCC
TGAGIPAVHILPGDTLRVTVFPKGAGSENMSQIRMMLPSEISRIPEFVTSVVKDAGSRPC
CCCCCCEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPIVVGVGIGGTFDSAASFAKEALLSPINSMTAFEQKICDSINQLGIGVMGLGGDTTCLA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEE
VKVKEGACHTASLPVAVNIQCWCSRRGVVEVEL
EEEECCCCCCCCCCEEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MDPLYNRLASAVEEAIHQAETILPPDVEEALHTAYNKETNPTARGEFENIFANLQVAREK
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCC
NVPICQDTGIFVIYLTIPETVPLTTKLYDAVSEGIRLATKSVPLRPNAVHPLTRKNSGDN
CCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCC
TGAGIPAVHILPGDTLRVTVFPKGAGSENMSQIRMMLPSEISRIPEFVTSVVKDAGSRPC
CCCCCCEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPIVVGVGIGGTFDSAASFAKEALLSPINSMTAFEQKICDSINQLGIGVMGLGGDTTCLA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEE
VKVKEGACHTASLPVAVNIQCWCSRRGVVEVEL
EEEECCCCCCCCCCEEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]