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The map label for this gene is cph1 [H]

Identifier: 124265942

GI number: 124265942

Start: 776164

End: 777957

Strand: Reverse

Name: cph1 [H]

Synonym: Mpe_A0749

Alternate gene names: 124265942

Gene position: 777957-776164 (Counterclockwise)

Preceding gene: 124265943

Following gene: 124265938

Centisome position: 19.24

GC content: 69.9

Gene sequence:

>1794_bases
ATGGATTCGGTCTTTCGACGTCGGGCAACGCAGGTCGCGCTGGGCATCGGCGCGATCTACATCGTCGCCGGCATCGCCTG
GATCCTGCTGTCCGATGCGCTGGTGCTCCAGGTCTCGAACGACATCGACTGGCTGACGTTCACCCAGCGCTACAAGGGCA
TCGCCTACGTGCTCTTGAGCGGCCTGCTGGTCGTCGCGCTGGTGCGCACCGGCAACCTGGCGCTGCTGAAGGCCCAGCAG
CGGCTGCACATCGGCGAGGTGCGGGTGCAGGACCTGTTCCAGCACCACCCGAAGCCGATGTGGGCCTTCGACGAGGAGAC
GCTGCGCTTCATCGCGGTGAACCACGCCGCGGTCGCGCACTACGGCTATACCGAGGCCGAGTTCCTGGGCATGCTGGCCA
CCGACATTCGCCCGCCCGAGGACGTGCCGCAGATGATGCGCCTGCTGAGCGAGACGCTGACGCCGCACCACGATGCCGGC
ATCGTGCGTCACCGCAAGAAGAACGGCGAGCTGTGCCATGTGCACGTGAGCCTGCACCGCATGCGCATCCGGCACCGCGA
CAGCGTGCTGGTGATCGCCGACGACGTGACCGACGAGGTCCGCACGCGCGACGCGCTCAAGCGCCAGGAACTGCAGTTCC
GCCAGCTGCACGACAGCCTGCAGGAAGCGCTGTGGATCGGCAAGGACGACGTGCGCGAGATGCTCTATGCGAGCCCGGCG
TTCCTGACGATCTGCGGCCACTCCGCGCGCTCGCTGCTGCAGGACCGCACGCTGTGGCTGTCGCTGGTGCACCCGGAGGA
CCGGCCGATCGCCGAGGAATCGCTGCTCAACCTGGTGGCGTTCGGCAGCGCGCAGTGCGAGTACCGCATCTGCCGTCCGG
ACGGCAGCGTGCGCTGGGTGGCCGACCGCAAGCGCCGCATCGTCGACGCGAGCGACGGCTCGCGGCTGGTGGGCGGGATC
ATCGAGGACATCACCGACGTCCGGGCGGCCGCGCAGGCCCTGCGCGACGCCAACGAGCAGCTGGAGGAACGCGTGCAGGC
CCGCACCGCCGCGCTGCAGTTCGCCAACGACGAGCTCGACGCCTTCGCCCGCACGGCCGCCCACGACCTGAAGACACCGC
TGAACGCCATCATCGGATTCATCGGCCTGCTGCGGGCACGCTATGCGCCGGCGCTGGGCCCCGAGGGGGACCGGATGAGC
GCGCTGGTGGAAAGCTCGGCGCGCGGCATGAACCACCTGATCAACGACCTGCTGGCGTTGTCGCAGGTGGCGACGCACCA
GTTGCAACCGGTGTCCGTGGACCTGAGCGCCATCGCCCGCGAAGTGGTGGCCGAGCTGCGGCAGTCCGAGCCCGGCCGCC
AGGCCGAGGTGAGGATCGAGGACGGGCTGCACGCGCAGGCCGACCCCGGACTGGCCCGCTCGCTGCTCATGAACCTGATC
GGCAACGCCTGGAAGTACTCGGGCAAGCGCGCGTGCGCCGAGATCGAGGTGGGCCGTGTCGAGTCGCCGGACGGCACGGA
GTTCTTCGTGCGCGACAACGGCGCCGGCTTCGACACGCGGCAGGCGGACAAGCTCTTCAAGCCCTTCCAGCGGCTGCACG
AAGCGTCGGAGTTCAGCGGCACCGGCGTCGGGCTGGCCACCTGCCAGCGCATCGTGCGCCGCCATGGCGGGCACATCCGC
CTGAGCTCGCAGCCCGACGTGGGCACCACGGTGTTCTTCTCGCTCTCCGGCCGCGCCAGGACGCGCCCGGCCGACGAGCC
GCCGCGCGACTCGGGCTTCGCGCGGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCGCCACCCCGCACGAAGCGCCGCGACATCGCTGATCGCGGGCACCCGCCCGGCGTTACAGTCGGCGCTTCGTCCTGT
TCCCGGGGGCTGAGCGCCGC

