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The map label for this gene is fhuA [H]

Identifier: 124265881

GI number: 124265881

Start: 718881

End: 721031

Strand: Direct

Name: fhuA [H]

Synonym: Mpe_A0688

Alternate gene names: 124265881

Gene position: 718881-721031 (Clockwise)

Preceding gene: 124265880

Following gene: 124265882

Centisome position: 17.78

GC content: 67.46

Gene sequence:

>2151_bases
ATGAACCGCCTGCATCGTGTTTCCCCGCTGACCTTCGCCTGCCTCGCCCTGGCTGCCCATGCGCAGTCCGAACCGCCTTC
CCAGGTCCTGCCGCCGGTCCAGGTGCAGGGCCAGCGCGACGACTACCGCGCCCCCGAAACCACCACCGGCAACCGGACGT
CCACGCCGTCGCTCCAAAGCCCTCAGAGCGTGCAGGTCGTGCCGCGCGCCGTCATCGAGGACCAGAACGCACTGAACCTC
GCCGAAGCGCTCCGCAACGTGTCCGGCGTGCAGTTCGATTTCGGGTTCAACGGGACGGCCATGCCGCTGGTCGTGCTGCG
AGGCTTTCCGAGCGTATCGATGACCGCCATGGGGCCGATGTCGGGCAGCTCGACCTACTACCTGGACGGCACCAAGGTCA
CCGGCGTCCCGATCAACATGGCCAACGTGCTGGCCGTCGAGGTGATCAAGGGGCCGTCGAGCGTCCTGTACGGGCGCGCC
GAACCGGGCGGGCTGGTCAACGTGGTCAGCAAGCCGATCAGCGTCGTGCCCGCCATGAGCCTGGAGCAGACCGTCGGGGA
GTACGGCCTGTCGCGCACGGCGGTGGAGGCATCCGGCCCTCTGAACGAGGAACGCAGTCTGCGTGGCCGGGCGTCCGCCT
CGTACTACACGGCCGATTCCATCCGCGACTTCGTCGAGGACAAGCTCGGCGCCTTCGGCGCCAGCCTGAGCTGGCTGCCC
AGCGCGCAGACCACCTTGACGGGAACGCTGGACTACAGCCACCAGCGCTACCGCACCGACTACGGCGTGCCGGCCTTGGG
CGACCGGCCCGCCGATCTGCCGTGGTCGCGGCAGTTCAACGACTCGCCGCAGCTCTCCAGCAGCAAGACCACCACCCTGA
AGCTGGAAGGCGAGCACCGCCTGTCCGAGGCCTGGCAGCTCAAGGGCAAGCTCCTGACCCTGCGCAGCGACACCTCCGAG
ATGGACATCTCGCCCTATCGCGCCGACTACGGCATGGGCATGACGCCCGACGCCACCTGCCCGGGCACGGGCAATCCGCT
GTGCCGCTACTACTTCTACGTGCGACCGGACGGGCGCTACCGGCTGGACCAGTTCAACCTCGACCTGATCGGCAAGATCG
ACACCGGCGGGATCCAGCACACCGTGTTGCTCGGCGTCGATGCCTACAGCGGCCGCAAGACCGGCACGACCTACTTCCAG
CAGATCGGCTCGGTGGACATCTACACGCCGGCGCTGGGCAGCACGCCGCCGCTGGACCTGGGCATGTCCATGCCGATGGA
CATCGAGGATCGCAACCGCTGGACCAGCATCTACGTGCAGGATCAACTGGCCCTGGGCCAGGGCGTCTTCCTGACCGCCG
CGTTGCGGCACGACCGCACCAGCGCCATCTACGCCGCCCCGGGCACCGAGCCCAACAAGGCTTCGTTCACCACGCCACGA
CTCGGTGCGGTCTGGCAGTTCGCCTCCAACCAGTCGATCTACGCCCAGTACCAGGACGCCGTGTCCGCCAACAACGGCCG
GGACACGGTGACCGGGGCCGCTCTCAGCGCCGAGCGCGCCAGGCAGTTCGAGATCGGCCACAAGATCGACTGGCTCGACG
GCAAGCTCAGTTCGACCCTTGCGGCGTACGAGCTGACCAAGCGCAACCGTGGGGGCTCGGTCCCGGTCGCGACGCCGCCC
TTCTACAACACCGTCACGGTGGGCGAAGCCCGCTCCCGTGGCGTCGAATGGGATCTTTCGGGGCAGGTCTCACGCAGTCT
GTCGCTGATCGCCTCCTATGCCTACACCGACACCCGCGTGCTGGTCGATCCGACCTACCAGGGCAAGAAGCTGGCCAACG
TGGCGCGGCATACCGGCAGCCTCTGGGCGCGCTACGCCATCGACAGCCAGTGGAGCACGGGTGCCGGCGTCTTTGCACAA
GGTCAGCGCCAGGGCGATACGGGCAATACCTTCCAGCTGCCGGGGTACGGACGGGTCGACGCCATGCTCGCCTACCGCTT
CGCGCTGCAGGATGCCCGGGCCGCGCTGCAGTTCAACGTCGACAACGTGTTCGATCGCAAGTACTACACGGGCAGCCATC
AGTTCGTGGCCGACTGGGTCAAGCTGGGGTCACCGCGGACAGTCAAGGCGACGCTGCGGCTGGATTACTAG

Upstream 100 bases:

>100_bases
TGGTGTCCCTGCCCGCAGCCTTGCCAAGCGCTTGAGCGATGCCTCGCGGGCGCCGTCGAGCGCTGCTCGCCGAGGTACCA
ACTTCTCCAGAGACGAACCC

Downstream 100 bases:

>100_bases
GAGAAACTCGCAATGCTGCATCGCCTAGCGCCGCCGCTGCTGGCCATCGCCCTGACCGGCTGCGGCGACCGTGCCGTGCC
CGAGGTACAGCCGCCGCCGA

Product: TonB-dependent receptor protein

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MNRLHRVSPLTFACLALAAHAQSEPPSQVLPPVQVQGQRDDYRAPETTTGNRTSTPSLQSPQSVQVVPRAVIEDQNALNL
AEALRNVSGVQFDFGFNGTAMPLVVLRGFPSVSMTAMGPMSGSSTYYLDGTKVTGVPINMANVLAVEVIKGPSSVLYGRA
EPGGLVNVVSKPISVVPAMSLEQTVGEYGLSRTAVEASGPLNEERSLRGRASASYYTADSIRDFVEDKLGAFGASLSWLP
SAQTTLTGTLDYSHQRYRTDYGVPALGDRPADLPWSRQFNDSPQLSSSKTTTLKLEGEHRLSEAWQLKGKLLTLRSDTSE
MDISPYRADYGMGMTPDATCPGTGNPLCRYYFYVRPDGRYRLDQFNLDLIGKIDTGGIQHTVLLGVDAYSGRKTGTTYFQ
QIGSVDIYTPALGSTPPLDLGMSMPMDIEDRNRWTSIYVQDQLALGQGVFLTAALRHDRTSAIYAAPGTEPNKASFTTPR
LGAVWQFASNQSIYAQYQDAVSANNGRDTVTGAALSAERARQFEIGHKIDWLDGKLSSTLAAYELTKRNRGGSVPVATPP
FYNTVTVGEARSRGVEWDLSGQVSRSLSLIASYAYTDTRVLVDPTYQGKKLANVARHTGSLWARYAIDSQWSTGAGVFAQ
GQRQGDTGNTFQLPGYGRVDAMLAYRFALQDARAALQFNVDNVFDRKYYTGSHQFVADWVKLGSPRTVKATLRLDY

Sequences:

>Translated_716_residues
MNRLHRVSPLTFACLALAAHAQSEPPSQVLPPVQVQGQRDDYRAPETTTGNRTSTPSLQSPQSVQVVPRAVIEDQNALNL
AEALRNVSGVQFDFGFNGTAMPLVVLRGFPSVSMTAMGPMSGSSTYYLDGTKVTGVPINMANVLAVEVIKGPSSVLYGRA
EPGGLVNVVSKPISVVPAMSLEQTVGEYGLSRTAVEASGPLNEERSLRGRASASYYTADSIRDFVEDKLGAFGASLSWLP
SAQTTLTGTLDYSHQRYRTDYGVPALGDRPADLPWSRQFNDSPQLSSSKTTTLKLEGEHRLSEAWQLKGKLLTLRSDTSE
MDISPYRADYGMGMTPDATCPGTGNPLCRYYFYVRPDGRYRLDQFNLDLIGKIDTGGIQHTVLLGVDAYSGRKTGTTYFQ
QIGSVDIYTPALGSTPPLDLGMSMPMDIEDRNRWTSIYVQDQLALGQGVFLTAALRHDRTSAIYAAPGTEPNKASFTTPR
LGAVWQFASNQSIYAQYQDAVSANNGRDTVTGAALSAERARQFEIGHKIDWLDGKLSSTLAAYELTKRNRGGSVPVATPP
FYNTVTVGEARSRGVEWDLSGQVSRSLSLIASYAYTDTRVLVDPTYQGKKLANVARHTGSLWARYAIDSQWSTGAGVFAQ
GQRQGDTGNTFQLPGYGRVDAMLAYRFALQDARAALQFNVDNVFDRKYYTGSHQFVADWVKLGSPRTVKATLRLDY
>Mature_716_residues
MNRLHRVSPLTFACLALAAHAQSEPPSQVLPPVQVQGQRDDYRAPETTTGNRTSTPSLQSPQSVQVVPRAVIEDQNALNL
AEALRNVSGVQFDFGFNGTAMPLVVLRGFPSVSMTAMGPMSGSSTYYLDGTKVTGVPINMANVLAVEVIKGPSSVLYGRA
EPGGLVNVVSKPISVVPAMSLEQTVGEYGLSRTAVEASGPLNEERSLRGRASASYYTADSIRDFVEDKLGAFGASLSWLP
SAQTTLTGTLDYSHQRYRTDYGVPALGDRPADLPWSRQFNDSPQLSSSKTTTLKLEGEHRLSEAWQLKGKLLTLRSDTSE
MDISPYRADYGMGMTPDATCPGTGNPLCRYYFYVRPDGRYRLDQFNLDLIGKIDTGGIQHTVLLGVDAYSGRKTGTTYFQ
QIGSVDIYTPALGSTPPLDLGMSMPMDIEDRNRWTSIYVQDQLALGQGVFLTAALRHDRTSAIYAAPGTEPNKASFTTPR
LGAVWQFASNQSIYAQYQDAVSANNGRDTVTGAALSAERARQFEIGHKIDWLDGKLSSTLAAYELTKRNRGGSVPVATPP
FYNTVTVGEARSRGVEWDLSGQVSRSLSLIASYAYTDTRVLVDPTYQGKKLANVARHTGSLWARYAIDSQWSTGAGVFAQ
GQRQGDTGNTFQLPGYGRVDAMLAYRFALQDARAALQFNVDNVFDRKYYTGSHQFVADWVKLGSPRTVKATLRLDY

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=690, Percent_Identity=28.1159420289855, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787344, Length=754, Percent_Identity=24.6684350132626, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1787024, Length=790, Percent_Identity=23.5443037974684, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78034; Mature: 78034

