Click here to switch to the map view.

The map label for this gene is pdxJ [H]

Identifier: 124265846

GI number: 124265846

Start: 686285

End: 687082

Strand: Direct

Name: pdxJ [H]

Synonym: Mpe_A0653

Alternate gene names: 124265846

Gene position: 686285-687082 (Clockwise)

Preceding gene: 124265845

Following gene: 124265847

Centisome position: 16.97

GC content: 69.67

Gene sequence:

>798_bases
ATGAATCCGCTGATCTCCTCCGGCCATGCTTTCCACGCCGCGACGACCGCGCTGTCGGTCAACCTGAACAAGGTTGCGCT
GCTGCGCAACACGCGGCCGCTGACGATCCCGAGCGTCACGCGTGCCGCCCGCATCGCGATCGACGCGGGGGCGCACGGCA
TCACCGTGCACCCGCGGCCCGACCAGCGCCACATCCGCACCCACGACGTGCACGACCTGGCCGAGATGCTGAAGCAGGAG
CATCCGCACATCGAATACAACATCGAAGGCAATCCCTTCCACAACCTGATGGACCTTGTGCGTGTGGTGCGTCCGCACCA
GGCCACCTTCGTGCCCGACAGCGTCGAGCAGTCCACCTCCGACCACGGCTGGAGCCTGCCCGAGGACAACGAGGCGCTGA
GACCGCTGATCGACGAATGCCATGCGCTCGGCGTGCGCGTCAGCCTGTTCATGGACCCGCTGCCCGAGGCGATGGCCCAG
GCCCGTGCCATCGGGGCCGACCGCGTCGAGCTCTACACCGAGGCCTATGCGCGCTCGCATGCCGAAGGCGCCGGCACGCC
GCAGCATGCCGCGCTGCTGGCCTGCTACACCGCCAGCGCCGAGGCCGCGCTGGGCGTCGGCCTTGGGCTCAACGCCGGCC
ACGACCTGAACCGCGACAACCTGACCGCCTTCCTCCGCGCCGTGCCCGGCGTGCTGGAGGTGTCGATCGGCCACGCGCTG
ATCGCCGACGCGCTGGAACTGGGGCTGGCCGAGACGGTGCGCGACTACCTGCGCTGCATCCACCGCGCCCACGCGTAG

Upstream 100 bases:

>100_bases
GCGCAACCTGCTTCACTATCATCTGGCCACGCCGGTGCTGCGCACGCGGCAGTTGATGATGGACCTGCAGAACCTCGACC
GCTGACGAGCTGACGTTTCG

Downstream 100 bases:

>100_bases
CCCCGGCATGATCTTCGGGATCGGCACCGACATCTGCGACATCCGTCGCCTGCGCGCGACCTATGCACGTCGCGGCGAGC
GCTTTGCGGAGAAGGTGCTG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNPLISSGHAFHAATTALSVNLNKVALLRNTRPLTIPSVTRAARIAIDAGAHGITVHPRPDQRHIRTHDVHDLAEMLKQE
HPHIEYNIEGNPFHNLMDLVRVVRPHQATFVPDSVEQSTSDHGWSLPEDNEALRPLIDECHALGVRVSLFMDPLPEAMAQ
ARAIGADRVELYTEAYARSHAEGAGTPQHAALLACYTASAEAALGVGLGLNAGHDLNRDNLTAFLRAVPGVLEVSIGHAL
IADALELGLAETVRDYLRCIHRAHA

Sequences:

>Translated_265_residues
MNPLISSGHAFHAATTALSVNLNKVALLRNTRPLTIPSVTRAARIAIDAGAHGITVHPRPDQRHIRTHDVHDLAEMLKQE
HPHIEYNIEGNPFHNLMDLVRVVRPHQATFVPDSVEQSTSDHGWSLPEDNEALRPLIDECHALGVRVSLFMDPLPEAMAQ
ARAIGADRVELYTEAYARSHAEGAGTPQHAALLACYTASAEAALGVGLGLNAGHDLNRDNLTAFLRAVPGVLEVSIGHAL
IADALELGLAETVRDYLRCIHRAHA
>Mature_265_residues
MNPLISSGHAFHAATTALSVNLNKVALLRNTRPLTIPSVTRAARIAIDAGAHGITVHPRPDQRHIRTHDVHDLAEMLKQE
HPHIEYNIEGNPFHNLMDLVRVVRPHQATFVPDSVEQSTSDHGWSLPEDNEALRPLIDECHALGVRVSLFMDPLPEAMAQ
ARAIGADRVELYTEAYARSHAEGAGTPQHAALLACYTASAEAALGVGLGLNAGHDLNRDNLTAFLRAVPGVLEVSIGHAL
IADALELGLAETVRDYLRCIHRAHA

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=249, Percent_Identity=33.7349397590361, Blast_Score=118, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 28733; Mature: 28733

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLISSGHAFHAATTALSVNLNKVALLRNTRPLTIPSVTRAARIAIDAGAHGITVHPRP
CCCCCCCCCCHHHHHHEEEECCCEEEEEECCCCCCCCCHHHHHHEEEECCCCCEEECCCC
DQRHIRTHDVHDLAEMLKQEHPHIEYNIEGNPFHNLMDLVRVVRPHQATFVPDSVEQSTS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCC
DHGWSLPEDNEALRPLIDECHALGVRVSLFMDPLPEAMAQARAIGADRVELYTEAYARSH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
AEGAGTPQHAALLACYTASAEAALGVGLGLNAGHDLNRDNLTAFLRAVPGVLEVSIGHAL
CCCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
IADALELGLAETVRDYLRCIHRAHA
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPLISSGHAFHAATTALSVNLNKVALLRNTRPLTIPSVTRAARIAIDAGAHGITVHPRP
CCCCCCCCCCHHHHHHEEEECCCEEEEEECCCCCCCCCHHHHHHEEEECCCCCEEECCCC
DQRHIRTHDVHDLAEMLKQEHPHIEYNIEGNPFHNLMDLVRVVRPHQATFVPDSVEQSTS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCC
DHGWSLPEDNEALRPLIDECHALGVRVSLFMDPLPEAMAQARAIGADRVELYTEAYARSH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
AEGAGTPQHAALLACYTASAEAALGVGLGLNAGHDLNRDNLTAFLRAVPGVLEVSIGHAL
CCCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
IADALELGLAETVRDYLRCIHRAHA
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA