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The map label for this gene is amaB [H]

Identifier: 124265969

GI number: 124265969

Start: 810353

End: 812152

Strand: Reverse

Name: amaB [H]

Synonym: Mpe_A0776

Alternate gene names: 124265969

Gene position: 812152-810353 (Counterclockwise)

Preceding gene: 124265970

Following gene: 124265968

Centisome position: 20.08

GC content: 73.67

Gene sequence:

>1800_bases
GTGACCACCGCTGCCCCCACCCCGCTGACGCTCGCCTGGCTCAACGATGCGCCGGCCGAGGCGGCGCTGGCCGCGCTCGA
CGGGCTCTACGAGCACTCGCCGTGGATTGCCGAGGCGGCACTGCGCCAGCGGCCATTCACCAGCCTGGCGCAGCTCAAGC
ATGCGATGGTGCGCGTGGTGCGCGAGGCCGGGCGCGAGGCCCAGCTCGCGCTGGTGCGCGCCCACCCCGAGCTGGCGGGC
AAGGCCGCGGTGGCCGGCACGCTGACCGCCGAATCGACCGGCGAGCAGGCGCGCGCCGGCCTGAACCACTGCTCCCCGGA
GGAGTTCGCGCTGGTGCAGCGGCTCAACGCCGAATACGGCGCGCGCTTCGGCTGGCCCTTCGTGCTGGCGGTGCGCGGCC
CGCGCGGCGAGGGCCTGCACCGGCGCGAGATCCTCGCGACGCTGCAGCGCCGGCTGCAGGGCCACCCCGAGATCGAGCTG
GTCGAGTGCCTGCGCAACATCGACCGCATCGCCGAGATCCGCCTGAACGACAAGTTCGGCGCCGCGCCGATCCTGGGCAA
CCCGGTGTGGGACTGGGCCGAGCAGCTGGCCGTGCACACCGACCCGGGCTATGGCGAACGCGGCGAGCTCACCGTCACTT
ACCTGACCGACGCGCACCGTGCCTGCGCCGCGCAGCTGCAGGCCTGGATGCGCGACTGCGGCTTCGACGAGGTGCGCCTC
GATGCGGTCGGCAACGTGGTGGGCCTCTACCTCGGCAGCGATCCGTCGGCGCGGCGCCTGCTCACCGGCAGCCACTACGA
CACCGTGCGCAACGGCGGCAAGTACGACGGCCGGCTCGGCATCCTGGTGCCGATGGCCTGCGTGCGCGAGCTGCACCGCG
CCGGCCGGCGCCTGCCCTTCGGACTCGAGGTGGTCGGCTTCGCCGAAGAGGAGGGTCAGCGCTACAAGGCCACCTTCCTC
GGCTCCGGCGCGCTGACCGGCCACTTCGAGCCCGCCTGGCTGGACCAGCAGGACGCCGACGGCGTGACGATGCGCACCGC
GATGCTGGCCGCCGGCCTGCCGGCCACGCTGGAGGCGATCGCGGCCGAGGCGCGCGATGCGGCGCGCTACCTCGGCTTCG
TCGAGGTCCACATCGAGCAGGGCCCGGTGCTCGCCGAGCTGGACCTGCCGCTGGGCGTGGTGAGCTCCATCAACGGCAGC
GTGCGCTACCTCGGCGAGGTGGTCGGCGTCGCCAGCCACGCCGGCACCACGCCGATGGACCGCCGGCGGGATGCCGCCAC
CGCGGTCGCCGAGTTGGCGCTCTACGTCGAGCAGCGCGCCGCTGCGGCGCCGCACCTGGTCGGCACCGTCGGCATGCTGG
AGGTGCCCAACGGCTCGATCAACGTCGTGCCGGGCCGTTGCCGTTTCAGCATCGACATCCGCTCCACCACCAACGAAGTG
CGCGACGCGATGGCGGCCGACGTGCGCGAGCGGCTGGCCGCGATCTGCGAGCGCCGCGGCCTCGCCTACCGCCTCGAGGA
AACCGTGCGCGCCGCGGCCGCCCCCAGCGACGCCGCCTGGCAGCGCCGCTGGGAGGCCGCCGTCGCCGCCACCGGCCTGC
CGGTGCACCGCCTGCCCAGCGGCGCCGGCCACGACGCGATGAAGCTGCACGAGGTGATGCCGCAGGCCATGCTGTTCGTG
CGTGGCGAGAACGCCGGCATCAGCCACAACCCGCTCGAATCCACCACGGCCGACGACATGCAGCTTGCGGTCGAGGCCTT
CACGCACCTGCTCGACGCCCTGAGCCACGACACGCCATGA