Downstream 100 bases:

>100_bases
CCTGACCGGCAGCGGACGCGCCGGCGAGGGCTCAGGCGGTCGGCGTACCGCGCTGCTCCGCCACGTGTTCGCGCAGCAGG
GCGATCCGCAGCCGGCAGCG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MDSVFRRRATQVALGIGAIYIVAGIAWILLSDALVLQVSNDIDWLTFTQRYKGIAYVLLSGLLVVALVRTGNLALLKAQQ
RLHIGEVRVQDLFQHHPKPMWAFDEETLRFIAVNHAAVAHYGYTEAEFLGMLATDIRPPEDVPQMMRLLSETLTPHHDAG
IVRHRKKNGELCHVHVSLHRMRIRHRDSVLVIADDVTDEVRTRDALKRQELQFRQLHDSLQEALWIGKDDVREMLYASPA
FLTICGHSARSLLQDRTLWLSLVHPEDRPIAEESLLNLVAFGSAQCEYRICRPDGSVRWVADRKRRIVDASDGSRLVGGI
IEDITDVRAAAQALRDANEQLEERVQARTAALQFANDELDAFARTAAHDLKTPLNAIIGFIGLLRARYAPALGPEGDRMS
ALVESSARGMNHLINDLLALSQVATHQLQPVSVDLSAIAREVVAELRQSEPGRQAEVRIEDGLHAQADPGLARSLLMNLI
GNAWKYSGKRACAEIEVGRVESPDGTEFFVRDNGAGFDTRQADKLFKPFQRLHEASEFSGTGVGLATCQRIVRRHGGHIR
LSSQPDVGTTVFFSLSGRARTRPADEPPRDSGFARLA

Sequences:

>Translated_597_residues
MDSVFRRRATQVALGIGAIYIVAGIAWILLSDALVLQVSNDIDWLTFTQRYKGIAYVLLSGLLVVALVRTGNLALLKAQQ
RLHIGEVRVQDLFQHHPKPMWAFDEETLRFIAVNHAAVAHYGYTEAEFLGMLATDIRPPEDVPQMMRLLSETLTPHHDAG
IVRHRKKNGELCHVHVSLHRMRIRHRDSVLVIADDVTDEVRTRDALKRQELQFRQLHDSLQEALWIGKDDVREMLYASPA
FLTICGHSARSLLQDRTLWLSLVHPEDRPIAEESLLNLVAFGSAQCEYRICRPDGSVRWVADRKRRIVDASDGSRLVGGI
IEDITDVRAAAQALRDANEQLEERVQARTAALQFANDELDAFARTAAHDLKTPLNAIIGFIGLLRARYAPALGPEGDRMS
ALVESSARGMNHLINDLLALSQVATHQLQPVSVDLSAIAREVVAELRQSEPGRQAEVRIEDGLHAQADPGLARSLLMNLI
GNAWKYSGKRACAEIEVGRVESPDGTEFFVRDNGAGFDTRQADKLFKPFQRLHEASEFSGTGVGLATCQRIVRRHGGHIR
LSSQPDVGTTVFFSLSGRARTRPADEPPRDSGFARLA
>Mature_597_residues
MDSVFRRRATQVALGIGAIYIVAGIAWILLSDALVLQVSNDIDWLTFTQRYKGIAYVLLSGLLVVALVRTGNLALLKAQQ
RLHIGEVRVQDLFQHHPKPMWAFDEETLRFIAVNHAAVAHYGYTEAEFLGMLATDIRPPEDVPQMMRLLSETLTPHHDAG
IVRHRKKNGELCHVHVSLHRMRIRHRDSVLVIADDVTDEVRTRDALKRQELQFRQLHDSLQEALWIGKDDVREMLYASPA
FLTICGHSARSLLQDRTLWLSLVHPEDRPIAEESLLNLVAFGSAQCEYRICRPDGSVRWVADRKRRIVDASDGSRLVGGI
IEDITDVRAAAQALRDANEQLEERVQARTAALQFANDELDAFARTAAHDLKTPLNAIIGFIGLLRARYAPALGPEGDRMS
ALVESSARGMNHLINDLLALSQVATHQLQPVSVDLSAIAREVVAELRQSEPGRQAEVRIEDGLHAQADPGLARSLLMNLI
GNAWKYSGKRACAEIEVGRVESPDGTEFFVRDNGAGFDTRQADKLFKPFQRLHEASEFSGTGVGLATCQRIVRRHGGHIR
LSSQPDVGTTVFFSLSGRARTRPADEPPRDSGFARLA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=326, Percent_Identity=26.6871165644172, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=28.8537549407115, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=31.6279069767442, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788713, Length=276, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=30.8411214953271, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=26.1224489795918, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=282, Percent_Identity=26.9503546099291, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=300, Percent_Identity=26, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66438; Mature: 66438

