BacMap

Definition	Methylibium petroleiphilum PM1 chromosome, complete genome.
Accession	NC_008825
Length	4,044,195

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The map label for this gene is livG [H]

Identifier: 124265893

GI number: 124265893

Start: 730671

End: 731555

Strand: Direct

Name: livG [H]

Synonym: Mpe_A0700

Alternate gene names: 124265893

Gene position: 730671-731555 (Clockwise)

Preceding gene: 124265892

Following gene: 124265894

Centisome position: 18.07

GC content: 69.72

Gene sequence:

>885_bases
ATGACGCCCGAGCTGATGGAGGCCGGCGCCCGCACCCGCGAGCGCATGGCCGCGAAGCCCGAGGCCGGCAAGTCGGGCGG
CCGGGCGGCGAGCTACAGCCGTGTGGTCGAGCCGGGCACGCTGGACACCGCGCACGGCGGCATCCTGTACCTGGAGGACA
TCACCGTCAGCTTCGACGGCTTCCGCGCGCTGAACAAGCTGTCGCTGAACATCGCCGCCGGCGAGCTGCGCTGCATCATC
GGCCCCAACGGCGCCGGCAAGACGACCATGATGGACGTGATCACCGGCAAGACGCGGCCCGACGCCGGCAGCGCGTTCTT
CGGCTCCACCATCGACCTGCTGCGCCTGCGCGAGAGCCAGGTGGCGAGCATCGGCATCGGCCGCAAGTTCCAGAAGCCCA
GCGTGTTCGAGCAGCTCACGGTGTTCGAGAACCTGGAGCTCGCGCTGAAGGCCGACCGCCGGCCGCGCGCGGCGGTGTTC
GCCCGGCTGTCGGGCGCGCAGCTCGACCGCATCGGCGAGATCCTCACGCTCATCCACCTGAAGGGCGAGGCGCAGCGCCT
GGCCGGGCTGCTGTCGCACGGCCAGAAGCAGTGGCTGGAGATCGGCATGCTGCTGATGCAGGACCCCAAGCTGCTGCTGC
TCGACGAGCCGGTGGCCGGCATGACCGACGAGGAGACCGAGCGCACCGCGCAGCTCTTCGTGTCGCTGCAGGGCGCGCAC
TCGCTGGTGGTGGTGGAGCACGACATGAAGTTCATCGACGAGCTCACCCGCGACGACCCGGCCAAGAAGGTGACGGTGCT
GCATGAGGGCAGCGTGCTGGCCGAGGGCTCGCTCGCGCAGGTGCAGGCGAACGACAAGGTGGTGGAGGTCTATCTTGGCC
GCTGA

Upstream 100 bases:

>100_bases
TCCTGGGCGCGCTGTTCATCGCCGTCACGCTGTTCCTGCCGGACGGCATCGTCGGCGGCGTGAAGCGGCTGCTGGGCCGC
GGCAGCAAGGAGAAGCGCGC

Downstream 100 bases:

>100_bases
ACACACCATGCTGAAGGTCGAAGGCGTCAACCAGTACTACGGCGGTTCGCACATCCTGCGCGGGCTGGATTTCGAGGCGA
AGGCCGGCGAGGTGACGGTC

Product: branched-chain amino acid ABC transporter ATP-binding protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTPELMEAGARTRERMAAKPEAGKSGGRAASYSRVVEPGTLDTAHGGILYLEDITVSFDGFRALNKLSLNIAAGELRCII
GPNGAGKTTMMDVITGKTRPDAGSAFFGSTIDLLRLRESQVASIGIGRKFQKPSVFEQLTVFENLELALKADRRPRAAVF
ARLSGAQLDRIGEILTLIHLKGEAQRLAGLLSHGQKQWLEIGMLLMQDPKLLLLDEPVAGMTDEETERTAQLFVSLQGAH
SLVVVEHDMKFIDELTRDDPAKKVTVLHEGSVLAEGSLAQVQANDKVVEVYLGR

Sequences:

>Translated_294_residues
MTPELMEAGARTRERMAAKPEAGKSGGRAASYSRVVEPGTLDTAHGGILYLEDITVSFDGFRALNKLSLNIAAGELRCII
GPNGAGKTTMMDVITGKTRPDAGSAFFGSTIDLLRLRESQVASIGIGRKFQKPSVFEQLTVFENLELALKADRRPRAAVF
ARLSGAQLDRIGEILTLIHLKGEAQRLAGLLSHGQKQWLEIGMLLMQDPKLLLLDEPVAGMTDEETERTAQLFVSLQGAH
SLVVVEHDMKFIDELTRDDPAKKVTVLHEGSVLAEGSLAQVQANDKVVEVYLGR
>Mature_293_residues
TPELMEAGARTRERMAAKPEAGKSGGRAASYSRVVEPGTLDTAHGGILYLEDITVSFDGFRALNKLSLNIAAGELRCIIG
PNGAGKTTMMDVITGKTRPDAGSAFFGSTIDLLRLRESQVASIGIGRKFQKPSVFEQLTVFENLELALKADRRPRAAVFA
RLSGAQLDRIGEILTLIHLKGEAQRLAGLLSHGQKQWLEIGMLLMQDPKLLLLDEPVAGMTDEETERTAQLFVSLQGAHS
LVVVEHDMKFIDELTRDDPAKKVTVLHEGSVLAEGSLAQVQANDKVVEVYLGR

