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The map label for this gene is acpS

Identifier: 124265847

GI number: 124265847

Start: 687090

End: 687488

Strand: Direct

Name: acpS

Synonym: Mpe_A0654

Alternate gene names: 124265847

Gene position: 687090-687488 (Clockwise)

Preceding gene: 124265846

Following gene: 124265848

Centisome position: 16.99

GC content: 68.67

Gene sequence:

>399_bases
ATGATCTTCGGGATCGGCACCGACATCTGCGACATCCGTCGCCTGCGCGCGACCTATGCACGTCGCGGCGAGCGCTTTGC
GGAGAAGGTGCTGGGCCCGCAGGAGCTCGAGGTGTTCCGCTACCGCCTGGCCAAGGTGGAGGCGCGGGGCCTCAGCTACC
TGGCCACGCGCTTCTCGGCCAAGGAGGCCTTCTCGAAGGCGATCGGCACCGGCATGCGCACGCCGATGAGCTGGCGTGCC
TGCCAGATCCTCAACGCGCGCAGCGGCAAGCCGGAGATCCGCCTGCACGGACCGCTGGCCGCCTGGTTCGAGGCACAGGG
CCTGCGCGCCCACGTCAGCGTCACCGACGAAACCGACTACGCGGCGAGCTTCGTCGTGGTCGAGACCCAGGAAACCTAG

Upstream 100 bases:

>100_bases
ATCGGCCACGCGCTGATCGCCGACGCGCTGGAACTGGGGCTGGCCGAGACGGTGCGCGACTACCTGCGCTGCATCCACCG
CGCCCACGCGTAGCCCCGGC

Downstream 100 bases:

>100_bases
ATGAACCACGCCCCCATCGTCCTCGACATCGCGGGGACCGCGCTCGATGCCAACGACCGGCGCCGCCTGCGTCACCCGCT
GGTCGGCGGGCTGATCCTGT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSAKEAFSKAIGTGMRTPMSWRA
CQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDYAASFVVVETQET

Sequences:

>Translated_132_residues
MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSAKEAFSKAIGTGMRTPMSWRA
CQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDYAASFVVVETQET
>Mature_132_residues
MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSAKEAFSKAIGTGMRTPMSWRA
CQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDYAASFVVVETQET

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=129, Percent_Identity=37.2093023255814, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_METPP (A2SDH7)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019851.1
- ProteinModelPortal:   A2SDH7
- SMR:   A2SDH7
- STRING:   A2SDH7
- GeneID:   4784781
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0654
- NMPDR:   fig|279263.3.peg.3218
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   A2SDH7
- ProtClustDB:   PRK00070
- BioCyc:   MPET420662:MPE_A0654-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14842; Mature: 14842

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KEAFSKAIGTGMRTPMSWRACQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDY
HHHHHHHHHCCCCCCCCCHHHHEECCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCC
AASFVVVETQET
CEEEEEEEECCC
>Mature Secondary Structure
MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KEAFSKAIGTGMRTPMSWRACQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDY
HHHHHHHHHCCCCCCCCCHHHHEECCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCC
AASFVVVETQET
CEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA