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The map label for this gene is degP [H]

Identifier: 124266037

GI number: 124266037

Start: 879642

End: 880802

Strand: Reverse

Name: degP [H]

Synonym: Mpe_A0844

Alternate gene names: 124266037

Gene position: 880802-879642 (Counterclockwise)

Preceding gene: 124266040

Following gene: 124266018

Centisome position: 21.78

GC content: 69.6

Gene sequence:

>1161_bases
ATGCGCAAGACCTGGTTGATTTTCTCCCAAGCCGTGACGGTCGCCCTGGCGATGTGGTTCGTCGTGGCCACGCTCAAGCC
CGAATGGGTGCAGAACAGGCCGCTGTCGACTGCGGTGGGGTCGTCGTCCAACCCGGCCCCTCAGATCACGCTGGCACCCG
CCGCAGCCGGCGGCAGCAGCTACGCCGCCGCGGCCAAGCGCGCGGCGCCGGCGGTGGTGAGCGTCATCACGAGCAAGACA
CCGACCGCGCGCGATCCGCGCGCCGCCGATCCCTGGTTCCGCTATTTCTTCGGTGATCCCGACTCGCAGGCGCAGAGCGG
CGTGGGCTCGGGCGTCATCGTTTCGCCCGAAGGCTATGTGCTGACCAACAACCACGTGGTCGAGCGCATGGACGACATCG
AGGTCGTGCTGTCCGACGGGCGGCGCACCAAGGCCGAGGTGATCGGCACCGACCCCGAGGCCGACCTCGCGGTGCTGCGC
ATCAAGCTCGACAAGCTGCCGTCGGTGAGCTTCGGGGACTCCGACGCACTGCAGGTCGGCGACGTGGTGCTGGCGATCGG
CAACCCCTTCGGCGTCGGCCAGACGGTCACCTCCGGCATCGTGTCGGCGCTCGGCCGCAACCAGCTCGGCATCAACACCT
TCGAGAACTTCATCCAGACCGACGCGGCCATCAACCCCGGCAATTCCGGCGGGGCGCTGATCGACGCCGCCGGCAACCTG
ATGGGGATCAACACAGCGATCTACTCGCGCTCGGGCGGCAGCCTCGGCATCGGCTTCGCGATCCCGGTGTCCACGGCCCG
CCAGGTGATGGAGGGCCTGATCCGGGACGGCCAGGTCACGCGCGGCTGGATCGGCGTGGAGCCACGCGACCTCACGCCCG
AGATCGCCGAGACCTTCAACCTCAAGGTGTCGCAGGGCGTGCTGATCACCGGCGTGCTGCAGGGCGGCCCGGCCAGCGAC
GGCGGCCTGCGGCCCGGCGACGTGGTGGTGAAGGTGGCCGACTCGCCGGTCGGCAACACCTCGCAGCTGCTCAACGTCGT
GGCCTCCCTCAAGCCGCGCTCGAAGGCCCGGCTCGTGGTGCAACGGGGCGACAGCGAAGTGACGCTCGACGTCATCGTCG
CGCAGCGGCCGAAGGCACCGCGGCAGCAGCGCGAACCCTAG

Upstream 100 bases:

>100_bases
CCTGCAAACCGTTCGGCCCATAATCCTTGAACCGCTCGAGTTCGAGCAGCGTGGACAGGTAGTTTTCCAGCTCTTCACGG
CTCGTCAATTCTTCTCTCCC

Downstream 100 bases:

>100_bases
ACGGCGCCGTCCTCGGCCGCCGCATCGGGCGCCTGGGTGTGCTTGATGAACACCTTGGCGGCCCAGATCCCGATCTCGTA
GAGGATGCACATCGGGATCG

Product: putative HtrA-like serine protease signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRKTWLIFSQAVTVALAMWFVVATLKPEWVQNRPLSTAVGSSSNPAPQITLAPAAAGGSSYAAAAKRAAPAVVSVITSKT
PTARDPRAADPWFRYFFGDPDSQAQSGVGSGVIVSPEGYVLTNNHVVERMDDIEVVLSDGRRTKAEVIGTDPEADLAVLR
IKLDKLPSVSFGDSDALQVGDVVLAIGNPFGVGQTVTSGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALIDAAGNL
MGINTAIYSRSGGSLGIGFAIPVSTARQVMEGLIRDGQVTRGWIGVEPRDLTPEIAETFNLKVSQGVLITGVLQGGPASD
GGLRPGDVVVKVADSPVGNTSQLLNVVASLKPRSKARLVVQRGDSEVTLDVIVAQRPKAPRQQREP

Sequences:

