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The map label for this gene is mop [H]

Identifier: 124265991

GI number: 124265991

Start: 833273

End: 835765

Strand: Reverse

Name: mop [H]

Synonym: Mpe_A0798

Alternate gene names: 124265991

Gene position: 835765-833273 (Counterclockwise)

Preceding gene: 124265992

Following gene: 124265990

Centisome position: 20.67

GC content: 72.0

Gene sequence:

>2493_bases
TTGGCGGGGGTACCCGATGCGCGTTGCCACTCACCCACCCACCCACGGGGCCCCACCCTCCACCTCGCCGCAGCACCGCC
CCGAAGACCCTGGCATGAACAGGAACAGGAGACTCCGGTGAACAAGCAGGCCGACGCCTTCCTCGTCGACAGCAGCACCC
AGCCCCCCTCGGAGCAGACCGCCCCCGAGGCCGGCCGCGCGCGACCCCATGAGTCGGCGCACCTGCACGTGGCCGGTGCG
GCACCCTACATCGACGACCTGCCCGAGCTGGTCGGCACGCTGCACGCGGCACTGGGCCTGTCGCCGGTGGCGCACGGCGT
GCTGAAGGCGATCGACGTCGAGCGGCTGAAGGCCCTGCCCGGCGTCGTGGCGGTGCTGACCGCGGCTGACATCCCCGGGC
CCAACGACTGCGGCCCCATCGTGCACGACGAGCCCATCCTCGCCACCGGCCACGTGCACTACCTCGGCCAACCGGTGTTC
GCGGTGATCGCCACCGACCGCGAGCGGGCGCGCCGCGCTGCCGCCCAGGCGAAGGCGGTGCTCTCGATCGACCCGCTGCC
ACCGGTGCTGAGTGCGCTGGAGGCACACGCGAAGCGGCAGTACGTGCTGCCCGACATGCACCTGGTGCGCGAGTCGGCGC
CCGGCGCGCTGCACGCCGCGCTGGCCGCCGCACCGCACCGCCTGCAGGGCACGCTGAGCGTCGGCGGCCAGGAGCAGTTC
TACCTGGAAGGCCAGATCTCCTACGCCTGCCCGACCGAGAACGCCGGGCTCAAGGTCCATTGTTCGACCCAGCACCCGAG
CGAGATGCAGCATCTGGTGGCGCATGCGCTGGGCTGGCGCTCCAACCAGGTGCAGGTCGAATGCCGGCGCATGGGCGGTG
GCTTCGGCGGCAAGGAGTCGCAGTCGGCGGTGTTCGCCTGCGTCGCCTCGGTGGCCGCGGTGAAGCTGCAGCGGCCGGTG
AAGCTGCGCGTGGACCGTGACGACGACTTCCTCGTCACCGGCCGCCGGCACGGCTTCGAGTACGCCTGGGAGGTCGGCTG
CGACGACGCCGGCCGCGTGCTGGCGGCCGAGGTGACGATGGTGTCGAACGCTGGCTGGAGCGCCGACCTGTCGGGCCCGG
TGATGACGCGCGCGCTCTGCCACTTCGACAACGCCTACTGGCTGCCCGAGGTGGCGATGCACGGCCACAGCGCGCGCACC
AACACCCAGAGCAACACCGCCTTCCGCGGCTTCGGCGGGCCGCAGGGCGCGATCGCGATCGAGGTCATCCTCGACTCGGT
GGCGCGCCGGCTCGGCCTGGACCCGCTGGCGGTTCGGCGCGCCAACTTCTACGGCACGACCTCGAACAACGTCACGCCCT
ACGGCCAGCAGGTCGACGACAACGTGATCGCGCCGCTGGTCGACACGCTGGCCGCGAGCAGCGACTACGCCGCGCGCCGC
GCGGCCGTCGCCGCCTACAACGCCGCCAGCCCGGTGCTGAAGAAGGGCCTGGCGCTGACACCGGTGAAGTTCGGCATCTC
GTTCAACGTGGCGCACTTCAACCAGGCCGGCGCGCTGGTGCACATCTACACCGACGGCTCGGTGCTGGTGAACCACGGCG
GCACCGAGATGGGCCAGGGCCTGAACACCAAGGTGGCGCAGGTGGTGGCGCACGAGCTCGGCATCGCCTTCGAGCGCGTG
CGCGTGAGCGCCACCGACACCCACAAGGTCGCCAACACCTCGGCCACCGCGGCCTCGACCGGCAGCGACCTGAACGGCAA
GGCCGCGCAGGACGCGGCCCGCCAGCTGCGCGAGCGGCTCGCCGCGCTGGCGGCCTCGATGCATGGCGGCATGCCGGAGG
CGGTGCGCTTCGCCGACGACCGCGTGCACGTCAATGGCGCGAACCTCGACTTCGACGCGCTGGTGGCGCAGGCCTACGCC
GCGCGCGTGCAGCTGTGGAGCGACGGCTTCTACGCCACGCCCGGCCTGCACTGGAACCGCGAGACGCTGCAGGGCCGACC
GTTCTACTACTTCGCCTACGGCGCGGCGGTGGCCGAGGTGGTCGTCGATACGCTGAGCGGCGAGCACCGCCTGCTGCGCG
CCGACCTGCTGCACGACGTGGGCCGCTCGCTGAATCCGGCGGTCGACATCGGCCAGGTGGAGGGCGCGTTCATCCAGGGC
ATGGGCTGGCTGACCTCGGAGGAGCTGGTCTGGCACCCCAAGACCGGCCTGCTGATGACGCACGCGCCCAGCACCTACAA
GATCCCGACCGCGAACGACTGCCCGCCGGTCTTCCGCACCGCGCTGTTCGAGAACAACGACAACGTCGAGGACAGCATCC
ACCGCAGCAAGGCGGTCGGCGAGCCGCCGCTGCTGCTGCCGTTCTCGGTGTTCCTGGCGATCCGCGACGCGGTCTCGGCG
GTCGGCGGCCACCGCGTCGACCCGCCGCTGCGCGCGCCGGCCACGCCCGAGGCGGTGCTCGACGCGATCGACGCGGTGCG
TGCGGCACGCTGA