Upstream 100 bases:

>100_bases
TCCTCGACCACATCGAGGCGCACGACCGCGTCTGGGTGTGCCGGCGCATCGACATCGCGCGGCACTGGCAGGCCACCCAC
CCCTGCGCGAAGGCCTCCAC

Downstream 100 bases:

>100_bases
GCACCCCCCACGACCGACTCGACGCCTGGATCGACGCCCACTTCGACGAGCAGGTGAAGCTGCTGCAGGAGCTGGTGAAG
GTGCCCACCGACTCGCCGCC

Product: putative bifunctional OHCU decarboxylase/allantoate amidohydrolase

Products: NA

Alternate protein names: L-carbamoylase [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTTAAPTPLTLAWLNDAPAEAALAALDGLYEHSPWIAEAALRQRPFTSLAQLKHAMVRVVREAGREAQLALVRAHPELAG
KAAVAGTLTAESTGEQARAGLNHCSPEEFALVQRLNAEYGARFGWPFVLAVRGPRGEGLHRREILATLQRRLQGHPEIEL
VECLRNIDRIAEIRLNDKFGAAPILGNPVWDWAEQLAVHTDPGYGERGELTVTYLTDAHRACAAQLQAWMRDCGFDEVRL
DAVGNVVGLYLGSDPSARRLLTGSHYDTVRNGGKYDGRLGILVPMACVRELHRAGRRLPFGLEVVGFAEEEGQRYKATFL
GSGALTGHFEPAWLDQQDADGVTMRTAMLAAGLPATLEAIAAEARDAARYLGFVEVHIEQGPVLAELDLPLGVVSSINGS
VRYLGEVVGVASHAGTTPMDRRRDAATAVAELALYVEQRAAAAPHLVGTVGMLEVPNGSINVVPGRCRFSIDIRSTTNEV
RDAMAADVRERLAAICERRGLAYRLEETVRAAAAPSDAAWQRRWEAAVAATGLPVHRLPSGAGHDAMKLHEVMPQAMLFV
RGENAGISHNPLESTTADDMQLAVEAFTHLLDALSHDTP

Sequences:

>Translated_599_residues
MTTAAPTPLTLAWLNDAPAEAALAALDGLYEHSPWIAEAALRQRPFTSLAQLKHAMVRVVREAGREAQLALVRAHPELAG
KAAVAGTLTAESTGEQARAGLNHCSPEEFALVQRLNAEYGARFGWPFVLAVRGPRGEGLHRREILATLQRRLQGHPEIEL
VECLRNIDRIAEIRLNDKFGAAPILGNPVWDWAEQLAVHTDPGYGERGELTVTYLTDAHRACAAQLQAWMRDCGFDEVRL
DAVGNVVGLYLGSDPSARRLLTGSHYDTVRNGGKYDGRLGILVPMACVRELHRAGRRLPFGLEVVGFAEEEGQRYKATFL
GSGALTGHFEPAWLDQQDADGVTMRTAMLAAGLPATLEAIAAEARDAARYLGFVEVHIEQGPVLAELDLPLGVVSSINGS
VRYLGEVVGVASHAGTTPMDRRRDAATAVAELALYVEQRAAAAPHLVGTVGMLEVPNGSINVVPGRCRFSIDIRSTTNEV
RDAMAADVRERLAAICERRGLAYRLEETVRAAAAPSDAAWQRRWEAAVAATGLPVHRLPSGAGHDAMKLHEVMPQAMLFV
RGENAGISHNPLESTTADDMQLAVEAFTHLLDALSHDTP
>Mature_598_residues
TTAAPTPLTLAWLNDAPAEAALAALDGLYEHSPWIAEAALRQRPFTSLAQLKHAMVRVVREAGREAQLALVRAHPELAGK
AAVAGTLTAESTGEQARAGLNHCSPEEFALVQRLNAEYGARFGWPFVLAVRGPRGEGLHRREILATLQRRLQGHPEIELV
ECLRNIDRIAEIRLNDKFGAAPILGNPVWDWAEQLAVHTDPGYGERGELTVTYLTDAHRACAAQLQAWMRDCGFDEVRLD
AVGNVVGLYLGSDPSARRLLTGSHYDTVRNGGKYDGRLGILVPMACVRELHRAGRRLPFGLEVVGFAEEEGQRYKATFLG
SGALTGHFEPAWLDQQDADGVTMRTAMLAAGLPATLEAIAAEARDAARYLGFVEVHIEQGPVLAELDLPLGVVSSINGSV
RYLGEVVGVASHAGTTPMDRRRDAATAVAELALYVEQRAAAAPHLVGTVGMLEVPNGSINVVPGRCRFSIDIRSTTNEVR
DAMAADVRERLAAICERRGLAYRLEETVRAAAAPSDAAWQRRWEAAVAATGLPVHRLPSGAGHDAMKLHEVMPQAMLFVR
GENAGISHNPLESTTADDMQLAVEAFTHLLDALSHDTP