>Translated_386_residues
MRKTWLIFSQAVTVALAMWFVVATLKPEWVQNRPLSTAVGSSSNPAPQITLAPAAAGGSSYAAAAKRAAPAVVSVITSKT
PTARDPRAADPWFRYFFGDPDSQAQSGVGSGVIVSPEGYVLTNNHVVERMDDIEVVLSDGRRTKAEVIGTDPEADLAVLR
IKLDKLPSVSFGDSDALQVGDVVLAIGNPFGVGQTVTSGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALIDAAGNL
MGINTAIYSRSGGSLGIGFAIPVSTARQVMEGLIRDGQVTRGWIGVEPRDLTPEIAETFNLKVSQGVLITGVLQGGPASD
GGLRPGDVVVKVADSPVGNTSQLLNVVASLKPRSKARLVVQRGDSEVTLDVIVAQRPKAPRQQREP
>Mature_386_residues
MRKTWLIFSQAVTVALAMWFVVATLKPEWVQNRPLSTAVGSSSNPAPQITLAPAAAGGSSYAAAAKRAAPAVVSVITSKT
PTARDPRAADPWFRYFFGDPDSQAQSGVGSGVIVSPEGYVLTNNHVVERMDDIEVVLSDGRRTKAEVIGTDPEADLAVLR
IKLDKLPSVSFGDSDALQVGDVVLAIGNPFGVGQTVTSGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALIDAAGNL
MGINTAIYSRSGGSLGIGFAIPVSTARQVMEGLIRDGQVTRGWIGVEPRDLTPEIAETFNLKVSQGVLITGVLQGGPASD
GGLRPGDVVVKVADSPVGNTSQLLNVVASLKPRSKARLVVQRGDSEVTLDVIVAQRPKAPRQQREP

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=327, Percent_Identity=33.6391437308869, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI7019477, Length=281, Percent_Identity=37.0106761565836, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4506141, Length=279, Percent_Identity=34.7670250896057, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI22129776, Length=282, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI1789629, Length=379, Percent_Identity=40.8970976253298, Blast_Score=257, Evalue=7e-70,
Organism=Escherichia coli, GI1786356, Length=344, Percent_Identity=39.5348837209302, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1789630, Length=378, Percent_Identity=36.7724867724868, Blast_Score=225, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24646839, Length=304, Percent_Identity=32.8947368421053, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40325; Mature: 40325

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTWLIFSQAVTVALAMWFVVATLKPEWVQNRPLSTAVGSSSNPAPQITLAPAAAGGSS
CCCEEEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHCCCCCCCCCEEEEECCCCCCCH
YAAAAKRAAPAVVSVITSKTPTARDPRAADPWFRYFFGDPDSQAQSGVGSGVIVSPEGYV
HHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCCCHHHCCCCCCEEECCCCEE
LTNNHVVERMDDIEVVLSDGRRTKAEVIGTDPEADLAVLRIKLDKLPSVSFGDSDALQVG
EECCHHHHHHHHHHEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEC
DVVLAIGNPFGVGQTVTSGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALIDAAGNL
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCE
MGINTAIYSRSGGSLGIGFAIPVSTARQVMEGLIRDGQVTRGWIGVEPRDLTPEIAETFN
EEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCEEECEECCCCCCCCHHHHHHCC
LKVSQGVLITGVLQGGPASDGGLRPGDVVVKVADSPVGNTSQLLNVVASLKPRSKARLVV
CEEECCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEE
QRGDSEVTLDVIVAQRPKAPRQQREP
EECCCEEEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MRKTWLIFSQAVTVALAMWFVVATLKPEWVQNRPLSTAVGSSSNPAPQITLAPAAAGGSS
CCCEEEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHCCCCCCCCCEEEEECCCCCCCH
YAAAAKRAAPAVVSVITSKTPTARDPRAADPWFRYFFGDPDSQAQSGVGSGVIVSPEGYV
HHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCCCHHHCCCCCCEEECCCCEE
LTNNHVVERMDDIEVVLSDGRRTKAEVIGTDPEADLAVLRIKLDKLPSVSFGDSDALQVG
EECCHHHHHHHHHHEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEC
DVVLAIGNPFGVGQTVTSGIVSALGRNQLGINTFENFIQTDAAINPGNSGGALIDAAGNL
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCE
MGINTAIYSRSGGSLGIGFAIPVSTARQVMEGLIRDGQVTRGWIGVEPRDLTPEIAETFN
EEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCEEECEECCCCCCCCHHHHHHCC
LKVSQGVLITGVLQGGPASDGGLRPGDVVVKVADSPVGNTSQLLNVVASLKPRSKARLVV
CEEECCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEE
QRGDSEVTLDVIVAQRPKAPRQQREP
EECCCEEEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]