Upstream 100 bases:

>100_bases
TTGAGTCGGACCGTACTGCGTCCATGAGCCTTTTTTCGATGCCTGATCCTGTCGTTCCTGTCGGGCGCGCGCGGGGCCAT
GGGCGGGTGAGCGTCATCGC

Downstream 100 bases:

>100_bases
AGCCACCATGACCCTGCGCACCCACGCCCTCCGCTGGCTCGACGCATCCCGCCCGGCGATCGTCGTCGAGGTGGCTGCCA
CGCGCGGCTCGGTGCCCCGC

Product: xanthine oxidase

Products: NA

Alternate protein names: Molybdenum iron sulfur protein [H]

Number of amino acids: Translated: 830; Mature: 829

Protein sequence:

>830_residues
MAGVPDARCHSPTHPRGPTLHLAAAPPRRPWHEQEQETPVNKQADAFLVDSSTQPPSEQTAPEAGRARPHESAHLHVAGA
APYIDDLPELVGTLHAALGLSPVAHGVLKAIDVERLKALPGVVAVLTAADIPGPNDCGPIVHDEPILATGHVHYLGQPVF
AVIATDRERARRAAAQAKAVLSIDPLPPVLSALEAHAKRQYVLPDMHLVRESAPGALHAALAAAPHRLQGTLSVGGQEQF
YLEGQISYACPTENAGLKVHCSTQHPSEMQHLVAHALGWRSNQVQVECRRMGGGFGGKESQSAVFACVASVAAVKLQRPV
KLRVDRDDDFLVTGRRHGFEYAWEVGCDDAGRVLAAEVTMVSNAGWSADLSGPVMTRALCHFDNAYWLPEVAMHGHSART
NTQSNTAFRGFGGPQGAIAIEVILDSVARRLGLDPLAVRRANFYGTTSNNVTPYGQQVDDNVIAPLVDTLAASSDYAARR
AAVAAYNAASPVLKKGLALTPVKFGISFNVAHFNQAGALVHIYTDGSVLVNHGGTEMGQGLNTKVAQVVAHELGIAFERV
RVSATDTHKVANTSATAASTGSDLNGKAAQDAARQLRERLAALAASMHGGMPEAVRFADDRVHVNGANLDFDALVAQAYA
ARVQLWSDGFYATPGLHWNRETLQGRPFYYFAYGAAVAEVVVDTLSGEHRLLRADLLHDVGRSLNPAVDIGQVEGAFIQG
MGWLTSEELVWHPKTGLLMTHAPSTYKIPTANDCPPVFRTALFENNDNVEDSIHRSKAVGEPPLLLPFSVFLAIRDAVSA
VGGHRVDPPLRAPATPEAVLDAIDAVRAAR

Sequences:

>Translated_830_residues
MAGVPDARCHSPTHPRGPTLHLAAAPPRRPWHEQEQETPVNKQADAFLVDSSTQPPSEQTAPEAGRARPHESAHLHVAGA
APYIDDLPELVGTLHAALGLSPVAHGVLKAIDVERLKALPGVVAVLTAADIPGPNDCGPIVHDEPILATGHVHYLGQPVF
AVIATDRERARRAAAQAKAVLSIDPLPPVLSALEAHAKRQYVLPDMHLVRESAPGALHAALAAAPHRLQGTLSVGGQEQF
YLEGQISYACPTENAGLKVHCSTQHPSEMQHLVAHALGWRSNQVQVECRRMGGGFGGKESQSAVFACVASVAAVKLQRPV
KLRVDRDDDFLVTGRRHGFEYAWEVGCDDAGRVLAAEVTMVSNAGWSADLSGPVMTRALCHFDNAYWLPEVAMHGHSART
NTQSNTAFRGFGGPQGAIAIEVILDSVARRLGLDPLAVRRANFYGTTSNNVTPYGQQVDDNVIAPLVDTLAASSDYAARR
AAVAAYNAASPVLKKGLALTPVKFGISFNVAHFNQAGALVHIYTDGSVLVNHGGTEMGQGLNTKVAQVVAHELGIAFERV
RVSATDTHKVANTSATAASTGSDLNGKAAQDAARQLRERLAALAASMHGGMPEAVRFADDRVHVNGANLDFDALVAQAYA
ARVQLWSDGFYATPGLHWNRETLQGRPFYYFAYGAAVAEVVVDTLSGEHRLLRADLLHDVGRSLNPAVDIGQVEGAFIQG
MGWLTSEELVWHPKTGLLMTHAPSTYKIPTANDCPPVFRTALFENNDNVEDSIHRSKAVGEPPLLLPFSVFLAIRDAVSA
VGGHRVDPPLRAPATPEAVLDAIDAVRAAR
>Mature_829_residues
AGVPDARCHSPTHPRGPTLHLAAAPPRRPWHEQEQETPVNKQADAFLVDSSTQPPSEQTAPEAGRARPHESAHLHVAGAA
PYIDDLPELVGTLHAALGLSPVAHGVLKAIDVERLKALPGVVAVLTAADIPGPNDCGPIVHDEPILATGHVHYLGQPVFA
VIATDRERARRAAAQAKAVLSIDPLPPVLSALEAHAKRQYVLPDMHLVRESAPGALHAALAAAPHRLQGTLSVGGQEQFY
LEGQISYACPTENAGLKVHCSTQHPSEMQHLVAHALGWRSNQVQVECRRMGGGFGGKESQSAVFACVASVAAVKLQRPVK
LRVDRDDDFLVTGRRHGFEYAWEVGCDDAGRVLAAEVTMVSNAGWSADLSGPVMTRALCHFDNAYWLPEVAMHGHSARTN
TQSNTAFRGFGGPQGAIAIEVILDSVARRLGLDPLAVRRANFYGTTSNNVTPYGQQVDDNVIAPLVDTLAASSDYAARRA
AVAAYNAASPVLKKGLALTPVKFGISFNVAHFNQAGALVHIYTDGSVLVNHGGTEMGQGLNTKVAQVVAHELGIAFERVR
VSATDTHKVANTSATAASTGSDLNGKAAQDAARQLRERLAALAASMHGGMPEAVRFADDRVHVNGANLDFDALVAQAYAA
RVQLWSDGFYATPGLHWNRETLQGRPFYYFAYGAAVAEVVVDTLSGEHRLLRADLLHDVGRSLNPAVDIGQVEGAFIQGM
GWLTSEELVWHPKTGLLMTHAPSTYKIPTANDCPPVFRTALFENNDNVEDSIHRSKAVGEPPLLLPFSVFLAIRDAVSAV
GGHRVDPPLRAPATPEAVLDAIDAVRAAR

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=775, Percent_Identity=40.9032258064516, Blast_Score=559, Evalue=1e-159,
Organism=Homo sapiens, GI71773480, Length=755, Percent_Identity=38.1456953642384, Blast_Score=461, Evalue=1e-129,
Organism=Escherichia coli, GI1789230, Length=768, Percent_Identity=27.34375, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1789246, Length=752, Percent_Identity=27.1276595744681, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1786478, Length=779, Percent_Identity=25.2888318356868, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=764, Percent_Identity=40.3141361256544, Blast_Score=523, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI32566215, Length=731, Percent_Identity=30.3693570451436, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17539860, Length=743, Percent_Identity=31.0901749663526, Blast_Score=321, Evalue=1e-87,
Organism=Drosophila melanogaster, GI17737937, Length=783, Percent_Identity=41.1238825031928, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI24647193, Length=775, Percent_Identity=31.2258064516129, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=31.7169069462647, Blast_Score=321, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24647201, Length=784, Percent_Identity=29.9744897959184, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24647195, Length=760, Percent_Identity=28.0263157894737, Blast_Score=273, Evalue=5e-73,
Organism=Drosophila melanogaster, GI24647197, Length=760, Percent_Identity=28.0263157894737, Blast_Score=272, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2; PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.7 [H]