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLHRVSPLTFACLALAAHAQSEPPSQVLPPVQVQGQRDDYRAPETTTGNRTSTPSLQS
CCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
PQSVQVVPRAVIEDQNALNLAEALRNVSGVQFDFGFNGTAMPLVVLRGFPSVSMTAMGPM
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCEEEECCC
SGSSTYYLDGTKVTGVPINMANVLAVEVIKGPSSVLYGRAEPGGLVNVVSKPISVVPAMS
CCCCEEEECCCEEECCCCCHHHEEEEEEECCCCCEEEECCCCCCCHHHHHCCHHHCCCCH
LEQTVGEYGLSRTAVEASGPLNEERSLRGRASASYYTADSIRDFVEDKLGAFGASLSWLP
HHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCC
SAQTTLTGTLDYSHQRYRTDYGVPALGDRPADLPWSRQFNDSPQLSSSKTTTLKLEGEHR
CCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHH
LSEAWQLKGKLLTLRSDTSEMDISPYRADYGMGMTPDATCPGTGNPLCRYYFYVRPDGRY
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCE
RLDQFNLDLIGKIDTGGIQHTVLLGVDAYSGRKTGTTYFQQIGSVDIYTPALGSTPPLDL
EEEEECEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCC
GMSMPMDIEDRNRWTSIYVQDQLALGQGVFLTAALRHDRTSAIYAAPGTEPNKASFTTPR
CCCCCCCCCCCCCEEEEEEEECHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCC
LGAVWQFASNQSIYAQYQDAVSANNGRDTVTGAALSAERARQFEIGHKIDWLDGKLSSTL
CCEEEEECCCCCEEEHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCEEECCCCHHHHHH
AAYELTKRNRGGSVPVATPPFYNTVTVGEARSRGVEWDLSGQVSRSLSLIASYAYTDTRV
HHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHEECCCEE
LVDPTYQGKKLANVARHTGSLWARYAIDSQWSTGAGVFAQGQRQGDTGNTFQLPGYGRVD
EECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEECCCCCCHH
AMLAYRFALQDARAALQFNVDNVFDRKYYTGSHQFVADWVKLGSPRTVKATLRLDY
HHHHHHHHHHHHHEEEEECCCHHCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MNRLHRVSPLTFACLALAAHAQSEPPSQVLPPVQVQGQRDDYRAPETTTGNRTSTPSLQS
CCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
PQSVQVVPRAVIEDQNALNLAEALRNVSGVQFDFGFNGTAMPLVVLRGFPSVSMTAMGPM
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCEEEECCC
SGSSTYYLDGTKVTGVPINMANVLAVEVIKGPSSVLYGRAEPGGLVNVVSKPISVVPAMS
CCCCEEEECCCEEECCCCCHHHEEEEEEECCCCCEEEECCCCCCCHHHHHCCHHHCCCCH
LEQTVGEYGLSRTAVEASGPLNEERSLRGRASASYYTADSIRDFVEDKLGAFGASLSWLP
HHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCC
SAQTTLTGTLDYSHQRYRTDYGVPALGDRPADLPWSRQFNDSPQLSSSKTTTLKLEGEHR
CCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHH
LSEAWQLKGKLLTLRSDTSEMDISPYRADYGMGMTPDATCPGTGNPLCRYYFYVRPDGRY
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCE
RLDQFNLDLIGKIDTGGIQHTVLLGVDAYSGRKTGTTYFQQIGSVDIYTPALGSTPPLDL
EEEEECEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCC
GMSMPMDIEDRNRWTSIYVQDQLALGQGVFLTAALRHDRTSAIYAAPGTEPNKASFTTPR
CCCCCCCCCCCCCEEEEEEEECHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCC
LGAVWQFASNQSIYAQYQDAVSANNGRDTVTGAALSAERARQFEIGHKIDWLDGKLSSTL
CCEEEEECCCCCEEEHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCEEECCCCHHHHHH
AAYELTKRNRGGSVPVATPPFYNTVTVGEARSRGVEWDLSGQVSRSLSLIASYAYTDTRV
HHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHEECCCEE
LVDPTYQGKKLANVARHTGSLWARYAIDSQWSTGAGVFAQGQRQGDTGNTFQLPGYGRVD
EECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEECCCCCCHH
AMLAYRFALQDARAALQFNVDNVFDRKYYTGSHQFVADWVKLGSPRTVKATLRLDY
HHHHHHHHHHHHHEEEEECCCHHCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]