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The map label for this gene is ygfU [H]

Identifier: 124265974

GI number: 124265974

Start: 815700

End: 817301

Strand: Direct

Name: ygfU [H]

Synonym: Mpe_A0781

Alternate gene names: 124265974

Gene position: 815700-817301 (Clockwise)

Preceding gene: 124265973

Following gene: 124265975

Centisome position: 20.17

GC content: 70.35

Gene sequence:

>1602_bases
ATGGCTTCGGGCACACCCCCCACCGTCCACCCGGTCGACGAGAAGCTGCCCGCCGGACGGCTGGCGACGCTGGGCCTGCA
GCATGTGCTGGTGATGTACGCCGGCGCCGTGGCCGTGCCGCTGATCGTCGGCCGCGCGCTCAAGCTCAGCCCCGAGCAGG
TGGCGATGCTGATCTCGGCCGACCTGTTCTGCTGCGGCATCGCCACGCTGATCCAGTCGCTGGGCGCGACGCGCTGGTTC
GGCGTGAAGCTGCCGGTCATGATGGGCGTGACCTTCGCCGCGGTCGGCCCGATGGTGGCGATGGCCGGACCCGGCGGCAC
CGAAGCGGCGCGCGCCATCTTCGGCGCCATCATCGGTGCGGGCCTGCTGGCGATCTTCATCGCGCCGGTGATGGGGCGCT
TGCTTCGCTTCTTTCCGCCGGTGGTGACCGGCACCATCATCGCGGTGATCGGCATCAGCCTGATGCGCGTGGGCATCGGC
TGGGCGATGGGCGGTCCGGCCCACCTGGCGCAGTTCACCGACGTGCCCCGGCTGGTGGTGATGGTCGACCAGGCCAAGGC
CGAGGCGCTGGCCGGCAATGCGGCGGTGGCCGCACTGTCGGCCGGCTCGGCTCCGGCGGCGGGTGTCGCGACGCAGGCCG
CTGCCGCCGCCACGGCTTCGGCCAATGCCGGCACGAATGCGGGCGCCGCCCCCGTGCCGGTGGTCACCCGGCTGCCGGGG
CCGGTGCCGCAGAAGGACAACCCGGCCTACGGCGCGCTCGACAACATGGCCGTCGCGGCCTTCGTGCTGGGGGTGATCCT
GCTGATCTCCAAGTACGGCCGGGGCTTCGTCGCCAACATCTCGGTGCTGCTGGGCATCGTGGCGGGCTGCGTGGTGGCCG
TGGCGATGGGCAAGATGGGGTTCGACAAGGTGGCCAAGGCGCACTGGTTCGACGTGGTCACGCCGTTCGCCTTCGGCCCG
CCGGTGTTCGACCCGGTGCTGATCGCGACGATGACGCTGGTGATGGTGGTCGTGATGATCGAGTCGACCGGCATGTTCCT
CGCGCTGTCCGACCTGACCGGCAAGCCGATCGACCAGCGCGAGCTGACGGCCGGGTTGCGCACCGACGGGCTGGGCACGT
TGATCGGCGGCATGTTCAACACCTTCCCCTACACCAGCTTCTCGCAGAACGTGGGGCTGGTGGGTGTGACCGGGGTGCGC
AGCCGCTACGTGTGCGTGGCGGCGGGGCTGATCATGATCGTGCTGGGCCTGCTGCCGAAGATGGCGGCGCTGGTCGAGTC
GGTGCCGACCTTCGTGCTGGGCGGCGCCGGGCTGGTGATGTTCGGCATGGTGGCCGCCACCGGCATCCGCATCCTCGCCG
CGGTGGACTACAAGACTCATCGCCACAACCTCTACATCGTGGCCATCTCCATCGGCTTCGGCATGCTGCCGCTGGTGGCG
CCGCGCTGGACGCAGCAGATGCACCACGGCCTGCACCCGCTGCTGGAGTCCGGCATCCTGCTGGCGGCGCTGAGCGCGGT
GCTGCTGAACCTGTACTTCAACGGTGCCAAGGGCGGGGCGGCGGATGCGGTCGAGGCGGCGAAGCTGGCCGAGGCGCATT
GA

Upstream 100 bases:

>100_bases
GCTGCTGGGTCGTTGGTACGAGGCCGGCGCGCCGCCCCGTTAGCGGGCAAGGCCTGGGTACGGGCCTTGCAAGGACCCGA
GGGCATTCGAGGAGAACGCC

Downstream 100 bases:

>100_bases
TTTTCTGGGGGGTGGTGTGTGGTGCGGCAGGCGGTGTGTGCCGAGGGCTCGGGCGGGGGCGGTCGGCGCTGCGCGCCGAC
GCCACTGCGGTGCTCGCGGC

Product: putative permease transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MASGTPPTVHPVDEKLPAGRLATLGLQHVLVMYAGAVAVPLIVGRALKLSPEQVAMLISADLFCCGIATLIQSLGATRWF
GVKLPVMMGVTFAAVGPMVAMAGPGGTEAARAIFGAIIGAGLLAIFIAPVMGRLLRFFPPVVTGTIIAVIGISLMRVGIG
WAMGGPAHLAQFTDVPRLVVMVDQAKAEALAGNAAVAALSAGSAPAAGVATQAAAAATASANAGTNAGAAPVPVVTRLPG
PVPQKDNPAYGALDNMAVAAFVLGVILLISKYGRGFVANISVLLGIVAGCVVAVAMGKMGFDKVAKAHWFDVVTPFAFGP
PVFDPVLIATMTLVMVVVMIESTGMFLALSDLTGKPIDQRELTAGLRTDGLGTLIGGMFNTFPYTSFSQNVGLVGVTGVR
SRYVCVAAGLIMIVLGLLPKMAALVESVPTFVLGGAGLVMFGMVAATGIRILAAVDYKTHRHNLYIVAISIGFGMLPLVA
PRWTQQMHHGLHPLLESGILLAALSAVLLNLYFNGAKGGAADAVEAAKLAEAH

Sequences:

>Translated_533_residues
MASGTPPTVHPVDEKLPAGRLATLGLQHVLVMYAGAVAVPLIVGRALKLSPEQVAMLISADLFCCGIATLIQSLGATRWF
GVKLPVMMGVTFAAVGPMVAMAGPGGTEAARAIFGAIIGAGLLAIFIAPVMGRLLRFFPPVVTGTIIAVIGISLMRVGIG
WAMGGPAHLAQFTDVPRLVVMVDQAKAEALAGNAAVAALSAGSAPAAGVATQAAAAATASANAGTNAGAAPVPVVTRLPG
PVPQKDNPAYGALDNMAVAAFVLGVILLISKYGRGFVANISVLLGIVAGCVVAVAMGKMGFDKVAKAHWFDVVTPFAFGP
PVFDPVLIATMTLVMVVVMIESTGMFLALSDLTGKPIDQRELTAGLRTDGLGTLIGGMFNTFPYTSFSQNVGLVGVTGVR
SRYVCVAAGLIMIVLGLLPKMAALVESVPTFVLGGAGLVMFGMVAATGIRILAAVDYKTHRHNLYIVAISIGFGMLPLVA
PRWTQQMHHGLHPLLESGILLAALSAVLLNLYFNGAKGGAADAVEAAKLAEAH
>Mature_532_residues
ASGTPPTVHPVDEKLPAGRLATLGLQHVLVMYAGAVAVPLIVGRALKLSPEQVAMLISADLFCCGIATLIQSLGATRWFG
VKLPVMMGVTFAAVGPMVAMAGPGGTEAARAIFGAIIGAGLLAIFIAPVMGRLLRFFPPVVTGTIIAVIGISLMRVGIGW
AMGGPAHLAQFTDVPRLVVMVDQAKAEALAGNAAVAALSAGSAPAAGVATQAAAAATASANAGTNAGAAPVPVVTRLPGP
VPQKDNPAYGALDNMAVAAFVLGVILLISKYGRGFVANISVLLGIVAGCVVAVAMGKMGFDKVAKAHWFDVVTPFAFGPP
VFDPVLIATMTLVMVVVMIESTGMFLALSDLTGKPIDQRELTAGLRTDGLGTLIGGMFNTFPYTSFSQNVGLVGVTGVRS
RYVCVAAGLIMIVLGLLPKMAALVESVPTFVLGGAGLVMFGMVAATGIRILAAVDYKTHRHNLYIVAISIGFGMLPLVAP
RWTQQMHHGLHPLLESGILLAALSAVLLNLYFNGAKGGAADAVEAAKLAEAH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=182, Percent_Identity=34.6153846153846, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI40316845, Length=182, Percent_Identity=34.6153846153846, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI44680143, Length=176, Percent_Identity=34.0909090909091, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI44680145, Length=176, Percent_Identity=34.0909090909091, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082181, Length=283, Percent_Identity=53.7102473498233, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1790087, Length=285, Percent_Identity=33.6842105263158, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788843, Length=203, Percent_Identity=31.5270935960591, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87081818, Length=216, Percent_Identity=31.0185185185185, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082178, Length=275, Percent_Identity=27.6363636363636, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17558856, Length=224, Percent_Identity=29.4642857142857, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356175, Length=187, Percent_Identity=34.7593582887701, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 54380; Mature: 54248