Molecular weight: Translated: 88457; Mature: 88325

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVPDARCHSPTHPRGPTLHLAAAPPRRPWHEQEQETPVNKQADAFLVDSSTQPPSEQT
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCC
APEAGRARPHESAHLHVAGAAPYIDDLPELVGTLHAALGLSPVAHGVLKAIDVERLKALP
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GVVAVLTAADIPGPNDCGPIVHDEPILATGHVHYLGQPVFAVIATDRERARRAAAQAKAV
CHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHCCCEEEEEECCHHHHHHHHHHHCEE
LSIDPLPPVLSALEAHAKRQYVLPDMHLVRESAPGALHAALAAAPHRLQGTLSVGGQEQF
EEECCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCHHEEEEEECCCCEEE
YLEGQISYACPTENAGLKVHCSTQHPSEMQHLVAHALGWRSNQVQVECRRMGGGFGGKES
EEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
QSAVFACVASVAAVKLQRPVKLRVDRDDDFLVTGRRHGFEYAWEVGCDDAGRVLAAEVTM
HHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEEE
VSNAGWSADLSGPVMTRALCHFDNAYWLPEVAMHGHSARTNTQSNTAFRGFGGPQGAIAI
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCHH
EVILDSVARRLGLDPLAVRRANFYGTTSNNVTPYGQQVDDNVIAPLVDTLAASSDYAARR
HHHHHHHHHHHCCCHHHHHHCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
AAVAAYNAASPVLKKGLALTPVKFGISFNVAHFNQAGALVHIYTDGSVLVNHGGTEMGQG
HHHHHHCCCCHHHHCCCEECEEEECEEEEEEEECCCCCEEEEEECCEEEEECCCHHHCCC
LNTKVAQVVAHELGIAFERVRVSATDTHKVANTSATAASTGSDLNGKAAQDAARQLRERL
CCHHHHHHHHHHHHHEEEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALAASMHGGMPEAVRFADDRVHVNGANLDFDALVAQAYAARVQLWSDGFYATPGLHWNR
HHHHHHHCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCH
ETLQGRPFYYFAYGAAVAEVVVDTLSGEHRLLRADLLHDVGRSLNPAVDIGQVEGAFIQG
HHCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHC
MGWLTSEELVWHPKTGLLMTHAPSTYKIPTANDCPPVFRTALFENNDNVEDSIHRSKAVG
CCCCCCCCEEEECCCCEEEEECCCCEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
EPPLLLPFSVFLAIRDAVSAVGGHRVDPPLRAPATPEAVLDAIDAVRAAR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGVPDARCHSPTHPRGPTLHLAAAPPRRPWHEQEQETPVNKQADAFLVDSSTQPPSEQT
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCC
APEAGRARPHESAHLHVAGAAPYIDDLPELVGTLHAALGLSPVAHGVLKAIDVERLKALP
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GVVAVLTAADIPGPNDCGPIVHDEPILATGHVHYLGQPVFAVIATDRERARRAAAQAKAV
CHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHCCCEEEEEECCHHHHHHHHHHHCEE
LSIDPLPPVLSALEAHAKRQYVLPDMHLVRESAPGALHAALAAAPHRLQGTLSVGGQEQF
EEECCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCHHEEEEEECCCCEEE
YLEGQISYACPTENAGLKVHCSTQHPSEMQHLVAHALGWRSNQVQVECRRMGGGFGGKES
EEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
QSAVFACVASVAAVKLQRPVKLRVDRDDDFLVTGRRHGFEYAWEVGCDDAGRVLAAEVTM
HHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEEE
VSNAGWSADLSGPVMTRALCHFDNAYWLPEVAMHGHSARTNTQSNTAFRGFGGPQGAIAI
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCHH
EVILDSVARRLGLDPLAVRRANFYGTTSNNVTPYGQQVDDNVIAPLVDTLAASSDYAARR
HHHHHHHHHHHCCCHHHHHHCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
AAVAAYNAASPVLKKGLALTPVKFGISFNVAHFNQAGALVHIYTDGSVLVNHGGTEMGQG
HHHHHHCCCCHHHHCCCEECEEEECEEEEEEEECCCCCEEEEEECCEEEEECCCHHHCCC
LNTKVAQVVAHELGIAFERVRVSATDTHKVANTSATAASTGSDLNGKAAQDAARQLRERL
CCHHHHHHHHHHHHHEEEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALAASMHGGMPEAVRFADDRVHVNGANLDFDALVAQAYAARVQLWSDGFYATPGLHWNR
HHHHHHHCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCH
ETLQGRPFYYFAYGAAVAEVVVDTLSGEHRLLRADLLHDVGRSLNPAVDIGQVEGAFIQG
HHCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHC
MGWLTSEELVWHPKTGLLMTHAPSTYKIPTANDCPPVFRTALFENNDNVEDSIHRSKAVG
CCCCCCCCEEEECCCCEEEEECCCCEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
EPPLLLPFSVFLAIRDAVSAVGGHRVDPPLRAPATPEAVLDAIDAVRAAR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8143744; 7502041; 8799115; 11713686 [H]