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The map label for this gene is livM [C]

Identifier: 124265892

GI number: 124265892

Start: 729538

End: 730674

Strand: Direct

Name: livM [C]

Synonym: Mpe_A0699

Alternate gene names: 124265892

Gene position: 729538-730674 (Clockwise)

Preceding gene: 124265891

Following gene: 124265893

Centisome position: 18.04

GC content: 66.31

Gene sequence:

>1137_bases
ATGAGTGCCGTGCTGACGCCTCCTCTGCCCGTGGCACCGCCGCGCAGTCGCCTGCTGCAGGGCAAGGCCTGGACGGCGCT
GCTGGCCGCGGTGATCACCGTGACCGTGCTGGTGCCGGTGCTGAACCTCGTGGTGCCGGCCGGCAGCGCCTTCCACCTGA
GCGACTACGCGGTGGCGCTGATCGGCAAGATCATGTGCTACGCGATCTGCGCGCTGGCCATGGACCTGATCTGGGGCTAC
ACCGGCATCCTGTCGCTCGGCCACGGCCTGTTCTTCGCGCTCGGCGGCTACGCGATGGGCATGTACCTCATGCGCCAGAT
CGGCCGCGACGGCAACTACCAGTCGGACCTGCCCGACTTCATGGTCTTCCTCGACTGGAAGGAGCTGCCCTGGCACTGGA
GCTTCAGCGACTCCTTCGTGGCCACGCTGTTCCTGATCGTCGCGGTGCCGGGCCTGCTGGCCTTCGTGTTCGGCTTCTTC
GCGTTCCGCTCGCGCATCAAGGGCGTGTACTTCTCGATCATCACGCAGGCGCTCACCTTCGCCGCGATGCTGCTGTTCTT
TCGCAACGAAACCGGCTTCGGCGGCAACAATGGCTTCACCGACTTCAAGCGCATCCTCTCCATCCCGATTGCGCAGCCGT
CCACGCGCATGGTGCTGTTCGTGCTGACCGGGCTCACGCTGATCGGCTTCTTCCTGCTGGCGCGCTGGCTCATCCACACC
AAGTTCGGCCGCGTGCTGCAGGCCATCCGCGACGCCGAGAACCGCGTCATGTTCTGCGGCTACGAGCCGCTGAACTACAA
GCTCGCGATCTGGACGCTGTCGGCGGTGATGTGCGGCATCGCCGGTGCGCTGTACGTGCCGCAGGTGGGCATCATCAACC
CGGGCGAGATGTCGCCGGCCGCCAGCATCGAGATCGCGATCTGGGCCGCGGTGGGCGGCCGCGCCACGCTGATCGGCCCG
ATCGTCGGTGCCTTCTTCGTCAACTTCGCGAAGAGCTGGTTCACGCAGGTCTTCCCCGAGTTCTGGCTGTACTTCCTGGG
CGCGCTGTTCATCGCCGTCACGCTGTTCCTGCCGGACGGCATCGTCGGCGGCGTGAAGCGGCTGCTGGGCCGCGGCAGCA
AGGAGAAGCGCGCATGA

Upstream 100 bases:

>100_bases
GGGCCGGCGCCGTGCTGGCGAAGATCATCGTGCTGGTGTTCATCGTGGTGTTCATCCAGAAGCGGCCGCAGGGGCTGTTC
GCATTGAAGGGGAGAGAGGC

Downstream 100 bases:

>100_bases
CGCCCGAGCTGATGGAGGCCGGCGCCCGCACCCGCGAGCGCATGGCCGCGAAGCCCGAGGCCGGCAAGTCGGGCGGCCGG
GCGGCGAGCTACAGCCGTGT

Product: putative permease transporter transmembrane protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Urea ABC Transporter Permease Protein UrtC; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter ; ABC Transporter Permease; ABC Transporter; Branched-Chain Amino Acid Transporter; Urea ABC Transporter Permease; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched-Chain Amino Acid Transport Permease; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Membrane Protein; ABC-Type Urea Transport System Permease Protein II; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC-Type Transport System Permease Protein; Amino Acid ABC Transporter Permease Protein; ABC Transporter-Like Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; ABC Branched Amino Acid Transporter Permease Component; Branched-Chain Amino Acid Transport System Permease; Amino Acid/Amide ABC Transporter Membrane HAAT Family; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Component Of ABC Transporter; Urea Or Short-Chain Amide ABC Transporter; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC; Branched Chain Amino Acid ABC Transporter