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGTPPTVHPVDEKLPAGRLATLGLQHVLVMYAGAVAVPLIVGRALKLSPEQVAMLISA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLFCCGIATLIQSLGATRWFGVKLPVMMGVTFAAVGPMVAMAGPGGTEAARAIFGAIIGA
HHHHHHHHHHHHHCCCCEEECEEHHHHHHHHHHHHHCHHEECCCCCHHHHHHHHHHHHHH
GLLAIFIAPVMGRLLRFFPPVVTGTIIAVIGISLMRVGIGWAMGGPAHLAQFTDVPRLVV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
MVDQAKAEALAGNAAVAALSAGSAPAAGVATQAAAAATASANAGTNAGAAPVPVVTRLPG
EECHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PVPQKDNPAYGALDNMAVAAFVLGVILLISKYGRGFVANISVLLGIVAGCVVAVAMGKMG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
FDKVAKAHWFDVVTPFAFGPPVFDPVLIATMTLVMVVVMIESTGMFLALSDLTGKPIDQR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
ELTAGLRTDGLGTLIGGMFNTFPYTSFSQNVGLVGVTGVRSRYVCVAAGLIMIVLGLLPK
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
MAALVESVPTFVLGGAGLVMFGMVAATGIRILAAVDYKTHRHNLYIVAISIGFGMLPLVA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCEECCCEEEEEEEECCCCHHHHCC
PRWTQQMHHGLHPLLESGILLAALSAVLLNLYFNGAKGGAADAVEAAKLAEAH
CHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ASGTPPTVHPVDEKLPAGRLATLGLQHVLVMYAGAVAVPLIVGRALKLSPEQVAMLISA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLFCCGIATLIQSLGATRWFGVKLPVMMGVTFAAVGPMVAMAGPGGTEAARAIFGAIIGA
HHHHHHHHHHHHHCCCCEEECEEHHHHHHHHHHHHHCHHEECCCCCHHHHHHHHHHHHHH
GLLAIFIAPVMGRLLRFFPPVVTGTIIAVIGISLMRVGIGWAMGGPAHLAQFTDVPRLVV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
MVDQAKAEALAGNAAVAALSAGSAPAAGVATQAAAAATASANAGTNAGAAPVPVVTRLPG
EECHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PVPQKDNPAYGALDNMAVAAFVLGVILLISKYGRGFVANISVLLGIVAGCVVAVAMGKMG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
FDKVAKAHWFDVVTPFAFGPPVFDPVLIATMTLVMVVVMIESTGMFLALSDLTGKPIDQR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
ELTAGLRTDGLGTLIGGMFNTFPYTSFSQNVGLVGVTGVRSRYVCVAAGLIMIVLGLLPK
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
MAALVESVPTFVLGGAGLVMFGMVAATGIRILAAVDYKTHRHNLYIVAISIGFGMLPLVA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCEECCCEEEEEEEECCCCHHHHCC
PRWTQQMHHGLHPLLESGILLAALSAVLLNLYFNGAKGGAADAVEAAKLAEAH
CHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]