Specific function: Probable component of a branched-chain amino-acid transport system [H]

COG id: COG4674

COG function: function code R; Uncharacterized ABC-type transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=228, Percent_Identity=32.8947368421053, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27436953, Length=220, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27881501, Length=227, Percent_Identity=27.3127753303965, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI30795238, Length=227, Percent_Identity=27.3127753303965, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI116734710, Length=271, Percent_Identity=26.1992619926199, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27262624, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27262626, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31657092, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI27477115, Length=220, Percent_Identity=28.6363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI47078218, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI11967969, Length=189, Percent_Identity=29.1005291005291, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI45446740, Length=222, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI21536376, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789864, Length=255, Percent_Identity=31.7647058823529, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790190, Length=249, Percent_Identity=32.5301204819277, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790525, Length=239, Percent_Identity=28.8702928870293, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081791, Length=205, Percent_Identity=31.7073170731707, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788761, Length=241, Percent_Identity=29.045643153527, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081782, Length=219, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788897, Length=244, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787792, Length=252, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789593, Length=248, Percent_Identity=27.4193548387097, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786398, Length=247, Percent_Identity=27.5303643724696, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=27.3858921161826, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI48994943, Length=253, Percent_Identity=28.4584980237154, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790467, Length=231, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790544, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788225, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790739, Length=243, Percent_Identity=27.1604938271605, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=171, Percent_Identity=28.6549707602339, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788472, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082268, Length=253, Percent_Identity=28.8537549407115, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082267, Length=230, Percent_Identity=27.8260869565217, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787041, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786345, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790162, Length=216, Percent_Identity=26.8518518518519, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=28.3653846153846, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789586, Length=237, Percent_Identity=24.4725738396624, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787029, Length=238, Percent_Identity=25.2100840336134, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787089, Length=231, Percent_Identity=26.8398268398268, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788450, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI48995001, Length=256, Percent_Identity=26.171875, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786872, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789672, Length=242, Percent_Identity=23.1404958677686, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789991, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788210, Length=252, Percent_Identity=25.3968253968254, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787105, Length=244, Percent_Identity=27.4590163934426, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786253, Length=206, Percent_Identity=28.6407766990291, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=24.6231155778894, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787712, Length=228, Percent_Identity=25.4385964912281, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=209, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787972, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786803, Length=242, Percent_Identity=23.1404958677686, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787164, Length=230, Percent_Identity=27.3913043478261, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367384, Length=216, Percent_Identity=26.3888888888889, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=232, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71983523, Length=246, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=245, Percent_Identity=26.1224489795918, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=245, Percent_Identity=26.1224489795918, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=170, Percent_Identity=34.1176470588235, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=229, Percent_Identity=28.82096069869, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512771, Length=235, Percent_Identity=24.6808510638298, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076682, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076684, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581617, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581615, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643674, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI85726357, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 31918; Mature: 31787

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPELMEAGARTRERMAAKPEAGKSGGRAASYSRVVEPGTLDTAHGGILYLEDITVSFDG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEEEECCH
FRALNKLSLNIAAGELRCIIGPNGAGKTTMMDVITGKTRPDAGSAFFGSTIDLLRLRESQ
HHHHHHEEEEEEECEEEEEECCCCCCCCEEEHHHCCCCCCCCCCCHHCCHHHHHHHHHHH
VASIGIGRKFQKPSVFEQLTVFENLELALKADRRPRAAVFARLSGAQLDRIGEILTLIHL
HHEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHEEC
KGEAQRLAGLLSHGQKQWLEIGMLLMQDPKLLLLDEPVAGMTDEETERTAQLFVSLQGAH
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEEECCCC
SLVVVEHDMKFIDELTRDDPAKKVTVLHEGSVLAEGSLAQVQANDKVVEVYLGR
EEEEEECHHHHHHHHHCCCCCCEEEEEECCCEEECCCEEEEECCCCEEEEEECC
>Mature Secondary Structure 
TPELMEAGARTRERMAAKPEAGKSGGRAASYSRVVEPGTLDTAHGGILYLEDITVSFDG
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEEEECCH
FRALNKLSLNIAAGELRCIIGPNGAGKTTMMDVITGKTRPDAGSAFFGSTIDLLRLRESQ
HHHHHHEEEEEEECEEEEEECCCCCCCCEEEHHHCCCCCCCCCCCHHCCHHHHHHHHHHH
VASIGIGRKFQKPSVFEQLTVFENLELALKADRRPRAAVFARLSGAQLDRIGEILTLIHL
HHEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHEEC
KGEAQRLAGLLSHGQKQWLEIGMLLMQDPKLLLLDEPVAGMTDEETERTAQLFVSLQGAH
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEEECCCC
SLVVVEHDMKFIDELTRDDPAKKVTVLHEGSVLAEGSLAQVQANDKVVEVYLGR
EEEEEECHHHHHHHHHCCCCCCEEEEEECCCEEECCCEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]