Specific function: Involved In The Anaerobic Utilization Of Allantoin. Converts Allantoate To (S)-Ureidoglycolate And Ammonia. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Homo sapiens, GI157743280, Length=153, Percent_Identity=38.562091503268, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1786726, Length=361, Percent_Identity=33.7950138504155, Blast_Score=166, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010158
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.87 [H]

Molecular weight: Translated: 64673; Mature: 64542

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAAPTPLTLAWLNDAPAEAALAALDGLYEHSPWIAEAALRQRPFTSLAQLKHAMVRVV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
REAGREAQLALVRAHPELAGKAAVAGTLTAESTGEQARAGLNHCSPEEFALVQRLNAEYG
HHCCCCEEEEEEECCHHHCCCHHHEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHC
ARFGWPFVLAVRGPRGEGLHRREILATLQRRLQGHPEIELVECLRNIDRIAEIRLNDKFG
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCC
AAPILGNPVWDWAEQLAVHTDPGYGERGELTVTYLTDAHRACAAQLQAWMRDCGFDEVRL
CCCCCCCCHHHHHHHHEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEH
DAVGNVVGLYLGSDPSARRLLTGSHYDTVRNGGKYDGRLGILVPMACVRELHRAGRRLPF
HHHCCEEEEEECCCCCCCCEECCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCC
GLEVVGFAEEEGQRYKATFLGSGALTGHFEPAWLDQQDADGVTMRTAMLAAGLPATLEAI
CEEEEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
AAEARDAARYLGFVEVHIEQGPVLAELDLPLGVVSSINGSVRYLGEVVGVASHAGTTPMD
HHHHHHHHHHHEEEEEEEECCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCH
RRRDAATAVAELALYVEQRAAAAPHLVGTVGMLEVPNGSINVVPGRCRFSIDIRSTTNEV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCEEEECCCEEEEEEECCCHHHH
RDAMAADVRERLAAICERRGLAYRLEETVRAAAAPSDAAWQRRWEAAVAATGLPVHRLPS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCC
GAGHDAMKLHEVMPQAMLFVRGENAGISHNPLESTTADDMQLAVEAFTHLLDALSHDTP
CCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTAAPTPLTLAWLNDAPAEAALAALDGLYEHSPWIAEAALRQRPFTSLAQLKHAMVRVV
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
REAGREAQLALVRAHPELAGKAAVAGTLTAESTGEQARAGLNHCSPEEFALVQRLNAEYG
HHCCCCEEEEEEECCHHHCCCHHHEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHC
ARFGWPFVLAVRGPRGEGLHRREILATLQRRLQGHPEIELVECLRNIDRIAEIRLNDKFG
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCC
AAPILGNPVWDWAEQLAVHTDPGYGERGELTVTYLTDAHRACAAQLQAWMRDCGFDEVRL
CCCCCCCCHHHHHHHHEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEH
DAVGNVVGLYLGSDPSARRLLTGSHYDTVRNGGKYDGRLGILVPMACVRELHRAGRRLPF
HHHCCEEEEEECCCCCCCCEECCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCC
GLEVVGFAEEEGQRYKATFLGSGALTGHFEPAWLDQQDADGVTMRTAMLAAGLPATLEAI
CEEEEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
AAEARDAARYLGFVEVHIEQGPVLAELDLPLGVVSSINGSVRYLGEVVGVASHAGTTPMD
HHHHHHHHHHHEEEEEEEECCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCH
RRRDAATAVAELALYVEQRAAAAPHLVGTVGMLEVPNGSINVVPGRCRFSIDIRSTTNEV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCEEEECCCEEEEEEECCCHHHH
RDAMAADVRERLAAICERRGLAYRLEETVRAAAAPSDAAWQRRWEAAVAATGLPVHRLPS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCC
GAGHDAMKLHEVMPQAMLFVRGENAGISHNPLESTTADDMQLAVEAFTHLLDALSHDTP
CCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9023955; 8285691 [H]