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSAVLTPPLPVAPPRSRLLQGKAWTALLAAVITVTVLVPVLNLVVPAGSAFHLSDYAVALIGKIMCYAICALAMDLIWGY
TGILSLGHGLFFALGGYAMGMYLMRQIGRDGNYQSDLPDFMVFLDWKELPWHWSFSDSFVATLFLIVAVPGLLAFVFGFF
AFRSRIKGVYFSIITQALTFAAMLLFFRNETGFGGNNGFTDFKRILSIPIAQPSTRMVLFVLTGLTLIGFFLLARWLIHT
KFGRVLQAIRDAENRVMFCGYEPLNYKLAIWTLSAVMCGIAGALYVPQVGIINPGEMSPAASIEIAIWAAVGGRATLIGP
IVGAFFVNFAKSWFTQVFPEFWLYFLGALFIAVTLFLPDGIVGGVKRLLGRGSKEKRA

Sequences:

>Translated_378_residues
MSAVLTPPLPVAPPRSRLLQGKAWTALLAAVITVTVLVPVLNLVVPAGSAFHLSDYAVALIGKIMCYAICALAMDLIWGY
TGILSLGHGLFFALGGYAMGMYLMRQIGRDGNYQSDLPDFMVFLDWKELPWHWSFSDSFVATLFLIVAVPGLLAFVFGFF
AFRSRIKGVYFSIITQALTFAAMLLFFRNETGFGGNNGFTDFKRILSIPIAQPSTRMVLFVLTGLTLIGFFLLARWLIHT
KFGRVLQAIRDAENRVMFCGYEPLNYKLAIWTLSAVMCGIAGALYVPQVGIINPGEMSPAASIEIAIWAAVGGRATLIGP
IVGAFFVNFAKSWFTQVFPEFWLYFLGALFIAVTLFLPDGIVGGVKRLLGRGSKEKRA
>Mature_377_residues
SAVLTPPLPVAPPRSRLLQGKAWTALLAAVITVTVLVPVLNLVVPAGSAFHLSDYAVALIGKIMCYAICALAMDLIWGYT
GILSLGHGLFFALGGYAMGMYLMRQIGRDGNYQSDLPDFMVFLDWKELPWHWSFSDSFVATLFLIVAVPGLLAFVFGFFA
FRSRIKGVYFSIITQALTFAAMLLFFRNETGFGGNNGFTDFKRILSIPIAQPSTRMVLFVLTGLTLIGFFLLARWLIHTK
FGRVLQAIRDAENRVMFCGYEPLNYKLAIWTLSAVMCGIAGALYVPQVGIINPGEMSPAASIEIAIWAAVGGRATLIGPI
VGAFFVNFAKSWFTQVFPEFWLYFLGALFIAVTLFLPDGIVGGVKRLLGRGSKEKRA

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=338, Percent_Identity=22.7810650887574, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41461; Mature: 41330

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAVLTPPLPVAPPRSRLLQGKAWTALLAAVITVTVLVPVLNLVVPAGSAFHLSDYAVAL
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
IGKIMCYAICALAMDLIWGYTGILSLGHGLFFALGGYAMGMYLMRQIGRDGNYQSDLPDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
MVFLDWKELPWHWSFSDSFVATLFLIVAVPGLLAFVFGFFAFRSRIKGVYFSIITQALTF
HEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMLLFFRNETGFGGNNGFTDFKRILSIPIAQPSTRMVLFVLTGLTLIGFFLLARWLIHT
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGRVLQAIRDAENRVMFCGYEPLNYKLAIWTLSAVMCGIAGALYVPQVGIINPGEMSPA
HHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ASIEIAIWAAVGGRATLIGPIVGAFFVNFAKSWFTQVFPEFWLYFLGALFIAVTLFLPDG
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IVGGVKRLLGRGSKEKRA
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA