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The map label for this gene is yodQ [H]

Identifier: 124265968

GI number: 124265968

Start: 809127

End: 810356

Strand: Reverse

Name: yodQ [H]

Synonym: Mpe_A0775

Alternate gene names: 124265968

Gene position: 810356-809127 (Counterclockwise)

Preceding gene: 124265969

Following gene: 124265967

Centisome position: 20.04

GC content: 69.67

Gene sequence:

>1230_bases
ATGAGCACCCCCCACGACCGACTCGACGCCTGGATCGACGCCCACTTCGACGAGCAGGTGAAGCTGCTGCAGGAGCTGGT
GAAGGTGCCCACCGACTCGCCGCCCGGCAACAACGCGCCGCACGCCGAGCGCACCGCCGAACTGCTGGCGGCCTTCGGCT
TCGAGGCCGAAAAGTACCCGGTGCCGGCCGACGAGGTGCGCGCCTACGGCCTGGAGTCGCTCACCAACCTGATCGTGCGG
CGTCGCTACGGCGCCGGTGGTCCGACCATCGCGCTCAACGCCCACGGCGACGTGGTGCCGCCCGGCGAGGGCTGGACGCA
TGATCCCTACGGCGGCGAAGTCGCCGACGGCAGGCTCTACGGCCGCGCCGCCGCGGTCAGCAAGTGCGACTTCACGACCT
ACAGCTTCGCGGTGCGCGCGATCGAGTCGCTCGGCGCGCCGCTGAAGGGCGGTGTCGAGCTGCACTTCACCTACGACGAG
GAATTCGGCGGCGAGCTCGGCCCCGGCCGGCTGCTGGCCCAGGGCCTCACCCAGCCCGACCTGATGATGGCCGCCGGCTT
CAGCTACCAGATCGTCACCGCGCACAACGGCTGCCTGCAGATGGAGGTCACGGTGCACGGCAGGATGGCCCACGCCGCGA
TCCCCCACACCGGTGTCGACGCGCTGCAGGGCGCGGTGAAGATCCTGAACGCGCTGTATGCGCAGAACACCCTCTACAAG
AGCATCTCCTCGAAGGTACCAGGCATCACCCATCCCTATCTCAACGTCGGGATGATCGAGGGCGGCACCAACACCAACGT
CGTGCCCGGCAAGGTGGTGTTCAAGCTCGACCGCCGGATGATCCCCGAGGAGAACCCCGAGCAGGTCGAGGCCGACATCC
GCCGCGTGATCGCCGATGCCGCCGCGCAGACCGACGGCATCACCGTCGACATCCGCCGCATGCTGATGTGCCGCGCGCTC
ACGCCGCTGCCCGGCAACGCGCCGCTGGTGGCCGCGCTGGAGAAGCAGGCCTCGGCGGTGTTCGGCGAACCGATCCGCAC
CACCGGCACGCCGCTCTACACCGACGTGCGGCTGTACTGCGAGCACGGCGTGCCGGCCGTCATCTACGGCGCCGGGCCGC
GCACCGTGCTGGAGAGCAACGCCAAGCGTGCCGACGAGCACATCGTGCTCGACGACCTGCGGCGCGCGACCAAGGTCGTC
GCACGCACGCTGTACGAGCTGCTGGGCTGA

Upstream 100 bases:

>100_bases
GCATCAGCCACAACCCGCTCGAATCCACCACGGCCGACGACATGCAGCTTGCGGTCGAGGCCTTCACGCACCTGCTCGAC
GCCCTGAGCCACGACACGCC

Downstream 100 bases:

>100_bases
GATGCATGCGTTCCGCCACCCCGACCCCAGCGCCGCGCAGATCGCCGCCGCGCTGCACCGTGCCAATGCCGTCGCGCTGA
GCGCGCTGGCGCTTGGCCGG

Product: hypothetical protein

Products: Acetate; Ornithine [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSTPHDRLDAWIDAHFDEQVKLLQELVKVPTDSPPGNNAPHAERTAELLAAFGFEAEKYPVPADEVRAYGLESLTNLIVR
RRYGAGGPTIALNAHGDVVPPGEGWTHDPYGGEVADGRLYGRAAAVSKCDFTTYSFAVRAIESLGAPLKGGVELHFTYDE
EFGGELGPGRLLAQGLTQPDLMMAAGFSYQIVTAHNGCLQMEVTVHGRMAHAAIPHTGVDALQGAVKILNALYAQNTLYK
SISSKVPGITHPYLNVGMIEGGTNTNVVPGKVVFKLDRRMIPEENPEQVEADIRRVIADAAAQTDGITVDIRRMLMCRAL
TPLPGNAPLVAALEKQASAVFGEPIRTTGTPLYTDVRLYCEHGVPAVIYGAGPRTVLESNAKRADEHIVLDDLRRATKVV
ARTLYELLG

Sequences:

