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The map label for this gene is ttdB [C]

Identifier: 124485358

GI number: 124485358

Start: 507186

End: 507689

Strand: Reverse

Name: ttdB [C]

Synonym: Mlab_0533

Alternate gene names: 124485358

Gene position: 507689-507186 (Counterclockwise)

Preceding gene: 124485359

Following gene: 124485355

Centisome position: 28.13

GC content: 55.16

Gene sequence:

>504_bases
ATGATCCGGCTGACGACCCCCCTCGGAGAGGAAGTTCTCGATCTCCATGCGGGAGACCGGGTCCTTCTTTCCGGGACCAT
TTACACTGCACGCGACGAAGCCCACCTGAAAATACGTGAAGAGGGCTTCCCCTTCGATCCGAAAGGCGCGGTGATTTATC
ACTGCGGCCCGGTCATCGACGAAGCACAGAATAAAGTCGTCGCCGCCGGCCCCACAACCTCCGCACGGATGAATAATCTC
ACAAAATTCATGCTCGATGCAGGTGTTCGGGGCCTGATTGGAAAAGGCGGAATGTCGGAGATCGTTCGTGAAGAACTTCG
GGGAAGAGCGGTCTATTTTGCCTTCACCGGAGGATGCGCCGCTCTCGCCGCTTCATGCATGGAGCTTGCCGGTTGTCATT
ATCCGGAACTTGGCATGGCAGAAGGAATCTGGGAAATCAAACTGACCGATCTTCCGGTAGTCGTCGGAATAGATGCTCAC
GGCGGCGATCTTTTCGTAAGATAA

Upstream 100 bases:

>100_bases
CCGTCAAGGTAAAAGAAGGGGCATGCCACACGGCTTCGCTTCCCGTCGCCGTAAATATTCAGTGCTGGTGTTCTAGACGC
GGTGTTGTTGAGGTGGAACT

Downstream 100 bases:

>100_bases
CTCAGATGAGCCCTGCCGTGACCAAAGCCAGGCAGATGAGAAGAGCCAAAATCCCGCCCGATAATGTGGCGAGGAGATTG
GTTCCCGAATTCCCGATAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MIRLTTPLGEEVLDLHAGDRVLLSGTIYTARDEAHLKIREEGFPFDPKGAVIYHCGPVIDEAQNKVVAAGPTTSARMNNL
TKFMLDAGVRGLIGKGGMSEIVREELRGRAVYFAFTGGCAALAASCMELAGCHYPELGMAEGIWEIKLTDLPVVVGIDAH
GGDLFVR

Sequences:

>Translated_167_residues
MIRLTTPLGEEVLDLHAGDRVLLSGTIYTARDEAHLKIREEGFPFDPKGAVIYHCGPVIDEAQNKVVAAGPTTSARMNNL
TKFMLDAGVRGLIGKGGMSEIVREELRGRAVYFAFTGGCAALAASCMELAGCHYPELGMAEGIWEIKLTDLPVVVGIDAH
GGDLFVR
>Mature_167_residues
MIRLTTPLGEEVLDLHAGDRVLLSGTIYTARDEAHLKIREEGFPFDPKGAVIYHCGPVIDEAQNKVVAAGPTTSARMNNL
TKFMLDAGVRGLIGKGGMSEIVREELRGRAVYFAFTGGCAALAASCMELAGCHYPELGMAEGIWEIKLTDLPVVVGIDAH
GGDLFVR

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=171, Percent_Identity=37.4269005847953, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787897, Length=178, Percent_Identity=32.5842696629214, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790564, Length=176, Percent_Identity=32.3863636363636, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 17901; Mature: 17901

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLTTPLGEEVLDLHAGDRVLLSGTIYTARDEAHLKIREEGFPFDPKGAVIYHCGPVID
CEEECCCCCHHHHHHCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEECCCCHH
EAQNKVVAAGPTTSARMNNLTKFMLDAGVRGLIGKGGMSEIVREELRGRAVYFAFTGGCA
HCCCCEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCEEEEEEECCHH
ALAASCMELAGCHYPELGMAEGIWEIKLTDLPVVVGIDAHGGDLFVR
HHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCEEEEC
>Mature Secondary Structure
MIRLTTPLGEEVLDLHAGDRVLLSGTIYTARDEAHLKIREEGFPFDPKGAVIYHCGPVID
CEEECCCCCHHHHHHCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEECCCCHH
EAQNKVVAAGPTTSARMNNLTKFMLDAGVRGLIGKGGMSEIVREELRGRAVYFAFTGGCA
HCCCCEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCEEEEEEECCHH
ALAASCMELAGCHYPELGMAEGIWEIKLTDLPVVVGIDAHGGDLFVR
HHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]