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVFRRRATQVALGIGAIYIVAGIAWILLSDALVLQVSNDIDWLTFTQRYKGIAYVLLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHH
GLLVVALVRTGNLALLKAQQRLHIGEVRVQDLFQHHPKPMWAFDEETLRFIAVNHAAVAH
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEECCHHHHH
YGYTEAEFLGMLATDIRPPEDVPQMMRLLSETLTPHHDAGIVRHRKKNGELCHVHVSLHR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEHHHHH
MRIRHRDSVLVIADDVTDEVRTRDALKRQELQFRQLHDSLQEALWIGKDDVREMLYASPA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
FLTICGHSARSLLQDRTLWLSLVHPEDRPIAEESLLNLVAFGSAQCEYRICRPDGSVRWV
CEEEECHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
ADRKRRIVDASDGSRLVGGIIEDITDVRAAAQALRDANEQLEERVQARTAALQFANDELD
ECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFARTAAHDLKTPLNAIIGFIGLLRARYAPALGPEGDRMSALVESSARGMNHLINDLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SQVATHQLQPVSVDLSAIAREVVAELRQSEPGRQAEVRIEDGLHAQADPGLARSLLMNLI
HHHHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
GNAWKYSGKRACAEIEVGRVESPDGTEFFVRDNGAGFDTRQADKLFKPFQRLHEASEFSG
HHHHHCCCCCCHHEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TGVGLATCQRIVRRHGGHIRLSSQPDVGTTVFFSLSGRARTRPADEPPRDSGFARLA
CCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSVFRRRATQVALGIGAIYIVAGIAWILLSDALVLQVSNDIDWLTFTQRYKGIAYVLLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHH
GLLVVALVRTGNLALLKAQQRLHIGEVRVQDLFQHHPKPMWAFDEETLRFIAVNHAAVAH
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEECCHHHHH
YGYTEAEFLGMLATDIRPPEDVPQMMRLLSETLTPHHDAGIVRHRKKNGELCHVHVSLHR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEHHHHH
MRIRHRDSVLVIADDVTDEVRTRDALKRQELQFRQLHDSLQEALWIGKDDVREMLYASPA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
FLTICGHSARSLLQDRTLWLSLVHPEDRPIAEESLLNLVAFGSAQCEYRICRPDGSVRWV
CEEEECHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
ADRKRRIVDASDGSRLVGGIIEDITDVRAAAQALRDANEQLEERVQARTAALQFANDELD
ECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFARTAAHDLKTPLNAIIGFIGLLRARYAPALGPEGDRMSALVESSARGMNHLINDLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SQVATHQLQPVSVDLSAIAREVVAELRQSEPGRQAEVRIEDGLHAQADPGLARSLLMNLI
HHHHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
GNAWKYSGKRACAEIEVGRVESPDGTEFFVRDNGAGFDTRQADKLFKPFQRLHEASEFSG
HHHHHCCCCCCHHEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TGVGLATCQRIVRRHGGHIRLSSQPDVGTTVFFSLSGRARTRPADEPPRDSGFARLA
CCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]