>Translated_409_residues
MSTPHDRLDAWIDAHFDEQVKLLQELVKVPTDSPPGNNAPHAERTAELLAAFGFEAEKYPVPADEVRAYGLESLTNLIVR
RRYGAGGPTIALNAHGDVVPPGEGWTHDPYGGEVADGRLYGRAAAVSKCDFTTYSFAVRAIESLGAPLKGGVELHFTYDE
EFGGELGPGRLLAQGLTQPDLMMAAGFSYQIVTAHNGCLQMEVTVHGRMAHAAIPHTGVDALQGAVKILNALYAQNTLYK
SISSKVPGITHPYLNVGMIEGGTNTNVVPGKVVFKLDRRMIPEENPEQVEADIRRVIADAAAQTDGITVDIRRMLMCRAL
TPLPGNAPLVAALEKQASAVFGEPIRTTGTPLYTDVRLYCEHGVPAVIYGAGPRTVLESNAKRADEHIVLDDLRRATKVV
ARTLYELLG
>Mature_408_residues
STPHDRLDAWIDAHFDEQVKLLQELVKVPTDSPPGNNAPHAERTAELLAAFGFEAEKYPVPADEVRAYGLESLTNLIVRR
RYGAGGPTIALNAHGDVVPPGEGWTHDPYGGEVADGRLYGRAAAVSKCDFTTYSFAVRAIESLGAPLKGGVELHFTYDEE
FGGELGPGRLLAQGLTQPDLMMAAGFSYQIVTAHNGCLQMEVTVHGRMAHAAIPHTGVDALQGAVKILNALYAQNTLYKS
ISSKVPGITHPYLNVGMIEGGTNTNVVPGKVVFKLDRRMIPEENPEQVEADIRRVIADAAAQTDGITVDIRRMLMCRALT
PLPGNAPLVAALEKQASAVFGEPIRTTGTPLYTDVRLYCEHGVPAVIYGAGPRTVLESNAKRADEHIVLDDLRRATKVVA
RTLYELLG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=325, Percent_Identity=26.1538461538462, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790395, Length=308, Percent_Identity=26.6233766233766, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788816, Length=286, Percent_Identity=25.1748251748252, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356353, Length=412, Percent_Identity=24.5145631067961, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649202, Length=367, Percent_Identity=26.158038147139, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24649204, Length=367, Percent_Identity=26.158038147139, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24649206, Length=370, Percent_Identity=25.6756756756757, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24649210, Length=370, Percent_Identity=24.5945945945946, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24649208, Length=388, Percent_Identity=24.2268041237113, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16 [C]

Molecular weight: Translated: 44122; Mature: 43991

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPHDRLDAWIDAHFDEQVKLLQELVKVPTDSPPGNNAPHAERTAELLAAFGFEAEKYP
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
VPADEVRAYGLESLTNLIVRRRYGAGGPTIALNAHGDVVPPGEGWTHDPYGGEVADGRLY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
GRAAAVSKCDFTTYSFAVRAIESLGAPLKGGVELHFTYDEEFGGELGPGRLLAQGLTQPD
CHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHCCCCCCHHHHHHCCCCCC
LMMAAGFSYQIVTAHNGCLQMEVTVHGRMAHAAIPHTGVDALQGAVKILNALYAQNTLYK
HHEECCCCEEEEEECCCEEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SISSKVPGITHPYLNVGMIEGGTNTNVVPGKVVFKLDRRMIPEENPEQVEADIRRVIADA
HHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHEEEHHHCCCCCCHHHHHHHHHHHHHHH
AAQTDGITVDIRRMLMCRALTPLPGNAPLVAALEKQASAVFGEPIRTTGTPLYTDVRLYC
HHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEE
EHGVPAVIYGAGPRTVLESNAKRADEHIVLDDLRRATKVVARTLYELLG
CCCCCEEEECCCCHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
STPHDRLDAWIDAHFDEQVKLLQELVKVPTDSPPGNNAPHAERTAELLAAFGFEAEKYP
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
VPADEVRAYGLESLTNLIVRRRYGAGGPTIALNAHGDVVPPGEGWTHDPYGGEVADGRLY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
GRAAAVSKCDFTTYSFAVRAIESLGAPLKGGVELHFTYDEEFGGELGPGRLLAQGLTQPD
CHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHCCCCCCHHHHHHCCCCCC
LMMAAGFSYQIVTAHNGCLQMEVTVHGRMAHAAIPHTGVDALQGAVKILNALYAQNTLYK
HHEECCCCEEEEEECCCEEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SISSKVPGITHPYLNVGMIEGGTNTNVVPGKVVFKLDRRMIPEENPEQVEADIRRVIADA
HHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHEEEHHHCCCCCCHHHHHHHHHHHHHHH
AAQTDGITVDIRRMLMCRALTPLPGNAPLVAALEKQASAVFGEPIRTTGTPLYTDVRLYC
HHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEE
EHGVPAVIYGAGPRTVLESNAKRADEHIVLDDLRRATKVVARTLYELLG
CCCCCEEEECCCCHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-Acetyl-L-ornithine; H2O [C]

Specific reaction: N2-Acetyl-L-ornithine + H2O --> Acetate + Ornithine [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]